1SA4B

Human protein farnesyltransferase complexed with fpp and r115777
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
410
structure length
410
Chain Sequence
SSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein farnesyltransferase/geranylgeranyltransferase type I
publication title Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 151
structure length 410
sequence length 410
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2004-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1sa4B00
2ZIRB 5FO9B 4KKIA 1H3AA 1FT2B 4M76A 5FO7B 2ZISB 3RJ3A 1JCQB 2F0YB 3C72B 4YDOB 1O1RB 4GTQB 2G0DA 3KQ4A 1H3CA 1LD7B 1LD8B 3CU7A 3E33B 2PMVA 4GTRB 4D94A 1TN8B 4D4DA 4MU9A 4GTTB 3HXBB 1H35A 1O79A 3EU5B 1N4QB 1O6HA 3DSUB 3DSXB 5JPMB 1N4SB 2H6IB 1JCRB 2V8IA 3K7XA 3Q79B 4FXGB 1UMPA 1KZOB 1W6JA 2XQWA 4BOJA 2BEDB 2V3PA 3OEDA 1TNUB 2H6HB 4LNBB 1S64B 1D8DB 1GHQA 3PZ1B 2R2LB 4ZH1A 2NOJA 4GTVB 2V3NA 1N9AB 1LTXB 2XWBB 3PZ2B 3KSLB 1DCEB 1FPPB 2GOXA 5FOBB 1QQFA 1X81B 3E37B 3E34B 2WIIB 2I07B 3DSSB 3KLSA 1SQCA 4BOKA 1O5MB 1TNZB 2XWJB 1HZFA 4V1RA 1GXNA 1FT1B 1GSZA 3HXDB 3HXFB 1GXOA 1TN6B 3DPYB 1H3BA 2H6GB 4D4CA 3DSTB 3SFYB 2A73B 2WY8A 3SQCA 3Q73B 4YDEB 1TN7B 1O1TB 3KSQB 4EHMB 3SFXB 4LNGB 2V8JA 1O6QA 2H6FB 1S63B 4GTMB 3HXCB 3D5RA 3DSVB 3G6JB 1H36A 1N4PB 4L9PB 4ONTA 1SA4B 2PN5A 4FXKB 1KZPB 1W6KA 2SQCA 4ZRPA 2WINB 1TNOB 1NI1B 3EUVB 4KKJA 3DRAB 5AGDA 2BB6A 2BBCA 4D4AA 3OXUA 1O1SB 1TNYB 1N95B 4GTOB 5JPNB 3PZ3B 1C3DA 1O6RA 4GTSB 3Q75B 4LNVA 2WY7A 1H37A 1N4RB 2B39A 2IEJB 3PZ4B 1GXMA 4MBGB 3E32B 4V1SA 3E30B 1JCSB 1NL4B 3Q7AB 2V8KA 1MZCB 3HXEB 5FO8B 4D4BA 1TNBB 1H39A 2BB5A 1D8EB 1R76A 4ZRQA 1SA5B 3DSWB 1QSJA 3Q7FB 3D5SA 1QBQB 3Q78B 4C1SA 4GTPB 2G02A 1N94B
chains in the Genus database with same CATH superfamily
2ZIRB 5FO9B 2FUZA 1V7VA 1KWFA 3RJ3A 4OJZA 1GAIA 1WZZA 1LXMA 1W3YA 3WIWA 3X17A 3RRSA 3K11A 2PMVA 1G87A 3TF4A 1HX9A 4GTTB 2FBAA 1H35A 4CE7A 1HM2A 1HM3A 1KREA 1O6HA 3AFJA 3DSUB 2DROA 4FNVA 2V8IA 3K7XA 3P5RA 3Q79B 1GAHA 2B4FA 1W6JA 2XQWA 1FBWA 1N7RA 5EATA 1X1JA 5ILHA 1CEMA 1TNUB 4LNBB 1D8DB 1GHQA 1L2AA 5GZKA 4FJQA 5M7IA 2QNOA 3A3VA 4JJJA 1KKTA 1FPPB 2GOXA 1QQFA 5IKHA 3SAEA 2WIIB 5JMDA 3E6UA 3DSSB 3VSMA 4J5TA 4BOKA 2ONGA 3HXFB 1AYXA 3M74A 1TN6B 3WIQA 1EGUA 1DOGA 4D4CA 1IA6A 3CIHA 1F9GA 3KSQB 4LNGB 2V8JA 1S63B 3D5RA 3DSVB 3G6JB 4ONTA 2PN5A 1FCEA 1NI1B 4KKJA 2AHGA 2P0VA 2BBCA 4ZH5A 3M73A 3OXUA 1JS4A 1TNYB 1N7OA 