1RF8B

Solution structure of the yeast translation initiation factor eif4e in complex with m7gdp and eif4gi residues 393 to 490
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
100
structure length
100
Chain Sequence
GSIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Biosynthetic protein, translation
molecule keywords Eukaryotic translation initiation factor 4E
publication title Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
total genus 12
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2003-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF12152 eIF_4G1 Eukaryotic translation initiation factor 4G1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.30 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 1rf8B01
1RF8B
chains in the Genus database with same CATH superfamily
4YYYA 5BNEA 4LHMA 4OWVA 2ELCA 4XR5A 3QR9A 4OWQA 1UOUA 1VQUA 3GBRA 4X46A 5EP8A 4X5CA 4X59A 1AZYA 3R6CA 4HKMA 2WK5A 5C2LA 1ZYKA 4GA5A 4X5EA 5BO3A 1OTPA 4OWSA 4X5DA 1ZVWA 4ZOFA 2BPQA 2WK6A 1KHDA 1RF8B 3TWPA 4ZOJA 5EY3A 4M0RA 2TPTA 4N5VA 1BRWA 3QS8A 4OWOA 1ZXYA 4F3FC 4X58A 4IJ1A 5BYTA 4X5BA 3QQSA 4N8QA 4GTNA 4YEKA 5C7SA 1O17A 4OWNA 4GA4A 4ZOKA 4GA6A 3QSAA 4GKMA 2DSJA 1RRZA 3H5QA 1GXBA 4EADA 5BO2A 2GVQA 4GIUA 4YI7A 4OWUA 2J0FA 3UU1A 3R88A 5C1RA 4MUOA 1KGZA 1V8GA 4EAFA 4ZTVA 4X5AA 4N93A 4OWMA
chains in the Genus database with same CATH topology
4GA6A 1RF8B 4GA5A 4F3FC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RF8 B; 
#chains in the Genus database with same CATH topology
 4YYY A;  5BNE A;  4LHM A;  4OWV A;  2ELC A;  4XR5 A;  3QR9 A;  4OWQ A;  1UOU A;  1VQU A;  3GBR A;  4X46 A;  5EP8 A;  4X5C A;  4X59 A;  1AZY A;  3R6C A;  4HKM A;  2WK5 A;  5C2L A;  1ZYK A;  4GA5 A;  4X5E A;  5BO3 A;  1OTP A;  4OWS A;  4X5D A;  1ZVW A;  4ZOF A;  2BPQ A;  2WK6 A;  1KHD A;  1RF8 B;  3TWP A;  4ZOJ A;  5EY3 A;  4M0R A;  2TPT A;  4N5V A;  1BRW A;  3QS8 A;  4OWO A;  1ZXY A;  4F3F C;  4X58 A;  4IJ1 A;  5BYT A;  4X5B A;  3QQS A;  4N8Q A;  4GTN A;  4YEK A;  5C7S A;  1O17 A;  4OWN A;  4GA4 A;  4ZOK A;  4GA6 A;  3QSA A;  4GKM A;  2DSJ A;  1RRZ A;  3H5Q A;  1GXB A;  4EAD A;  5BO2 A;  2GVQ A;  4GIU A;  4YI7 A;  4OWU A;  2J0F A;  3UU1 A;  3R88 A;  5C1R A;  4MUO A;  1KGZ A;  1V8G A;  4EAF A;  4ZTV A;  4X5A A;  4N93 A;  4OWM A; 
#chains in the Genus database with same CATH homology
 4GA6 A;  1RF8 B;  4GA5 A;  4F3F C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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