1RF7A

Structure of dihydrofolate reductase complexed with dihydrofolate
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
pubmed doi rcsb
molecule keywords DIHYDROFOLATE REDUCTASE
molecule tags Oxidoreductase
source organism Escherichia coli
total genus 46
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1rf7A00
4FGGA 3HBBA 5HVEA 1PD9A 3DRCA 4XT7A 4P3QA 2OBCA 1U70A 1JOLA 1JUVA 3IA5A 3F0VX 3GHVA 4M7UA 4RGCA 2BL9A 1S3YA 3NXXA 4XE6X 3FL9A 4KJKA 2C2SA 4M7VA 4X5GA 3TQBA 1RX8A 1J3IA 3QLYA 3FYVX 2GD9A 4ELEA 5HI6A 3CLBA 4KAKA 5HT5A 4XT8A 4PSTA 1DAJA 4CD2A 6DFRA 4IXGX 3ZPCA 4EJ1A 4LAHX 5HF2X 1RA8A 1RX1A 3F91A 4KY4A 4QI9A 3FRAX 3SRUX 3JWKA 1RB3A 1QZFA 3NZ6X 2FZHA 3NZCX 3ZPGA 1OHKA 3RG9A 3FRBX 1HFQA 3DAUA 3SA2A 3QYOA 3SRWX 1DYHA 1VJ3A 1IA4A 4QLEA 3OCHA 1BOZA 1RH3A 3M09A 3SGYA 2DRCA 1AOEA 3F0UX 3FQFA 2FZJA 5HVBA 4HOFA 3KJSA 1RX6A 1DLRA 4EIZA 5HT4A 4X5JA 1DR2A 3S9UA 1RX4A 5CC9A 2W3AA 3NZ9X 4ELFA 3K74A 3R33A 4P68A 2HM9A 3QLWA 3Q1HA 1DHIA 3EIGA 3JWCA 2FZIA 3ROAA 3FQCA 2XW7A 1DR5A 3DG8A 3QLZA 4P3RA 1DRBA 4KY8A 3F8ZA 2AZNA 2QK8A 1DG7A 4P66A 3NTZA 1HFPA 4IXED 4KYAA 4X5FA 4LAGX 3GHCA 4EILA 1DLSA 1RE7A 4FGHA 3L3RA 2HQPA 3NRRA 4KNEA 3DATA 3VCOA 3SAIA 3OAFA 4IXFX 1DF7A 3IROA 2JYBA 1VDRA 3EEKA 1DDRA 4M6LA 4M6KA 3JSUA 3QYLA 4KFJA 1AO8A 4H96A 2B3ZA 3FREX 3F0QX 4QLGA 4XT6A 3SRSX 3INVA 1DG8A 3QLXA 2W3VA 3SQYX 4HA7A 3FYWX 1CZ3A 3FY8X 3SR5X 3DL6A 4Q6AA 3FY9X 1J3KA 3NU0A 1M79A 4KJJA 3NXTA 3I3RA 1DR6A 4DPDA 4PSSA 3QLRA 2ANOA 4KD7A 4NX6A 3QL0A 3F0SX 3KGYA 1RA9A 3GHWA 3D84X 2P4GA 4GH8A 1SEJA 2ITHA 3JWFA 3QL3A 3TQAA 1IA2A 3FQ0A 2ZZAA 4KBNA 3FL8A 3NZDA 2BLBA 5CCCA 2W3WA 4M6JA 3TQ8A 4HOGA 2BLAA 4PTJA 1J3JA 2INQA 3F8YA 1DR3A 2DHFA 1DDSA 3NXYA 3DFRA 3NXOA 1S3UA 4DP3A 3KJRA 1D1GA 4QHVA 1DR4A 3EEMA 4ELBA 1YHOA 2G6VA 3UM6A 3DGAA 1MVSA 4ELHA 4PTHA 4KM0A 3EEJA 3FQZA 4Q0DA 2C2TA 2HXVA 3SA1A 1RA2A 5HSUA 2CD2A 5U26A 1DYIA 3TD8A 1KLKA 4OSGA 3QLSA 3DL5A 8DFRA 5JA3A 1RX9A 1ZDRA 4KJLA 2W9GA 4H98A 4FHBA 1JOMA 3RO9A 3EX8A 4QLFA 4HOEA 3FRFX 4QJCA 5JG0X 1M78A 1DR1A 4X5HA 4I1NA 3JTWA 1DHJA 3NZAX 1OHJA 1LY4A 2W3BA 1LY3A 2D0KA 4DFRA 5DXVA 5HUIA 3HJ3A 3KFYA 2O7PA 3I8AX 3IRMA 3IX9A 4H97A 3K47A 5ECXA 1E26A 3UM5A 1RA3A 4NX7A 4LEKX 3S3VA 1IA3A 4M2XA 3K45A 5HSRA 1DIUA 1DR7A 3M08A 2CIGA 1RX3A 4ELGA 1HFRA 3GYFA 4KL9A 4G3MA 5HF0X 1DYRA 3NXVA 4KM2A 4XRBA 3IRNA 1RX5A 1RF7A 1DISA 2W3MA 4G95A 4XT5A 4LAEX 1MVTA 3IA4A 3JW5A 3FS6A 5ECCA 3E0BA 3FRDX 1DG5A 1RC4A 4EIGA 5HPBA 1RX2A 3F0BX 3QFXA 1U72A 3SRQX 3EELA 1U71A 1S3VA 2LF1A 2D5NA 4DPHA 5E8QA 4KEBA 1RA1A 4HA9A 4Q67A 3NZBX 3KY8A 2W9TA 3QGTA 5U27A 3CSEA 7DFRA 4OR7A 3SH2A 3N0HA 1M7AA 2L28A 1KMVA 1AI9A 4QJZD 3JW3A 5FDAA 4PSYA 4XT4A 1IA1A 1TDRA 3D80A 4DDRA 4H95A 3F0XX 1RD7A 2BLCA 4PDJA 1RG7A 4KLXA 1DRAA 3QG2A 3LG4A 3JWMA 1BZFA 4Q0EA 1LUDA 1RB2A 3CD2A 3JVXA 1KMSA 2KGKA 5DFRA 3S7AA 3FQOA 1CD2A 3CL9A 5HQZA 2W9HA 3FQVA 4I13A 1DREA 1DYJA 5EAJA 2H2QA 1S3WA 2ANQA 4G8ZX 3SRRX 3TQ9A 2OIPA 1RX7A 2W9SA 1DRHA 5HQYA 3GI2A 3NXRA 4XECX 1PDBA 3UM8A 1DHFA 1PD8A 4TU5X 3K2HA 1DRFA 4X5IA 4ECKA
chains in the Genus database with same CATH superfamily
4FGGA 3HBBA 5HVEA 1PD9A 3DRCA 4XT7A 4P3QA 2OBCA 1U70A 1JOLA 1JUVA 3IA5A 3F0VX 3GHVA 4M7UA 4RGCA 2BL9A 1S3YA 3NXXA 4XE6X 3FL9A 4KJKA 2C2SA 4M7VA 4X5GA 3TQBA 1RX8A 1J3IA 3QLYA 3FYVX 2GD9A 4ELEA 5HI6A 3CLBA 4KAKA 5HT5A 4XT8A 4PSTA 1DAJA 4CD2A 6DFRA 4IXGX 3ZPCA 4EJ1A 4LAHX 5HF2X 1RA8A 1RX1A 3F91A 4KY4A 4QI9A 3FRAX 3SRUX 3JWKA 1RB3A 1QZFA 3NZ6X 2FZHA 3NZCX 3ZPGA 1OHKA 3RG9A 3FRBX 1HFQA 3DAUA 3SA2A 3QYOA 3SRWX 1DYHA 1VJ3A 1IA4A 4QLEA 3OCHA 1BOZA 1RH3A 3M09A 3SGYA 2DRCA 1AOEA 3F0UX 3FQFA 2FZJA 5HVBA 4HOFA 3KJSA 1RX6A 1DLRA 4EIZA 5HT4A 4X5JA 1DR2A 3S9UA 1RX4A 5CC9A 2W3AA 3NZ9X 4ELFA 3K74A 3R33A 4P68A 2HM9A 3QLWA 3Q1HA 1DHIA 3EIGA 3JWCA 2FZIA 3ROAA 3FQCA 2XW7A 1DR5A 3DG8A 3QLZA 4P3RA 1DRBA 4KY8A 3F8ZA 2AZNA 2QK8A 1DG7A 4P66A 3NTZA 1HFPA 4IXED 4KYAA 4X5FA 4LAGX 3GHCA 4EILA 1DLSA 1RE7A 4FGHA 3L3RA 2HQPA 3NRRA 4KNEA 3DATA 3VCOA 3SAIA 3OAFA 4IXFX 1DF7A 3IROA 2JYBA 1VDRA 3EEKA 1DDRA 4M6LA 4M6KA 3JSUA 3QYLA 4KFJA 1AO8A 4H96A 2B3ZA 3FREX 3F0QX 4QLGA 4XT6A 3SRSX 3INVA 1DG8A 3QLXA 2W3VA 3SQYX 4HA7A 3FYWX 1CZ3A 3FY8X 3SR5X 3DL6A 4Q6AA 3FY9X 1J3KA 3NU0A 1M79A 4KJJA 3NXTA 3I3RA 1DR6A 4DPDA 4PSSA 3QLRA 2ANOA 4KD7A 4NX6A 3QL0A 3F0SX 3KGYA 1RA9A 3GHWA 3D84X 2P4GA 4GH8A 1SEJA 2ITHA 3JWFA 3QL3A 3TQAA 1IA2A 3FQ0A 2ZZAA 4KBNA 3FL8A 3NZDA 2BLBA 5CCCA 2W3WA 4M6JA 3TQ8A 4HOGA 2BLAA 4PTJA 1J3JA 2INQA 3F8YA 1DR3A 2DHFA 1DDSA 3NXYA 3DFRA 3NXOA 1S3UA 4DP3A 3KJRA 1D1GA 4QHVA 1DR4A 3EEMA 4ELBA 1YHOA 2G6VA 3UM6A 3DGAA 1MVSA 4ELHA 4PTHA 4KM0A 3EEJA 3FQZA 4Q0DA 2C2TA 2HXVA 3SA1A 1RA2A 5HSUA 2CD2A 5U26A 1DYIA 3TD8A 1KLKA 4OSGA 3QLSA 3DL5A 8DFRA 5JA3A 1RX9A 1ZDRA 4KJLA 2W9GA 4H98A 4FHBA 1JOMA 3RO9A 3EX8A 4QLFA 4HOEA 3FRFX 4QJCA 5JG0X 1M78A 1DR1A 4X5HA 4I1NA 3JTWA 1DHJA 3NZAX 1OHJA 1LY4A 2W3BA 1LY3A 2D0KA 4DFRA 5DXVA 5HUIA 3HJ3A 3KFYA 2O7PA 3I8AX 3IRMA 3IX9A 4H97A 3K47A 5ECXA 1E26A 3UM5A 1RA3A 4NX7A 4LEKX 3S3VA 1IA3A 4M2XA 3K45A 5HSRA 1DIUA 1DR7A 3M08A 2CIGA 1RX3A 4ELGA 1HFRA 3GYFA 4KL9A 4G3MA 5HF0X 1DYRA 3NXVA 4KM2A 4XRBA 3IRNA 1RX5A 1RF7A 1DISA 2W3MA 4G95A 4XT5A 4LAEX 1MVTA 3IA4A 3JW5A 3FS6A 5ECCA 3E0BA 3FRDX 1DG5A 1RC4A 4EIGA 5HPBA 1RX2A 3F0BX 3QFXA 1U72A 3SRQX 