1SA5B

Rat protein farnesyltransferase complexed with fpp and bms-214662
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
407
structure length
407
Chain Sequence
PVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein farnesyltransferase/geranylgeranyltransferase type I
publication title Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity.
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Transferase
total genus 149
structure length 407
sequence length 407
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2004-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1sa5B00
1UMPA 3Q7AB 3Q73B 3E37B 4MBGB 1KZOB 1O6QA 3HXBB 4GTVB 4D4AA 3DSVB 4YDOB 4EHMB 3DRAB 3HXEB 4D4DA 4GTRB 2XQWA 4GTMB 2V8KA 2V8JA 4LNVA 4BOKA 1N4PB 3G6JB 1O6RA 3HXFB 1JCSB 2XWJB 3KLSA 1H39A 2WY8A 4LNGB 4GTSB 3DSSB 4L9PB 5FO7B 2XWBB 3DSXB 5AGDA 3OEDA 1NI1B 1W6JA 2H6FB 1O6HA 2V8IA 1GSZA 1FT1B 1N9AB 1TNOB 3C72B 2PMVA 1LTXB 1TN6B 3KSLB 4M76A 1R76A 1GXMA 1TNUB 1N4RB 4V1RA 1N95B 1JCRB 1W6KA 3DSWB 3SFYB 1TNBB 4FXGB 4C1SA 4LNBB 2BBCA 1SA5B 2H6HB 2A73B 3OXUA 4BOJA 3EU5B 3E30B 1O79A 5FOBB 3K7XA 3E32B 2BEDB 4GTPB 4ONTA 2BB6A 3PZ1B 1X81B 3HXCB 3SFXB 1D8EB 1H3CA 1DCEB 2F0YB 4GTQB 1N94B 4KKIA 2NOJA 4MU9A 3Q7FB 1TN8B 3E34B 1TNYB 3Q79B 3PZ4B 2ZISB 1NL4B 4GTTB 2WIIB 5JPMB 1H35A 3E33B 1GXOA 4D4CA 2ZIRB 1C3DA 3CU7A 4V1SA 5JPNB 2H6IB 2R2LB 2I07B 1FPPB 5FO9B 2PN5A 4ZRPA 1N4SB 1H3BA 1N4QB 1SA4B 1GXNA 1SQCA 1H3AA 4D94A 1FT2B 2B39A 1TNZB 1LD8B 3SQCA 4GTOB 2IEJB 3EUVB 1TN7B 1QBQB 3KSQB 5FO8B 3KQ4A 3DSUB 2BB5A 1O1SB 3Q78B 1MZCB 1O1TB 2WY7A 3DSTB 4KKJA 3RJ3A 1QSJA 1QQFA 1LD7B 3Q75B 2V3NA 1GHQA 3DPYB 1D8DB 4ZH1A 1O5MB 1HZFA 1O1RB 1JCQB 2GOXA 3HXDB 4YDEB 2WINB 1H37A 4D4BA 2G0DA 1S63B 4ZRQA 3D5RA 3D5SA 1H36A 2V3PA 1KZPB 3PZ2B 1S64B 3PZ3B 4FXKB 2H6GB 2SQCA 2G02A
chains in the Genus database with same CATH superfamily
1UMPA 1DOGA 4MBGB 1CB8A 1KZOB 3HXBB 3DSVB 4EHMB 5ILDA 2YIKA 1KFGA 1N22A 2V8JA 4BOKA 1QAZA 1XWQA 1O6RA 1N20A 3EZ8A 2WY8A 3DSSB 3H3KA 2DROA 1X1JA 1NI1B 1N7QA 3RX5A 3E7JA 1F1SA 3SDUA 1KS8A 4M76A 3WIRA 1TNUB 1RWFA 3PYBA 1XWTA 3ON6A 1JCRB 5ILKA 3DSWB 3SFYB 4C1SA 4FXGB 4F10A 4CJ0A 4Q2BA 1SA5B 2GH4A 1HM3A 4BOJA 4OZVA 3ACSA 3E30B 1O79A 3K7XA 1UT9A 2BEDB 3WKIA 3D3IA 4GTPB 2EACA 2D8LA 5DGQA 1FO2A 3SFXB 2FBAA 2D5JA 3G4DA 1H3CA 4MU9A 1LF9A 2VN4A 5IM1A 1TNYB 3M7CA 5DHIA 3QSPA 5ILYA 5JPMB 3QFZA 1GXOA 1F9DA 1C3DA 5ILHA 5JPNB 2I07B 1FPPB 5IL3A 3M00A 