The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
67
|
sequence length |
248
|
structure length |
208
|
Chain Sequence |
b'RSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTDPAEYAHLVQAIIENPFLNGEVIRL'
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
pubmed doi rcsb |
| molecule keywords |
3-hydroxyacyl-CoA dehydrogenase type II
|
| source organism |
Homo sapiens
|
| molecule tags |
Oxidoreductase
|
| total genus |
67
|
| structure length |
208
|
| sequence length |
248
|
| ec nomenclature |
ec
1.1.1.178: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase. |
| pdb deposition date | 2004-03-13 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00106 | adh_short | short chain dehydrogenase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain |
