1S4DA

Crystal structure analysis of the s-adenosyl-l-methionine dependent uroporphyrinogen-iii c-methyltransferase sumt
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
265
structure length
256
Chain Sequence
FAGLPALEKGSVWLVGAGPGDPGLLTLHAANALRQADVIVHDALVNEDCLKLARPGAVLEFAGKRGPSPKQRDISLRLVELARAGNRVLRLKGGDPFVFGRGGEEALTLVEHQVPFRIVPGITAGIGGLAYAGIPVTHREVNHAVTFLTGHDRINWQGIASGSPVIVMYMAMKHIGAITANLIAGGRSPDEPVAFVCNAATPQQAVLETTLARAEADVAAAGLEPPAIVVVGEVVRLRAALDWIGALDGRKLAADP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure/Function Studies on a S-Adenosyl-l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis
pubmed doi rcsb
source organism Pseudomonas denitrificans
molecule tags Transferase
molecule keywords Uroporphyrin-III C-methyltransferase
total genus 68
structure length 256
sequence length 265
chains with identical sequence B, D, E, F, G, H, I, J, K, L, M
ec nomenclature ec 2.1.1.107: Uroporphyrinogen-III C-methyltransferase.
pdb deposition date 2004-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00590 TP_methylase Tetrapyrrole (Corrin/Porphyrin) Methylases
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.950.10 Alpha Beta 2-Layer Sandwich Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 1s4dA02
3.40.1010.10 Alpha Beta 3-Layer(aba) Sandwich Cobalt-precorrin-4 Transmethylase; domain 1 Cobalt-precorrin-4 Transmethylase; Domain 1 1s4dA01
2E07A 2DV3A 2YBOA 2E8QA 2E17A 2PB5A 2E0NA 2EGBA 2EL1A 2P6KA 2HUXA 2DSIA 2DSHA 2E15A 5HW4A 2EEQA 2PCIA 2NPNA 2E8HA 2DXXA 2EMUA 2P6IA 2EL0A 4E16A 2ELDA 2P2XA 1WDEA 3I4TA 1CBFA 2Z6RA 2EGSA 2DV7A 1PJTA 3KWPA 2P6LA 1VCEA 1VHVA 2BB3A 3FFYA 2ELEA 1WNGA 2PCMA 2PB6A 2PCGA 2P9DA 3ND1A 2EH2A 2EL3A 1S4DA 2DSGA 1WYZA 2E4RA 2EJJA 2E16A 2HUVA 2PB4A 2EK4A 2OWUA 2EH5A 2E08A 2HUQA 1VE2A 2YBQA 2P5CA 2OWFA 3NUTA 2E0KA 2E8SA 1VA0A 2ED5A 2DXWA 2EL2A 2HUTA 2HR8A 2EHLA 2ZVBA 2ENIA 2E4NA 2EK2A 1PJSA 2ED3A 2OWKA 2DXVA 2E7RA 2CBFA 3NEIA 2ZVCA 2EGLA 2EK3A 3HH1A 2DEKA 2PCHA 3FQ6A 2OWGA 2EH4A 2DV5A 1PJQA 2QBUA 2P6DA 2EJKA 2EKAA 2EN5A 2P5FA 1V9AA 2OWVA 2EJZA 2EHCA 2EMRA 2PCKA 3NDCA 2E8RA 2EK7A 2PCAA 2DV4A
