1RF8B

Solution structure of the yeast translation initiation factor eif4e in complex with m7gdp and eif4gi residues 393 to 490
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
100
structure length
100
Chain Sequence
GSIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
pubmed doi rcsb
molecule tags Biosynthetic protein, translation
source organism Saccharomyces cerevisiae
molecule keywords Eukaryotic translation initiation factor 4E
total genus 12
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2003-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF12152 eIF_4G1 Eukaryotic translation initiation factor 4G1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.30 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 1rf8B01
1RF8B
chains in the Genus database with same CATH superfamily
4X5CA 1RF8B 4N8QA 2WK5A 4YI7A 4X5DA 4GA6A 4OWNA 1AZYA 1ZYKA 3QS8A 3TWPA 2GVQA 1KHDA 4EADA 1UOUA 3GBRA 4GTNA 4HKMA 1ZVWA 5C1RA 4X59A 1BRWA 4ZOFA 4OWMA 4EAFA 4LHMA 4XR5A 3QSAA 5BNEA 3QR9A 4GA4A 4ZTVA 4F3FC 1V8GA 2DSJA 4GA5A 2TPTA 4OWOA 4N5VA 5C7SA 5EY3A 1KGZA 1RRZA 4OWQA 4OWUA 2BPQA 1ZXYA 4ZOKA 4ZOJA 4YYYA 4X5AA 4X46A 1O17A 4MUOA 4X5BA 4X58A 4YEKA 4M0RA 5BO3A 5C2LA 4IJ1A 4GIUA 4GKMA 2ELCA 3R88A 1VQUA 3UU1A 4X5EA 4OWSA 3R6CA 2WK6A 5BYTA 4N93A 3QQSA 2J0FA 4OWVA 3H5QA 1OTPA 5BO2A 1GXBA 5EP8A
chains in the Genus database with same CATH topology
4GA6A 1RF8B 4GA5A 4F3FC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RF8 B; 
#chains in the Genus database with same CATH topology
 4X5C A;  1RF8 B;  4N8Q A;  2WK5 A;  4YI7 A;  4X5D A;  4GA6 A;  4OWN A;  1AZY A;  1ZYK A;  3QS8 A;  3TWP A;  2GVQ A;  1KHD A;  4EAD A;  1UOU A;  3GBR A;  4GTN A;  4HKM A;  1ZVW A;  5C1R A;  4X59 A;  1BRW A;  4ZOF A;  4OWM A;  4EAF A;  4LHM A;  4XR5 A;  3QSA A;  5BNE A;  3QR9 A;  4GA4 A;  4ZTV A;  4F3F C;  1V8G A;  2DSJ A;  4GA5 A;  2TPT A;  4OWO A;  4N5V A;  5C7S A;  5EY3 A;  1KGZ A;  1RRZ A;  4OWQ A;  4OWU A;  2BPQ A;  1ZXY A;  4ZOK A;  4ZOJ A;  4YYY A;  4X5A A;  4X46 A;  1O17 A;  4MUO A;  4X5B A;  4X58 A;  4YEK A;  4M0R A;  5BO3 A;  5C2L A;  4IJ1 A;  4GIU A;  4GKM A;  2ELC A;  3R88 A;  1VQU A;  3UU1 A;  4X5E A;  4OWS A;  3R6C A;  2WK6 A;  5BYT A;  4N93 A;  3QQS A;  2J0F A;  4OWV A;  3H5Q A;  1OTP A;  5BO2 A;  1GXB A;  5EP8 A; 
#chains in the Genus database with same CATH homology
 4GA6 A;  1RF8 B;  4GA5 A;  4F3F C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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