1RXZA

C-terminal region of a. fulgidus fen-1 complexed with a. fulgidus pcna
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
245
structure length
245
Chain Sequence
MIDVIMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVKFGSVEYKVALIDPSAIRKEPRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMTETELIEFNGGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELVGGRAKVEYILAPRIESE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
pubmed doi rcsb
molecule keywords DNA polymerase sliding clamp
molecule tags Replication
source organism Archaeoglobus fulgidus
total genus 56
structure length 245
sequence length 245
ec nomenclature
pdb deposition date 2003-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1rxzA00
2ZVWA 2ZVKA 1SXJF 5A6DA 5CFKA 2IX2A 1UL1A 2HIKA 3A1JB 3FDSD 4CS5A 3P87A 2IO4B 4RJFA 2AVTA 2HIIB 3HSLX 5DAIA 1RXZA 2IX2C 3VKXA 5AUJA 2ZVVA 2HIKC 4L6PA 2ZVMA 3U61F 2NTIB 3P83A 3IFVA 4YHRA 1CZDA 3GPMA 1UD9A 3LX2A 3FDSC 4D2GA 1IZ4A 2AWAA 1B77A 1B8HA 3AIXB 3G65A 5E0UA 3AIZA 5IXAA 3GGRC 3U60F 5DA7A 3WGWA 2IZOC 2ZVLA 3U5ZF 1GE8A 1VYJA 3GGRA 3P91A 3G65C 3AIZC 3A2FB 2IX2B 1AXCA 2HIKB 2IJXA 5H0TA 4HK1A 2IO4A 5B7OA 1RWZA 2HIIA 4ZTDA 3F1WA 1VYMA 5HACA 1U76A 3A1JC 1U7BA 3GPNA 3K4XA 1YYPA 1W60A 3LX1A 5JNED 2NTIA 3V62B 1IZ5A 5IWDA 3V60B 1PLRA 2HIIC 3HI8A 3TBLA 5IY4A 1PLQA 3A1JA 3I2MX 3GGRB 4L60A 1RXMA 4TR6A 2Z0LA 5E0TA 2IZOB 3AIXA 2NTIC 5E0VA 1DMLA 1T6LA 2OD8A 1ISQA 3V61B 3G65B
chains in the Genus database with same CATH superfamily
2ZVWA 2ZVKA 1SXJF 5A6DA 5CFKA 2IX2A 1UL1A 2HIKA 3A1JB 3FDSD 4CS5A 3P87A 2IO4B 4RJFA 2AVTA 2HIIB 3HSLX 5DAIA 1RXZA 2IX2C 3VKXA 5AUJA 2ZVVA 2HIKC 4L6PA 2ZVMA 3U61F 2NTIB 3P83A 3IFVA 4YHRA 1CZDA 3GPMA 1UD9A 3LX2A 3FDSC 4D2GA 1IZ4A 2AWAA 1B77A 1B8HA 3AIXB 3G65A 5E0UA 3AIZA 5IXAA 3GGRC 3U60F 5DA7A 3WGWA 2IZOC 2ZVLA 3U5ZF 1GE8A 1VYJA 3GGRA 3P91A 3G65C 3AIZC 3A2FB 2IX2B 1AXCA 2HIKB 2IJXA 5H0TA 4HK1A 2IO4A 5B7OA 1RWZA 2HIIA 4ZTDA 3F1WA 1VYMA 5HACA 1U76A 3A1JC 1U7BA 3GPNA 3K4XA 1YYPA 1W60A 3LX1A 5JNED 2NTIA 3V62B 1IZ5A 5IWDA 3V60B 1PLRA 2HIIC 3HI8A 3TBLA 5IY4A 1PLQA 3A1JA 3I2MX 3GGRB 4L60A 1RXMA 4TR6A 2Z0LA 5E0TA 2IZOB 3AIXA 2NTIC 5E0VA 1DMLA 1T6LA 2OD8A 1ISQA 3V61B 3G65B
