1S20A

A novel nad binding protein revealed by the crystal structure of e. coli 2,3-diketogulonate reductase (yiak) northeast structural genomics consortium target er82
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
334
structure length
334
Chain Sequence
b'MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQALLE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Hypothetical oxidoreductase yiaK
molecule tags Oxidoreductase
source organism Escherichia coli
publication title A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK).
pubmed doi rcsb
total genus 98
structure length 334
sequence length 334
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.1.1.130: 3-dehydro-L-gulonate 2-dehydrogenase.
pdb deposition date 2004-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1s20A01
3.30.60.50 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Hypothetical oxidoreductase yiak; domain 3 1s20A03
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1s20A02
1X0AA 2X06A 1Z2IA 4H8AA 1WTJA 4FJUA 1NXUA 2CWHA 1VBIA 2CWFA 1V9NA 2G8YA 4FJSA 1S20A 3UOEA 3I0PA 1XRHA
chains in the Genus database with same CATH superfamily
4DNCA 3OXGA 3E2IA 1R0RI 2CJSC 4X62H 4OD6A 1Y1BA 4BA1I 3GOXA 4JI8H 1X4NA 4K0KH 2JYYA 1Y1CA 2JEBI 4PDBA 4HGUA 1MSZA 5E3RA 1DS3I 4X64H 4EC5A 2LTLA 1KHMA 4NZRM 5EX0A 3FC3A 5FUVA 1TUAA 1K7UA 2CWGA 3V69A 3SGBI 1LR9A 3BJIA 3R5CA 4E9JA 4LF9H 1KBEA 2CTKA 2N52A 1F0XA 2OU2A 2BL5A 4LF5H 2GKVA 3KDKA 2ARPF 3R5BA 1ODHA 1P9GA 2CWFA 3VDUA 3RU0A 4GKJH 1CE3A 1X0AA 2KMPA 4UXJA 2M5XA 4X66H 2E5RA 2WGCA 4OCHA 1J5KA 2NU2I 1V8CA 1OVOA 3EZJA 2GIVA 3QAHA 4GKKH 4DR6H 4B3SH 1ZZKA 4E1RA 2PT7G 2DB6A 1XNQH 4FJSA 4OX9H 4KHPH 1DS2I 4DR1H 4B3MH 1TBRR 1PPFI 2J87A 2PQUA 1MJBA 3TO9A 1HR0H 2JZXA 3OVOA 2JXDA 3SB1A 1U5KA 1FKAH 4B3TH 2ORVA 3QD7X 2CTJA 1XX6A 1TGSI 4JI1H 4IFDG 1WVNA 4DV2H 1HNWH 1W4RA 1FY7A 4LF8H 2HH3A 4LFAH 2ODDA 1IBKH 4NXNH 2K1HA 1CT0I 1FJGH 5J8CA 1TOTA 2F3CI 2NU3I 1CGII 3OXLA 3TJQA 2X52A 1H0ZA 1N34H 4SGBI 4AM3A 4LF4H 3VE5A 2KMRA 1J5EH 2N17A 2UXBH 2LRRA 5E3PA 2QQEA 2UVOA 1XMOH 2WCYA 3T1HH 2SGPI 2F4VH 3UEJA 3GKUA 4JI3H 4DR7H 2FPHX 4DUZH 4NBQA 5LMUH 1N13A 2N1AB 3TOAA 1ULMA 1WGTA 3D00A 2ROWA 2JE6I 3OETA 1I94H 2FMRA 4FJUA 2G8YA 2SGEI 3R5DA 2GKTI 4DV7H 1FYBA 4AQYH 2DKVA 1NUBA 1UHAA 5IT9W 1LR8A 2CWHA 2OPVA 2V1CC 1CHOI 2LUYA 2Y0MA 4JV5H 2VQEH 4NZTM 1ZZJA 2AXYA 2XRCA 1V9NA 2KCXA 5HQ8A 3UEYA 4NXMH 2LEOA 2E5LH 1OMTA 4OVOA 3KDGA 4UXHA 4DR2H 1FARA 4JCVE 1MJAA 2JVZA 1SGNI 