3TF4A 3RENA 1HN0A 1SA4B 3VXDA 4AYQA 1HM2A 1HXAA 3S4DA 1QBQB 2E22A 3DSUB 2BB5A 2WCOA 1O1TB 3WIQA 2J5CA 4KKJA 1QSJA 3LZ9A 4CE7A 4LIXA 1QQFA 4Q88A 1RWCA 2BRPA 4TF4A 3DPYB 4ZH1A 1J0NA 1OJNA 1O5MB 1HZFA 3QPFA 1O1RB 1KWFA 1JCQB 3NNBA 2GOXA 1DL2A 4YDEB 5C05A 4Z4JA 4D4BA 1FP3A 3T33A 3D5SA 3QXQA 1H36A 4MMHA 4D4CA 1I8QA 1XW2A 4DOEA 2Z07A 3DRAB 2JG0A 4GTRB 5IK6A 1AGMA 1V5DA 3VSMA 1H39A 2BRWA 1V7VA 4LNGB 5KKBA 2XWBB 3DSXB 4AYRA 2DRSA 3EQAA 1O6HA 2V8IA 1F9GA 1HMWA 4RNQA 1N24A 1N9AB 1TNOB 3C72B 3GZKA 1GLMA 5ILZA 1LTXB 1RWHA 5DGRA 3M76A 3AFJA 1R76A 1N95B 2FV1A 1G6IA 1W6KA 5ILJA 3QDEA 1N7NA 5DHKA 2EADA 1HV6A 2OKXA 2ONHA 3E32B 3N0GA 5MEHA 1H54A 2BB6A 1X81B 2AFAA 4GTQB 1DCEB 4E1YA 3Q7FB 1IA6A 1TN8B 3E34B 2ZISB 3P2CA 5JMFA 2WIIB 4L6XA 1H35A 3E33B 4WVBA 5CA3A 4WVCA 5GW7A 3CU7A 1V7WA 5EASA 5FO9B 1C82A 1N7PA 2FUZA 4ZRPA 4D94A 1H3BA 1GXNA 1H3AA 1FT2B 4FUSA 4FNVA 1TNZB 1OJMA 3WKGA 2IEJB 3M7LA 4J5TA 1WU5A 5IK9A 5FO8B 3KQ4A 3G4FA 1O1SB 3Q78B 5IKHA 3M02A 3H2WA 3M71A 3QG0A 3ANKA 5CD2A 2V3NA 3WKFA 1LXKA 4OK2A 2JF4A 2ZBLA 2ONGA 3CIHA 1J0MA 4WVAA 2WINB 5M7IA 1H37A 4ZRQA 2V3PA 1S64B 3PZ3B 2H6GB 1OJOA 1L1YA 2E24A 3QT9A 3Q73B 3A3VA 2QNOA 3E37B 5CZLA 2B4FA 3M72A 1O6QA 4YDOB 2GZ6A 2EAEA 5ILIA 2F6DA 1VD5A 3PMMA 1LOHA 2XQWA 3W7WA 3S4AA 4DI5A 1V7XA 3HXFB 3QRYA 3M75A 2XWJB 1KKTA 3KLSA 3E73A 3W7XA 2CQTA 1N7OA 4GTSB 3QFYA 2NVPA 1WU4A 3OEDA 1W6JA 2H6FB 4NEIA 3NFVA 3SAEA 1GSZA 1FT1B 1H13A 3GLYA 2JJBA 1IA7A 1IS9A 4CJ1A 4DODA 3KSLB 4WU0A 1GXMA 1N4RB 1RW9A 2FUQA 3RX8A 3S4BA 5JMDA 4OJZA 1TF4A 1TNBB 1K72A 3RRSA 5IKAA 2H6HB 1KSCA 5GY3A 5EATA 5FOBB 3SDTA 1H14A 4ONTA 2FV0A 3PZ1B 1RWAA 1D8EB 3W7UA 1N94B 2NOJA 1FBOA 3Q79B 1NL4B 3N0FA 3M74A 2RGKA 2ZZRA 2ZIRB 1WU6A 1FMIA 1HXGA 2H6IB 1N23A 2PN5A 1N4SB 1N4QB 1SQCA 3M01A 2B39A 3SQCA 1TN7B 4OZWA 3VSNA 3GT5A 4EL8A 4GAXA 1AYXA 2FUTA 5GZKA 1UG9A 1FCEA 1G9JA 2P0VA 3RX7A 2DRRA 2WY7A 3ACTA 2AHFA 2CQSA 3DSTB 1EGUA 3RJ3A 1G9GA 1LD7B 3A0OA 1HX9A 3Q75B 1GAHA 1G87A 1D8DB 1FO3A 3W7SA 1HCUA 3HXDB 1N1ZA 1ULVA 2WDAA 3ANJA 1S63B 3M78A 3QWTA 4L0GA 1KZPB 3PZ2B 4FXKB 2SQCA 2Q1FA 1V5CA 3Q7AB 4ZG8A 4GL3A 4GTVB 4D4AA 2VN7A 1GAIA 2XFGA 3HXEB 4D4DA 2DRQA 4GTMB 1N7RA 4JJJA 2EABA 2V8KA 5IL8A 3SDVA 4LNVA 1N4PB 3G6JB 1JCSB 1FAEA 3ANIA 1HXCA 1N1BA 5EAUA 4L9PB 5FO7B 1CEMA 5AGDA 1OJPA 4KTRA 4MMIA 5M7YA 3WKHA 2RI9A 2PMVA 1X1IA 3PYAA 3VW5A 1TN6B 4TXTA 4V1RA 4KTPA 3RSYA 1W3YA 4LNBB 4Z4LA 2BBCA 3M7BA 4FJQA 2A73B 3OXUA 3EU5B 1N21A 2X03A 