chains in the Genus database with same CATH topology
2ZVWA 2ZVKA 1SXJF 5A6DA 5CFKA 2IX2A 1UL1A 2HIKA 3A1JB 3FDSD 4CS5A 3P87A 2IO4B 4RJFA 2AVTA 2HIIB 3HSLX 5DAIA 1RXZA 2IX2C 3VKXA 5AUJA 2ZVVA 2HIKC 4L6PA 2ZVMA 3U61F 2NTIB 3P83A 3IFVA 4YHRA 1CZDA 3GPMA 1UD9A 3LX2A 3FDSC 4D2GA 1IZ4A 2AWAA 1B77A 1B8HA 3AIXB 3G65A 5E0UA 3AIZA 5IXAA 3GGRC 3U60F 5DA7A 3WGWA 2IZOC 2ZVLA 3U5ZF 1GE8A 1VYJA 3GGRA 3P91A 3G65C 3AIZC 3A2FB 2IX2B 1AXCA 2HIKB 2IJXA 5H0TA 4HK1A 2IO4A 5B7OA 1RWZA 2HIIA 4ZTDA 3F1WA 1VYMA 5HACA 1U76A 3A1JC 1U7BA 3GPNA 3K4XA 1YYPA 1W60A 3LX1A 5JNED 2NTIA 3V62B 1IZ5A 5IWDA 3V60B 1PLRA 2HIIC 3HI8A 3TBLA 5IY4A 1PLQA 3A1JA 3I2MX 3GGRB 4L60A 1RXMA 4TR6A 2Z0LA 5E0TA 2IZOB 3AIXA 2NTIC 5E0VA 1DMLA 1T6LA 2OD8A 1ISQA 3V61B 3G65B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZVW A;  2ZVK A;  1SXJ F;  5A6D A;  5CFK A;  2IX2 A;  1UL1 A;  2HIK A;  3A1J B;  3FDS D;  4CS5 A;  3P87 A;  2IO4 B;  4RJF A;  2AVT A;  2HII B;  3HSL X;  5DAI A;  1RXZ A;  2IX2 C;  3VKX A;  5AUJ A;  2ZVV A;  2HIK C;  4L6P A;  2ZVM A;  3U61 F;  2NTI B;  3P83 A;  3IFV A;  4YHR A;  1CZD A;  3GPM A;  1UD9 A;  3LX2 A;  3FDS C;  4D2G A;  1IZ4 A;  2AWA A;  1B77 A;  1B8H A;  3AIX B;  3G65 A;  5E0U A;  3AIZ A;  5IXA A;  3GGR C;  3U60 F;  5DA7 A;  3WGW A;  2IZO C;  2ZVL A;  3U5Z F;  1GE8 A;  1VYJ A;  3GGR A;  3P91 A;  3G65 C;  3AIZ C;  3A2F B;  2IX2 B;  1AXC A;  2HIK B;  2IJX A;  5H0T A;  4HK1 A;  2IO4 A;  5B7O A;  1RWZ A;  2HII A;  4ZTD A;  3F1W A;  1VYM A;  5HAC A;  1U76 A;  3A1J C;  1U7B A;  3GPN A;  3K4X A;  1YYP A;  1W60 A;  3LX1 A;  5JNE D;  2NTI A;  3V62 B;  1IZ5 A;  5IWD A;  3V60 B;  1PLR A;  2HII C;  3HI8 A;  3TBL A;  5IY4 A;  1PLQ A;  3A1J A;  3I2M X;  3GGR B;  4L60 A;  1RXM A;  4TR6 A;  2Z0L A;  5E0T A;  2IZO B;  3AIX A;  2NTI C;  5E0V A;  1DML A;  1T6L A;  2OD8 A;  1ISQ A;  3V61 B;  3G65 B; 
#chains in the Genus database with same CATH topology
