1SAFA

High resolution solution nmr structure of the oligomerization domain of p53 by multi-dimensional nmr (sad structures)
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
42
structure length
42
Chain Sequence
KKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Refined solution structure of the oligomerization domain of the tumour suppressor p53.
pubmed doi rcsb
molecule tags Anti-oncogene
molecule keywords TUMOR SUPPRESSOR P53
total genus 9
structure length 42
sequence length 42
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 1995-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07710 P53_tetramer P53 tetramerisation motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.170.10 Few Secondary Structures Irregular p53, subunit A p53-like tetramerisation domain 1safA00
1OLHA 2KBYA 3SAKA 2MW4A 2WTTA 4A9ZA 5HOBA 2WQIA 3ZY1A 1SAKA 5HOCA 1OLGA 1SAEA 1SAFA 1SALA
chains in the Genus database with same CATH superfamily
1OLHA 2KBYA 3SAKA 2MW4A 2WTTA 4A9ZA 5HOBA 2WQIA 3ZY1A 1SAKA 5HOCA 1OLGA 1SAEA 1SAFA 1SALA
chains in the Genus database with same CATH topology
1OLHA 2KBYA 3SAKA 2MW4A 2WTTA 4A9ZA 5HOBA 2WQIA 3ZY1A 1SAKA 5HOCA 1OLGA 1SAEA 1SAFA 1SALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OLH A;  2KBY A;  3SAK A;  2MW4 A;  2WTT A;  4A9Z A;  5HOB A;  2WQI A;  3ZY1 A;  1SAK A;  5HOC A;  1OLG A;  1SAE A;  1SAF A;  1SAL A; 
#chains in the Genus database with same CATH topology
 1OLH A;  2KBY A;  3SAK A;  2MW4 A;  2WTT A;  4A9Z A;  5HOB A;  2WQI A;  3ZY1 A;  1SAK A;  5HOC A;  1OLG A;  1SAE A;  1SAF A;  1SAL A; 
#chains in the Genus database with same CATH homology
 1OLH A;  2KBY A;  3SAK A;  2MW4 A;  2WTT A;  4A9Z A;  5HOB A;  2WQI A;  3ZY1 A;  1SAK A;  5HOC A;  1OLG A;  1SAE A;  1SAF A;  1SAL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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