1SGPI

Ala 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTAEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
pubmed rcsb
molecule keywords STREPTOMYCES GRISEUS PROTEINASE B
molecule tags Complex (serine protease/inhibitor)
source organism Streptomyces griseus
total genus 12
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1995-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1sgpI00
1M8BA 2M5XA 1FYBA 1MT1A 1SGEI 1CGII 3HH2C 2V53A 1CT4I 1CT0I 2WCYA 2B0UC 1IY6A 1M8CA 1DS3I 1TIHA 1Y1BA 2P6AC 3SGBI 2KMRA 2SGEI 1CE3A 2KCXA 3QTLD 1IW4A 1OMUA 2JXDA 4HGUA 1CHOI 1LR7A 1PPFI 2KMQA 2NU2I 1KMAA 1NUBA 1AN1I 1N13A 1LR8A 1PJUA 1R0RI 2JYYA 2ERWA 1Z7KB 1SGDI 1SGNI 3TJQA 1CSOI 1TURA 1YTPA 1PCEA 1BMOA 2F3CI 2QQDA 2GKRI 3SEKC 1DS2I 1HJAI 2NU0I 2GKVA 2BUSA 1UVGA 2KMPA 3B4VC 1SGQI 2JZMA 4OVOA 1UVFA 2KMOA 2SGFI 1YU6C 1OMTA 1UUCA 1TUSA 5JHWC 2XRCA 2OVOA 2NU1I 2NU4I 2QQCA 2LEOA 2SGQI 4SGBI 2SGDI 2GKTI 1HDLA 1SGYI 2N71A 1LR9A 1SGPI 4GI3C 1TGSI 2SGPI 2NU3I 1OYVI 1TBQR 1Y1CA 1TBRR 1BUSA 1CGJI 1IY5A 1OVOA 2N52A 1H0ZA 2ARPF 3OVOA 3SGQI 1SGRI 2N17A 1HPTA 5DAEA 1CT2I
chains in the Genus database with same CATH superfamily
1M8BA 2FNFX 1W4RA 3TO9A 2K9HA 2M5XA 3TO6A 3R5DA 1FYBA 2V1CA 2OU2A 2X52A 1MT1A 5HQ8A 4B6DA 1K7VA 3UGIA 7WGAA 1SGEI 1XA6A 5J8FA 1MJAA 2ORWA 1CGII 2ORVA 1MJBA 1ULNA 3HH2C 2V53A 1CT4I 2ENNA 3TOAA 5HI7A 4E1PA 1CT0I 5EX0A 2WCYA 3E2IA 5FUYA 2B0UC 1IY6A 1P9ZA 2B8TA 2DIPA 2Y0MA 1M8CA 1DS3I 1TIHA 1V1HA 1WKXA 2CWGA 3R5AA 5FUXA 3UEYA 1Q9BA 1Y1BA 2P6AC 3SGBI 1V1IA 1S20A 2KMRA 2SGEI 2WVJA 2E73A 1CE3A 1ULKA 2KCXA 3QWPA 3QTLD 1IW4A 1OMUA 2JXDA 3E59A 4HGUA 1CHOI 1LR7A 1PPFI 2UVOA 4UXJA 2KMQA 2NU2I 2UZ3A 1NUBA 1TBNA 1AN1I 1KMAA 1KBFA 3R5CA 4A24A 1N13A 1LR8A 1MJ9A 1PJUA 3UFFA 3R5BA 1VDDA 1Y8FA 1R0RI 2JYYA 2ERWA 2DB6A 1ULMA 1Z7KB 2CJSC 2RIJA 4UXHA 1SGDI 1SGNI 3OXLA 3PDNA 5E3RA 1XX6A 3BJIA 3TJQA 1CSOI 1PTQA 2CWHA 2QQEA 1TURA 1YTPA 2PQ8A 5FUWA 1PCEA 1BMOA 1PTRA 2W0TA 3UGDA 1K7TA 3GOXA 1Z2IA 2QQ0A 4L9MA 1X4SA 1RFHA 2YQPA 2F3CI 2QQDA 1HEVA 2GKRI 3SEKC 1WGTA 1DS2I 2DKVA 2X3TA 1HJAI 2NU0I 3FSYA 2GKVA 2JW6A 2BUSA 4E1RA 3MEKA 1UVGA 1P9GA 1W3SA 2J9RA 1WTJA 2KMPA 3B4VC 1SGQI 1TOTA 1FY7A 2A20A 2JZMA 3KY9A 1UVFA 4MPIA 4OVOA 2OD1A 2KMOA 2N1AB 2SGFI 4UXIA 4DNCA 1YU6C 1U5KA 1OMTA 1UUCA 2LUYA 1TUSA 5JHWC 2XRCA 4JCVE 3UEJA 1X74A 2LB7A 2OVOA 3UOEA 3D00A 2ODDA 2NU1I 2CWFA 2NU4I 3UGLA 1K7UA 2QQCA 2OZUA 2ROWA 2V1CC 3RU0A 3FC3A 3QAHA 2LEOA 2SGQI 2ELIA 3OL0A 4SGBI 2VRWB 1KBEA 2SGDI 1R79A 2GKTI 4FKDA 5CCLA 1FAQA 2YUUA 1HDLA 1SGYI 2J87A 2GIVA 3OXFA 3OXGA 1WGCA 2L7XA 9WGAA 2N71A 1LR9A 1SGPI 4GI3C 1TGSI 2SGPI 2JA1A 2NU3I 1OYVI 3CXLA 5E3PA 1FARA 1TBQR 1Y1CA 5J8CA 1TBRR 1XBTA 2ENZA 2GVIA 3VE5A 2WGCA 1BUSA 1UHAA 2RC4A 5CCMA 3TOBA 2L8EA 1CGJI 1IY5A 1OVOA 1TBOA 2N52A 3TO7A 1H0ZA 4WP4A 3VDUA 2ARPF 3OVOA 3SGQI 1SGRI 3FSXA 5EX3A 3VDPA 4AMLA 2N17A 1NXUA 2QPOA 1HPTA 2E5RA 5DAEA 1CT2I 5FUVA 5E3QA
chains in the Genus database with same CATH topology
1M8BA 2FNFX 1W4RA 2K9HA 2M5XA 1FYBA 2V1CA 1MT1A 5HQ8A 4B6DA 3UGIA 1SGEI 1XA6A 2ORWA 1CGII 2ORVA 3HH2C 2V53A 1CT4I 2ENNA 4E1PA 5HI7A 1CT0I 5EX0A 2WCYA 3E2IA 5FUYA 2B0UC 1IY6A 2B8TA 2DIPA 1M8CA 1DS3I 1TIHA 1V1HA 5FUXA 3UEYA 1Y1BA 2P6AC 3SGBI 1V1IA 2KMRA 2SGEI 2WVJA 2E73A 1CE3A 2KCXA 3QWPA 3QTLD 1IW4A 1OMUA 2JXDA 3E59A 4HGUA 1CHOI 1LR7A 1PPFI 4UXJA 2KMQA 2NU2I 2UZ3A 1NUBA 1TBNA 1AN1I 1KMAA 1KBFA 4A24A 1N13A 1LR8A 1PJUA 3UFFA 1VDDA 1Y8FA 1R0RI 2JYYA 2ERWA 2DB6A 4UXHA 1Z7KB 2CJSC 1SGDI 1SGNI 3OXLA 3PDNA 1XX6A 3BJIA 3TJQA 1CSOI 1PTQA 2QQEA 1TURA 1YTPA 5FUWA 1PCEA 1BMOA 1PTRA 2W0TA 3UGDA 3GOXA 2QQ0A 4L9MA 1X4SA 1RFHA 2YQPA 2F3CI 2QQDA 2GKRI 3SEKC 1DS2I 1HJAI 2NU0I 2GKVA 2JW6A 2BUSA 4E1RA 3MEKA 1UVGA 2J9RA 1W3SA 2KMPA 3B4VC 1SGQI 1TOTA 2A20A 2JZMA 3KY9A 1UVFA 4OVOA 2OD1A 2KMOA 2N1AB 2SGFI 4UXIA 1YU6C 1U5KA 1OMTA 1UUCA 2LUYA 1TUSA 5JHWC 2XRCA 4JCVE 3UEJA 1X74A 2OVOA 3D00A 2ODDA 2NU1I 2NU4I 3UGLA 2ROWA 2QQCA 2V1CC 3RU0A 3FC3A 2LEOA 2SGQI 2ELIA 3OL0A 4SGBI 2VRWB 1KBEA 2SGDI 1R79A 2GKTI 4FKDA 5CCLA 1FAQA 2YUUA 1HDLA 1SGYI 2J87A 3OXGA 3OXFA 2L7XA 2N71A 1LR9A 1SGPI 4GI3C 1TGSI 2SGPI 2JA1A 