1S3LA

Structural and functional characterization of a novel archaeal phosphodiesterase
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
165
structure length
165
Chain Sequence
MKIGIMSDTHDHLPNIRKAIEIFNDENVETVIHCGDFVSLFVIKEFENLNANIIATYGNNDGERCKLKEWLKDINEENIIDDFISVEIDDLKFFITHGHHQSVLEMAIKSGLYDVVIYGHTHERVFEEVDDVLVINPGECCGYLTGIPTIGILDTEKKEYREIVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
pubmed doi rcsb
source organism Methanocaldococcus jannaschii
molecule tags Phosphodiesterase
molecule keywords Hypothetical protein MJ0936
total genus 51
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 1s3lA00
4JA9A 1M63A 2A22A 4FBQA 3PSNA 2HY1A 3RL3A 3ICFA 3H68A 4UT3A 1UTEA 2NPPC 2Z06A 1UF3A 4ORAA 5GTUA 2WDCA 4OR9A 1HPUA 2O8AA 2QFRA 1U32A 4F0ZA 4O5GA 4WWLA 1MF8A 4G9JA 4YKEA 3H60A 4ZVZA 2P6BA 4UT3B 3IB8A 3E7AA 4H1YP 1HP1A 2QJCA 1QFCA 4IYPC 3IVDA 4NZVA 3K7WC 4MOVA 3ZU0A 5HPEA 5JPFA 3QFKA 3DSDA 1S3NA 1S95A 3TGHA 4I5NC 2WDDA 2NYLC 4LU9A 4H2BA 2ZBMA 4V0VA 1S3MA 4B2OA 3V4YA 2XMOA 4H2IA 4DSYA 2NYMC 3IVEA 4DHLA 2Z72A 2WDEA 5JJTA 1Z2XA 4ZX2A 3KBPA 4LACC 2R17A 1G5BA 1AUIA 2BDXA 4LTYA 4I5LC 1S3LA 1OIDA 4H1SA 1OIEA 3ZTVA 3PSOA 4O43A 4ORBA 4Q7FA 2Z1AA 4KBPA 3QFNA 1OI8A 1IT6A 3P71C 2WDFA 3DW8C 2GJUA 3AV0A 4FBWA 2BCDA 2KKNA 3C5WC 3E7BA 4MP0A 1QHWA 2IE4C 2USHA 3QFOA 3AUZA 4FBKA 4MOYA 1WARA 3H66A 5JPEA 4M0VA 2YVTA 1TCOA 4HD0A 5DNYA 3THNA 1Z2WA 3H67A 5F3WA 2DFJA 1II7A 1SU1A 3JYFA 2IAEC 3C9FA 1T70A 2HYPA 3N5UA 1XZWA 2BQ8X 2QFPA 4FCXA 4KKZA 3QG5C 4UT2A 1USHA 5IOHA 3H69A 1S70A 3EGGA 4V0WA 4UWQA 1V73A 4O4KA 1NNWA 4J6OA 4TUIA 5J28A 3LL8A 3EGHA 3GVEA 3H62B 3FGAC 1FJMA 2CV9A 4DT2A 1S8EA 3DSCA 4H2GA 2JOGA 4H2FA 3T1IA 3THOB 5EQVA 2AHDA 3RQZA 4JA7A 2HYOA 5B8IA 3H64A 3K7VC 2NXFA 3IB7A 2Q8UA 3RL4A 4ORCA 2O8GA 3H61A 1W24A 4IL1A 4O24A 1T71A 3RL5A 2IE3C 4XPNA 3H63A 1KBPA 1WAO1 3HVQA 5C1VA 5INBA 1HO5A 3QFMA 1XM7A 4TUGA 4V0XA 3CK2A 1JK7A
chains in the Genus database with same CATH superfamily
