1RF8B

Solution structure of the yeast translation initiation factor eif4e in complex with m7gdp and eif4gi residues 393 to 490
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
100
structure length
100
Chain Sequence
GSIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Biosynthetic protein, translation
molecule keywords Eukaryotic translation initiation factor 4E
publication title Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
total genus 12
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2003-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF12152 eIF_4G1 Eukaryotic translation initiation factor 4G1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.30 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 1rf8B01
1RF8B
chains in the Genus database with same CATH superfamily
4OWMA 3GBRA 5C1RA 2J0FA 1V8GA 3QR9A 3H5QA 3R6CA 5BO3A 2GVQA 4X5DA 4N5VA 1RRZA 1KHDA 4GKMA 4EAFA 3UU1A 4X46A 4OWSA 4N8QA 3R88A 1VQUA 4X5CA 4OWNA 4LHMA 2WK6A 4F3FC 4ZTVA 5C7SA 4IJ1A 4YI7A 2ELCA 2TPTA 4GA6A 1ZVWA 4OWVA 1O17A 3TWPA 4X59A 1GXBA 4MUOA 4GTNA 1OTPA 1UOUA 4N93A 4M0RA 4GA5A 1AZYA 2BPQA 5EP8A 5C2LA 3QQSA 4XR5A 4EADA 4ZOFA 1ZXYA 5BO2A 4ZOJA 4ZOKA 1RF8B 5EY3A 5BNEA 5BYTA 4X5EA 2DSJA 4OWQA 1BRWA 3QS8A 4YYYA 4GA4A 1ZYKA 4HKMA 3QSAA 4X5AA 4X5BA 4OWUA 4X58A 4GIUA 2WK5A 4YEKA 1KGZA 4OWOA
chains in the Genus database with same CATH topology
1RF8B 4GA6A 4F3FC 4GA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RF8 B; 
#chains in the Genus database with same CATH topology
 4OWM A;  3GBR A;  5C1R A;  2J0F A;  1V8G A;  3QR9 A;  3H5Q A;  3R6C A;  5BO3 A;  2GVQ A;  4X5D A;  4N5V A;  1RRZ A;  1KHD A;  4GKM A;  4EAF A;  3UU1 A;  4X46 A;  4OWS A;  4N8Q A;  3R88 A;  1VQU A;  4X5C A;  4OWN A;  4LHM A;  2WK6 A;  4F3F C;  4ZTV A;  5C7S A;  4IJ1 A;  4YI7 A;  2ELC A;  2TPT A;  4GA6 A;  1ZVW A;  4OWV A;  1O17 A;  3TWP A;  4X59 A;  1GXB A;  4MUO A;  4GTN A;  1OTP A;  1UOU A;  4N93 A;  4M0R A;  4GA5 A;  1AZY A;  2BPQ A;  5EP8 A;  5C2L A;  3QQS A;  4XR5 A;  4EAD A;  4ZOF A;  1ZXY A;  5BO2 A;  4ZOJ A;  4ZOK A;  1RF8 B;  5EY3 A;  5BNE A;  5BYT A;  4X5E A;  2DSJ A;  4OWQ A;  1BRW A;  3QS8 A;  4YYY A;  4GA4 A;  1ZYK A;  4HKM A;  3QSA A;  4X5A A;  4X5B A;  4OWU A;  4X58 A;  4GIU A;  2WK5 A;  4YEK A;  1KGZ A;  4OWO A; 
#chains in the Genus database with same CATH homology
 1RF8 B;  4GA6 A;  4F3F C;  4GA5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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