3EELA 1U71A 1S3VA 2LF1A 2D5NA 4DPHA 5E8QA 4KEBA 1RA1A 4HA9A 4Q67A 3NZBX 3KY8A 2W9TA 3QGTA 5U27A 3CSEA 7DFRA 4OR7A 3SH2A 3N0HA 1M7AA 2L28A 1KMVA 1AI9A 4QJZD 3JW3A 5FDAA 4PSYA 4XT4A 1IA1A 1TDRA 3D80A 4DDRA 4H95A 3F0XX 1RD7A 2BLCA 4PDJA 1RG7A 4KLXA 1DRAA 3QG2A 3LG4A 3JWMA 1BZFA 4Q0EA 1LUDA 1RB2A 3CD2A 3JVXA 1KMSA 2KGKA 5DFRA 3S7AA 3FQOA 1CD2A 3CL9A 5HQZA 2W9HA 3FQVA 4I13A 1DREA 1DYJA 5EAJA 2H2QA 1S3WA 2ANQA 4G8ZX 3SRRX 3TQ9A 2OIPA 1RX7A 2W9SA 1DRHA 5HQYA 3GI2A 3NXRA 4XECX 1PDBA 3UM8A 1DHFA 1PD8A 4TU5X 3K2HA 1DRFA 4X5IA 4ECKA
chains in the Genus database with same CATH topology
4FGGA 3HBBA 5HVEA 1PD9A 3DRCA 4XT7A 4P3QA 2OBCA 1U70A 1JOLA 1JUVA 3IA5A 3F0VX 3GHVA 4M7UA 4RGCA 2BL9A 1S3YA 3NXXA 4XE6X 3FL9A 4KJKA 2C2SA 4M7VA 4X5GA 3TQBA 1RX8A 1J3IA 3QLYA 3FYVX 2GD9A 4ELEA 5HI6A 3CLBA 4KAKA 5HT5A 4XT8A 4PSTA 1DAJA 4CD2A 6DFRA 4IXGX 3ZPCA 4EJ1A 4LAHX 5HF2X 1RA8A 1RX1A 3F91A 4KY4A 4QI9A 3FRAX 3SRUX 3JWKA 1RB3A 1QZFA 3NZ6X 2FZHA 3NZCX 3ZPGA 1OHKA 3RG9A 3FRBX 1HFQA 3DAUA 3SA2A 3QYOA 3SRWX 1DYHA 1VJ3A 1IA4A 4QLEA 3OCHA 1BOZA 1RH3A 3M09A 3SGYA 2DRCA 1AOEA 3F0UX 3FQFA 2FZJA 5HVBA 4HOFA 3KJSA 1RX6A 1DLRA 4EIZA 5HT4A 4X5JA 1DR2A 3S9UA 1RX4A 5CC9A 2W3AA 3NZ9X 4ELFA 3K74A 3R33A 4P68A 2HM9A 3QLWA 3Q1HA 1DHIA 3EIGA 3JWCA 2FZIA 3ROAA 3FQCA 2XW7A 1DR5A 3DG8A 3QLZA 4P3RA 1DRBA 4KY8A 3F8ZA 2AZNA 2QK8A 1DG7A 4P66A 3NTZA 1HFPA 4IXED 4KYAA 4X5FA 4LAGX 3GHCA 4EILA 1DLSA 1RE7A 4FGHA 3L3RA 2HQPA 3NRRA 4KNEA 3DATA 3VCOA 3SAIA 3OAFA 4IXFX 1DF7A 3IROA 2JYBA 1VDRA 3EEKA 1DDRA 4M6LA 4M6KA 3JSUA 3QYLA 4KFJA 1AO8A 4H96A 2B3ZA 3FREX 3F0QX 4QLGA 4XT6A 3SRSX 3INVA 1DG8A 3QLXA 2W3VA 3SQYX 4HA7A 3FYWX 1CZ3A 3FY8X 3SR5X 3DL6A 4Q6AA 3FY9X 1J3KA 3NU0A 1M79A 4KJJA 3NXTA 3I3RA 1DR6A 4DPDA 4PSSA 3QLRA 2ANOA 4KD7A 4NX6A 3QL0A 3F0SX 3KGYA 1RA9A 3GHWA 3D84X 2P4GA 4GH8A 1SEJA 2ITHA 3JWFA 3QL3A 3TQAA 1IA2A 3FQ0A 2ZZAA 4KBNA 3FL8A 3NZDA 2BLBA 5CCCA 2W3WA 4M6JA 3TQ8A 4HOGA 2BLAA 4PTJA 1J3JA 2INQA 3F8YA 1DR3A 2DHFA 1DDSA 3NXYA 3DFRA 3NXOA 1S3UA 4DP3A 3KJRA 1D1GA 4QHVA 1DR4A 3EEMA 4ELBA 1YHOA 2G6VA 3UM6A 3DGAA 1MVSA 4ELHA 4PTHA 4KM0A 3EEJA 3FQZA 4Q0DA 2C2TA 2HXVA 3SA1A 1RA2A 5HSUA 2CD2A 5U26A 1DYIA 3TD8A 1KLKA 4OSGA 3QLSA 3DL5A 8DFRA 5JA3A 1RX9A 1ZDRA 4KJLA 2W9GA 4H98A 4FHBA 1JOMA 3RO9A 3EX8A 4QLFA 4HOEA 3FRFX 4QJCA 5JG0X 1M78A 1DR1A 4X5HA 4I1NA 3JTWA 1DHJA 3NZAX 1OHJA 1LY4A 2W3BA 1LY3A 2D0KA 4DFRA 5DXVA 5HUIA 3HJ3A 3KFYA 2O7PA 3I8AX 3IRMA 3IX9A 4H97A 3K47A 5ECXA 1E26A 3UM5A 1RA3A 4NX7A 4LEKX 3S3VA 1IA3A 4M2XA 3K45A 5HSRA 1DIUA 1DR7A 3M08A 2CIGA 1RX3A 4ELGA 1HFRA 3GYFA 4KL9A 4G3MA 5HF0X 1DYRA 3NXVA 4KM2A 4XRBA 3IRNA 1RX5A 1RF7A 1DISA 2W3MA 4G95A 4XT5A 4LAEX 1MVTA 3IA4A 3JW5A 3FS6A 5ECCA 3E0BA 3FRDX 1DG5A 1RC4A 4EIGA 5HPBA 1RX2A 3F0BX 3QFXA 1U72A 3SRQX 3EELA 1U71A 1S3VA 2LF1A 2D5NA 4DPHA 5E8QA 4KEBA 1RA1A 4HA9A 4Q67A 3NZBX 3KY8A 2W9TA 3QGTA 5U27A 3CSEA 7DFRA 4OR7A 3SH2A 3N0HA 1M7AA 2L28A 1KMVA 1AI9A 4QJZD 3JW3A 5FDAA 4PSYA 4XT4A 1IA1A 1TDRA 3D80A 4DDRA 4H95A 3F0XX 1RD7A 2BLCA 4PDJA 1RG7A 4KLXA 1DRAA 3QG2A 3LG4A 3JWMA 1BZFA 4Q0EA 1LUDA 1RB2A 3CD2A 3JVXA 1KMSA 2KGKA 5DFRA 3S7AA 3FQOA 1CD2A 3CL9A 5HQZA 2W9HA 3FQVA 4I13A 1DREA 1DYJA 5EAJA 2H2QA 1S3WA 2ANQA 4G8ZX 3SRRX 3TQ9A 2OIPA 1RX7A 2W9SA 1DRHA 5HQYA 3GI2A 3NXRA 4XECX 1PDBA 3UM8A 1DHFA 1PD8A 4TU5X 3K2HA 1DRFA 4X5IA 4ECKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FGG A;  3HBB A;  5HVE A;  1PD9 A;  3DRC A;  4XT7 A;  4P3Q A;  2OBC A;  1U70 A;  1JOL A;  1JUV A;  3IA5 A;  3F0V X;  3GHV A;  4M7U A;  4RGC A;  2BL9 A;  1S3Y A;  3NXX A;  4XE6 X;  3FL9 A;  4KJK A;  2C2S A;  4M7V A;  4X5G A;  3TQB A;  1RX8 A;  1J3I A;  3QLY A;  3FYV X;  2GD9 A;  4ELE A;  5HI6 A;  3CLB A;  4KAK A;  5HT5 A;  4XT8 A;  4PST A;  1DAJ A;  4CD2 A;  6DFR A;  4IXG X;  3ZPC A;  4EJ1 A;  4LAH X;  5HF2 X;  1RA8 A;  1RX1 A;  3F91 A;  4KY4 A;  4QI9 A;  3FRA X;  3SRU X;  3JWK A;  1RB3 A;  1QZF A;  3NZ6 X;  2FZH A;  3NZC X;  3ZPG A;  1OHK A;  3RG9 A;  3FRB X;  1HFQ A;  3DAU A;  3SA2 A;  3QYO A;  3SRW X;  1DYH A;  1VJ3 A;  1IA4 A;  4QLE A;  3OCH A;  1BOZ A;  1RH3 A;  3M09 A;  3SGY A;  2DRC A;  1AOE A;  3F0U X;  3FQF A;  2FZJ A;  5HVB A;  4HOF A;  3KJS A;  1RX6 A;  1DLR A;  4EIZ A;  5HT4 A;  4X5J A;  1DR2 A;  3S9U A;  1RX4 A;  5CC9 A;  2W3A A;  3NZ9 X;  4ELF A;  3K74 A;  3R33 A;  4P68 A;  2HM9 A;  3QLW A;  3Q1H A;  1DHI A;  3EIG A;  3JWC A;  2FZI A;  3ROA A;  3FQC A;  2XW7 A;  1DR5 A;  3DG8 A;  3QLZ A;  4P3R A;  1DRB A;  4KY8 A;  3F8Z A;  2AZN A;  2QK8 A;  1DG7 A;  4P66 A;  3NTZ A;  1HFP A;  4IXE D;  4KYA A;  4X5F A;  4LAG X;  3GHC A;  4EIL A;  1DLS A;  1RE7 A;  4FGH A;  3L3R A;  2HQP A;  3NRR A;  4KNE A;  3DAT A;  3VCO A;  3SAI A;  3OAF A;  4IXF X;  1DF7 A;  3IRO A;  2JYB A;  1VDR A;  3EEK A;  1DDR A;  4M6L A;  4M6K A;  3JSU A;  3QYL A;  4KFJ A;  1AO8 A;  4H96 A;  2B3Z A;  3FRE X;  3F0Q X;  4QLG A;  4XT6 A;  3SRS X;  3INV A;  1DG8 A;  3QLX A;  2W3V A;  3SQY X;  4HA7 A;  3FYW X;  1CZ3 A;  3FY8 X;  3SR5 X;  3DL6 A;  4Q6A A;  3FY9 X;  1J3K A;  3NU0 A;  1M79 A;  4KJJ A;  3NXT A;  3I3R A;  1DR6 A;  4DPD A;  4PSS A;  3QLR A;  2ANO A;  4KD7 A;  4NX6 A;  3QL0 A;  3F0S X;  3KGY A;  1RA9 A;  3GHW A;  3D84 X;  2P4G A;  4GH8 A;  1SEJ A;  2ITH A;  3JWF A;  3QL3 A;  3TQA A;  1IA2 A;  3FQ0 A;  2ZZA A;  4KBN A;  3FL8 A;  3NZD A;  2BLB A;  5CCC A;  2W3W A;  4M6J A;  3TQ8 A;  4HOG A;  2BLA A;  4PTJ A;  1J3J A;  2INQ A;  3F8Y A;  1DR3 A;  2DHF A;  1DDS A;  3NXY A;  3DFR A;  3NXO A;  1S3U A;  4DP3 A;  3KJR A;  1D1G A;  4QHV A;  1DR4 A;  3EEM A;  4ELB A;  1YHO A;  2G6V A;  3UM6 A;  3DGA A;  1MVS A;  4ELH A;  4PTH A;  4KM0 A;  3EEJ A;  3FQZ A;  4Q0D A;  2C2T A;  2HXV A;  3SA1 A;  1RA2 A;  5HSU A;  2CD2 A;  5U26 A;  1DYI A;  3TD8 A;  1KLK A;  4OSG A;  3QLS A;  3DL5 A;  8DFR A;  5JA3 A;  1RX9 A;  1ZDR A;  4KJL A;  2W9G A;  4H98 A;  4FHB A;  1JOM A;  3RO9 A;  3EX8 A;  4QLF A;  4HOE A;  3FRF X;  4QJC A;  5JG0 X;  1M78 A;  1DR1 A;  4X5H A;  4I1N A;  3JTW A;  1DHJ A;  3NZA X;  1OHJ A;  1LY4 A;  2W3B A;  1LY3 A;  2D0K A;  4DFR A;  5DXV A;  5HUI A;  3HJ3 A;  3KFY A;  2O7P A;  3I8A X;  3IRM A;  3IX9 A;  4H97 A;  3K47 A;  5ECX A;  1E26 A;  3UM5 A;  1RA3 A;  4NX7 A;  4LEK X;  3S3V A;  1IA3 A;  4M2X A;  3K45 A;  5HSR A;  1DIU A;  1DR7 A;  3M08 A;  2CIG A;  1RX3 A;  4ELG A;  1HFR A;  3GYF A;  4KL9 A;  4G3M A;  5HF0 X;  1DYR A;  3NXV A;  4KM2 A;  4XRB A;  3IRN A;  1RX5 A;  1RF7 A;  1DIS A;  2W3M A;  4G95 A;  4XT5 A;  4LAE X;  1MVT A;  3IA4 A;  3JW5 A;  3FS6 A;  5ECC A;  3E0B A;  3FRD X;  1DG5 A;  1RC4 A;  4EIG A;  5HPB A;  1RX2 A;  3F0B X;  3QFX A;  1U72 A;  3SRQ X;  3EEL A;  1U71 A;  1S3V A;  2LF1 A;  2D5N A;  4DPH A;  5E8Q A;  4KEB A;  1RA1 A;  4HA9 A;  4Q67 A;  3NZB X;  3KY8 A;  2W9T A;  3QGT A;  5U27 A;  3CSE A;  7DFR A;  4OR7 A;  3SH2 A;  3N0H A;  1M7A A;  2L28 A;  1KMV A;  1AI9 A;  4QJZ D;  3JW3 A;  5FDA A;  4PSY A;  4XT4 A;  1IA1 A;  1TDR A;  3D80 A;  4DDR A;  4H95 A;  3F0X X;  1RD7 A;  2BLC A;  4PDJ A;  1RG7 A;  4KLX A;  1DRA A;  3QG2 A;  3LG4 A;  3JWM A;  1BZF A;  4Q0E A;  1LUD A;  1RB2 A;  3CD2 A;  3JVX A;  1KMS A;  2KGK A;  5DFR A;  3S7A A;  3FQO A;  1CD2 A;  3CL9 A;  5HQZ A;  2W9H A;  3FQV A;  4I13 A;  1DRE A;  1DYJ A;  5EAJ A;  2H2Q A;  1S3W A;  2ANQ A;  4G8Z X;  3SRR X;  3TQ9 A;  2OIP A;  1RX7 A;  2W9S A;  1DRH A;  5HQY A;  3GI2 A;  3NXR A;  4XEC X;  1PDB A;  3UM8 A;  1DHF A;  1PD8 A;  4TU5 X;  3K2H A;  1DRF A;  4X5I A;  4ECK A; 
#chains in the Genus database with same CATH topology
 4FGG A;  3HBB A;  5HVE A;  1PD9 A;  3DRC A;  4XT7 A;  4P3Q A;  2OBC A;  1U70 A;  1JOL A;  1JUV A;  3IA5 A;  3F0V X;  3GHV A;  4M7U A;  4RGC A;  2BL9 A;  1S3Y A;  3NXX A;  4XE6 X;  3FL9 A;  4KJK A;  2C2S A;  4M7V A;  4X5G A;  3TQB A;  1RX8 A;  1J3I A;  3QLY A;  3FYV X;  2GD9 A;  4ELE A;  5HI6 A;  3CLB A;  4KAK A;  5HT5 A;  4XT8 A;  4PST A;  1DAJ A;  4CD2 A;  6DFR A;  4IXG X;  3ZPC