The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
155
|
sequence length |
461
|
structure length |
440
|
Chain Sequence |
b'ASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKAEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYGDAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLA'
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
pubmed doi rcsb |
molecule keywords |
Tryptophanyl-tRNA synthetase
|
source organism |
Homo sapiens
|
molecule tags |
Ligase
|
total genus |
155
|
structure length |
440
|
sequence length |
461
|
chains with identical sequence |
B
|
ec nomenclature |
ec
6.1.1.2: Tryptophan--tRNA ligase. |
pdb deposition date | 2003-10-16 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
A | PF00458 | WHEP-TRS | WHEP-TRS domain |
A | PF00579 | tRNA-synt_1b | tRNA synthetases class I (W and Y) |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Mainly Alpha | Orthogonal Bundle | Tyrosyl-Transfer RNA Synthetase | Tyrosyl-Transfer RNA Synthetase | ||
Mainly Alpha | Orthogonal Bundle | Helix Hairpins | S15/NS1, RNA-binding | ||
Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | HUPs |