1S13A

Human heme oxygenase oxidatition of alpha- and gamma-meso-phenylhemes
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
214
structure length
214
Chain Sequence
PQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Heme oxygenase 1
publication title Human heme oxygenase oxidation of 5- and 15-phenylhemes.
pubmed doi rcsb
source organism Homo sapiens
total genus 78
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2004-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 1s13A00
1OZEA 1S8CA 2A2MA 1WZGA 1V8XA 3HMLA 4LQXA 4FN6A 1RTWA 2QZCA 2A2OA 3B5PA 4WD4A 3MOOA 3K4FA 3DDEA 1WOVA 2ZVUA 2GM7A 4WWJA 1TO9B 4RAJA 1P3TA 3HLXA 1IW1A 1XJZA 2QCXA 1N3UA 2GM8A 1P3UA 3NO6A 3RM5A 3CZYA 1TO9A 1YAKA 3HOKA 4GPFA 3IBXA 1DVGA 1N45A 4G99A 2Q4XA 1WZDA 1IX3A 4WX0A 3OQLA 2Z68A 1XK2A 4GPHA 2DY5A 1IW0A 1T5PA 1IVJA 3I9TA 1OYKA 1TWRA 1WZFA 1OYLA 1OTWA 1SK7A 1OZRA 1WOWA 4G7UA 2RGZA 4MECA 1S13A 4G7TA 4G7LA 1OZLA 3BJDA 4GPCA 1TYHA 1WE1A 1XK1A 4G8WA 1XK0A 1IRMA 1XK3A 1IX4A 5BTQA 3TGMA 1UDDA 4NY7A 1NI6A 4G98A 1VGIA 1J2CA 3HNHA 4G7PA 1OZWA 2Q32A 1DVEA 2RD3A 1Z72A 2QPPA 2F2GA 4GOHA 1P3VA 1TWNA 3I8RA 1WOXA 1J77A 4WMHA 1ULXA 1OTVA 1WNWA 3I9UA 2A6BA 3MVUA 4G8UA 4WWZA 1YAFA 1J02A 1WWMA 1WNVA 1UBBA 1RCWA 3B5OA 1WNXA 4G8PA 2E7EA
chains in the Genus database with same CATH superfamily
1OZEA 1S8CA 2A2MA 1WZGA 1V8XA 3HMLA 4LQXA 4FN6A 1RTWA 2QZCA 2A2OA 3B5PA 4WD4A 3MOOA 3K4FA 3DDEA 1WOVA 2ZVUA 2GM7A 4WWJA 1TO9B 4RAJA 1P3TA 3HLXA 1IW1A 1XJZA 2QCXA 2LCUA 1N3UA 2GM8A 1P3UA 3NO6A 3RM5A 3CZYA 1TO9A 1YAKA 3HOKA 4GPFA 3IBXA 1DVGA 1N45A 4G99A 2Q4XA 1WZDA 1IX3A 4WX0A 3OQLA 2Z68A 1XK2A 4GPHA 2DY5A 1IW0A 1T5PA 1IVJA 3I9TA 1OYKA 1TWRA 1WZFA 1OYLA 1OTWA 1SK7A 1OZRA 1WOWA 4G7UA 2RGZA 4MECA 1S13A 4G7TA 4G7LA 1OZLA 3BJDA 4GPCA 1TYHA 1WE1A 1XK1A 4G8WA 1XK0A 1IRMA 1XK3A 1IX4A 5BTQA 3TGMA 1UDDA 4NY7A 1NI6A 4G98A 1VGIA 1J2CA 3HNHA 4G7PA 1OZWA 2Q32A 1DVEA 2RD3A 1Z72A 2QPPA 2F2GA 4GOHA 1P3VA 1TWNA 3I8RA 1WOXA 1J77A 4WMHA 1ULXA 1OTVA 1WNWA 3I9UA 2A6BA 3MVUA 4G8UA 4WWZA 1YAFA 1J02A 1WWMA 1WNVA 1UBBA 1RCWA 3B5OA 1WNXA 4G8PA 2E7EA
chains in the Genus database with same CATH topology