4JA9A 1M63A 2A22A 4FBQA 3PSNA 2HY1A 3RL3A 3ICFA 3H68A 4UT3A 1UTEA 2NPPC 2Z06A 1UF3A 4ORAA 5GTUA 2WDCA 4OR9A 1HPUA 2O8AA 2QFRA 1U32A 4F0ZA 4O5GA 4WWLA 1MF8A 4G9JA 4YKEA 3H60A 4ZVZA 2P6BA 4UT3B 3IB8A 3E7AA 2ZO9B 4H1YP 1HP1A 2QJCA 1QFCA 4IYPC 3IVDA 4NZVA 3K7WC 4MOVA 3ZU0A 5HPEA 5JPFA 3QFKA 3DSDA 1S3NA 1S95A 3TGHA 4I5NC 2WDDA 2NYLC 4LU9A 4H2BA 2ZBMA 4V0VA 1S3MA 4B2OA 3V4YA 2XMOA 2ZOAA 4H2IA 4DSYA 2NYMC 3IVEA 3CK2A 2Z72A 2WDEA 4DHLA 5JJTA 1Z2XA 4ZX2A 3KBPA 4LACC 2R17A 1G5BA 1AUIA 2BDXA 4LTYA 2DXNA 4I5LC 1S3LA 1OIDA 4H1SA 1OIEA 3ZTVA 3PSOA 4O43A 4ORBA 4Q7FA 2Z1AA 4KBPA 3QFNA 1OI8A 1IT6A 3P71C 3DW8C 2GJUA 3AV0A 4FBWA 2BCDA 2KKNA 3C5WC 3E7BA 4MP0A 1QHWA 2IE4C 2USHA 3QFOA 3AUZA 4FBKA 4MOYA 1WARA 3H66A 5JPEA 4M0VA 2YVTA 1TCOA 4HD0A 5DNYA 3THNA 1Z2WA 3H67A 5F3WA 2DFJA 2DXLA 1II7A 1SU1A 3JYFA 2IAEC 3C9FA 1T70A 2HYPA 3N5UA 1XZWA 2BQ8X 2QFPA 4FCXA 4KKZA 3QG5C 4UT2A 1USHA 3D03A 5IOHA 3H69A 1S70A 3FLOA 3EGGA 4V0WA 4UWQA 1V73A 4O4KA 1NNWA 4J6OA 4TUIA 5J28A 3LL8A 3EGHA 3GVEA 3H62B 3FGAC 1FJMA 2CV9A 4DT2A 1S8EA 3DSCA 4H2GA 2JOGA 4H2FA 3T1IA 3THOB 5EQVA 2YEQA 2AHDA 4JA7A 3RQZA 2HYOA 5B8IA 3H64A 3K7VC 2NXFA 3IB7A 2Q8UA 3E0JA 4ORCA 3RL4A 2O8GA 3H61A 1W24A 4IL1A 4O24A 1T71A 3RL5A 2IE3C 4XPNA 3H63A 1KBPA 1WAO1 3HVQA 5C1VA 5INBA 1HO5A 3QFMA 1XM7A 4TUGA 4V0XA 2WDFA 1JK7A
chains in the Genus database with same CATH topology
4JA9A 1M63A 2A22A 4FBQA 3PSNA 2HY1A 3RL3A 3ICFA 3H68A 4UT3A 1UTEA 2NPPC 2Z06A 1UF3A 4ORAA 5GTUA 2WDCA 4OR9A 1HPUA 2O8AA 2QFRA 1U32A 4F0ZA 4O5GA 4WWLA 1MF8A 4G9JA 4YKEA 3H60A 4ZVZA 2P6BA 4UT3B 3IB8A 3E7AA 2ZO9B 4H1YP 1HP1A 2QJCA 1QFCA 4IYPC 3IVDA 4NZVA 3K7WC 4MOVA 3ZU0A 5HPEA 5JPFA 3QFKA 3DSDA 1S3NA 1S95A 3TGHA 4I5NC 2WDDA 2NYLC 4LU9A 4H2BA 2ZBMA 4V0VA 1S3MA 4B2OA 3V4YA 2XMOA 2ZOAA 4H2IA 4DSYA 2NYMC 3IVEA 3CK2A 2Z72A 2WDEA 4DHLA 5JJTA 1Z2XA 4ZX2A 3KBPA 4LACC 2R17A 1G5BA 1AUIA 2BDXA 4LTYA 2DXNA 4I5LC 1S3LA 1OIDA 4H1SA 1OIEA 3ZTVA 3PSOA 4O43A 4ORBA 4Q7FA 2Z1AA 4KBPA 3QFNA 1OI8A 1IT6A 3P71C 3DW8C 2GJUA 3AV0A 4FBWA 2BCDA 2KKNA 3C5WC 3E7BA 4MP0A 1QHWA 2IE4C 2USHA 3QFOA 3AUZA 4FBKA 4MOYA 1WARA 3H66A 5JPEA 4M0VA 2YVTA 1TCOA 4HD0A 5DNYA 3THNA 1Z2WA 3H67A 5F3WA 2DFJA 2DXLA 1II7A 1SU1A 3JYFA 2IAEC 3C9FA 1T70A 2HYPA 3N5UA 1XZWA 2BQ8X 2QFPA 4FCXA 4KKZA 3QG5C 4UT2A 1USHA 3D03A 5IOHA 3H69A 1S70A 3FLOA 3EGGA 4V0WA 4UWQA 1V73A 4O4KA 1NNWA 