1RXMA

C-terminal region of fen-1 bound to a. fulgidus pcna
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
245
structure length
245
Chain Sequence
MIDVIMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVKFGSVEYKVALIDPSAIRKEPRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMTETELIEFNGGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELVGGRAKVEYILAPRIESE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
pubmed doi rcsb
molecule keywords DNA polymerase sliding clamp
molecule tags Replication
source organism Archaeoglobus fulgidus
total genus 62
structure length 245
sequence length 245
ec nomenclature
pdb deposition date 2003-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1rxmA00
2HIIB 1B77A 3WGWA 3GPNA 2NTIA 1UD9A 1CZDA 2ZVVA 3G65B 3FDSD 3GGRB 2IZOB 3AIZC 2IZOC 1AXCA 5E0UA 2AVTA 1PLRA 5CFKA 1VYMA 3V60B 5B7OA 3AIXA 1RXMA 5A6DA 3A1JA 1GE8A 2OD8A 4HK1A 3GPMA 4CS5A 2NTIC 3U5ZF 2ZVKA 2ZVMA 2IX2A 4D2GA 1ISQA 1RXZA 1IZ4A 3A2FB 5E0VA 1YYPA 3VKXA 3FDSC 3P87A 2HIKA 2HIIA 4YHRA 5IY4A 2Z0LA 4RJFA 1IZ5A 1W60A 4TR6A 2IO4B 3G65A 3P91A 3GGRA 3A1JC 3I2MX 2NTIB 3LX1A 5IWDA 2IJXA 2ZVWA 5DAIA 2AWAA 1RWZA 1DMLA 3V62B 3U60F 1UL1A 3P83A 4L6PA 5DA7A 1PLQA 4ZTDA 1U7BA 3LX2A 3TBLA 2HIKC 2ZVLA 2HIIC 5H0TA 3F1WA 3HSLX 3K4XA 3AIXB 3G65C 3A1JB 5IXAA 3AIZA 5HACA 1VYJA 3GGRC 5E0TA 3IFVA 5JNED 3U61F 3HI8A 4L60A 2IX2B 2IX2C 1U76A 3V61B 1T6LA 5AUJA 1B8HA 2IO4A 1SXJF 2HIKB
chains in the Genus database with same CATH superfamily
2HIIB 1B77A 3WGWA 3GPNA 2NTIA 1UD9A 1CZDA 2ZVVA 3G65B 3FDSD 3GGRB 2IZOB 3AIZC 2IZOC 1AXCA 5E0UA 2AVTA 1PLRA 5CFKA 1VYMA 3V60B 5B7OA 3AIXA 1RXMA 5A6DA 3A1JA 1GE8A 2OD8A 4HK1A 3GPMA 4CS5A 2NTIC 3U5ZF 2ZVKA 2ZVMA 2IX2A 4D2GA 1ISQA 1RXZA 1IZ4A 3A2FB 5E0VA 1YYPA 3VKXA 3FDSC 3P87A 2HIKA 2HIIA 4YHRA 5IY4A 2Z0LA 4RJFA 1IZ5A 1W60A 4TR6A 2IO4B 3G65A 3P91A 3GGRA 3A1JC 3I2MX 2NTIB 3LX1A 5IWDA 2IJXA 2ZVWA 5DAIA 2AWAA 1RWZA 1DMLA 3V62B 3U60F 1UL1A 3P83A 4L6PA 5DA7A 1PLQA 4ZTDA 1U7BA 3LX2A 3TBLA 2HIKC 2ZVLA 2HIIC 5H0TA 3F1WA 3HSLX 3K4XA 3AIXB 3G65C 3A1JB 5IXAA 3AIZA 5HACA 1VYJA 3GGRC 5E0TA 3IFVA 5JNED 3U61F 3HI8A 4L60A 2IX2B 2IX2C 1U76A 3V61B 1T6LA 5AUJA 1B8HA 2IO4A 1SXJF 2HIKB