1RWGA 1GA2A 5IK0A 4F13A 1L2AA 3H7LA 3HXCB 4KKIA 2F0YB 1FBWA 3PZ4B 4GTTB 3WIWA 2RI8A 1LXMA 1X9DA 4V1SA 2R2LB 1LF6A 3W5NA 3E80A 1F9OA 4YCRA 3SDQA 4AYOA 1X1HA 1LD8B 4GTOB 1H12A 3EUVB 3KSQB 3EU8A 1NXCA 1NC5A 3WC3A 4QT9A 1JS4A 1MZCB 3W7TA 2BRVX 3M77A 3K11A 1KRFA 3P5PA 4ZH5A 3X17A 2A8ZA 3SDRA 4AYPA 3S9VA 1KREA 3S4CA 3M73A 3QXFA 3M7EA 1GHQA 5E2JA 1HMUA 4XUVA 3E6UA 3P5RA 1RQ5A 3W5MA 3WUXA 1KSDA 2G0DA 3D5RA 1CLCA 4OK4A 2WYNA 1WZZA 3AFLA 3QT3A 2G02A 2AHGA
chains in the Genus database with same CATH topology
1UMPA 1DOGA 4MBGB 1KZOB 3HXBB 3DSVB 4EHMB 2YIKA 1KFGA 2V8JA 4BOKA 1XWQA 1O6RA 3EZ8A 2WY8A 3DSSB 3H3KA 2DROA 1NI1B 3RX5A 3SDUA 1KS8A 4M76A 3WIRA 1TNUB 3PYBA 1XWTA 3ON6A 1JCRB 3DSWB 3SFYB 4C1SA 4FXGB 4CJ0A 4Q2BA 1SA5B 2GH4A 4BOJA 3ACSA 3E30B 1O79A 3K7XA 1UT9A 2BEDB 3WKIA 3D3IA 4GTPB 2EACA 2D8LA 5DGQA 1FO2A 3SFXB 2FBAA 2D5JA 1H3CA 4MU9A 1LF9A 2VN4A 1TNYB 3M7CA 3QSPA 5JPMB 3QFZA 1GXOA 1F9DA 1C3DA 5JPNB 2I07B 1FPPB 3TF4A 3RENA 1SA4B 3VXDA 4AYQA 3S4DA 1QBQB 3DSUB 2BB5A 1O1TB 3WIQA 4KKJA 1QSJA 4CE7A 4LIXA 1QQFA 4Q88A 4TF4A 3DPYB 4ZH1A 1O5MB 1HZFA 3QPFA 1O1RB 1KWFA 1JCQB 2GOXA 1DL2A 4YDEB 4Z4JA 4D4BA 1FP3A 3T33A 3D5SA 3QXQA 1H36A 4D4CA 1XW2A 4DOEA 2Z07A 3DRAB 2JG0A 4GTRB 1AGMA 1V5DA 1H39A 1V7VA 4LNGB 5KKBA 2XWBB 3DSXB 4AYRA 2DRSA 3EQAA 1O6HA 2V8IA 1N9AB 1TNOB 3C72B 3GZKA 1GLMA 1LTXB 5DGRA 3M76A 3AFJA 1R76A 1N95B 2FV1A 1G6IA 1W6KA 3QDEA 2EADA 2OKXA 3E32B 5MEHA 1H54A 2BB6A 1X81B 2AFAA 4GTQB 1DCEB 3Q7FB 1IA6A 1TN8B 3E34B 2ZISB 3P2CA 2WIIB 4L6XA 1H35A 3E33B 4WVBA 5CA3A 4WVCA 5GW7A 3CU7A 1V7WA 5FO9B 2FUZA 4ZRPA 4D94A 1H3BA 1GXNA 1H3AA 1FT2B 4FUSA 1TNZB 3WKGA 2IEJB 3M7LA 4J5TA 1WU5A 5FO8B 3KQ4A 1O1SB 3Q78B 3H2WA 3M71A 3QG0A 3ANKA 5CD2A 2V3NA 3WKFA 2JF4A 2ZBLA 3CIHA 4WVAA 2WINB 5M7IA 1H37A 4ZRQA 2V3PA 1S64B 3PZ3B 2H6GB 1L1YA 3QT9A 3Q73B 3A3VA 2QNOA 3E37B 5CZLA 2B4FA 3M72A 1O6QA 4YDOB 2GZ6A 2EAEA 2F6DA 1VD5A 3PMMA 2XQWA 3W7WA 3S4AA 1V7XA 3HXFB 3QRYA 3M75A 2XWJB 1KKTA 3KLSA 3E73A 3W7XA 2CQTA 4GTSB 3QFYA 2NVPA 1WU4A 3OEDA 1W6JA 2H6FB 3SAEA 1GSZA 1FT1B 1H13A 3GLYA 2JJBA 1IA7A 1IS9A 4CJ1A 4DODA 3KSLB 4WU0A 1GXMA 1N4RB 3RX8A 3S4BA 1TF4A 1TNBB 1K72A 3RRSA 2H6HB 1KSCA 5GY3A 5FOBB 3SDTA 1H14A 4ONTA 2FV0A 3PZ1B 1D8EB 3W7UA 1N94B 2NOJA 1FBOA 3Q79B 1NL4B 3M74A 2RGKA 2ZZRA 2ZIRB 1WU6A 1FMIA 2H6IB 2PN5A 1N4SB 1N4QB 1SQCA 2B39A 3SQCA 1TN7B 3GT5A 4EL8A 1AYXA 5GZKA 1UG9A 1FCEA 1G9JA 2P0VA 3RX7A 2DRRA 2WY7A 3ACTA 2AHFA 2CQSA 3DSTB 3RJ3A 