4J6OA 4TUIA 5J28A 3LL8A 3EGHA 3GVEA 3H62B 3FGAC 1FJMA 2CV9A 4DT2A 1S8EA 3DSCA 4H2GA 2JOGA 4H2FA 3T1IA 3THOB 5EQVA 2YEQA 2AHDA 4JA7A 3RQZA 2HYOA 5B8IA 3H64A 3K7VC 2NXFA 3IB7A 2Q8UA 3E0JA 4ORCA 3RL4A 2O8GA 3H61A 1W24A 4IL1A 4O24A 1T71A 3RL5A 2IE3C 4XPNA 3H63A 1KBPA 1WAO1 3HVQA 5C1VA 5INBA 1HO5A 3QFMA 1XM7A 4TUGA 4V0XA 2WDFA 1JK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JA9 A;  1M63 A;  2A22 A;  4FBQ A;  3PSN A;  2HY1 A;  3RL3 A;  3ICF A;  3H68 A;  4UT3 A;  1UTE A;  2NPP C;  2Z06 A;  1UF3 A;  4ORA A;  5GTU A;  2WDC A;  4OR9 A;  1HPU A;  2O8A A;  2QFR A;  1U32 A;  4F0Z A;  4O5G A;  4WWL A;  1MF8 A;  4G9J A;  4YKE A;  3H60 A;  4ZVZ A;  2P6B A;  4UT3 B;  3IB8 A;  3E7A A;  4H1Y P;  1HP1 A;  2QJC A;  1QFC A;  4IYP C;  3IVD A;  4NZV A;  3K7W C;  4MOV A;  3ZU0 A;  5HPE A;  5JPF A;  3QFK A;  3DSD A;  1S3N A;  1S95 A;  3TGH A;  4I5N C;  2WDD A;  2NYL C;  4LU9 A;  4H2B A;  2ZBM A;  4V0V A;  1S3M A;  4B2O A;  3V4Y A;  2XMO A;  4H2I A;  4DSY A;  2NYM C;  3IVE A;  4DHL A;  2Z72 A;  2WDE A;  5JJT A;  1Z2X A;  4ZX2 A;  3KBP A;  4LAC C;  2R17 A;  1G5B A;  1AUI A;  2BDX A;  4LTY A;  4I5L C;  1S3L A;  1OID A;  4H1S A;  1OIE A;  3ZTV A;  3PSO A;  4O43 A;  4ORB A;  4Q7F A;  2Z1A A;  4KBP A;  3QFN A;  1OI8 A;  1IT6 A;  3P71 C;  2WDF A;  3DW8 C;  2GJU A;  3AV0 A;  4FBW A;  2BCD A;  2KKN A;  3C5W C;  3E7B A;  4MP0 A;  1QHW A;  2IE4 C;  2USH A;  3QFO A;  3AUZ A;  4FBK A;  4MOY A;  1WAR A;  3H66 A;  5JPE A;  4M0V A;  2YVT A;  1TCO A;  4HD0 A;  5DNY A;  3THN A;  1Z2W A;  3H67 A;  5F3W A;  2DFJ A;  1II7 A;  1SU1 A;  3JYF A;  2IAE C;  3C9F A;  1T70 A;  2HYP A;  3N5U A;  1XZW A;  2BQ8 X;  2QFP A;  4FCX A;  4KKZ A;  3QG5 C;  4UT2 A;  1USH A;  5IOH A;  3H69 A;  1S70 A;  3EGG A;  4V0W A;  4UWQ A;  1V73 A;  4O4K A;  1NNW A;  4J6O A;  4TUI A;  5J28 A;  3LL8 A;  3EGH A;  3GVE A;  3H62 B;  3FGA C;  1FJM A;  2CV9 A;  4DT2 A;  1S8E A;  3DSC A;  4H2G A;  2JOG A;  4H2F A;  3T1I A;  3THO B;  5EQV A;  2AHD A;  3RQZ A;  4JA7 A;  2HYO A;  5B8I A;  3H64 A;  3K7V C;  2NXF A;  3IB7 A;  2Q8U A;  3RL4 A;  4ORC A;  2O8G A;  3H61 A;  1W24 A;  4IL1 A;  4O24 A;  1T71 A;  3RL5 A;  2IE3 C;  4XPN A;  3H63 A;  1KBP A;  1WAO 1;  3HVQ A;  5C1V A;  5INB A;  1HO5 A;  3QFM A;  1XM7 A;  4TUG A;  4V0X A;  3CK2 A;  1JK7 A; 