1OZEA 1S8CA 2A2MA 1WZGA 1V8XA 3HMLA 4LQXA 4FN6A 1RTWA 2QZCA 2A2OA 3B5PA 4WD4A 3MOOA 3K4FA 3DDEA 1WOVA 2ZVUA 2GM7A 4WWJA 1TO9B 4RAJA 1P3TA 3HLXA 1IW1A 1XJZA 2QCXA 1N3UA 2GM8A 1P3UA 3NO6A 3RM5A 3CZYA 1TO9A 1YAKA 3HOKA 4GPFA 3IBXA 1DVGA 1N45A 4G99A 2Q4XA 1WZDA 1IX3A 4WX0A 3OQLA 2Z68A 1XK2A 4GPHA 2DY5A 1IW0A 1T5PA 1IVJA 3I9TA 1OYKA 1TWRA 1WZFA 1OYLA 1OTWA 1SK7A 1OZRA 1WOWA 4G7UA 2RGZA 4MECA 1S13A 4G7TA 4G7LA 1OZLA 3BJDA 4GPCA 1TYHA 1WE1A 1XK1A 4G8WA 1XK0A 1IRMA 1XK3A 1IX4A 5BTQA 3TGMA 1UDDA 4NY7A 1NI6A 4G98A 1VGIA 1J2CA 3HNHA 4G7PA 1OZWA 2Q32A 1DVEA 2RD3A 1Z72A 2QPPA 2F2GA 4GOHA 1P3VA 1TWNA 3I8RA 1WOXA 1J77A 4WMHA 1ULXA 1OTVA 1WNWA 3I9UA 2A6BA 3MVUA 4G8UA 4WWZA 1YAFA 1J02A 1WWMA 1WNVA 1UBBA 1RCWA 3B5OA 1WNXA 4G8PA 2E7EA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1OZE A;  1S8C A;  2A2M A;  1WZG A;  1V8X A;  3HML A;  4LQX A;  4FN6 A;  1RTW A;  2QZC A;  2A2O A;  3B5P A;  4WD4 A;  3MOO A;  3K4F A;  3DDE A;  1WOV A;  2ZVU A;  2GM7 A;  4WWJ A;  1TO9 B;  4RAJ A;  1P3T A;  3HLX A;  1IW1 A;  1XJZ A;  2QCX A;  1N3U A;  2GM8 A;  1P3U A;  3NO6 A;  3RM5 A;  3CZY A;  1TO9 A;  1YAK A;  3HOK A;  4GPF A;  3IBX A;  1DVG A;  1N45 A;  4G99 A;  2Q4X A;  1WZD A;  1IX3 A;  4WX0 A;  3OQL A;  2Z68 A;  1XK2 A;  4GPH A;  2DY5 A;  1IW0 A;  1T5P A;  1IVJ A;  3I9T A;  1OYK A;  1TWR A;  1WZF A;  1OYL A;  1OTW A;  1SK7 A;  1OZR A;  1WOW A;  4G7U A;  2RGZ A;  4MEC A;  1S13 A;  4G7T A;  4G7L A;  1OZL A;  3BJD A;  4GPC A;  1TYH A;  1WE1 A;  1XK1 A;  4G8W A;  1XK0 A;  1IRM A;  1XK3 A;  1IX4 A;  5BTQ A;  3TGM A;  1UDD A;  4NY7 A;  1NI6 A;  4G98 A;  1VGI A;  1J2C A;  3HNH A;  4G7P A;  1OZW A;  2Q32 A;  1DVE A;  2RD3 A;  1Z72 A;  2QPP A;  2F2G A;  4GOH A;  1P3V A;  1TWN A;  3I8R A;  1WOX A;  1J77 A;  4WMH A;  1ULX A;  1OTV A;  1WNW A;  3I9U A;  2A6B A;  3MVU A;  4G8U A;  4WWZ A;  1YAF A;  1J02 A;  1WWM A;  1WNV A;  1UBB A;  1RCW A;  3B5O A;  1WNX A;  4G8P A;  2E7E A; 
#chains in the Genus database with same CATH topology