1G9GA 1LD7B 3Q75B 1GAHA 1G87A 1D8DB 1FO3A 3W7SA 1HCUA 3HXDB 1ULVA 3ANJA 1S63B 3M78A 3QWTA 4L0GA 1KZPB 3PZ2B 4FXKB 2SQCA 1V5CA 3Q7AB 4ZG8A 4GL3A 4GTVB 4D4AA 2VN7A 1GAIA 2XFGA 3HXEB 4D4DA 2DRQA 4GTMB 4JJJA 2EABA 2V8KA 3SDVA 4LNVA 1N4PB 3G6JB 1JCSB 1FAEA 3ANIA 4L9PB 5FO7B 1CEMA 5AGDA 4KTRA 5M7YA 3WKHA 2RI9A 2PMVA 3PYAA 3VW5A 1TN6B 4TXTA 4V1RA 4KTPA 3RSYA 4LNBB 4Z4LA 2BBCA 3M7BA 2A73B 3OXUA 3EU5B 1GA2A 1L2AA 3H7LA 3HXCB 4KKIA 2F0YB 1FBWA 3PZ4B 4GTTB 3WIWA 2RI8A 1X9DA 4V1SA 2R2LB 1LF6A 3W5NA 1F9OA 4YCRA 3SDQA 4AYOA 1LD8B 4GTOB 1H12A 3EUVB 3KSQB 3EU8A 1NXCA 1NC5A 3WC3A 4QT9A 1MZCB 1JS4A 3W7TA 3M77A 3K11A 1KRFA 3P5PA 4ZH5A 3X17A 2A8ZA 3SDRA 4AYPA 3S9VA 1KREA 3S4CA 3M73A 3QXFA 3M7EA 1GHQA 5E2JA 4XUVA 3E6UA 3P5RA 1RQ5A 3W5MA 3WUXA 1KSDA 2G0DA 3D5RA 1CLCA 2WYNA 1WZZA 3QT3A 2G02A 2AHGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UMP A;  3Q7A B;  3Q73 B;  3E37 B;  4MBG B;  1KZO B;  1O6Q A;  3HXB B;  4GTV B;  4D4A A;  3DSV B;  4YDO B;  4EHM B;  3DRA B;  3HXE B;  4D4D A;  4GTR B;  2XQW A;  4GTM B;  2V8K A;  2V8J A;  4LNV A;  4BOK A;  1N4P B;  3G6J B;  1O6R A;  3HXF B;  1JCS B;  2XWJ B;  3KLS A;  1H39 A;  2WY8 A;  4LNG B;  4GTS B;  3DSS B;  4L9P B;  5FO7 B;  2XWB B;  3DSX B;  5AGD A;  3OED A;  1NI1 B;  1W6J A;  2H6F B;  1O6H A;  2V8I A;  1GSZ A;  1FT1 B;  1N9A B;  1TNO B;  3C72 B;  2PMV A;  1LTX B;  1TN6 B;  3KSL B;  4M76 A;  1R76 A;  1GXM A;  1TNU B;  1N4R B;  4V1R A;  1N95 B;  1JCR B;  1W6K A;  3DSW B;  3SFY B;  1TNB B;  4FXG B;  4C1S A;  4LNB B;  2BBC A;  1SA5 B;  2H6H B;  2A73 B;  3OXU A;  4BOJ A;  3EU5 B;  3E30 B;  1O79 A;  5FOB B;  3K7X A;  3E32 B;  2BED B;  4GTP B;  4ONT A;  2BB6 A;  3PZ1 B;  1X81 B;  3HXC B;  3SFX B;  1D8E B;  1H3C A;  1DCE B;  2F0Y B;  4GTQ B;  1N94 B;  4KKI A;  2NOJ A;  4MU9 A;  3Q7F B;  1TN8 B;  3E34 B;  1TNY B;  3Q79 B;  3PZ4 B;  2ZIS B;  1NL4 B;  4GTT B;  2WII B;  5JPM B;  1H35 A;  3E33 B;  1GXO A;  4D4C A;  2ZIR B;  1C3D A;  3CU7 A;  4V1S A;  5JPN B;  2H6I B;  2R2L B;  2I07 B;  1FPP B;  5FO9 B;  2PN5 A;  4ZRP A;  1N4S B;  1H3B A;  1N4Q B;  1SA4 B;  1GXN A;  1SQC A;  1H3A A;  4D94 A;  1FT2 B;  2B39 A;  1TNZ B;  1LD8 B;  3SQC A;  4GTO B;  2IEJ B;  3EUV B;  1TN7 B;  1QBQ B;  3KSQ B;  5FO8 B;  3KQ4 A;  3DSU B;  2BB5 A;  1O1S B;  3Q78 B;  1MZC B;  1O1T B;  2WY7 A;  3DST B;  4KKJ A;  3RJ3 A;  1QSJ A;  1QQF A;  1LD7 B;  3Q75 B;  2V3N A;  1GHQ A;  3DPY B;  1D8D B;  4ZH1 A;  1O5M B;  1HZF A;  1O1R B;  1JCQ B;  2GOX A;  3HXD B;  4YDE B;  2WIN B;  1H37 A;  4D4B A;  2G0D A;  1S63 B;  4ZRQ A;  3D5R A;  3D5S A;  1H36 A;  2V3P A;  1KZP B;  3PZ2 B;  1S64 B;  3PZ3 B;  4FXK B;  2H6G B;  2SQC A;  2G02 A; 
