1SJ8A

Crystal structure of talin residues 482-789
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
297
structure length
297
Chain Sequence
b'PPLTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQIGESDTDPHFQDVLMQLANAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Talin 1
publication title Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
pubmed doi rcsb
source organism Mus musculus
molecule tags Structural protein
total genus 119
structure length 297
sequence length 297
ec nomenclature
pdb deposition date 2004-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09141 Talin_middle Talin, middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 1sj8A01
1.20.1440.10 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 1sj8A02
3DYJA 2L7NA 1YO7A 3FYQA 2L10A 4W8PA 5FZTA 1SJ8A 3AY5A 1SJ7A 2X0CA 2KBBA 4F7GB 2KVPA 2KGXA
chains in the Genus database with same CATH superfamily
2V1CC 2FU2A 2BL7A 2P22B 2QSBA 1YO7A 2L10A 2FEFA 2LQUA 3LJ1A 2MTCA 2F6MB 2CAZB 2YFBA 4U6RA 4OAUC 4ECGA 3FBVA 3FYQA 5HXRA 2JBWA 2IP6A 5HXSA 3VJZA 4YZCA 2KBBA 3JSBA 5JDFA 2XMXA 2ZW3A 2JB2A 3AY5A 3WURA 4PL5A 3WSCA 4I1TA 2BL8A 4F7GB 4Z7GA 3Q8DA 2JB1A 2K19A 2HGKA 2QZGA 4BGOA 5HXCA 5HYAA 4G76A 5JDMA 2RADA 4GXTA 5FZTA 3AJFA 3IAM1 4AS3A 2KKMA 3PF0A 3P23A 2F66B 3DYJA 2YFAA 5JDLA 2JB3A 3B55A 4DWLA 3LJ0A 4Q9VA 5JDHA 2E8GA 4W8PA 2RLDA 3L0IA 3I9V1 2X0CA 2L1LB 5HGIA 4AS2A 2GSCA 4YZDA 5HWYA 1TDPA 5JDNA 2RIOA 5HWXA 3DO9A 2V6EA 2KGXA 2FUG1 4PL4A 5JDGA 5JDQA 2MJFB 4O1PA 4YZ9A 2ETDA 5LNK1 4G75A 4NV2A 1W3SA 4HEA1 3UITA 2L7NA 3V5SA 2ZRRA 1SJ7A 3AT7A 4NV5A 3KP9A 4OAVB 5HXHA 4PL3A 3DA3A 3F4MA 4JCVE 5HXEA 5T1DA 3LJ2A 1SJ8A 2A2DA 4Z7HA 3FVVA 4HFVA 3DA4A 4ONRA 3IAS1 2JAEA 3FNBA 2KVPA 2XTRA 2XTQA 3VA9A 2A2CA 3M1CA 4O1OA 2XQYA 3V5UA 3SDJA 2QGMA 1JQOA 3PHF1 1U5KA
chains in the Genus database with same CATH topology
2V1CC 2P22B 1YO7A 2L10A 3LJ1A 2F6MB 2CAZB 2YFBA 4U6RA 4OAUC 3FBVA 3FYQA 2IP6A 4YZCA 2KBBA 3JSBA 2XMXA 2JB2A 3AY5A 4PL5A 4I1TA 4F7GB 4Z7GA 3Q8DA 2JB1A 2K19A 4G76A 4GXTA 5FZTA 3AJFA 3IAM1 4AS3A 2KKMA 3P23A 2F66B 3DYJA 2YFAA 2JB3A 4DWLA 3LJ0A 4Q9VA 2E8GA 4W8PA 3L0IA 3I9V1 2X0CA 2L1LB 5HGIA 4AS2A 4YZDA 2RIOA 3DO9A 2V6EA 2KGXA 2FUG1 4PL4A 2MJFB 4O1PA 4YZ9A 5LNK1 4G75A 4NV2A 1W3SA 4HEA1 3UITA 2L7NA 2ZRRA 1SJ7A 4NV5A 3KP9A 4OAVB 4PL3A 3DA3A 3F4MA 4JCVE 3LJ2A 1SJ8A 2A2DA 4Z7HA 4HFVA 3DA4A 3IAS1 2JAEA 2KVPA 2XTRA 2XTQA 3VA9A 2A2CA 4O1OA 3SDJA 1U5KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYJ A;  2L7N A;  1YO7 A;  3FYQ A;  2L10 A;  4W8P A;  5FZT A;  1SJ8 A;  3AY5 A;  1SJ7 A;  2X0C A;  2KBB A;  4F7G B;  2KVP A;  2KGX A; 