chains in the Genus database with same CATH superfamily
2E07A 4MUXA 2DV3A 2YBOA 2E8QA 2E17A 2PB5A 2KYYA 3F7TA 2E0NA 2EGBA 2EL1A 4MUYA 3T0FA 2P6KA 2HUXA 2DSIA 2DSHA 3UWMA 2E15A 5HW4A 2EEQA 2PCIA 2NPNA 2E8HA 2DXXA 3T0GA 2EMUA 2P6IA 2EL0A 4E16A 2ELDA 2P2XA 1WDEA 3I4TA 1CBFA 2Z6RA 3TIXB 2EGSA 2DV7A 1PJTA 3ZGNA 3KWPA 2P6LA 1VCEA 3URKA 1VHVA 2BB3A 3FFYA 2ELEA 1WNGA 2PCMA 2PB6A 2PCGA 2P9DA 3DNFA 3SZUA 3LMMA 3ND1A 2EH2A 2EL3A 1S4DA 2DSGA 1WYZA 2E4RA 2EJJA 2E16A 3ZGLA 3UV7A 2HUVA 2PB4A 2EK4A 4H4DA 2OWUA 2EH5A 2E08A 3KE8A 3KE9A 4EB3A 2HUQA 1VE2A 2YBQA 4MV5A 2P5CA 2OWFA 3NUTA 2E0KA 3UV6A 2E8SA 4H4CA 3UV3A 1VA0A 3UTCA 2ED5A 3UTDA 2DXWA 2EL2A 3KEFA 4H4EA 2HUTA 2HR8A 2EHLA 2ZVBA 2ENIA 2E4NA 2EK2A 3SZOA 1PJSA 2ED3A 2OWKA 2DXVA 2E7RA 2CBFA 4MV0A 3NEIA 2ZVCA 2EGLA 2EK3A 3HH1A 2DEKA 2PCHA 3KELA 3FQ6A 4N7BA 2OWGA 3SZLA 2EH4A 2DV5A 1PJQA 2QBUA 2P6DA 2EJKA 2EKAA 2EN5A 2P5FA 1V9AA 2OWVA 2EJZA 2EHCA 2EMRA 3KEMA 2PCKA 3NDCA 2E8RA 2EK7A 2PCAA 2DV4A
chains in the Genus database with same CATH topology
2E07A 4MUXA 2DV3A 2YBOA 2E8QA 2E17A 2PB5A 2KYYA 3F7TA 2E0NA 2EGBA 2EL1A 4MUYA 3T0FA 2P6KA 2HUXA 2DSIA 2DSHA 3UWMA 2E15A 5HW4A 2EEQA 2PCIA 2NPNA 2E8HA 2DXXA 3T0GA 2EMUA 2P6IA 2EL0A 4E16A 2ELDA 2P2XA 1WDEA 3I4TA 1CBFA 2Z6RA 3TIXB 2EGSA 2DV7A 1PJTA 3ZGNA 3KWPA 2P6LA 1VCEA 3URKA 1VHVA 2BB3A 3FFYA 2ELEA 1WNGA 2PCMA 2PB6A 2PCGA 2P9DA 3DNFA 3SZUA 3LMMA 3ND1A 2EH2A 2EL3A 1S4DA 2DSGA 1WYZA 2E4RA 2EJJA 2E16A 3ZGLA 3UV7A 2HUVA 2PB4A 2EK4A 4H4DA 2OWUA 2EH5A 2E08A 3KE8A 3KE9A 4EB3A 2HUQA 1VE2A 2YBQA 4MV5A 2P5CA 2OWFA 3NUTA 2E0KA 3UV6A 2E8SA 4H4CA 3UV3A 1VA0A 3UTCA 2ED5A 3UTDA 2DXWA 2EL2A 3KEFA 4H4EA 2HUTA 2HR8A 2EHLA 2ZVBA 2ENIA 2E4NA 2EK2A 3SZOA 1PJSA 2ED3A 2OWKA 2DXVA 2E7RA 2CBFA 4MV0A 3NEIA 2ZVCA 2EGLA 2EK3A 3HH1A 2DEKA 2PCHA 3KELA 3FQ6A 4N7BA 2OWGA 3SZLA 2EH4A 2DV5A 1PJQA 2QBUA 2P6DA 2EJKA 2EKAA 2EN5A 2P5FA 1V9AA 2OWVA 2EJZA 2EHCA 2EMRA 3KEMA 2PCKA 3NDCA 2E8RA 2EK7A 2PCAA 