#chains in the Genus database with same CATH topology
 1UMP A;  1DOG A;  4MBG B;  1CB8 A;  1KZO B;  3HXB B;  3DSV B;  4EHM B;  5ILD A;  2YIK A;  1KFG A;  1N22 A;  2V8J A;  4BOK A;  1QAZ A;  1XWQ A;  1O6R A;  1N20 A;  3EZ8 A;  2WY8 A;  3DSS B;  3H3K A;  2DRO A;  1X1J A;  1NI1 B;  1N7Q A;  3RX5 A;  3E7J A;  1F1S A;  3SDU A;  1KS8 A;  4M76 A;  3WIR A;  1TNU B;  1RWF A;  3PYB A;  1XWT A;  3ON6 A;  1JCR B;  5ILK A;  3DSW B;  3SFY B;  4C1S A;  4FXG B;  4F10 A;  4CJ0 A;  4Q2B A;  1SA5 B;  2GH4 A;  1HM3 A;  4BOJ A;  4OZV A;  3ACS A;  3E30 B;  1O79 A;  3K7X A;  1UT9 A;  2BED B;  3WKI A;  3D3I A;  4GTP B;  2EAC A;  2D8L A;  5DGQ A;  1FO2 A;  3SFX B;  2FBA A;  2D5J A;  3G4D A;  1H3C A;  4MU9 A;  1LF9 A;  2VN4 A;  5IM1 A;  1TNY B;  3M7C A;  5DHI A;  3QSP A;  5ILY A;  5JPM B;  3QFZ A;  1GXO A;  1F9D A;  1C3D A;  5ILH A;  5JPN B;  2I07 B;  1FPP B;  5IL3 A;  3M00 A;  3TF4 A;  3REN A;  1HN0 A;  1SA4 B;  3VXD A;  4AYQ A;  1HM2 A;  1HXA A;  3S4D A;  1QBQ B;  2E22 A;  3DSU B;  2BB5 A;  2WCO A;  1O1T B;  3WIQ A;  2J5C A;  4KKJ A;  1QSJ A;  3LZ9 A;  4CE7 A;  4LIX A;  1QQF A;  4Q88 A;  1RWC A;  2BRP A;  4TF4 A;  3DPY B;  4ZH1 A;  1J0N A;  1OJN A;  1O5M B;  1HZF A;  3QPF A;  1O1R B;  1KWF A;  1JCQ B;  3NNB A;  2GOX A;  1DL2 A;  4YDE B;  5C05 A;  4Z4J A;  4D4B A;  1FP3 A;  3T33 A;  3D5S A;  3QXQ A;  1H36 A;  4MMH A;  4D4C A;  1I8Q A;  1XW2 A;  4DOE A;  2Z07 A;  3DRA B;  2JG0 A;  4GTR B;  5IK6 A;  1AGM A;  1V5D A;  3VSM A;  1H39 A;  2BRW A;  1V7V A;  4LNG B;  5KKB A;  2XWB B;  3DSX B;  4AYR A;  2DRS A;  3EQA A;  1O6H A;  2V8I A;  1F9G A;  1HMW A;  4RNQ A;  1N24 A;  1N9A B;  1TNO B;  3C72 B;  3GZK A;  1GLM A;  5ILZ A;  1LTX B;  1RWH A;  5DGR A;  3M76 A;  3AFJ A;  1R76 A;  1N95 B;  2FV1 A;  1G6I A;  1W6K A;  5ILJ A;  3QDE A;  1N7N A;  5DHK A;  2EAD A;  1HV6 A;  2OKX A;  2ONH A;  3E32 B;  3N0G A;  5MEH A;  1H54 A;  2BB6 A;  1X81 B;  2AFA A;  4GTQ B;  1DCE B;  4E1Y A;  3Q7F B;  1IA6 A;  1TN8 B;  3E34 B;  2ZIS B;  3P2C A;  5JMF A;  2WII B;  4L6X A;  1H35 A;  3E33 B;  4WVB A;  5CA3 A;  4WVC A;  5GW7 A;  3CU7 A;  1V7W A;  5EAS A;  5FO9 B;  1C82 A;  1N7P A;  2FUZ A;  4ZRP A;  4D94 A;  1H3B A;  1GXN A;  1H3A A;  1FT2 