#chains in the Genus database with same CATH topology
 2V1C C;  2FU2 A;  2BL7 A;  2P22 B;  2QSB A;  1YO7 A;  2L10 A;  2FEF A;  2LQU A;  3LJ1 A;  2MTC A;  2F6M B;  2CAZ B;  2YFB A;  4U6R A;  4OAU C;  4ECG A;  3FBV A;  3FYQ A;  5HXR A;  2JBW A;  2IP6 A;  5HXS A;  3VJZ A;  4YZC A;  2KBB A;  3JSB A;  5JDF A;  2XMX A;  2ZW3 A;  2JB2 A;  3AY5 A;  3WUR A;  4PL5 A;  3WSC A;  4I1T A;  2BL8 A;  4F7G B;  4Z7G A;  3Q8D A;  2JB1 A;  2K19 A;  2HGK A;  2QZG A;  4BGO A;  5HXC A;  5HYA A;  4G76 A;  5JDM A;  2RAD A;  4GXT A;  5FZT A;  3AJF A;  3IAM 1;  4AS3 A;  2KKM A;  3PF0 A;  3P23 A;  2F66 B;  3DYJ A;  2YFA A;  5JDL A;  2JB3 A;  3B55 A;  4DWL A;  3LJ0 A;  4Q9V A;  5JDH A;  2E8G A;  4W8P A;  2RLD A;  3L0I A;  3I9V 1;  2X0C A;  2L1L B;  5HGI A;  4AS2 A;  2GSC A;  4YZD A;  5HWY A;  1TDP A;  5JDN A;  2RIO A;  5HWX A;  3DO9 A;  2V6E A;  2KGX A;  2FUG 1;  4PL4 A;  5JDG A;  5JDQ A;  2MJF B;  4O1P A;  4YZ9 A;  2ETD A;  5LNK 1;  4G75 A;  4NV2 A;  1W3S A;  4HEA 1;  3UIT A;  2L7N A;  3V5S A;  2ZRR A;  1SJ7 A;  3AT7 A;  4NV5 A;  3KP9 A;  4OAV B;  5HXH A;  4PL3 A;  3DA3 A;  3F4M A;  4JCV E;  5HXE A;  5T1D A;  3LJ2 A;  1SJ8 A;  2A2D A;  4Z7H A;  3FVV A;  4HFV A;  3DA4 A;  4ONR A;  3IAS 1;  2JAE A;  3FNB A;  2KVP A;  2XTR A;  2XTQ A;  3VA9 A;  2A2C A;  3M1C A;  4O1O A;  2XQY A;  3V5U A;  3SDJ A;  2QGM A;  1JQO A;  3PHF 1;  1U5K A; 
#chains in the Genus database with same CATH homology
 2V1C C;  2P22 B;  1YO7 A;  2L10 A;  3LJ1 A;  2F6M B;  2CAZ B;  2YFB A;  4U6R A;  4OAU C;  3FBV A;  3FYQ A;  2IP6 A;  4YZC A;  2KBB A;  3JSB A;  2XMX A;  2JB2 A;  3AY5 A;  4PL5 A;  4I1T A;  4F7G B;  4Z7G A;  3Q8D A;  2JB1 A;  2K19 A;  4G76 A;  4GXT A;  5FZT A;  3AJF A;  3IAM 1;  4AS3 A;  2KKM A;  3P23 A;  2F66 B;  3DYJ A;  2YFA A;  2JB3 A;  4DWL A;  3LJ0 A;  4Q9V A;  2E8G A;  4W8P A;  3L0I A;  3I9V 1;  2X0C A;  2L1L B;  5HGI A;  4AS2 A;  4YZD A;  2RIO A;  3DO9 A;  2V6E A;  2KGX A;  2FUG 1;  4PL4 A;  2MJF B;  4O1P A;  4YZ9 A;  5LNK 1;  4G75 A;  4NV2 A;  1W3S A;  4HEA 1;  3UIT A;  2L7N A;  2ZRR A;  1SJ7 A;  4NV5 A;  3KP9 A;  4OAV B;  4PL3 A;  3DA3 A;  3F4M A;  4JCV E;  3LJ2 A;  1SJ8 A;  2A2D A;  4Z7H A;  4HFV A;  3DA4 A;  3IAS 1;  2JAE A;  2KVP A;  2XTR A;  2XTQ A;  3VA9 A;  2A2C A;  4O1O A;  3SDJ A;  1U5K A; 
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