1N95B 3T33A 3ACSA 3WIRA 1CB8A 2CQTA 4GTSB 3Q75B 1N22A 3G4FA 1HXAA 3QXFA 4OK4A 2B39A 2IEJB 3M02A 1GXMA 1HCUA 4MBGB 1RWGA 3E32B 4GAXA 3SDUA 4DI5A 3E30B 5FO8B 3Q7AB 1MZCB 3E7JA 4D4BA 3M72A 1TNBB 5IL8A 1UT9A 1GA2A 3W5NA 1SA5B 3ANJA 1HXGA 2EACA 1AGMA 1CLCA 4LIXA 3QFZA 1OJOA 4Z4JA 1H3AA 1FT2B 5FO7B 1N7PA 2XFGA 1JCQB 4YDOB 1O1RB 3KQ4A 1H14A 1H3CA 3W7XA 2RGKA 3EQAA 4Z4LA 4D4DA 3QDEA 5CA3A 5DGQA 5IKAA 4MU9A 2ZZRA 1ULVA 3EU5B 2FUQA 3W7TA 1N4QB 1J0MA 1HV6A 3DSXB 4AYQA 2X03A 3WKHA 2E24A 4NEIA 5DGRA 4Q88A 5CD2A 2BRPA 2BEDB 2DRQA 2V3PA 1VD5A 1RWAA 4WVCA 2AHFA 1N9AB 1RW9A 2XWBB 3PZ2B 3KSLB 2E22A 5IM1A 1DCEB 1X9DA 1KSCA 3EU8A 1HMUA 3RSYA 5JMFA 5ILDA 3E34B 1IS9A 4TXTA 2WCOA 3VW5A 1O5MB 1N23A 3QFYA 1OJPA 1GSZA 4F13A 1N1ZA 5ILKA 1H3BA 3DSTB 4KTRA 3SQCA 3QSPA 1TN7B 4EHMB 1O6QA 3E73A 1XW2A 1H36A 3PYAA 3WKGA 4FXKB 1KZPB 1W6KA 1X1IA 4ZRPA 5AGDA 3WC3A 4WU0A 4D4AA 3SDQA 1O1SB 3P5PA 1J0NA 3D3IA 5JPNB 1WU4A 1FO3A 1O6RA 1V7XA 5GW7A 2WY7A 4WVAA 2FUTA 2EADA 1N24A 2WYNA 4L0GA 2EABA 1N7QA 2DRSA 5E2JA 2BB5A 1F9DA 4ZRQA 4OZWA 2NVPA 5ILZA 3DSWB 1QSJA 4WVBA 3Q7FB 3D5SA 1QBQB 3Q78B 4KTPA 4AYOA 1F9OA 3WUXA 1N94B 3QXQA 3ANKA 4KKIA 4M76A 1N1BA 5IK9A 4E1YA 1LF6A 1UG9A 3ANIA 2G0DA 4GTQB 1L1YA 4FUSA 1LD8B 3CU7A 2A8ZA 4D94A 1TN8B 2EAEA 2RI9A 3SDVA 3HXBB 3WKIA 3W7WA 3N0FA 5IL3A 3NNBA 4Q2BA 5EAUA 1V7WA 5JPMB 1KS8A 1N4SB 2H6IB 3P2CA 1UMPA 2FV0A 5M7YA 1FO2A 4BOJA 1FAEA 3OEDA 1C82A 2H6HB 3PMMA 1S64B 4ZH1A 1X1HA 4GTVB 2V3NA 3W7SA 4YCRA 5FOBB 4OZVA 3ON6A 5EASA 3PYBA 3WKFA 5DHIA 3S4CA 2I07B 1TNZB 1HN0A 4V1RA 2Q1FA 4MMIA 1FT1B 2DRRA 4AYPA 1N21A 4AYRA 2RI8A 3DPYB 3S4AA 4EL8A 2WY8A 3H7LA 1KFGA 1O1TB 1RWHA 2BRWA 5GY3A 3W7UA 1QAZA 2H6FB 3HXCB 3LZ9A 1SA4B 1LOHA 2D5JA 1WU5A 2WINB 3DRAB 2BB6A 5ILJA 1RWFA 3W5MA 1H13A 1TF4A 4ZG8A 3NFVA 3M78A 3H2WA 3QG0A 4GTOB 1KRFA 4CJ1A 3PZ3B 1C3DA 3E80A 4LNVA 1V5DA 1OJNA 4CJ0A 2AFAA 1N4RB 3M76A 3PZ4B 2OKXA 1JCSB 1I8QA 2V8KA 1XWQA 3A0OA 2ONHA 3M7LA 2GH4A 3QPFA 4C1SA 4GTPB 1NXCA 1XWTA 2G02A 5IK6A 1KSDA 3VSNA 4OK2A 1WU6A 3M77A 2JF4A 3M7EA 2ZISB 3QT3A 2F0YB 3C72B 4L6XA 1G9JA 1LD7B 2GZ6A 2CQSA 1FBOA 3E33B 1RWCA 4GTRB 3M75A 1HXCA 1N7NA 5CZLA 1OJMA 5MEHA 1O79A 3M00A 3RX8A 3QWTA 1H12A 1N20A 4DOEA 1JCRB 4FXGB 1KZOB 3VXDA 1IA7A 1V5CA 3S9VA 3PZ1B 2R2LB 1FP3A 3S4BA 2NOJA 2JJBA 2BRVX 3RENA 4DODA 1LTXB 3GT5A 3SDRA 3M7CA 2VN4A 5IK0A 1X81B 1FMIA 5C05A 3E37B 3AFLA 3GZKA 3RX7A 5DHKA 3QT9A 3KLSA 1RQ5A 1SQCA 3M01A 2YIKA 2XWJB 1K72A 