B;  4FUS A;  4FNV A;  1TNZ B;  1OJM A;  3WKG A;  2IEJ B;  3M7L A;  4J5T A;  1WU5 A;  5IK9 A;  5FO8 B;  3KQ4 A;  3G4F A;  1O1S B;  3Q78 B;  5IKH A;  3M02 A;  3H2W A;  3M71 A;  3QG0 A;  3ANK A;  5CD2 A;  2V3N A;  3WKF A;  1LXK A;  4OK2 A;  2JF4 A;  2ZBL A;  2ONG A;  3CIH A;  1J0M A;  4WVA A;  2WIN B;  5M7I A;  1H37 A;  4ZRQ A;  2V3P A;  1S64 B;  3PZ3 B;  2H6G B;  1OJO A;  1L1Y A;  2E24 A;  3QT9 A;  3Q73 B;  3A3V A;  2QNO A;  3E37 B;  5CZL A;  2B4F A;  3M72 A;  1O6Q A;  4YDO B;  2GZ6 A;  2EAE A;  5ILI A;  2F6D A;  1VD5 A;  3PMM A;  1LOH A;  2XQW A;  3W7W A;  3S4A A;  4DI5 A;  1V7X A;  3HXF B;  3QRY A;  3M75 A;  2XWJ B;  1KKT A;  3KLS A;  3E73 A;  3W7X A;  2CQT A;  1N7O A;  4GTS B;  3QFY A;  2NVP A;  1WU4 A;  3OED A;  1W6J A;  2H6F B;  4NEI A;  3NFV A;  3SAE A;  1GSZ A;  1FT1 B;  1H13 A;  3GLY A;  2JJB A;  1IA7 A;  1IS9 A;  4CJ1 A;  4DOD A;  3KSL B;  4WU0 A;  1GXM A;  1N4R B;  1RW9 A;  2FUQ A;  3RX8 A;  3S4B A;  5JMD A;  4OJZ A;  1TF4 A;  1TNB B;  1K72 A;  3RRS A;  5IKA A;  2H6H B;  1KSC A;  5GY3 A;  5EAT A;  5FOB B;  3SDT A;  1H14 A;  4ONT A;  2FV0 A;  3PZ1 B;  1RWA A;  1D8E B;  3W7U A;  1N94 B;  2NOJ A;  1FBO A;  3Q79 B;  1NL4 B;  3N0F A;  3M74 A;  2RGK A;  2ZZR A;  2ZIR B;  1WU6 A;  1FMI A;  1HXG A;  2H6I B;  1N23 A;  2PN5 A;  1N4S B;  1N4Q B;  1SQC A;  3M01 A;  2B39 A;  3SQC A;  1TN7 B;  4OZW A;  3VSN A;  3GT5 A;  4EL8 A;  4GAX A;  1AYX A;  2FUT A;  5GZK A;  1UG9 A;  1FCE A;  1G9J A;  2P0V A;  3RX7 A;  2DRR A;  2WY7 A;  3ACT A;  2AHF A;  2CQS A;  3DST B;  1EGU A;  3RJ3 A;  1G9G A;  1LD7 B;  3A0O A;  1HX9 A;  3Q75 B;  1GAH A;  1G87 A;  1D8D B;  1FO3 A;  3W7S A;  1HCU A;  3HXD B;  1N1Z A;  1ULV A;  2WDA A;  3ANJ A;  1S63 B;  3M78 A;  3QWT A;  4L0G A;  1KZP B;  3PZ2 B;  4FXK B;  2SQC A;  2Q1F A;  1V5C A;  3Q7A B;  4ZG8 A;  4GL3 A;  4GTV B;  4D4A A;  2VN7 A;  1GAI A;  2XFG A;  3HXE B;  4D4D A;  2DRQ A;  4GTM B;  1N7R A;  4JJJ A;  2EAB A;  2V8K A;  5IL8 A;  3SDV A;  4LNV A;  1N4P B;  3G6J B;  1JCS B;  1FAE A;  3ANI A;  1HXC A;  1N1B A;  5EAU A;  4L9P B;  5FO7 B;  1CEM A;  5AGD A;  1OJP A;  4KTR A;  4MMI A;  5M7Y A;  3WKH A;  2RI9 A;  2PMV A;  1X1I A;  3PYA A;  3VW5 A;  1TN6 B;  4TXT A;  4V1R A;  4KTP A;  3RSY A;  1W3Y A;  4LNB B;  4Z4L A;  2BBC A;  3M7B A;  4FJQ A;  2A73 B;  3OXU A;  3EU5 B;  1N21 A;  2X03 A;  1RWG A;  1GA2 A;  5IK0 A;  4F13 A;  1L2A A;  3H7L A;  3HXC B;  4KKI A;  2F0Y B;  1FBW A;  