A;  4EJ1 A;  4LAH X;  5HF2 X;  1RA8 A;  1RX1 A;  3F91 A;  4KY4 A;  4QI9 A;  3FRA X;  3SRU X;  3JWK A;  1RB3 A;  1QZF A;  3NZ6 X;  2FZH A;  3NZC X;  3ZPG A;  1OHK A;  3RG9 A;  3FRB X;  1HFQ A;  3DAU A;  3SA2 A;  3QYO A;  3SRW X;  1DYH A;  1VJ3 A;  1IA4 A;  4QLE A;  3OCH A;  1BOZ A;  1RH3 A;  3M09 A;  3SGY A;  2DRC A;  1AOE A;  3F0U X;  3FQF A;  2FZJ A;  5HVB A;  4HOF A;  3KJS A;  1RX6 A;  1DLR A;  4EIZ A;  5HT4 A;  4X5J A;  1DR2 A;  3S9U A;  1RX4 A;  5CC9 A;  2W3A A;  3NZ9 X;  4ELF A;  3K74 A;  3R33 A;  4P68 A;  2HM9 A;  3QLW A;  3Q1H A;  1DHI A;  3EIG A;  3JWC A;  2FZI A;  3ROA A;  3FQC A;  2XW7 A;  1DR5 A;  3DG8 A;  3QLZ A;  4P3R A;  1DRB A;  4KY8 A;  3F8Z A;  2AZN A;  2QK8 A;  1DG7 A;  4P66 A;  3NTZ A;  1HFP A;  4IXE D;  4KYA A;  4X5F A;  4LAG X;  3GHC A;  4EIL A;  1DLS A;  1RE7 A;  4FGH A;  3L3R A;  2HQP A;  3NRR A;  4KNE A;  3DAT A;  3VCO A;  3SAI A;  3OAF A;  4IXF X;  1DF7 A;  3IRO A;  2JYB A;  1VDR A;  3EEK A;  1DDR A;  4M6L A;  4M6K A;  3JSU A;  3QYL A;  4KFJ A;  1AO8 A;  4H96 A;  2B3Z A;  3FRE X;  3F0Q X;  4QLG A;  4XT6 A;  3SRS X;  3INV A;  1DG8 A;  3QLX A;  2W3V A;  3SQY X;  4HA7 A;  3FYW X;  1CZ3 A;  3FY8 X;  3SR5 X;  3DL6 A;  4Q6A A;  3FY9 X;  1J3K A;  3NU0 A;  1M79 A;  4KJJ A;  3NXT A;  3I3R A;  1DR6 A;  4DPD A;  4PSS A;  3QLR A;  2ANO A;  4KD7 A;  4NX6 A;  3QL0 A;  3F0S X;  3KGY A;  1RA9 A;  3GHW A;  3D84 X;  2P4G A;  4GH8 A;  1SEJ A;  2ITH A;  3JWF A;  3QL3 A;  3TQA A;  1IA2 A;  3FQ0 A;  2ZZA A;  4KBN A;  3FL8 A;  3NZD A;  2BLB A;  5CCC A;  2W3W A;  4M6J A;  3TQ8 A;  4HOG A;  2BLA A;  4PTJ A;  1J3J A;  2INQ A;  3F8Y A;  1DR3 A;  2DHF A;  1DDS A;  3NXY A;  3DFR A;  3NXO A;  1S3U A;  4DP3 A;  3KJR A;  1D1G A;  4QHV A;  1DR4 A;  3EEM A;  4ELB A;  1YHO A;  2G6V A;  3UM6 A;  3DGA A;  1MVS A;  4ELH A;  4PTH A;  4KM0 A;  3EEJ A;  3FQZ A;  4Q0D A;  2C2T A;  2HXV A;  3SA1 A;  1RA2 A;  5HSU A;  2CD2 A;  5U26 A;  1DYI A;  3TD8 A;  1KLK A;  4OSG A;  3QLS A;  3DL5 A;  8DFR A;  5JA3 A;  1RX9 A;  1ZDR A;  4KJL A;  2W9G A;  4H98 A;  4FHB A;  1JOM A;  3RO9 A;  3EX8 A;  4QLF A;  4HOE A;  3FRF X;  4QJC A;  5JG0 X;  1M78 A;  1DR1 A;  4X5H A;  4I1N A;  3JTW A;  1DHJ A;  3NZA X;  1OHJ A;  1LY4 A;  2W3B A;  1LY3 A;  2D0K A;  4DFR A;  5DXV A;  5HUI A;  3HJ3 A;  3KFY A;  2O7P A;  3I8A X;  3IRM A;  3IX9 A;  4H97 A;  3K47 A;  5ECX A;  1E26 A;  3UM5 A;  1RA3 A;  4NX7 A;  4LEK X;  3S3V A;  1IA3 A;  4M2X A;  3K45 A;  5HSR A;  1DIU A;  1DR7 A;  3M08 A;  2CIG A;  1RX3 A;  4ELG A;  1HFR A;  3GYF A;  4KL9 A;  4G3M A;  5HF0 X;  1DYR A;  3NXV A;  4KM2 A;  4XRB A;  3IRN A;  1RX5 A;  1RF7 A;  1DIS A;  2W3M A;  4G95 A;  4XT5 A;  4LAE X;  1MVT A;  3IA4 A;  3JW5 A;  3FS6 A;  5ECC A;  3E0B A;  3FRD X;  1DG5 A;  1RC4 A;  4EIG A;  5HPB A;  1RX2 A;  3F0B X;  3QFX A;  1U72 A;  3SRQ X;  3EEL A;  1U71 A;  1S3V A;  2LF1 A;  2D5N A;  4DPH A;  5E8Q A;  4KEB A;  1RA1 A;  4HA9 A;  4Q67 A;  3NZB X;  3KY8 A;  2W9T A;  3QGT A;  5U27 A;  3CSE A;  7DFR A;  4OR7 A;  3SH2 A;  3N0H A;  1M7A A;  2L28 A;  1KMV A;  1AI9 A;  4QJZ D;  3JW3 A;  5FDA A;  4PSY A;  4XT4 A;  1IA1 A;  1TDR A;  3D80 A;  4DDR A;  4H95 A;  3F0X X;  1RD7 A;  2BLC A;  4PDJ A;  1RG7 A;  4KLX A;  1DRA A;  3QG2 A;  3LG4 A;  3JWM A;  1BZF A;  4Q0E A;  1LUD A;  1RB2 A;  3CD2 A;  3JVX A;  1KMS A;  2KGK A;  5DFR A;  3S7A A;  3FQO A;  1CD2 A;  3CL9 A;  5HQZ A;  2W9H A;  3FQV A;  4I13 A;  1DRE A;  1DYJ A;  5EAJ A;  2H2Q A;  1S3W A;  2ANQ A;  4G8Z X;  3SRR X;  3TQ9 A;  2OIP A;  1RX7 A;  2W9S A;  1DRH A;  5HQY A;  3GI2 A;  3NXR A;  4XEC X;  1PDB A;  3UM8 A;  1DHF A;  1PD8 A;  4TU5 X;  3K2H A;  1DRF A;  4X5I A;  4ECK A; 
#chains in the Genus database with same CATH homology
 4FGG A;  3HBB A;  5HVE A;  1PD9 A;  3DRC A;  4XT7 A;  4P3Q A;  2OBC A;  1U70 A;  1JOL A;  1JUV A;  3IA5 A;  3F0V X;  3GHV A;  4M7U A;  4RGC A;  2BL9 A;  1S3Y A;  3NXX A;  4XE6 X;  3FL9 A;  4KJK A;  2C2S A;  4M7V A;  4X5G A;  3TQB A;  1RX8 A;  1J3I A;  3QLY A;  3FYV X;  2GD9 A;  4ELE A;  5HI6 A;  3CLB A;  4KAK A;  5HT5 A;  4XT8 A;  4PST A;  1DAJ A;  4CD2 A;  6DFR A;  4IXG X;  3ZPC A;  4EJ1 A;  4LAH X;  5HF2 X;  1RA8 A;  1RX1 A;  3F91 A;  4KY4 A;  4QI9 A;  3FRA X;  3SRU X;  3JWK A;  1RB3 A;  1QZF A;  3NZ6 X;  2FZH A;  3NZC X;  3ZPG A;  1OHK A;  3RG9 A;  3FRB X;  1HFQ A;  3DAU A;  3SA2 A;  3QYO A;  3SRW X;  1DYH A;  1VJ3 A;  1IA4 A;  4QLE A;  3OCH A;  1BOZ A;  1RH3 A;  3M09 A;  3SGY A;  2DRC A;  1AOE A;  3F0U X;  3FQF A;  2FZJ A;  5HVB A;  4HOF A;  3KJS A;  1RX6 A;  1DLR A;  4EIZ A;  5HT4 A;  4X5J A;  1DR2 A;  3S9U A;  1RX4 A;  5CC9 A;  2W3A A;  3NZ9 X;  4ELF A;  3K74 A;  3R33 A;  4P68 A;  2HM9 A;  3QLW A;  3Q1H A;  1DHI A;  3EIG A;  3JWC A;  2FZI A;  3ROA A;  3FQC A;  2XW7 A;  1DR5 A;  3DG8 A;  3QLZ A;  4P3R A;  1DRB A;  4KY8 A;  3F8Z A;  2AZN A;  2QK8 A;  1DG7 A;  4P66 A;  3NTZ A;  1HFP A;  4IXE D;  4KYA A;  4X5F A;  4LAG X;  3GHC A;  4EIL A;  1DLS A;  1RE7 A;  4FGH A;  3L3R A;  2HQP A;  3NRR A;  4KNE A;  3DAT A;  3VCO A;  3SAI A;  3OAF A;  4IXF X;  1DF7 A;  3IRO A;  2JYB A;  1VDR A;  3EEK A;  1DDR A;  4M6L A;  4M6K A;  3JSU A;  3QYL A;  4KFJ A;  1AO8 A;  4H96 A;  2B3Z A;  3FRE X;  3F0Q X;  4QLG A;  4XT6 A;  3SRS X;  3INV A;  1DG8 A;  3QLX A;  