chains in the Genus database with same CATH topology
2HIIB 1B77A 3WGWA 3GPNA 2NTIA 1UD9A 1CZDA 2ZVVA 3G65B 3FDSD 3GGRB 2IZOB 3AIZC 2IZOC 1AXCA 5E0UA 2AVTA 1PLRA 5CFKA 1VYMA 3V60B 5B7OA 3AIXA 1RXMA 5A6DA 3A1JA 1GE8A 2OD8A 4HK1A 3GPMA 4CS5A 2NTIC 3U5ZF 2ZVKA 2ZVMA 2IX2A 4D2GA 1ISQA 1RXZA 1IZ4A 3A2FB 5E0VA 1YYPA 3VKXA 3FDSC 3P87A 2HIKA 2HIIA 4YHRA 5IY4A 2Z0LA 4RJFA 1IZ5A 1W60A 4TR6A 2IO4B 3G65A 3P91A 3GGRA 3A1JC 3I2MX 2NTIB 3LX1A 5IWDA 2IJXA 2ZVWA 5DAIA 2AWAA 1RWZA 1DMLA 3V62B 3U60F 1UL1A 3P83A 4L6PA 5DA7A 1PLQA 4ZTDA 1U7BA 3LX2A 3TBLA 2HIKC 2ZVLA 2HIIC 5H0TA 3F1WA 3HSLX 3K4XA 3AIXB 3G65C 3A1JB 5IXAA 3AIZA 5HACA 1VYJA 3GGRC 5E0TA 3IFVA 5JNED 3U61F 3HI8A 4L60A 2IX2B 2IX2C 1U76A 3V61B 1T6LA 5AUJA 1B8HA 2IO4A 1SXJF 2HIKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HII B;  1B77 A;  3WGW A;  3GPN A;  2NTI A;  1UD9 A;  1CZD A;  2ZVV A;  3G65 B;  3FDS D;  3GGR B;  2IZO B;  3AIZ C;  2IZO C;  1AXC A;  5E0U A;  2AVT A;  1PLR A;  5CFK A;  1VYM A;  3V60 B;  5B7O A;  3AIX A;  1RXM A;  5A6D A;  3A1J A;  1GE8 A;  2OD8 A;  4HK1 A;  3GPM A;  4CS5 A;  2NTI C;  3U5Z F;  2ZVK A;  2ZVM A;  2IX2 A;  4D2G A;  1ISQ A;  1RXZ A;  1IZ4 A;  3A2F B;  5E0V A;  1YYP A;  3VKX A;  3FDS C;  3P87 A;  2HIK A;  2HII A;  4YHR A;  5IY4 A;  2Z0L A;  4RJF A;  1IZ5 A;  1W60 A;  4TR6 A;  2IO4 B;  3G65 A;  3P91 A;  3GGR A;  3A1J C;  3I2M X;  2NTI B;  3LX1 A;  5IWD A;  2IJX A;  2ZVW A;  5DAI A;  2AWA A;  1RWZ A;  1DML A;  3V62 B;  3U60 F;  1UL1 A;  3P83 A;  4L6P A;  5DA7 A;  1PLQ A;  4ZTD A;  1U7B A;  3LX2 A;  3TBL A;  2HIK C;  2ZVL A;  2HII C;  5H0T A;  3F1W A;  3HSL X;  3K4X A;  3AIX B;  3G65 C;  3A1J B;  5IXA A;  3AIZ A;  5HAC A;  1VYJ A;  3GGR C;  5E0T A;  3IFV A;  5JNE D;  3U61 F;  3HI8 A;  4L60 A;  2IX2 B;  2IX2 C;  1U76 A;  3V61 B;  1T6L A;  5AUJ A;  1B8H A;  2IO4 A;  1SXJ F;  2HIK B; 
#chains in the Genus database with same CATH topology