3PZ4 B;  4GTT B;  3WIW A;  2RI8 A;  1LXM A;  1X9D A;  4V1S A;  2R2L B;  1LF6 A;  3W5N A;  3E80 A;  1F9O A;  4YCR A;  3SDQ A;  4AYO A;  1X1H A;  1LD8 B;  4GTO B;  1H12 A;  3EUV B;  3KSQ B;  3EU8 A;  1NXC A;  1NC5 A;  3WC3 A;  4QT9 A;  1JS4 A;  1MZC B;  3W7T A;  2BRV X;  3M77 A;  3K11 A;  1KRF A;  3P5P A;  4ZH5 A;  3X17 A;  2A8Z A;  3SDR A;  4AYP A;  3S9V A;  1KRE A;  3S4C A;  3M73 A;  3QXF A;  3M7E A;  1GHQ A;  5E2J A;  1HMU A;  4XUV A;  3E6U A;  3P5R A;  1RQ5 A;  3W5M A;  3WUX A;  1KSD A;  2G0D A;  3D5R A;  1CLC A;  4OK4 A;  2WYN A;  1WZZ A;  3AFL A;  3QT3 A;  2G02 A;  2AHG A; 
#chains in the Genus database with same CATH homology
 1UMP A;  1DOG A;  4MBG B;  1KZO B;  3HXB B;  3DSV B;  4EHM B;  2YIK A;  1KFG A;  2V8J A;  4BOK A;  1XWQ A;  1O6R A;  3EZ8 A;  2WY8 A;  3DSS B;  3H3K A;  2DRO A;  1NI1 B;  3RX5 A;  3SDU A;  1KS8 A;  4M76 A;  3WIR A;  1TNU B;  3PYB A;  1XWT A;  3ON6 A;  1JCR B;  3DSW B;  3SFY B;  4C1S A;  4FXG B;  4CJ0 A;  4Q2B A;  1SA5 B;  2GH4 A;  4BOJ A;  3ACS A;  3E30 B;  1O79 A;  3K7X A;  1UT9 A;  2BED B;  3WKI A;  3D3I A;  4GTP B;  2EAC A;  2D8L A;  5DGQ A;  1FO2 A;  3SFX B;  2FBA A;  2D5J A;  1H3C A;  4MU9 A;  1LF9 A;  2VN4 A;  1TNY B;  3M7C A;  3QSP A;  5JPM B;  3QFZ A;  1GXO A;  1F9D A;  1C3D A;  5JPN B;  2I07 B;  1FPP B;  3TF4 A;  3REN A;  1SA4 B;  3VXD A;  4AYQ A;  3S4D A;  1QBQ B;  3DSU B;  2BB5 A;  1O1T B;  3WIQ A;  4KKJ A;  1QSJ A;  4CE7 A;  4LIX A;  1QQF A;  4Q88 A;  4TF4 A;  3DPY B;  4ZH1 A;  1O5M B;  1HZF A;  3QPF A;  1O1R B;  1KWF A;  1JCQ B;  2GOX A;  1DL2 A;  4YDE B;  4Z4J A;  4D4B A;  1FP3 A;  3T33 A;  3D5S A;  3QXQ A;  1H36 A;  4D4C A;  1XW2 A;  4DOE A;  2Z07 A;  3DRA B;  2JG0 A;  4GTR B;  1AGM A;  1V5D A;  1H39 A;  1V7V A;  4LNG B;  5KKB A;  2XWB B;  3DSX B;  4AYR A;  2DRS A;  3EQA A;  1O6H A;  2V8I A;  1N9A B;  1TNO B;  3C72 B;  3GZK A;  1GLM A;  1LTX B;  5DGR A;  3M76 A;  3AFJ A;  1R76 A;  1N95 B;  2FV1 A;  1G6I A;  1W6K A;  3QDE A;  2EAD A;  2OKX A;  3E32 B;  5MEH A;  1H54 A;  2BB6 A;  1X81 B;  2AFA A;  4GTQ B;  1DCE B;  3Q7F B;  1IA6 A;  1TN8 B;  3E34 B;  2ZIS B;  3P2C A;  2WII B;  4L6X A;  1H35 A;  3E33 B;  4WVB A;  5CA3 A;  4WVC A;  5GW7 A;  3CU7 A;  1V7W A;  5FO9 B;  2FUZ A;  4ZRP A;  4D94 A;  1H3B A;  1GXN A;  1H3A A;  1FT2 B;  4FUS A;  1TNZ B;  3WKG A;  2IEJ B;  3M7L A;  4J5T A;  1WU5 A;  5FO8 B;  3KQ4 A;  1O1S B;  3Q78 B;  3H2W A;  3M71 A;  3QG0 A;  3ANK