2W3V A;  3SQY X;  4HA7 A;  3FYW X;  1CZ3 A;  3FY8 X;  3SR5 X;  3DL6 A;  4Q6A A;  3FY9 X;  1J3K A;  3NU0 A;  1M79 A;  4KJJ A;  3NXT A;  3I3R A;  1DR6 A;  4DPD A;  4PSS A;  3QLR A;  2ANO A;  4KD7 A;  4NX6 A;  3QL0 A;  3F0S X;  3KGY A;  1RA9 A;  3GHW A;  3D84 X;  2P4G A;  4GH8 A;  1SEJ A;  2ITH A;  3JWF A;  3QL3 A;  3TQA A;  1IA2 A;  3FQ0 A;  2ZZA A;  4KBN A;  3FL8 A;  3NZD A;  2BLB A;  5CCC A;  2W3W A;  4M6J A;  3TQ8 A;  4HOG A;  2BLA A;  4PTJ A;  1J3J A;  2INQ A;  3F8Y A;  1DR3 A;  2DHF A;  1DDS A;  3NXY A;  3DFR A;  3NXO A;  1S3U A;  4DP3 A;  3KJR A;  1D1G A;  4QHV A;  1DR4 A;  3EEM A;  4ELB A;  1YHO A;  2G6V A;  3UM6 A;  3DGA A;  1MVS A;  4ELH A;  4PTH A;  4KM0 A;  3EEJ A;  3FQZ A;  4Q0D A;  2C2T A;  2HXV A;  3SA1 A;  1RA2 A;  5HSU A;  2CD2 A;  5U26 A;  1DYI A;  3TD8 A;  1KLK A;  4OSG A;  3QLS A;  3DL5 A;  8DFR A;  5JA3 A;  1RX9 A;  1ZDR A;  4KJL A;  2W9G A;  4H98 A;  4FHB A;  1JOM A;  3RO9 A;  3EX8 A;  4QLF A;  4HOE A;  3FRF X;  4QJC A;  5JG0 X;  1M78 A;  1DR1 A;  4X5H A;  4I1N A;  3JTW A;  1DHJ A;  3NZA X;  1OHJ A;  1LY4 A;  2W3B A;  1LY3 A;  2D0K A;  4DFR A;  5DXV A;  5HUI A;  3HJ3 A;  3KFY A;  2O7P A;  3I8A X;  3IRM A;  3IX9 A;  4H97 A;  3K47 A;  5ECX A;  1E26 A;  3UM5 A;  1RA3 A;  4NX7 A;  4LEK X;  3S3V A;  1IA3 A;  4M2X A;  3K45 A;  5HSR A;  1DIU A;  1DR7 A;  3M08 A;  2CIG A;  1RX3 A;  4ELG A;  1HFR A;  3GYF A;  4KL9 A;  4G3M A;  5HF0 X;  1DYR A;  3NXV A;  4KM2 A;  4XRB A;  3IRN A;  1RX5 A;  1RF7 A;  1DIS A;  2W3M A;  4G95 A;  4XT5 A;  4LAE X;  1MVT A;  3IA4 A;  3JW5 A;  3FS6 A;  5ECC A;  3E0B A;  3FRD X;  1DG5 A;  1RC4 A;  4EIG A;  5HPB A;  1RX2 A;  3F0B X;  3QFX A;  1U72 A;  3SRQ X;  3EEL A;  1U71 A;  1S3V A;  2LF1 A;  2D5N A;  4DPH A;  5E8Q A;  4KEB A;  1RA1 A;  4HA9 A;  4Q67 A;  3NZB X;  3KY8 A;  2W9T A;  3QGT A;  5U27 A;  3CSE A;  7DFR A;  4OR7 A;  3SH2 A;  3N0H A;  1M7A A;  2L28 A;  1KMV A;  1AI9 A;  4QJZ D;  3JW3 A;  5FDA A;  4PSY A;  4XT4 A;  1IA1 A;  1TDR A;  3D80 A;  4DDR A;  4H95 A;  3F0X X;  1RD7 A;  2BLC A;  4PDJ A;  1RG7 A;  4KLX A;  1DRA A;  3QG2 A;  3LG4 A;  3JWM A;  1BZF A;  4Q0E A;  1LUD A;  1RB2 A;  3CD2 A;  3JVX A;  1KMS A;  2KGK A;  5DFR A;  3S7A A;  3FQO A;  1CD2 A;  3CL9 A;  5HQZ A;  2W9H A;  3FQV A;  4I13 A;  1DRE A;  1DYJ A;  5EAJ A;  2H2Q A;  1S3W A;  2ANQ A;  4G8Z X;  3SRR X;  3TQ9 A;  2OIP A;  1RX7 A;  2W9S A;  1DRH A;  5HQY A;  3GI2 A;  3NXR A;  4XEC X;  1PDB A;  3UM8 A;  1DHF A;  1PD8 A;  4TU5 X;  3K2H A;  1DRF A;  4X5I A;  4ECK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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