1HZFA 4GL3A 1GXNA 2Z07A 3EZ8A 4MMHA 1F1SA 3HXDB 1GXOA 3QRYA 2H6GB 3ACTA 5ILIA 3SFYB 2A73B 2JG0A 3Q73B 4YDEB 3SDTA 3SFXB 4RNQA 4GTMB 3H3KA 3M7BA 1DL2A 4L9PB 5KKBA 1N4PB 3RX5A 4XUVA 1G9GA 1NC5A 2SQCA 1TNOB 1HMWA 3EUVB 5ILYA 4TF4A 1LXKA 3N0GA 2F6DA 2FV1A 4F10A 2D8LA 1LF9A 1H37A 1GLMA 2ZBLA 2VN7A 4V1SA 1NL4B 3HXEB 3GLYA 3S4DA 1H39A 2J5CA 3M71A 1D8EB 1R76A 2WDAA 3G4DA 1G6IA 1H54A 4QT9A
chains in the Genus database with same CATH topology
2ZIRB 5FO9B 2FUZA 1V7VA 1KWFA 3RJ3A 1GAIA 1WZZA 3WIWA 3X17A 3RRSA 3K11A 2PMVA 1G87A 3TF4A 4GTTB 2FBAA 1H35A 4CE7A 1KREA 1O6HA 3AFJA 3DSUB 2DROA 2V8IA 3K7XA 3P5RA 3Q79B 1GAHA 2B4FA 1W6JA 2XQWA 1FBWA 1CEMA 1TNUB 4LNBB 1D8DB 1GHQA 1L2AA 5GZKA 5M7IA 2QNOA 3A3VA 4JJJA 1KKTA 1FPPB 2GOXA 1QQFA 3SAEA 2WIIB 3E6UA 3DSSB 4BOKA 4J5TA 3HXFB 1AYXA 3M74A 1TN6B 3WIQA 1DOGA 4D4CA 1IA6A 3CIHA 3KSQB 4LNGB 2V8JA 1S63B 3D5RA 3DSVB 3G6JB 4ONTA 2PN5A 1FCEA 1NI1B 4KKJA 2AHGA 2P0VA 2BBCA 4ZH5A 3M73A 3OXUA 1JS4A 1TNYB 1N95B 3T33A 3ACSA 3WIRA 2CQTA 4GTSB 3Q75B 3QXFA 2B39A 2IEJB 1GXMA 1HCUA 4MBGB 3E32B 3SDUA 3E30B 5FO8B 3Q7AB 1MZCB 4D4BA 3M72A 1TNBB 1UT9A 1GA2A 3W5NA 1SA5B 3ANJA 2EACA 1AGMA 1CLCA 4LIXA 3QFZA 4Z4JA 1H3AA 1FT2B 5FO7B 2XFGA 1JCQB 4YDOB 1O1RB 3KQ4A 1H14A 1H3CA 3W7XA 2RGKA 3EQAA 4Z4LA 4D4DA 3QDEA 5CA3A 5DGQA 4MU9A 2ZZRA 1ULVA 3EU5B 3W7TA 1N4QB 3DSXB 4AYQA 3WKHA 5DGRA 4Q88A 5CD2A 2BEDB 2DRQA 2V3PA 1VD5A 4WVCA 2AHFA 1N9AB 2XWBB 3PZ2B 3KSLB 1DCEB 1X9DA 1KSCA 3EU8A 3RSYA 3E34B 1IS9A 4TXTA 3VW5A 1O5MB 3QFYA 1GSZA 1H3BA 3DSTB 4KTRA 3SQCA 3QSPA 1TN7B 4EHMB 1O6QA 3E73A 1XW2A 1H36A 3PYAA 3WKGA 4FXKB 1KZPB 1W6KA 4ZRPA 5AGDA 3WC3A 4WU0A 4D4AA 3SDQA 1O1SB 3P5PA 3D3IA 5JPNB 1WU4A 1FO3A 1O6RA 1V7XA 5GW7A 2WY7A 4WVAA 2EADA 2WYNA 4L0GA 2EABA 2DRSA 5E2JA 2BB5A 1F9DA 4ZRQA 2NVPA 3DSWB 1QSJA 4WVBA 3Q7FB 3D5SA 1QBQB 3Q78B 4KTPA 4AYOA 1F9OA 3WUXA 1N94B 3QXQA 3ANKA 4KKIA 4M76A 1LF6A 1UG9A 3ANIA 2G0DA 4GTQB 1L1YA 4FUSA 1LD8B 3CU7A 2A8ZA 4D94A 1TN8B 2EAEA 2RI9A 3SDVA 3HXBB 3WKIA 3W7WA 4Q2BA 1V7WA 5JPMB 1KS8A 1N4SB 2H6IB 3P2CA 1UMPA 2FV0A 5M7YA 1FO2A 4BOJA 3OEDA 1FAEA 3PMMA 2H6HB 1S64B 4ZH1A 4GTVB 2V3NA 3W7SA 4YCRA 5FOBB 3WKFA 3ON6A 3PYBA 3S4CA 2I07B 1TNZB 4V1RA 1FT1B 2DRRA 4AYPA 4AYRA 2RI8A 3DPYB 3S4AA 4EL8A 2WY8A 3H7LA 1KFGA 1O1TB 3W7UA 5GY3A 2H6FB 3HXCB 1SA4B 2D5JA 1WU5A 2WINB 3DRAB 2BB6A 3W5MA 1H13A 1TF4A 4ZG8A 3M78A 3H2WA 3QG0A 4GTOB 1KRFA 4CJ1A 3PZ3B 1C3DA 4LNVA 1V5DA 4CJ0A 2AFAA 1N4RB 3M76A 