1SJ7A

Crystal structure of talin rod 482-655
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
167
structure length
167
Chain Sequence
LTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Talin 1
total genus 70
structure length 167
sequence length 167
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2004-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09141 Talin_middle Talin, middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 1sj7A00
4W8PA 3DYJA 2X0CA 3AY5A 5FZTA 1SJ8A 2L10A 1SJ7A 2KBBA 2L7NA 4F7GB 2KGXA 3FYQA 2KVPA
chains in the Genus database with same CATH superfamily
5HXEA 3DYJA 5JDHA 1SJ8A 3PF0A 5JDMA 3WSCA 3M1CA 2KVPA 3AT7A 5FZTA 5HWXA 2LQUA 3V5UA 2L10A 2KBBA 5T1DA 5HYAA 5JDNA 4F7GB 3V5SA 4W8PA 5HXRA 2X0CA 3AY5A 3WURA 5HXHA 1SJ7A 5HXSA 3PHF1 4ONRA 2L7NA 2XQYA 5HXCA 5HWYA 3VJZA 5JDLA 4ECGA 5JDQA 2MTCA 5JDFA 2KGXA 4BGOA 5JDGA 3FYQA
chains in the Genus database with same CATH topology
4W8PA 3DYJA 2X0CA 3AY5A 5FZTA 1SJ8A 2L10A 1SJ7A 2KBBA 2L7NA 4F7GB 2KGXA 3FYQA 2KVPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4W8P A;  3DYJ A;  2X0C A;  3AY5 A;  5FZT A;  1SJ8 A;  2L10 A;  1SJ7 A;  2KBB A;  2L7N A;  4F7G B;  2KGX A;  3FYQ A;  2KVP A; 
#chains in the Genus database with same CATH topology
 5HXE A;  3DYJ A;  5JDH A;  1SJ8 A;  3PF0 A;  5JDM A;  3WSC A;  3M1C A;  2KVP A;  3AT7 A;  5FZT A;  5HWX A;  2LQU A;  3V5U A;  2L10 A;  2KBB A;  5T1D A;  5HYA A;  5JDN A;  4F7G B;  3V5S A;  4W8P A;  5HXR A;  2X0C A;  3AY5 A;  3WUR A;  5HXH A;  1SJ7 A;  5HXS A;  3PHF 1;  4ONR A;  2L7N A;  2XQY A;  5HXC A;  5HWY A;  3VJZ A;  5JDL A;  4ECG A;  5JDQ A;  2MTC A;  5JDF A;  2KGX A;  4BGO A;  5JDG A;  3FYQ A; 
#chains in the Genus database with same CATH homology
 4W8P A;  3DYJ A;  2X0C A;  3AY5 A;  5FZT A;  1SJ8 A;  2L10 A;  1SJ7 A;  2KBB A;  2L7N A;  4F7G B;  2KGX A;  3FYQ A;  2KVP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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