2DV4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E07 A;  2DV3 A;  2YBO A;  2E8Q A;  2E17 A;  2PB5 A;  2E0N A;  2EGB A;  2EL1 A;  2P6K A;  2HUX A;  2DSI A;  2DSH A;  2E15 A;  5HW4 A;  2EEQ A;  2PCI A;  2NPN A;  2E8H A;  2DXX A;  2EMU A;  2P6I A;  2EL0 A;  4E16 A;  2ELD A;  2P2X A;  1WDE A;  3I4T A;  1CBF A;  2Z6R A;  2EGS A;  2DV7 A;  1PJT A;  3KWP A;  2P6L A;  1VCE A;  1VHV A;  2BB3 A;  3FFY A;  2ELE A;  1WNG A;  2PCM A;  2PB6 A;  2PCG A;  2P9D A;  3ND1 A;  2EH2 A;  2EL3 A;  1S4D A;  2DSG A;  1WYZ A;  2E4R A;  2EJJ A;  2E16 A;  2HUV A;  2PB4 A;  2EK4 A;  2OWU A;  2EH5 A;  2E08 A;  2HUQ A;  1VE2 A;  2YBQ A;  2P5C A;  2OWF A;  3NUT A;  2E0K A;  2E8S A;  1VA0 A;  2ED5 A;  2DXW A;  2EL2 A;  2HUT A;  2HR8 A;  2EHL A;  2ZVB A;  2ENI A;  2E4N A;  2EK2 A;  1PJS A;  2ED3 A;  2OWK A;  2DXV A;  2E7R A;  2CBF A;  3NEI A;  2ZVC A;  2EGL A;  2EK3 A;  3HH1 A;  2DEK A;  2PCH A;  3FQ6 A;  2OWG A;  2EH4 A;  2DV5 A;  1PJQ A;  2QBU A;  2P6D A;  2EJK A;  2EKA A;  2EN5 A;  2P5F A;  1V9A A;  2OWV A;  2EJZ A;  2EHC A;  2EMR A;  2PCK A;  3NDC A;  2E8R A;  2EK7 A;  2PCA A;  2DV4 A; 
#chains in the Genus database with same CATH topology
 2E07 A;  4MUX A;  2DV3 A;  2YBO A;  2E8Q A;  2E17 A;  2PB5 A;  2KYY A;  3F7T A;  2E0N A;  2EGB A;  2EL1 A;  4MUY A;  3T0F A;  2P6K A;  2HUX A;  2DSI A;  2DSH A;  3UWM A;  2E15 A;  5HW4 A;  2EEQ A;  2PCI A;  2NPN A;  2E8H A;  2DXX A;  3T0G A;  2EMU A;  2P6I A;  2EL0 A;  4E16 A;  2ELD A;  2P2X A;  1WDE A;  3I4T A;  1CBF A;  2Z6R A;  3TIX B;  2EGS A;  2DV7 A;  1PJT A;  3ZGN A;  3KWP A;  2P6L A;  1VCE A;  3URK A;  1VHV A;  2BB3 A;  3FFY A;  2ELE A;  1WNG A;  2PCM A;  2PB6 A;  2PCG A;  2P9D A;  3DNF A;  3SZU A;  3LMM A;  3ND1 A;  2EH2 A;  2EL3 A;  1S4D A;  2DSG A;  1WYZ A;  2E4R A;  2EJJ A;  2E16 A;  3ZGL A;  3UV7 A;  2HUV A;  2PB4 A;  2EK4 A;  4H4D A;  2OWU A;  2EH5 A;  2E08 A;  3KE8 A;  3KE9 A;  4EB3 A;  2HUQ A;  1VE2 A;  2YBQ A;  4MV5 A;  2P5C A;  2OWF A;  3NUT A;  2E0K A;  3UV6 A;  2E8S A;  4H4C A;  3UV3 A;  1VA0 A;  3UTC