2QQ0A 1HDLA 1K7VA 4JYAH 2GVIA 3J81W 1IBMH 2PQ8A 1W3SA 4DV1H 4JI4H 2E73A 1SGDI 1SEIA 2Y3MA 2OPUA 2OD1A 1DT4A 2ZQEA 2A20A 5HI7A 1CT2I 2PY9A 2OVOA 1HEVA 1TBQR 3VDPA 2W0TA 1TBNA 5DAEA 5J8FA 2DIPA 1ZZIA 4B8TA 3PDNA 1IBLH 1MT1A 1PCEA 2SGFI 5CCMA 2B8TA 3HH2C 4DV3H 1WE8A 3AEVB 1XBTA 2K9HA 2CTEA 4A24A 1AN7A 2RIJA 1HPTA 5JEAG 1Z2IA 5BR8H 1WTJA 1LR7A 4YHHH 4DR4H 4JI5H 3VKEA 2L8EA 1OMUA 4JVYA 3T1YH 4OO1G 2NN6G 2JZMA 1WHRA 4DR5H 1XA6A 2X3TA 1ULNA 4JVHA 1DTJA 2VRWB 1EC6A 2ANRA 1KBFA 5C0XG 3L7ZC 2ANNA 1WGCA 3UGDA 1X4MA 3UOEA 3I0PA 5LMNH 5JHWC 2UU9H 1MJ9A 2LF0A 1SGRI 1CT4I 2BA0A 3RF2A 2RC4A 2CPMA 4DV5H 2FFMA 1S20A 4AMLA 2HHHH 1TUSA 2FNFX 1S03G 1YU6C 1Z7KB 3TO7A 1VDDA 1K1GA 1ZTGA 2LTMA 1PJUA 4DR3H 5FLXW 1IW4A 3GR5A 2NU4I 4GI3C 1J4WA 1PQXA 3OXFA 1PTRA 3E59A 2V1CA 3JAMW 1HNZH 2ORWA 1VIGA 4WANA 2QPOA 1UVFA 2A1SA 1WKXA 3QTLD 2CTLA 2SGQI 5K36G 4JI6H 2HH2A 3NCVA 5DT9A 1XNRH 1N33H 1SGEI 4LFCH 3CXLA 1TIHA 5FUYA 4LF7H 1X4SA 3KY9A 2M6QA 2MJHA 2YUUA 2E3UA 7WGAA 4LF6H 2Z0SA 3UFFA 4E1PA 1X74A 5FUWA 3J7AK 5A2QW 2ZM6H 3QWPA 5E3QA 3TO6A 1N36H 1Q9BA 2ELIA 2LB7A 2JW6A 4JI7H 2DGRA 2L7XA 4B6DA 4FKDA 2CTFA 1P9ZA 2YQRA 1Y8FA 1YTPA 4WP4A 2JEAI 2P2RA 9WGAA 4JI0H 4YY3H 2SGDI 4DUYH 2CTMA 1M8BA 2QQDA 1BUSA 3OTOH 2BUSA 2J9RA 1R79A 3MEKA 4L9MA 4BA2I 4AIMA 3FSXA 3R5AA 1KMAA 3FAUA 1HNXH 5IWAH 2JA9A 2GKRI 2X06A 1VIHA 1OYVI 1TURA 1SGPI 1I6UA 1N32H 3U1KA 1CGJI 4QMFB 4B8CD 2VKCA 2YQPA 2B0UC 1AN1I 1CSOI 1TBOA 2CPQA 3TOBA 3FSYA 3SEKC 3UGIA 4G08A 2QNDA 1UVGA 2KMQA 2O4CA 4B3RH 2UUBH 3GABA 1PTQA 1IY5A 4MPIA 2UUAH 2UXCH 5CCLA 2ERWA 1IY6A 4LIJA 1XMQH 2ENZA 4X65H 2UZ3A 2UXDH 2ENNA 1K7TA 2P6AC 2D9IA 1FAQA 2M8WA 1V1HA 3J80W 5LL6b 2NU1I 1M8CA 1NXUA 2KMOA 1VBIA 2NU0I 1BMOA 1SGQI 1RFHA 2UUCH 3B4VC 4LFBH 1SGYI 1X9ZA 1UG8A 2WVJA 1ULKA 1HJAI 3UGLA 2OZUA 4UXIA 2N71A 2QQCA 5EX3A 2V53A 3SGQI 1XRHA 5FUXA 3OSSD 2VQFH 4WALA 4DV6H 1UUCA 4H8AA 1V1IA 4JI2H 4DV4H 3OL0A 2JA1A 4DV0H
chains in the Genus database with same CATH topology
1X0AA 2X06A 1Z2IA 4H8AA 1WTJA 4FJUA 1NXUA 2CWHA 1VBIA 2CWFA 1V9NA 2G8YA 4FJSA 1S20A 3UOEA 3I0PA 1XRHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X0A A;  2X06 A;  1Z2I A;  4H8A A;  1WTJ A;  4FJU A;  1NXU A;  2CWH A;  1VBI A;  2CWF A;  1V9N A;  2G8Y A;  4FJS A;  1S20 A;  3UOE A;  3I0P A;  1XRH A; 
#chains in the Genus database with same CATH topology