2NU3I 1OYVI 3CXLA 1FARA 1TBQR 1Y1CA 1TBRR 1XBTA 2ENZA 2GVIA 3VE5A 1BUSA 5CCMA 2L8EA 1CGJI 1IY5A 1OVOA 1TBOA 2N52A 1H0ZA 3VDUA 2ARPF 3OVOA 3SGQI 1SGRI 3VDPA 5EX3A 2N17A 2QPOA 1HPTA 2E5RA 5DAEA 1CT2I 5FUVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M8B A;  2M5X A;  1FYB A;  1MT1 A;  1SGE I;  1CGI I;  3HH2 C;  2V53 A;  1CT4 I;  1CT0 I;  2WCY A;  2B0U C;  1IY6 A;  1M8C A;  1DS3 I;  1TIH A;  1Y1B A;  2P6A C;  3SGB I;  2KMR A;  2SGE I;  1CE3 A;  2KCX A;  3QTL D;  1IW4 A;  1OMU A;  2JXD A;  4HGU A;  1CHO I;  1LR7 A;  1PPF I;  2KMQ A;  2NU2 I;  1KMA A;  1NUB A;  1AN1 I;  1N13 A;  1LR8 A;  1PJU A;  1R0R I;  2JYY A;  2ERW A;  1Z7K B;  1SGD I;  1SGN I;  3TJQ A;  1CSO I;  1TUR A;  1YTP A;  1PCE A;  1BMO A;  2F3C I;  2QQD A;  2GKR I;  3SEK C;  1DS2 I;  1HJA I;  2NU0 I;  2GKV A;  2BUS A;  1UVG A;  2KMP A;  3B4V C;  1SGQ I;  2JZM A;  4OVO A;  1UVF A;  2KMO A;  2SGF I;  1YU6 C;  1OMT A;  1UUC A;  1TUS A;  5JHW C;  2XRC A;  2OVO A;  2NU1 I;  2NU4 I;  2QQC A;  2LEO A;  2SGQ I;  4SGB I;  2SGD I;  2GKT I;  1HDL A;  1SGY I;  2N71 A;  1LR9 A;  1SGP I;  4GI3 C;  1TGS I;  2SGP I;  2NU3 I;  1OYV I;  1TBQ R;  1Y1C A;  1TBR R;  1BUS A;  1CGJ I;  1IY5 A;  1OVO A;  2N52 A;  1H0Z A;  2ARP F;  3OVO A;  3SGQ I;  1SGR I;  2N17 A;  1HPT A;  5DAE A;  1CT2 I; 
#chains in the Genus database with same CATH topology
 1M8B A;  2FNF X;  1W4R A;  3TO9 A;  2K9H A;  2M5X A;  3TO6 A;  3R5D A;  1FYB A;  2V1C A;  2OU2 A;  2X52 A;  1MT1 A;  5HQ8 A;  4B6D A;  1K7V A;  3UGI A;  7WGA A;  1SGE I;  1XA6 A;  5J8F A;  1MJA A;  2ORW A;  1CGI I;  2ORV A;  1MJB A;  1ULN A;  3HH2 C;  2V53 A;  1CT4 I;  2ENN A;  3TOA A;  5HI7 A;  4E1P A;  1CT0 I;  5EX0 A;  2WCY A;  3E2I A;  5FUY A;  2B0U C;  1IY6 A;  1P9Z A;  2B8T A;  2DIP A;  2Y0M A;  1M8C A;  1DS3 I;  1TIH A;  1V1H A;  1WKX A;  2CWG A;  3R5A A;  5FUX A;  3UEY A;  1Q9B A;  1Y1B A;  2P6A C;  3SGB I;  1V1I A;  1S20 A;  2KMR A;  2SGE I;  2WVJ A;  2E73 A;  1CE3 A;  1ULK A;  2KCX A;  3QWP A;  3QTL D;  1IW4 A;  1OMU A;  2JXD A;  3E59 A;  4HGU