#chains in the Genus database with same CATH topology
 4JA9 A;  1M63 A;  2A22 A;  4FBQ A;  3PSN A;  2HY1 A;  3RL3 A;  3ICF A;  3H68 A;  4UT3 A;  1UTE A;  2NPP C;  2Z06 A;  1UF3 A;  4ORA A;  5GTU A;  2WDC A;  4OR9 A;  1HPU A;  2O8A A;  2QFR A;  1U32 A;  4F0Z A;  4O5G A;  4WWL A;  1MF8 A;  4G9J A;  4YKE A;  3H60 A;  4ZVZ A;  2P6B A;  4UT3 B;  3IB8 A;  3E7A A;  2ZO9 B;  4H1Y P;  1HP1 A;  2QJC A;  1QFC A;  4IYP C;  3IVD A;  4NZV A;  3K7W C;  4MOV A;  3ZU0 A;  5HPE A;  5JPF A;  3QFK A;  3DSD A;  1S3N A;  1S95 A;  3TGH A;  4I5N C;  2WDD A;  2NYL C;  4LU9 A;  4H2B A;  2ZBM A;  4V0V A;  1S3M A;  4B2O A;  3V4Y A;  2XMO A;  2ZOA A;  4H2I A;  4DSY A;  2NYM C;  3IVE A;  3CK2 A;  2Z72 A;  2WDE A;  4DHL A;  5JJT A;  1Z2X A;  4ZX2 A;  3KBP A;  4LAC C;  2R17 A;  1G5B A;  1AUI A;  2BDX A;  4LTY A;  2DXN A;  4I5L C;  1S3L A;  1OID A;  4H1S A;  1OIE A;  3ZTV A;  3PSO A;  4O43 A;  4ORB A;  4Q7F A;  2Z1A A;  4KBP A;  3QFN A;  1OI8 A;  1IT6 A;  3P71 C;  3DW8 C;  2GJU A;  3AV0 A;  4FBW A;  2BCD A;  2KKN A;  3C5W C;  3E7B A;  4MP0 A;  1QHW A;  2IE4 C;  2USH A;  3QFO A;  3AUZ A;  4FBK A;  4MOY A;  1WAR A;  3H66 A;  5JPE A;  4M0V A;  2YVT A;  1TCO A;  4HD0 A;  5DNY A;  3THN A;  1Z2W A;  3H67 A;  5F3W A;  2DFJ A;  2DXL A;  1II7 A;  1SU1 A;  3JYF A;  2IAE C;  3C9F A;  1T70 A;  2HYP A;  3N5U A;  1XZW A;  2BQ8 X;  2QFP A;  4FCX A;  4KKZ A;  3QG5 C;  4UT2 A;  1USH A;  3D03 A;  5IOH A;  3H69 A;  1S70 A;  3FLO A;  3EGG A;  4V0W A;  4UWQ A;  1V73 A;  4O4K A;  1NNW A;  4J6O A;  4TUI A;  5J28 A;  3LL8 A;  3EGH A;  3GVE A;  3H62 B;  3FGA C;  1FJM A;  2CV9 A;  4DT2 A;  1S8E A;  3DSC A;  4H2G A;  2JOG A;  4H2F A;  3T1I A;  3THO B;  5EQV A;  2YEQ A;  2AHD A;  4JA7 A;  3RQZ A;  2HYO A;  5B8I A;  3H64 A;  3K7V C;  2NXF A;  3IB7 A;  2Q8U A;  3E0J A;  4ORC A;  3RL4 A;  2O8G A;  3H61 A;  1W24 A;  4IL1 A;  4O24 A;  1T71 A;  3RL5 A;  2IE3 C;  4XPN A;  3H63 A;  1KBP A;  1WAO 1;  3HVQ A;  5C1V A;  5INB A;  1HO5 A;  3QFM A;  1XM7 A;  4TUG A;  4V0X A;  2WDF A;  1JK7 A; 