3PZ4B 2OKXA 1JCSB 2V8KA 1XWQA 3M7LA 2GH4A 3QPFA 4C1SA 4GTPB 1NXCA 1XWTA 2G02A 1KSDA 1WU6A 3M77A 2JF4A 3M7EA 2ZISB 3QT3A 2F0YB 3C72B 4L6XA 1G9JA 1LD7B 2GZ6A 2CQSA 1FBOA 3E33B 4GTRB 3M75A 5CZLA 5MEHA 1O79A 3RX8A 3QWTA 1H12A 4DOEA 1JCRB 4FXGB 1KZOB 3VXDA 1IA7A 1V5CA 3S9VA 3PZ1B 2R2LB 1FP3A 3S4BA 2NOJA 2JJBA 3RENA 4DODA 1LTXB 3GT5A 3SDRA 3M7CA 2VN4A 1X81B 1FMIA 3E37B 3GZKA 3RX7A 3QT9A 3KLSA 1RQ5A 1SQCA 2YIKA 2XWJB 1K72A 1HZFA 4GL3A 1GXNA 2Z07A 3EZ8A 3HXDB 1GXOA 3QRYA 2H6GB 3ACTA 3SFYB 2A73B 2JG0A 3Q73B 4YDEB 3SDTA 3SFXB 4GTMB 3H3KA 3M7BA 1DL2A 4L9PB 5KKBA 1N4PB 3RX5A 4XUVA 1G9GA 1NC5A 2SQCA 1TNOB 3EUVB 4TF4A 2F6DA 2FV1A 2D8LA 1LF9A 1H37A 1GLMA 2ZBLA 2VN7A 4V1SA 1NL4B 3HXEB 3GLYA 3S4DA 1H39A 3M71A 1D8EB 1R76A 1G6IA 1H54A 4QT9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZIR B;  5FO9 B;  4KKI A;  1H3A A;  1FT2 B;  4M76 A;  5FO7 B;  2ZIS B;  3RJ3 A;  1JCQ B;  2F0Y B;  3C72 B;  4YDO B;  1O1R B;  4GTQ B;  2G0D A;  3KQ4 A;  1H3C A;  1LD7 B;  1LD8 B;  3CU7 A;  3E33 B;  2PMV A;  4GTR B;  4D94 A;  1TN8 B;  4D4D A;  4MU9 A;  4GTT B;  3HXB B;  1H35 A;  1O79 A;  3EU5 B;  1N4Q B;  1O6H A;  3DSU B;  3DSX B;  5JPM B;  1N4S B;  2H6I B;  1JCR B;  2V8I A;  3K7X A;  3Q79 B;  4FXG B;  1UMP A;  1KZO B;  1W6J A;  2XQW A;  4BOJ A;  2BED B;  2V3P A;  3OED A;  1TNU B;  2H6H B;  4LNB B;  1S64 B;  1D8D B;  1GHQ A;  3PZ1 B;  2R2L B;  4ZH1 A;  2NOJ A;  4GTV B;  2V3N A;  1N9A B;  1LTX B;  2XWB B;  3PZ2 B;  3KSL B;  1DCE B;  1FPP B;  2GOX A;  5FOB B;  1QQF A;  1X81 B;  3E37 B;  3E34 B;  2WII B;  2I07 B;  3DSS B;  3KLS A;  1SQC A;  4BOK A;  1O5M B;  1TNZ B;  2XWJ B;  1HZF A;  4V1R A;  1GXN A;  1FT1 B;  1GSZ A;  3HXD B;  3HXF B;  1GXO A;  1TN6 B;  3DPY B;  1H3B A;  2H6G B;  4D4C A;  3DST B;  3SFY B;  2A73 B;  2WY8 A;  3SQC A;  3Q73 B;  4YDE B;  1TN7 B;  1O1T B;  3KSQ B;  4EHM B;  3SFX B;  4LNG B;  2V8J A;  1O6Q A;  2H6F B;  1S63 B;  4GTM B;  3HXC B;  3D5R A;  3DSV B;  3G6J B;  1H36 A;  1N4P B;  4L9P B;  4ONT A;  1SA4 B;  2PN5 A;  4FXK B;  1KZP B;  1W6K A;  2SQC A;  4ZRP A;  2WIN B;  1TNO B;  1NI1 B;  3EUV B;  4KKJ A;  3DRA B;  5AGD A;  2BB6 A;  2BBC A;  4D4A A;  3OXU A;  1O1S B;  1TNY B;  1N95 B;  4GTO B;  5JPN B;  3PZ3 B;  1C3D A;  1O6R A;  4GTS B;  3Q75 B;  4LNV A;  2WY7 A;  1H37 A;  1N4R B;  2B39 A;  2IEJ B;  3PZ4 B;  1GXM A;  4MBG B;  3E32 B;  4V1S A;  3E30 B;  1JCS B;  1NL4 B;  3Q7A B;  2V8K A;  1MZC B;  3HXE B;  5FO8 B;  4D4B A;  1TNB B;  1H39 A;  2BB5 A;  1D8E B;  1R76 A;  4ZRQ A;  1SA5 B;  3DSW B;  1QSJ A;  3Q7F B;  3D5S A;  1QBQ B;  3Q78 B;  4C1S A;  4GTP B;  2G02 A;  1N94 B; 