 2ZVW A;  2ZVK A;  1SXJ F;  5A6D A;  5CFK A;  2IX2 A;  1UL1 A;  2HIK A;  3A1J B;  3FDS D;  4CS5 A;  3P87 A;  2IO4 B;  4RJF A;  2AVT A;  2HII B;  3HSL X;  5DAI A;  1RXZ A;  2IX2 C;  3VKX A;  5AUJ A;  2ZVV A;  2HIK C;  4L6P A;  2ZVM A;  3U61 F;  2NTI B;  3P83 A;  3IFV A;  4YHR A;  1CZD A;  3GPM A;  1UD9 A;  3LX2 A;  3FDS C;  4D2G A;  1IZ4 A;  2AWA A;  1B77 A;  1B8H A;  3AIX B;  3G65 A;  5E0U A;  3AIZ A;  5IXA A;  3GGR C;  3U60 F;  5DA7 A;  3WGW A;  2IZO C;  2ZVL A;  3U5Z F;  1GE8 A;  1VYJ A;  3GGR A;  3P91 A;  3G65 C;  3AIZ C;  3A2F B;  2IX2 B;  1AXC A;  2HIK B;  2IJX A;  5H0T A;  4HK1 A;  2IO4 A;  5B7O A;  1RWZ A;  2HII A;  4ZTD A;  3F1W A;  1VYM A;  5HAC A;  1U76 A;  3A1J C;  1U7B A;  3GPN A;  3K4X A;  1YYP A;  1W60 A;  3LX1 A;  5JNE D;  2NTI A;  3V62 B;  1IZ5 A;  5IWD A;  3V60 B;  1PLR A;  2HII C;  3HI8 A;  3TBL A;  5IY4 A;  1PLQ A;  3A1J A;  3I2M X;  3GGR B;  4L60 A;  1RXM A;  4TR6 A;  2Z0L A;  5E0T A;  2IZO B;  3AIX A;  2NTI C;  5E0V A;  1DML A;  1T6L A;  2OD8 A;  1ISQ A;  3V61 B;  3G65 B; 
#chains in the Genus database with same CATH homology
 2ZVW A;  2ZVK A;  1SXJ F;  5A6D A;  5CFK A;  2IX2 A;  1UL1 A;  2HIK A;  3A1J B;  3FDS D;  4CS5 A;  3P87 A;  2IO4 B;  4RJF A;  2AVT A;  2HII B;  3HSL X;  5DAI A;  1RXZ A;  2IX2 C;  3VKX A;  5AUJ A;  2ZVV A;  2HIK C;  4L6P A;  2ZVM A;  3U61 F;  2NTI B;  3P83 A;  3IFV A;  4YHR A;  1CZD A;  3GPM A;  1UD9 A;  3LX2 A;  3FDS C;  4D2G A;  1IZ4 A;  2AWA A;  1B77 A;  1B8H A;  3AIX B;  3G65 A;  5E0U A;  3AIZ A;  5IXA A;  3GGR C;  3U60 F;  5DA7 A;  3WGW A;  2IZO C;  2ZVL A;  3U5Z F;  1GE8 A;  1VYJ A;  3GGR A;  3P91 A;  3G65 C;  3AIZ C;  3A2F B;  2IX2 B;  1AXC A;  2HIK B;  2IJX A;  5H0T A;  4HK1 A;  2IO4 A;  5B7O A;  1RWZ A;  2HII A;  4ZTD A;  3F1W A;  1VYM A;  5HAC A;  1U76 A;  3A1J C;  1U7B A;  3GPN A;  3K4X A;  1YYP A;  1W60 A;  3LX1 A;  5JNE D;  2NTI A;  3V62 B;  1IZ5 A;  5IWD A;  3V60 B;  1PLR A;  2HII C;  3HI8 A;  3TBL A;  5IY4 A;  1PLQ A;  3A1J A;  3I2M X;  3GGR B;  4L60 A;  1RXM A;  4TR6 A;  2Z0L A;  5E0T A;  2IZO B;  3AIX A;  2NTI C;  5E0V A;  1DML A;  1T6L A;  2OD8 A;  1ISQ A;  3V61 B;  3G65 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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