 4DNC A;  3OXG A;  3E2I A;  1R0R I;  2CJS C;  4X62 H;  4OD6 A;  1Y1B A;  4BA1 I;  3GOX A;  4JI8 H;  1X4N A;  4K0K H;  2JYY A;  1Y1C A;  2JEB I;  4PDB A;  4HGU A;  1MSZ A;  5E3R A;  1DS3 I;  4X64 H;  4EC5 A;  2LTL A;  1KHM A;  4NZR M;  5EX0 A;  3FC3 A;  5FUV A;  1TUA A;  1K7U A;  2CWG A;  3V69 A;  3SGB I;  1LR9 A;  3BJI A;  3R5C A;  4E9J A;  4LF9 H;  1KBE A;  2CTK A;  2N52 A;  1F0X A;  2OU2 A;  2BL5 A;  4LF5 H;  2GKV A;  3KDK A;  2ARP F;  3R5B A;  1ODH A;  1P9G A;  2CWF A;  3VDU A;  3RU0 A;  4GKJ H;  1CE3 A;  1X0A A;  2KMP A;  4UXJ A;  2M5X A;  4X66 H;  2E5R A;  2WGC A;  4OCH A;  1J5K A;  2NU2 I;  1V8C A;  1OVO A;  3EZJ A;  2GIV A;  3QAH A;  4GKK H;  4DR6 H;  4B3S H;  1ZZK A;  4E1R A;  2PT7 G;  2DB6 A;  1XNQ H;  4FJS A;  4OX9 H;  4KHP H;  1DS2 I;  4DR1 H;  4B3M H;  1TBR R;  1PPF I;  2J87 A;  2PQU A;  1MJB A;  3TO9 A;  1HR0 H;  2JZX A;  3OVO A;  2JXD A;  3SB1 A;  1U5K A;  1FKA H;  4B3T H;  2ORV A;  3QD7 X;  2CTJ A;  1XX6 A;  1TGS I;  4JI1 H;  4IFD G;  1WVN A;  4DV2 H;  1HNW H;  1W4R A;  1FY7 A;  4LF8 H;  2HH3 A;  4LFA H;  2ODD A;  1IBK H;  4NXN H;  2K1H A;  1CT0 I;  1FJG H;  5J8C A;  1TOT A;  2F3C I;  2NU3 I;  1CGI I;  3OXL A;  3TJQ A;  2X52 A;  1H0Z A;  1N34 H;  4SGB I;  4AM3 A;  4LF4 H;  3VE5 A;  2KMR A;  1J5E H;  2N17 A;  2UXB H;  2LRR A;  5E3P A;  2QQE A;  2UVO A;  1XMO H;  2WCY A;  3T1H H;  2SGP I;  2F4V H;  3UEJ A;  3GKU A;  4JI3 H;  4DR7 H;  2FPH X;  4DUZ H;  4NBQ A;  5LMU H;  1N13 A;  2N1A B;  3TOA A;  1ULM A;  1WGT A;  3D00 A;  2ROW A;  2JE6 I;  3OET A;  1I94 H;  2FMR A;  4FJU A;  2G8Y A;  2SGE I;  3R5D A;  2GKT I;  4DV7 H;  1FYB A;  4AQY H;  2DKV A;  1NUB A;  1UHA A;  5IT9 W;  1LR8 A;  2CWH A;  2OPV A;  2V1C C;  1CHO I;  2LUY A;  2Y0M A;  4JV5 H;  2VQE H;  4NZT M;  1ZZJ A;  2AXY A;  2XRC A;  1V9N A;  2KCX A;  5HQ8 A;  3UEY A;  4NXM H;  2LEO A;  2E5L H;  1OMT A;  4OVO A;  3KDG A;  4UXH A;  4DR2 H;  1FAR A;  4JCV E;  1MJA A;  2JVZ A;  1SGN I;  2QQ0 A;  1HDL A;  1K7V A;  4JYA H;  2GVI A;  3J81 W;  1IBM H;  2PQ8 A;  1W3S A;  4DV1 H;  4JI4 H;  2E73 A;  1SGD I;  1SEI A;  2Y3M A;  2OPU A;  2OD1 A;  1DT4 A;  2ZQE A;  2A20 A;  5HI7 A;  1CT2 I;  2PY9 A;  2OVO A;  1HEV A;  1TBQ R;  3VDP A;  2W0T A;  1TBN A;  5DAE A;  5J8F A;  2DIP A;  1ZZI A;  4B8T A;  3PDN A;  1IBL H;  1MT1 A;  1PCE A;  2SGF I;  5CCM A;  2B8T A;  3HH2 C;  4DV3 H;  1WE8 A;  3AEV B;  1XBT A;  2K9H A;  2CTE A;  4A24 A;  1AN7 A;  2RIJ A;  1HPT A;  5JEA G;  1Z2I A;  5BR8 H;  1WTJ A;  1LR7 A;  4YHH H;  4DR4 H;  4JI5 H;  3VKE A;  2L8E A;  1OMU A;  4JVY A;  3T1Y H;  4OO1 G;  2NN6 G;  2JZM A;  1WHR A;  4DR5 H;  1XA6 A;  2X3T A;  1ULN A;  4JVH A;  