#chains in the Genus database with same CATH topology
 2ZIR B;  5FO9 B;  2FUZ A;  1V7V A;  1KWF A;  3RJ3 A;  4OJZ A;  1GAI A;  1WZZ A;  1LXM A;  1W3Y A;  3WIW A;  3X17 A;  3RRS A;  3K11 A;  2PMV A;  1G87 A;  3TF4 A;  1HX9 A;  4GTT B;  2FBA A;  1H35 A;  4CE7 A;  1HM2 A;  1HM3 A;  1KRE A;  1O6H A;  3AFJ A;  3DSU B;  2DRO A;  4FNV A;  2V8I A;  3K7X A;  3P5R A;  3Q79 B;  1GAH A;  2B4F A;  1W6J A;  2XQW A;  1FBW A;  1N7R A;  5EAT A;  1X1J A;  5ILH A;  1CEM A;  1TNU B;  4LNB B;  1D8D B;  1GHQ A;  1L2A A;  5GZK A;  4FJQ A;  5M7I A;  2QNO A;  3A3V A;  4JJJ A;  1KKT A;  1FPP B;  2GOX A;  1QQF A;  5IKH A;  3SAE A;  2WII B;  5JMD A;  3E6U A;  3DSS B;  3VSM A;  4J5T A;  4BOK A;  2ONG A;  3HXF B;  1AYX A;  3M74 A;  1TN6 B;  3WIQ A;  1EGU A;  1DOG A;  4D4C A;  1IA6 A;  3CIH A;  1F9G A;  3KSQ B;  4LNG B;  2V8J A;  1S63 B;  3D5R A;  3DSV B;  3G6J B;  4ONT A;  2PN5 A;  1FCE A;  1NI1 B;  4KKJ A;  2AHG A;  2P0V A;  2BBC A;  4ZH5 A;  3M73 A;  3OXU A;  1JS4 A;  1TNY B;  1N7O A;  1N95 B;  3T33 A;  3ACS A;  3WIR A;  1CB8 A;  2CQT A;  4GTS B;  3Q75 B;  1N22 A;  3G4F A;  1HXA A;  3QXF A;  4OK4 A;  2B39 A;  2IEJ B;  3M02 A;  1GXM A;  1HCU A;  4MBG B;  1RWG A;  3E32 B;  4GAX A;  3SDU A;  4DI5 A;  3E30 B;  5FO8 B;  3Q7A B;  1MZC B;  3E7J A;  4D4B A;  3M72 A;  1TNB B;  5IL8 A;  1UT9 A;  1GA2 A;  3W5N A;  1SA5 B;  3ANJ A;  1HXG A;  2EAC A;  1AGM A;  1CLC A;  4LIX A;  3QFZ A;  1OJO A;  4Z4J A;  1H3A A;  1FT2 B;  5FO7 B;  1N7P A;  2XFG A;  1JCQ B;  4YDO B;  1O1R B;  3KQ4 A;  1H14 A;  1H3C A;  3W7X A;  2RGK A;  3EQA A;  4Z4L A;  4D4D A;  3QDE A;  5CA3 A;  5DGQ A;  5IKA A;  4MU9 A;  2ZZR A;  1ULV A;  3EU5 B;  2FUQ A;  3W7T A;  1N4Q B;  1J0M A;  1HV6 A;  3DSX B;  4AYQ A;  2X03 A;  3WKH A;  2E24 A;  4NEI A;  5DGR A;  4Q88 A;  5CD2 A;  2BRP A;  2BED B;  2DRQ A;  2V3P A;  1VD5 A;  1RWA A;  4WVC A;  2AHF A;  1N9A B;  1RW9 A;  2XWB B;  3PZ2 B;  3KSL B;  2E22 A;  5IM1 A;  1DCE B;  1X9D A;  1KSC A;  3EU8 A;  1HMU A;  3RSY A;  5JMF A;  5ILD A;  3E34 B;  1IS9 A;  4TXT A;  2WCO A;  3VW5 A;  1O5M B;  1N23 A;  3QFY A;  1OJP A;  1GSZ A;  4F13 A;  1N1Z A;  5ILK A;  1H3B A;  3DST B;  4KTR A;  3SQC A;  3QSP A;  1TN7 B;  4EHM B;  1O6Q A;  3E73 A;  1XW2 A;  1H36 A;  