 2HII B;  1B77 A;  3WGW A;  3GPN A;  2NTI A;  1UD9 A;  1CZD A;  2ZVV A;  3G65 B;  3FDS D;  3GGR B;  2IZO B;  3AIZ C;  2IZO C;  1AXC A;  5E0U A;  2AVT A;  1PLR A;  5CFK A;  1VYM A;  3V60 B;  5B7O A;  3AIX A;  1RXM A;  5A6D A;  3A1J A;  1GE8 A;  2OD8 A;  4HK1 A;  3GPM A;  4CS5 A;  2NTI C;  3U5Z F;  2ZVK A;  2ZVM A;  2IX2 A;  4D2G A;  1ISQ A;  1RXZ A;  1IZ4 A;  3A2F B;  5E0V A;  1YYP A;  3VKX A;  3FDS C;  3P87 A;  2HIK A;  2HII A;  4YHR A;  5IY4 A;  2Z0L A;  4RJF A;  1IZ5 A;  1W60 A;  4TR6 A;  2IO4 B;  3G65 A;  3P91 A;  3GGR A;  3A1J C;  3I2M X;  2NTI B;  3LX1 A;  5IWD A;  2IJX A;  2ZVW A;  5DAI A;  2AWA A;  1RWZ A;  1DML A;  3V62 B;  3U60 F;  1UL1 A;  3P83 A;  4L6P A;  5DA7 A;  1PLQ A;  4ZTD A;  1U7B A;  3LX2 A;  3TBL A;  2HIK C;  2ZVL A;  2HII C;  5H0T A;  3F1W A;  3HSL X;  3K4X A;  3AIX B;  3G65 C;  3A1J B;  5IXA A;  3AIZ A;  5HAC A;  1VYJ A;  3GGR C;  5E0T A;  3IFV A;  5JNE D;  3U61 F;  3HI8 A;  4L60 A;  2IX2 B;  2IX2 C;  1U76 A;  3V61 B;  1T6L A;  5AUJ A;  1B8H A;  2IO4 A;  1SXJ F;  2HIK B; 
#chains in the Genus database with same CATH homology
 2HII B;  1B77 A;  3WGW A;  3GPN A;  2NTI A;  1UD9 A;  1CZD A;  2ZVV A;  3G65 B;  3FDS D;  3GGR B;  2IZO B;  3AIZ C;  2IZO C;  1AXC A;  5E0U A;  2AVT A;  1PLR A;  5CFK A;  1VYM A;  3V60 B;  5B7O A;  3AIX A;  1RXM A;  5A6D A;  3A1J A;  1GE8 A;  2OD8 A;  4HK1 A;  3GPM A;  4CS5 A;  2NTI C;  3U5Z F;  2ZVK A;  2ZVM A;  2IX2 A;  4D2G A;  1ISQ A;  1RXZ A;  1IZ4 A;  3A2F B;  5E0V A;  1YYP A;  3VKX A;  3FDS C;  3P87 A;  2HIK A;  2HII A;  4YHR A;  5IY4 A;  2Z0L A;  4RJF A;  1IZ5 A;  1W60 A;  4TR6 A;  2IO4 B;  3G65 A;  3P91 A;  3GGR A;  3A1J C;  3I2M X;  2NTI B;  3LX1 A;  5IWD A;  2IJX A;  2ZVW A;  5DAI A;  2AWA A;  1RWZ A;  1DML A;  3V62 B;  3U60 F;  1UL1 A;  3P83 A;  4L6P A;  5DA7 A;  1PLQ A;  4ZTD A;  1U7B A;  3LX2 A;  3TBL A;  2HIK C;  2ZVL A;  2HII C;  5H0T A;  3F1W A;  3HSL X;  3K4X A;  3AIX B;  3G65 C;  3A1J B;  5IXA A;  3AIZ A;  5HAC A;  1VYJ A;  3GGR C;  5E0T A;  3IFV A;  5JNE D;  3U61 F;  3HI8 A;  4L60 A;  2IX2 B;  2IX2 C;  1U76 A;  3V61 B;  1T6L A;  5AUJ A;  1B8H A;  2IO4 A;  1SXJ F;  2HIK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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