#chains in the Genus database with same CATH homology
 4JA9 A;  1M63 A;  2A22 A;  4FBQ A;  3PSN A;  2HY1 A;  3RL3 A;  3ICF A;  3H68 A;  4UT3 A;  1UTE A;  2NPP C;  2Z06 A;  1UF3 A;  4ORA A;  5GTU A;  2WDC A;  4OR9 A;  1HPU A;  2O8A A;  2QFR A;  1U32 A;  4F0Z A;  4O5G A;  4WWL A;  1MF8 A;  4G9J A;  4YKE A;  3H60 A;  4ZVZ A;  2P6B A;  4UT3 B;  3IB8 A;  3E7A A;  2ZO9 B;  4H1Y P;  1HP1 A;  2QJC A;  1QFC A;  4IYP C;  3IVD A;  4NZV A;  3K7W C;  4MOV A;  3ZU0 A;  5HPE A;  5JPF A;  3QFK A;  3DSD A;  1S3N A;  1S95 A;  3TGH A;  4I5N C;  2WDD A;  2NYL C;  4LU9 A;  4H2B A;  2ZBM A;  4V0V A;  1S3M A;  4B2O A;  3V4Y A;  2XMO A;  2ZOA A;  4H2I A;  4DSY A;  2NYM C;  3IVE A;  3CK2 A;  2Z72 A;  2WDE A;  4DHL A;  5JJT A;  1Z2X A;  4ZX2 A;  3KBP A;  4LAC C;  2R17 A;  1G5B A;  1AUI A;  2BDX A;  4LTY A;  2DXN A;  4I5L C;  1S3L A;  1OID A;  4H1S A;  1OIE A;  3ZTV A;  3PSO A;  4O43 A;  4ORB A;  4Q7F A;  2Z1A A;  4KBP A;  3QFN A;  1OI8 A;  1IT6 A;  3P71 C;  3DW8 C;  2GJU A;  3AV0 A;  4FBW A;  2BCD A;  2KKN A;  3C5W C;  3E7B A;  4MP0 A;  1QHW A;  2IE4 C;  2USH A;  3QFO A;  3AUZ A;  4FBK A;  4MOY A;  1WAR A;  3H66 A;  5JPE A;  4M0V A;  2YVT A;  1TCO A;  4HD0 A;  5DNY A;  3THN A;  1Z2W A;  3H67 A;  5F3W A;  2DFJ A;  2DXL A;  1II7 A;  1SU1 A;  3JYF A;  2IAE C;  3C9F A;  1T70 A;  2HYP A;  3N5U A;  1XZW A;  2BQ8 X;  2QFP A;  4FCX A;  4KKZ A;  3QG5 C;  4UT2 A;  1USH A;  3D03 A;  5IOH A;  3H69 A;  1S70 A;  3FLO A;  3EGG A;  4V0W A;  4UWQ A;  1V73 A;  4O4K A;  1NNW A;  4J6O A;  4TUI A;  5J28 A;  3LL8 A;  3EGH A;  3GVE A;  3H62 B;  3FGA C;  1FJM A;  2CV9 A;  4DT2 A;  1S8E A;  3DSC A;  4H2G A;  2JOG A;  4H2F A;  3T1I A;  3THO B;  5EQV A;  2YEQ A;  2AHD A;  4JA7 A;  3RQZ A;  2HYO A;  5B8I A;  3H64 A;  3K7V C;  2NXF A;  3IB7 A;  2Q8U A;  3E0J A;  4ORC A;  3RL4 A;  2O8G A;  3H61 A;  1W24 A;  4IL1 A;  4O24 A;  1T71 A;  3RL5 A;  2IE3 C;  4XPN A;  3H63 A;  1KBP A;  1WAO 1;  3HVQ A;  5C1V A;  5INB A;  1HO5 A;  3QFM A;  1XM7 A;  4TUG A;  4V0X A;  2WDF A;  1JK7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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