3PYA A;  3WKG A;  4FXK B;  1KZP B;  1W6K A;  1X1I A;  4ZRP A;  5AGD A;  3WC3 A;  4WU0 A;  4D4A A;  3SDQ A;  1O1S B;  3P5P A;  1J0N A;  3D3I A;  5JPN B;  1WU4 A;  1FO3 A;  1O6R A;  1V7X A;  5GW7 A;  2WY7 A;  4WVA A;  2FUT A;  2EAD A;  1N24 A;  2WYN A;  4L0G A;  2EAB A;  1N7Q A;  2DRS A;  5E2J A;  2BB5 A;  1F9D A;  4ZRQ A;  4OZW A;  2NVP A;  5ILZ A;  3DSW B;  1QSJ A;  4WVB A;  3Q7F B;  3D5S A;  1QBQ B;  3Q78 B;  4KTP A;  4AYO A;  1F9O A;  3WUX A;  1N94 B;  3QXQ A;  3ANK A;  4KKI A;  4M76 A;  1N1B A;  5IK9 A;  4E1Y A;  1LF6 A;  1UG9 A;  3ANI A;  2G0D A;  4GTQ B;  1L1Y A;  4FUS A;  1LD8 B;  3CU7 A;  2A8Z A;  4D94 A;  1TN8 B;  2EAE A;  2RI9 A;  3SDV A;  3HXB B;  3WKI A;  3W7W A;  3N0F A;  5IL3 A;  3NNB A;  4Q2B A;  5EAU A;  1V7W A;  5JPM B;  1KS8 A;  1N4S B;  2H6I B;  3P2C A;  1UMP A;  2FV0 A;  5M7Y A;  1FO2 A;  4BOJ A;  1FAE A;  3OED A;  1C82 A;  2H6H B;  3PMM A;  1S64 B;  4ZH1 A;  1X1H A;  4GTV B;  2V3N A;  3W7S A;  4YCR A;  5FOB B;  4OZV A;  3ON6 A;  5EAS A;  3PYB A;  3WKF A;  5DHI A;  3S4C A;  2I07 B;  1TNZ B;  1HN0 A;  4V1R A;  2Q1F A;  4MMI A;  1FT1 B;  2DRR A;  4AYP A;  1N21 A;  4AYR A;  2RI8 A;  3DPY B;  3S4A A;  4EL8 A;  2WY8 A;  3H7L A;  1KFG A;  1O1T B;  1RWH A;  2BRW A;  5GY3 A;  3W7U A;  1QAZ A;  2H6F B;  3HXC B;  3LZ9 A;  1SA4 B;  1LOH A;  2D5J A;  1WU5 A;  2WIN B;  3DRA B;  2BB6 A;  5ILJ A;  1RWF A;  3W5M A;  1H13 A;  1TF4 A;  4ZG8 A;  3NFV A;  3M78 A;  3H2W A;  3QG0 A;  4GTO B;  1KRF A;  4CJ1 A;  3PZ3 B;  1C3D A;  3E80 A;  4LNV A;  1V5D A;  1OJN A;  4CJ0 A;  2AFA A;  1N4R B;  3M76 A;  3PZ4 B;  2OKX A;  1JCS B;  1I8Q A;  2V8K A;  1XWQ A;  3A0O A;  2ONH A;  3M7L A;  2GH4 A;  3QPF A;  4C1S A;  4GTP B;  1NXC A;  1XWT A;  2G02 A;  5IK6 A;  1KSD A;  3VSN A;  4OK2 A;  1WU6 A;  3M77 A;  2JF4 A;  3M7E A;  2ZIS B;  3QT3 A;  2F0Y B;  3C72 B;  4L6X A;  1G9J A;  1LD7 B;  2GZ6 A;  2CQS A;  1FBO A;  3E33 B;  1RWC A;  4GTR B;  3M75 A;  1HXC A;  1N7N A;  5CZL A;  1OJM A;  5MEH A;  1O79 A;  3M00 A;  3RX8 A;  3QWT A;  1H12 A;  1N20 A;  4DOE A;  1JCR B;  4FXG B;  1KZO B;  3VXD A;  1IA7 A;  1V5C A;  3S9V A;  3PZ1 B;  2R2L B;  1FP3 A;  3S4B A;  2NOJ A;  2JJB A;  2BRV X;  3REN A;  4DOD A;  1LTX B;  3GT5 A;  3SDR A;  3M7C A;  2VN4 A;  5IK0 A;  1X81 B;  1FMI A;  5C05 A;  3E37 B;  3AFL A;  3GZK A;  3RX7 A;  5DHK A;  3QT9 A;  3KLS A;  1RQ5 A;  1SQC A;  3M01 A;  2YIK A;  2XWJ B;  1K72 A;  1HZF A;  4GL3 