A;  1CHO I;  1LR7 A;  1PPF I;  2UVO A;  4UXJ A;  2KMQ A;  2NU2 I;  2UZ3 A;  1NUB A;  1TBN A;  1AN1 I;  1KMA A;  1KBF A;  3R5C A;  4A24 A;  1N13 A;  1LR8 A;  1MJ9 A;  1PJU A;  3UFF A;  3R5B A;  1VDD A;  1Y8F A;  1R0R I;  2JYY A;  2ERW A;  2DB6 A;  1ULM A;  1Z7K B;  2CJS C;  2RIJ A;  4UXH A;  1SGD I;  1SGN I;  3OXL A;  3PDN A;  5E3R A;  1XX6 A;  3BJI A;  3TJQ A;  1CSO I;  1PTQ A;  2CWH A;  2QQE A;  1TUR A;  1YTP A;  2PQ8 A;  5FUW A;  1PCE A;  1BMO A;  1PTR A;  2W0T A;  3UGD A;  1K7T A;  3GOX A;  1Z2I A;  2QQ0 A;  4L9M A;  1X4S A;  1RFH A;  2YQP A;  2F3C I;  2QQD A;  1HEV A;  2GKR I;  3SEK C;  1WGT A;  1DS2 I;  2DKV A;  2X3T A;  1HJA I;  2NU0 I;  3FSY A;  2GKV A;  2JW6 A;  2BUS A;  4E1R A;  3MEK A;  1UVG A;  1P9G A;  1W3S A;  2J9R A;  1WTJ A;  2KMP A;  3B4V C;  1SGQ I;  1TOT A;  1FY7 A;  2A20 A;  2JZM A;  3KY9 A;  1UVF A;  4MPI A;  4OVO A;  2OD1 A;  2KMO A;  2N1A B;  2SGF I;  4UXI A;  4DNC A;  1YU6 C;  1U5K A;  1OMT A;  1UUC A;  2LUY A;  1TUS A;  5JHW C;  2XRC A;  4JCV E;  3UEJ A;  1X74 A;  2LB7 A;  2OVO A;  3UOE A;  3D00 A;  2ODD A;  2NU1 I;  2CWF A;  2NU4 I;  3UGL A;  1K7U A;  2QQC A;  2OZU A;  2ROW A;  2V1C C;  3RU0 A;  3FC3 A;  3QAH A;  2LEO A;  2SGQ I;  2ELI A;  3OL0 A;  4SGB I;  2VRW B;  1KBE A;  2SGD I;  1R79 A;  2GKT I;  4FKD A;  5CCL A;  1FAQ A;  2YUU A;  1HDL A;  1SGY I;  2J87 A;  2GIV A;  3OXF A;  3OXG A;  1WGC A;  2L7X A;  9WGA A;  2N71 A;  1LR9 A;  1SGP I;  4GI3 C;  1TGS I;  2SGP I;  2JA1 A;  2NU3 I;  1OYV I;  3CXL A;  5E3P A;  1FAR A;  1TBQ R;  1Y1C A;  5J8C A;  1TBR R;  1XBT A;  2ENZ A;  2GVI A;  3VE5 A;  2WGC A;  1BUS A;  1UHA A;  2RC4 A;  5CCM A;  3TOB A;  2L8E A;  1CGJ I;  1IY5 A;  1OVO A;  1TBO A;  2N52 A;  3TO7 A;  1H0Z A;  4WP4 A;  3VDU A;  2ARP F;  3OVO A;  3SGQ I;  1SGR I;  3FSX A;  5EX3 A;  3VDP A;  4AML A;  2N17 A;  1NXU A;  2QPO A;  1HPT A;  2E5R A;  5DAE A;  1CT2 I;  5FUV A;  5E3Q A; 
#chains in the Genus database with same CATH homology