 1OZE A;  1S8C A;  2A2M A;  1WZG A;  1V8X A;  3HML A;  4LQX A;  4FN6 A;  1RTW A;  2QZC A;  2A2O A;  3B5P A;  4WD4 A;  3MOO A;  3K4F A;  3DDE A;  1WOV A;  2ZVU A;  2GM7 A;  4WWJ A;  1TO9 B;  4RAJ A;  1P3T A;  3HLX A;  1IW1 A;  1XJZ A;  2QCX A;  2LCU A;  1N3U A;  2GM8 A;  1P3U A;  3NO6 A;  3RM5 A;  3CZY A;  1TO9 A;  1YAK A;  3HOK A;  4GPF A;  3IBX A;  1DVG A;  1N45 A;  4G99 A;  2Q4X A;  1WZD A;  1IX3 A;  4WX0 A;  3OQL A;  2Z68 A;  1XK2 A;  4GPH A;  2DY5 A;  1IW0 A;  1T5P A;  1IVJ A;  3I9T A;  1OYK A;  1TWR A;  1WZF A;  1OYL A;  1OTW A;  1SK7 A;  1OZR A;  1WOW A;  4G7U A;  2RGZ A;  4MEC A;  1S13 A;  4G7T A;  4G7L A;  1OZL A;  3BJD A;  4GPC A;  1TYH A;  1WE1 A;  1XK1 A;  4G8W A;  1XK0 A;  1IRM A;  1XK3 A;  1IX4 A;  5BTQ A;  3TGM A;  1UDD A;  4NY7 A;  1NI6 A;  4G98 A;  1VGI A;  1J2C A;  3HNH A;  4G7P A;  1OZW A;  2Q32 A;  1DVE A;  2RD3 A;  1Z72 A;  2QPP A;  2F2G A;  4GOH A;  1P3V A;  1TWN A;  3I8R A;  1WOX A;  1J77 A;  4WMH A;  1ULX A;  1OTV A;  1WNW A;  3I9U A;  2A6B A;  3MVU A;  4G8U A;  4WWZ A;  1YAF A;  1J02 A;  1WWM A;  1WNV A;  1UBB A;  1RCW A;  3B5O A;  1WNX A;  4G8P A;  2E7E A; 
#chains in the Genus database with same CATH homology
 1OZE A;  1S8C A;  2A2M A;  1WZG A;  1V8X A;  3HML A;  4LQX A;  4FN6 A;  1RTW A;  2QZC A;  2A2O A;  3B5P A;  4WD4 A;  3MOO A;  3K4F A;  3DDE A;  1WOV A;  2ZVU A;  2GM7 A;  4WWJ A;  1TO9 B;  4RAJ A;  1P3T A;  3HLX A;  1IW1 A;  1XJZ A;  2QCX A;  1N3U A;  2GM8 A;  1P3U A;  3NO6 A;  3RM5 A;  3CZY A;  1TO9 A;  1YAK A;  3HOK A;  4GPF A;  3IBX A;  1DVG A;  1N45 A;  4G99 A;  2Q4X A;  1WZD A;  1IX3 A;  4WX0 A;  3OQL A;  2Z68 A;  1XK2 A;  4GPH A;  2DY5 A;  1IW0 A;  1T5P A;  1IVJ A;  3I9T A;  1OYK A;  1TWR A;  1WZF A;  1OYL A;  1OTW A;  1SK7 A;  1OZR A;  1WOW A;  4G7U A;  2RGZ A;  4MEC A;  1S13 A;  4G7T A;  4G7L A;  1OZL A;  3BJD A;  4GPC A;  1TYH A;  1WE1 A;  1XK1 A;  4G8W A;  1XK0 A;  1IRM A;  1XK3 A;  1IX4 A;  5BTQ A;  3TGM A;  1UDD A;  4NY7 A;  1NI6 A;  4G98 A;  1VGI A;  1J2C A;  3HNH A;  4G7P A;  1OZW A;  2Q32 A;  1DVE A;  2RD3 A;  1Z72 A;  2QPP A;  2F2G A;  4GOH A;  1P3V A;  1TWN A;  3I8R A;  1WOX A;  1J77 A;  4WMH A;  1ULX A;  1OTV A;  1WNW A;  3I9U A;  2A6B A;  3MVU A;  4G8U A;  4WWZ A;  1YAF A;  1J02 A;  1WWM A;  1WNV A;  1UBB A;  1RCW A;  3B5O A;  1WNX A;  4G8P A;  2E7E A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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