A;  1GXN A;  2Z07 A;  3EZ8 A;  4MMH A;  1F1S A;  3HXD B;  1GXO A;  3QRY A;  2H6G B;  3ACT A;  5ILI A;  3SFY B;  2A73 B;  2JG0 A;  3Q73 B;  4YDE B;  3SDT A;  3SFX B;  4RNQ A;  4GTM B;  3H3K A;  3M7B A;  1DL2 A;  4L9P B;  5KKB A;  1N4P B;  3RX5 A;  4XUV A;  1G9G A;  1NC5 A;  2SQC A;  1TNO B;  1HMW A;  3EUV B;  5ILY A;  4TF4 A;  1LXK A;  3N0G A;  2F6D A;  2FV1 A;  4F10 A;  2D8L A;  1LF9 A;  1H37 A;  1GLM A;  2ZBL A;  2VN7 A;  4V1S A;  1NL4 B;  3HXE B;  3GLY A;  3S4D A;  1H39 A;  2J5C A;  3M71 A;  1D8E B;  1R76 A;  2WDA A;  3G4D A;  1G6I A;  1H54 A;  4QT9 A; 
#chains in the Genus database with same CATH homology
 2ZIR B;  5FO9 B;  2FUZ A;  1V7V A;  1KWF A;  3RJ3 A;  1GAI A;  1WZZ A;  3WIW A;  3X17 A;  3RRS A;  3K11 A;  2PMV A;  1G87 A;  3TF4 A;  4GTT B;  2FBA A;  1H35 A;  4CE7 A;  1KRE A;  1O6H A;  3AFJ A;  3DSU B;  2DRO A;  2V8I A;  3K7X A;  3P5R A;  3Q79 B;  1GAH A;  2B4F A;  1W6J A;  2XQW A;  1FBW A;  1CEM A;  1TNU B;  4LNB B;  1D8D B;  1GHQ A;  1L2A A;  5GZK A;  5M7I A;  2QNO A;  3A3V A;  4JJJ A;  1KKT A;  1FPP B;  2GOX A;  1QQF A;  3SAE A;  2WII B;  3E6U A;  3DSS B;  4BOK A;  4J5T A;  3HXF B;  1AYX A;  3M74 A;  1TN6 B;  3WIQ A;  1DOG A;  4D4C A;  1IA6 A;  3CIH A;  3KSQ B;  4LNG B;  2V8J A;  1S63 B;  3D5R A;  3DSV B;  3G6J B;  4ONT A;  2PN5 A;  1FCE A;  1NI1 B;  4KKJ A;  2AHG A;  2P0V A;  2BBC A;  4ZH5 A;  3M73 A;  3OXU A;  1JS4 A;  1TNY B;  1N95 B;  3T33 A;  3ACS A;  3WIR A;  2CQT A;  4GTS B;  3Q75 B;  3QXF A;  2B39 A;  2IEJ B;  1GXM A;  1HCU A;  4MBG B;  3E32 B;  3SDU A;  3E30 B;  5FO8 B;  3Q7A B;  1MZC B;  4D4B A;  3M72 A;  1TNB B;  1UT9 A;  1GA2 A;  3W5N A;  1SA5 B;  3ANJ A;  2EAC A;  1AGM A;  1CLC A;  4LIX A;  3QFZ A;  4Z4J A;  1H3A A;  1FT2 B;  5FO7 B;  2XFG A;  1JCQ B;  4YDO B;  1O1R B;  3KQ4 A;  1H14 A;  1H3C A;  3W7X A;  2RGK A;  3EQA A;  4Z4L A;  4D4D A;  3QDE A;  5CA3 A;  5DGQ A;  4MU9 A;  2ZZR A;  1ULV A;  3EU5 B;  3W7T A;  1N4Q B;  3DSX B;  4AYQ A;  3WKH A;  5DGR A;  4Q88 A;  5CD2 A;  2BED B;  2DRQ A;  2V3P A;  1VD5 A;  4WVC A;  2AHF A;  1N9A B;  2XWB B;  3PZ2 B;  3KSL B;  1DCE B;  1X9D A;  1KSC A;  3EU8 A;  3RSY A;  3E34 B;  1IS9 A;  4TXT A;  3VW5 A;  1O5M B;  3QFY A;  1GSZ A;  1H3B A;  3DST B;  4KTR A;  3SQC A;  3QSP A;  1TN7 B;  4EHM B;  1O6Q A;  3E73 A;  1XW2 A;  1H36 A;  3PYA A;  3WKG A;  4FXK B;  1KZP B;  1W6K A;  4ZRP A;  5AGD A;  3WC3 A;  4WU0 A;  4D4A A;  3SDQ A;  1O1S B;  3P5P A;  3D3I A;  5JPN B;  1WU4 A;  1FO3 A;  1O6R A;  1V7X A;  5GW7 A;  2WY7 A;  4WVA A;  2EAD A;  2WYN A;  4L0G A;  2EAB A;  2DRS A;  5E2J A;  2BB5 A;  1F9D A;  4ZRQ A;  2NVP A;  3DSW B;  1QSJ A;  4WVB A;  3Q7F B;  3D5S A;  1QBQ B;  3Q78 B;  4KTP A;  4AYO A;  1F9O A;  3WUX A;  1N94 B;  3QXQ A;  3ANK A;  4KKI A;  4M76 A;  1LF6 A;  1UG9 A;  3ANI A;  2G0D A;  4GTQ B;  1L1Y A;  4FUS A;  1LD8 B;  3CU7 A;  2A8Z A;  4D94 A;  1TN8 B;  2EAE A;  2RI9 A;  3SDV A;  3HXB B;  3WKI A;  3W7W A;  4Q2B A;  1V7W A;  5JPM B;  1KS8 A;  1N4S B;  2H6I B;  3P2C A;  1UMP A;  2FV0 A;  5M7Y A;  1FO2 A;  4BOJ A;  3OED A;  1FAE A;  3PMM A;  2H6H B;  1S64 B;  4ZH1 A;  4GTV B;  2V3N A;  3W7S A;  4YCR A;  5FOB B;  3WKF A;  3ON6 A;  3PYB A;  3S4C A;  2I07 B;  1TNZ B;  4V1R A;  1FT1 B;  2DRR A;  4AYP A;  4AYR A;  2RI8 A;  3DPY B;  3S4A A;  4EL8 A;  2WY8 A;  3H7L A;  1KFG A;  1O1T B;  3W7U A;  5GY3 A;  2H6F B;  3HXC B;  1SA4 B;  2D5J A;  1WU5 A;  2WIN B;  3DRA B;  2BB6 A;  3W5M A;  1H13 A;  1TF4 A;  4ZG8 A;  3M78 A;  3H2W A;  3QG0 A;  4GTO B;  1KRF A;  4CJ1 A;  3PZ3 B;  1C3D A;  4LNV A;  1V5D A;  4CJ0 A;  2AFA A;  1N4R B;  3M76 A;  3PZ4 B;  2OKX A;  1JCS B;  2V8K A;  1XWQ A;  3M7L A;  2GH4 A;  3QPF A;  4C1S A;  4GTP B;  1NXC A;  1XWT A;  2G02 A;  1KSD A;  1WU6 A;  3M77 A;  2JF4 A;  3M7E A;  2ZIS B;  3QT3 A;  2F0Y B;  3C72 B;  4L6X A;  1G9J A;  1LD7 B;  2GZ6 A;  2CQS A;  1FBO A;  3E33 B;  4GTR B;  3M75 A;  5CZL A;  5MEH A;  1O79 A;  3RX8 A;  3QWT A;  1H12 A;  4DOE A;  1JCR B;  4FXG B;  1KZO B;  3VXD A;  1IA7 A;  1V5C A;  3S9V A;  3PZ1 B;  2R2L B;  1FP3 A;  3S4B A;  2NOJ A;  2JJB A;  3REN A;  4DOD A;  1LTX B;  3GT5 A;  3SDR A;  3M7C A;  2VN4 A;  1X81 B;  1FMI A;  3E37 B;  3GZK A;  3RX7 A;  3QT9 A;  3KLS A;  1RQ5 A;  1SQC A;  2YIK A;  2XWJ B;  1K72 A;  1HZF A;  4GL3 A;  1GXN A;  2Z07 A;  3EZ8 A;  3HXD B;  1GXO A;  3QRY A;  2H6G B;  3ACT A;  3SFY B;  2A73 B;  2JG0 A;  3Q73 B;  4YDE B;  3SDT A;  3SFX B;  4GTM B;  3H3K A;  3M7B A;  1DL2 A;  4L9P B;  5KKB A;  1N4P B;  3RX5 A;  4XUV A;  1G9G A;  1NC5 A;  2SQC A;  1TNO B;  3EUV B;  4TF4 A;  2F6D A;  2FV1 A;  2D8L A;  1LF9 A;  1H37 A;  1GLM A;  2ZBL A;  2VN7 A;  4V1S A;  1NL4 B;  3HXE B;  3GLY A;  3S4D A;  1H39 A;  3M71 A;  1D8E B;  1R76 A;  1G6I A;  1H54 A;  4QT9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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