A;  5CD2 A;  2V3N A;  3WKF A;  2JF4 A;  2ZBL A;  3CIH A;  4WVA A;  2WIN B;  5M7I A;  1H37 A;  4ZRQ A;  2V3P A;  1S64 B;  3PZ3 B;  2H6G B;  1L1Y A;  3QT9 A;  3Q73 B;  3A3V A;  2QNO A;  3E37 B;  5CZL A;  2B4F A;  3M72 A;  1O6Q A;  4YDO B;  2GZ6 A;  2EAE A;  2F6D A;  1VD5 A;  3PMM A;  2XQW A;  3W7W A;  3S4A A;  1V7X A;  3HXF B;  3QRY A;  3M75 A;  2XWJ B;  1KKT A;  3KLS A;  3E73 A;  3W7X A;  2CQT A;  4GTS B;  3QFY A;  2NVP A;  1WU4 A;  3OED A;  1W6J A;  2H6F B;  3SAE A;  1GSZ A;  1FT1 B;  1H13 A;  3GLY A;  2JJB A;  1IA7 A;  1IS9 A;  4CJ1 A;  4DOD A;  3KSL B;  4WU0 A;  1GXM A;  1N4R B;  3RX8 A;  3S4B A;  1TF4 A;  1TNB B;  1K72 A;  3RRS A;  2H6H B;  1KSC A;  5GY3 A;  5FOB B;  3SDT A;  1H14 A;  4ONT A;  2FV0 A;  3PZ1 B;  1D8E B;  3W7U A;  1N94 B;  2NOJ A;  1FBO A;  3Q79 B;  1NL4 B;  3M74 A;  2RGK A;  2ZZR A;  2ZIR B;  1WU6 A;  1FMI A;  2H6I B;  2PN5 A;  1N4S B;  1N4Q B;  1SQC A;  2B39 A;  3SQC A;  1TN7 B;  3GT5 A;  4EL8 A;  1AYX A;  5GZK A;  1UG9 A;  1FCE A;  1G9J A;  2P0V A;  3RX7 A;  2DRR A;  2WY7 A;  3ACT A;  2AHF A;  2CQS A;  3DST B;  3RJ3 A;  1G9G A;  1LD7 B;  3Q75 B;  1GAH A;  1G87 A;  1D8D B;  1FO3 A;  3W7S A;  1HCU A;  3HXD B;  1ULV A;  3ANJ A;  1S63 B;  3M78 A;  3QWT A;  4L0G A;  1KZP B;  3PZ2 B;  4FXK B;  2SQC A;  1V5C A;  3Q7A B;  4ZG8 A;  4GL3 A;  4GTV B;  4D4A A;  2VN7 A;  1GAI A;  2XFG A;  3HXE B;  4D4D A;  2DRQ A;  4GTM B;  4JJJ A;  2EAB A;  2V8K A;  3SDV A;  4LNV A;  1N4P B;  3G6J B;  1JCS B;  1FAE A;  3ANI A;  4L9P B;  5FO7 B;  1CEM A;  5AGD A;  4KTR A;  5M7Y A;  3WKH A;  2RI9 A;  2PMV A;  3PYA A;  3VW5 A;  1TN6 B;  4TXT A;  4V1R A;  4KTP A;  3RSY A;  4LNB B;  4Z4L A;  2BBC A;  3M7B A;  2A73 B;  3OXU A;  3EU5 B;  1GA2 A;  1L2A A;  3H7L A;  3HXC B;  4KKI A;  2F0Y B;  1FBW A;  3PZ4 B;  4GTT B;  3WIW A;  2RI8 A;  1X9D A;  4V1S A;  2R2L B;  1LF6 A;  3W5N A;  1F9O A;  4YCR A;  3SDQ A;  4AYO A;  1LD8 B;  4GTO B;  1H12 A;  3EUV B;  3KSQ B;  3EU8 A;  1NXC A;  1NC5 A;  3WC3 A;  4QT9 A;  1MZC B;  1JS4 A;  3W7T A;  3M77 A;  3K11 A;  1KRF A;  3P5P A;  4ZH5 A;  3X17 A;  2A8Z A;  3SDR A;  4AYP A;  3S9V A;  1KRE A;  3S4C A;  3M73 A;  3QXF A;  3M7E A;  1GHQ A;  5E2J A;  4XUV A;  3E6U A;  3P5R A;  1RQ5 A;  3W5M A;  3WUX A;  1KSD A;  2G0D A;  3D5R A;  1CLC A;  2WYN A;  1WZZ A;  3QT3 A;  2G02 A;  2AHG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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