 1M8B A;  2FNF X;  1W4R A;  2K9H A;  2M5X A;  1FYB A;  2V1C A;  1MT1 A;  5HQ8 A;  4B6D A;  3UGI A;  1SGE I;  1XA6 A;  2ORW A;  1CGI I;  2ORV A;  3HH2 C;  2V53 A;  1CT4 I;  2ENN A;  4E1P A;  5HI7 A;  1CT0 I;  5EX0 A;  2WCY A;  3E2I A;  5FUY A;  2B0U C;  1IY6 A;  2B8T A;  2DIP A;  1M8C A;  1DS3 I;  1TIH A;  1V1H A;  5FUX A;  3UEY A;  1Y1B A;  2P6A C;  3SGB I;  1V1I A;  2KMR A;  2SGE I;  2WVJ A;  2E73 A;  1CE3 A;  2KCX A;  3QWP A;  3QTL D;  1IW4 A;  1OMU A;  2JXD A;  3E59 A;  4HGU A;  1CHO I;  1LR7 A;  1PPF I;  4UXJ A;  2KMQ A;  2NU2 I;  2UZ3 A;  1NUB A;  1TBN A;  1AN1 I;  1KMA A;  1KBF A;  4A24 A;  1N13 A;  1LR8 A;  1PJU A;  3UFF A;  1VDD A;  1Y8F A;  1R0R I;  2JYY A;  2ERW A;  2DB6 A;  4UXH A;  1Z7K B;  2CJS C;  1SGD I;  1SGN I;  3OXL A;  3PDN A;  1XX6 A;  3BJI A;  3TJQ A;  1CSO I;  1PTQ A;  2QQE A;  1TUR A;  1YTP A;  5FUW A;  1PCE A;  1BMO A;  1PTR A;  2W0T A;  3UGD A;  3GOX A;  2QQ0 A;  4L9M A;  1X4S A;  1RFH A;  2YQP A;  2F3C I;  2QQD A;  2GKR I;  3SEK C;  1DS2 I;  1HJA I;  2NU0 I;  2GKV A;  2JW6 A;  2BUS A;  4E1R A;  3MEK A;  1UVG A;  2J9R A;  1W3S A;  2KMP A;  3B4V C;  1SGQ I;  1TOT A;  2A20 A;  2JZM A;  3KY9 A;  1UVF A;  4OVO A;  2OD1 A;  2KMO A;  2N1A B;  2SGF I;  4UXI A;  1YU6 C;  1U5K A;  1OMT A;  1UUC A;  2LUY A;  1TUS A;  5JHW C;  2XRC A;  4JCV E;  3UEJ A;  1X74 A;  2OVO A;  3D00 A;  2ODD A;  2NU1 I;  2NU4 I;  3UGL A;  2ROW A;  2QQC A;  2V1C C;  3RU0 A;  3FC3 A;  2LEO A;  2SGQ I;  2ELI A;  3OL0 A;  4SGB I;  2VRW B;  1KBE A;  2SGD I;  1R79 A;  2GKT I;  4FKD A;  5CCL A;  1FAQ A;  2YUU A;  1HDL A;  1SGY I;  2J87 A;  3OXG A;  3OXF A;  2L7X A;  2N71 A;  1LR9 A;  1SGP I;  4GI3 C;  1TGS I;  2SGP I;  2JA1 A;  2NU3 I;  1OYV I;  3CXL A;  1FAR A;  1TBQ R;  1Y1C A;  1TBR R;  1XBT A;  2ENZ A;  2GVI A;  3VE5 A;  1BUS A;  5CCM A;  2L8E A;  1CGJ I;  1IY5 A;  1OVO A;  1TBO A;  2N52 A;  1H0Z A;  3VDU A;  2ARP F;  3OVO A;  3SGQ I;  1SGR I;  3VDP A;  5EX3 A;  2N17 A;  2QPO A;  1HPT A;  2E5R A;  5DAE A;  1CT2 I;  5FUV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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