A;  2ED5 A;  3UTD A;  2DXW A;  2EL2 A;  3KEF A;  4H4E A;  2HUT A;  2HR8 A;  2EHL A;  2ZVB A;  2ENI A;  2E4N A;  2EK2 A;  3SZO A;  1PJS A;  2ED3 A;  2OWK A;  2DXV A;  2E7R A;  2CBF A;  4MV0 A;  3NEI A;  2ZVC A;  2EGL A;  2EK3 A;  3HH1 A;  2DEK A;  2PCH A;  3KEL A;  3FQ6 A;  4N7B A;  2OWG A;  3SZL A;  2EH4 A;  2DV5 A;  1PJQ A;  2QBU A;  2P6D A;  2EJK A;  2EKA A;  2EN5 A;  2P5F A;  1V9A A;  2OWV A;  2EJZ A;  2EHC A;  2EMR A;  3KEM A;  2PCK A;  3NDC A;  2E8R A;  2EK7 A;  2PCA A;  2DV4 A; 
#chains in the Genus database with same CATH homology
 2E07 A;  4MUX A;  2DV3 A;  2YBO A;  2E8Q A;  2E17 A;  2PB5 A;  2KYY A;  3F7T A;  2E0N A;  2EGB A;  2EL1 A;  4MUY A;  3T0F A;  2P6K A;  2HUX A;  2DSI A;  2DSH A;  3UWM A;  2E15 A;  5HW4 A;  2EEQ A;  2PCI A;  2NPN A;  2E8H A;  2DXX A;  3T0G A;  2EMU A;  2P6I A;  2EL0 A;  4E16 A;  2ELD A;  2P2X A;  1WDE A;  3I4T A;  1CBF A;  2Z6R A;  3TIX B;  2EGS A;  2DV7 A;  1PJT A;  3ZGN A;  3KWP A;  2P6L A;  1VCE A;  3URK A;  1VHV A;  2BB3 A;  3FFY A;  2ELE A;  1WNG A;  2PCM A;  2PB6 A;  2PCG A;  2P9D A;  3DNF A;  3SZU A;  3LMM A;  3ND1 A;  2EH2 A;  2EL3 A;  1S4D A;  2DSG A;  1WYZ A;  2E4R A;  2EJJ A;  2E16 A;  3ZGL A;  3UV7 A;  2HUV A;  2PB4 A;  2EK4 A;  4H4D A;  2OWU A;  2EH5 A;  2E08 A;  3KE8 A;  3KE9 A;  4EB3 A;  2HUQ A;  1VE2 A;  2YBQ A;  4MV5 A;  2P5C A;  2OWF A;  3NUT A;  2E0K A;  3UV6 A;  2E8S A;  4H4C A;  3UV3 A;  1VA0 A;  3UTC A;  2ED5 A;  3UTD A;  2DXW A;  2EL2 A;  3KEF A;  4H4E A;  2HUT A;  2HR8 A;  2EHL A;  2ZVB A;  2ENI A;  2E4N A;  2EK2 A;  3SZO A;  1PJS A;  2ED3 A;  2OWK A;  2DXV A;  2E7R A;  2CBF A;  4MV0 A;  3NEI A;  2ZVC A;  2EGL A;  2EK3 A;  3HH1 A;  2DEK A;  2PCH A;  3KEL A;  3FQ6 A;  4N7B A;  2OWG A;  3SZL A;  2EH4 A;  2DV5 A;  1PJQ A;  2QBU A;  2P6D A;  2EJK A;  2EKA A;  2EN5 A;  2P5F A;  1V9A A;  2OWV A;  2EJZ A;  2EHC A;  2EMR A;  3KEM A;  2PCK A;  3NDC A;  2E8R A;  2EK7 A;  2PCA A;  2DV4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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