1DTJ A;  2VRW B;  1EC6 A;  2ANR A;  1KBF A;  5C0X G;  3L7Z C;  2ANN A;  1WGC A;  3UGD A;  1X4M A;  3UOE A;  3I0P A;  5LMN H;  5JHW C;  2UU9 H;  1MJ9 A;  2LF0 A;  1SGR I;  1CT4 I;  2BA0 A;  3RF2 A;  2RC4 A;  2CPM A;  4DV5 H;  2FFM A;  1S20 A;  4AML A;  2HHH H;  1TUS A;  2FNF X;  1S03 G;  1YU6 C;  1Z7K B;  3TO7 A;  1VDD A;  1K1G A;  1ZTG A;  2LTM A;  1PJU A;  4DR3 H;  5FLX W;  1IW4 A;  3GR5 A;  2NU4 I;  4GI3 C;  1J4W A;  1PQX A;  3OXF A;  1PTR A;  3E59 A;  2V1C A;  3JAM W;  1HNZ H;  2ORW A;  1VIG A;  4WAN A;  2QPO A;  1UVF A;  2A1S A;  1WKX A;  3QTL D;  2CTL A;  2SGQ I;  5K36 G;  4JI6 H;  2HH2 A;  3NCV A;  5DT9 A;  1XNR H;  1N33 H;  1SGE I;  4LFC H;  3CXL A;  1TIH A;  5FUY A;  4LF7 H;  1X4S A;  3KY9 A;  2M6Q A;  2MJH A;  2YUU A;  2E3U A;  7WGA A;  4LF6 H;  2Z0S A;  3UFF A;  4E1P A;  1X74 A;  5FUW A;  3J7A K;  5A2Q W;  2ZM6 H;  3QWP A;  5E3Q A;  3TO6 A;  1N36 H;  1Q9B A;  2ELI A;  2LB7 A;  2JW6 A;  4JI7 H;  2DGR A;  2L7X A;  4B6D A;  4FKD A;  2CTF A;  1P9Z A;  2YQR A;  1Y8F A;  1YTP A;  4WP4 A;  2JEA I;  2P2R A;  9WGA A;  4JI0 H;  4YY3 H;  2SGD I;  4DUY H;  2CTM A;  1M8B A;  2QQD A;  1BUS A;  3OTO H;  2BUS A;  2J9R A;  1R79 A;  3MEK A;  4L9M A;  4BA2 I;  4AIM A;  3FSX A;  3R5A A;  1KMA A;  3FAU A;  1HNX H;  5IWA H;  2JA9 A;  2GKR I;  2X06 A;  1VIH A;  1OYV I;  1TUR A;  1SGP I;  1I6U A;  1N32 H;  3U1K A;  1CGJ I;  4QMF B;  4B8C D;  2VKC A;  2YQP A;  2B0U C;  1AN1 I;  1CSO I;  1TBO A;  2CPQ A;  3TOB A;  3FSY A;  3SEK C;  3UGI A;  4G08 A;  2QND A;  1UVG A;  2KMQ A;  2O4C A;  4B3R H;  2UUB H;  3GAB A;  1PTQ A;  1IY5 A;  4MPI A;  2UUA H;  2UXC H;  5CCL A;  2ERW A;  1IY6 A;  4LIJ A;  1XMQ H;  2ENZ A;  4X65 H;  2UZ3 A;  2UXD H;  2ENN A;  1K7T A;  2P6A C;  2D9I A;  1FAQ A;  2M8W A;  1V1H A;  3J80 W;  5LL6 b;  2NU1 I;  1M8C A;  1NXU A;  2KMO A;  1VBI A;  2NU0 I;  1BMO A;  1SGQ I;  1RFH A;  2UUC H;  3B4V C;  4LFB H;  1SGY I;  1X9Z A;  1UG8 A;  2WVJ A;  1ULK A;  1HJA I;  3UGL A;  2OZU A;  4UXI A;  2N71 A;  2QQC A;  5EX3 A;  2V53 A;  3SGQ I;  1XRH A;  5FUX A;  3OSS D;  2VQF H;  4WAL A;  4DV6 H;  1UUC A;  4H8A A;  1V1I A;  4JI2 H;  4DV4 H;  3OL0 A;  2JA1 A;  4DV0 H; 
#chains in the Genus database with same CATH homology
 1X0A A;  2X06 A;  1Z2I A;  4H8A A;  1WTJ A;  4FJU A;  1NXU A;  2CWH A;  1VBI A;  2CWF A;  1V9N A;  2G8Y A;  4FJS A;  1S20 A;  3UOE A;  3I0P A;  1XRH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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