1SR4B

Crystal structure of the haemophilus ducreyi cytolethal distending toxin
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
261
structure length
258
Chain Sequence
NLSDFKVATWNLQGSSAVNESKWNINVRQLLSGEQGADILMVQEAGSLPSSAVRTSRVIQHGGTPIEEYTWNLGTRSRPNMVYIYYSRLDVGANRVNLAIVSRRQADEAFIVHSDSSVLQSRPAVGIRIGTDVFFTVHALATGGSDAVSLIRNIFTTFNSPPERRVYSWMVVGDFNRAPANLEVALRQEPAVSENTIIIAPTEPTHRSGNILDYAILHDAHLPRREQARERIGASLMLNQLRSQITSDHFPVSFVRDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Assembly and Function of a Bacterial Genotoxin
pubmed doi rcsb
molecule tags Toxin
source organism Haemophilus ducreyi
molecule keywords Cytolethal distending toxin subunit A
total genus 80
structure length 258
sequence length 261
ec nomenclature
pdb deposition date 2004-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 1sr4B00
4GZ0A 1DNKA 3G2CA 2IMQX 3G1KA 3FZIA 1I9ZA 4F1IA 5INOA 5DFHA 3W2YA 2DNJA 1ZWXA 4PUQA 1BIXA 5INQA 4CMLA 2A40B 2DDTA 5J8NA 4B5HA 5DG0A 4QHEA 5J3PA 2F2FB 3G6SA 3NGQA 3I46A 4RUWA 1I9YA 3G91A 1DEWA 5DV2A 1AKOA 3L1WA 3I5VA 2F1NA 2A3ZB 3MTCA 4B5IA 5EWTA 4F1HB 3W3DB 2JC5A 5HT2A 1YJHA 3NGOA 2EI9A 5INMA 3G4TA 2XSWA 5A7IA 2O3CA 4JG3A 4IEMA 3G38A 4B5FA 4F1RA 4L1ZA 4F1HA 4LNDA 3TEBA 5CFEA 1SI6X 2A42B 2O3HA 2V0SA 2VOAA 1WDUA 5INKA 2DDRA 1DE8A 3MPRA 2JC4A 1ATND 3W2XA 3G3CA 3WCXA 4C1RA 4CMNA 3G0AA 4B5MA 1Y21A 3I41A 4FVAA 3G8VA 4FPVA 5J3ZA 5J3SA 5DV4A 4L1YA 3G0RA 4GYZA 4L20A 2A41B 4AWNA 5CFGA 3NR8A 3G3YA 1NTFA 3G00A 4GEWA 4B5JA 4GZ2A 3N9VA 3DNIA 4L21A 3K55A 5J42A 3G2DA 4B5GA 4K6LF 2V0RA 3GA6A 1VYBA 1DE9A 1HD7A 2ISIA 3NGNA 5INLA 3I48A 2J63A 4GZ1A 4A9CA 5INPA 3CJCD 2D1KB 5A7JA 5INNA 5DFIA 5DFJA 1SR4B 2DDSA 2UYRX 4QHDA 1E9NA 4QH9A 3U8UA 5DFFA
chains in the Genus database with same CATH superfamily
4GZ0A 1DNKA 3G2CA 2IMQX 3G1KA 3FZIA 1I9ZA 4F1IA 5INOA 5DFHA 3W2YA 2DNJA 1ZWXA 4PUQA 1BIXA 5INQA 4CMLA 2A40B 2DDTA 5J8NA 4B5HA 5DG0A 4QHEA 5J3PA 2F2FB 3G6SA 3NGQA 3I46A 4RUWA 1I9YA 3G91A 1DEWA 5DV2A 1AKOA 3L1WA 3I5VA 2F1NA 2A3ZB 3MTCA 4B5IA 5EWTA 4F1HB 3W3DB 2JC5A 5HT2A 1YJHA 3NGOA 2EI9A 5INMA 3G4TA 2XSWA 5A7IA 2O3CA 4JG3A 4IEMA 3G38A 4B5FA 4F1RA 4L1ZA 4F1HA 4LNDA 3TEBA 5CFEA 1SI6X 2A42B 2O3HA 2V0SA 2VOAA 1WDUA 5INKA 2DDRA 1DE8A 3MPRA 2JC4A 1ATND 3W2XA 3G3CA 3WCXA 4C1RA 4CMNA 3G0AA 4B5MA 1Y21A 3I41A 4FVAA 3G8VA 4FPVA 5J3ZA 5J3SA 5DV4A 4L1YA 3G0RA 4GYZA 4L20A 2A41B 4AWNA 5CFGA 3NR8A 3G3YA 1NTFA 3G00A 4GEWA 4B5JA 4GZ2A 3N9VA 3DNIA 4L21A 3K55A 5J42A 3G2DA 4B5GA 4K6LF 2V0RA 3GA6A 1VYBA 1DE9A 1HD7A 2ISIA 3NGNA 5INLA 3I48A 2J63A 4GZ1A 4A9CA 5INPA 3CJCD 2D1KB 5A7JA 5INNA 5DFIA 5DFJA 1SR4B 2DDSA 2UYRX 4QHDA 1E9NA 4QH9A 3U8UA 5DFFA
chains in the Genus database with same CATH topology
4GZ0A 1DNKA 3G2CA 2IMQX 3G1KA 3FZIA 1I9ZA 4F1IA 5INOA 5DFHA 3W2YA 2DNJA 1ZWXA 4PUQA 1BIXA 5INQA 4CMLA 2A40B 2DDTA 5J8NA 4B5HA 5DG0A 4QHEA 5J3PA 2F2FB 3G6SA 3NGQA 3I46A 4RUWA 1I9YA 3G91A 1DEWA 5DV2A 1AKOA 3L1WA 3I5VA 2F1NA 2A3ZB 3MTCA 4B5IA 5EWTA 4F1HB 3W3DB 2JC5A 5HT2A 1YJHA 3NGOA 2EI9A 5INMA 3G4TA 2XSWA 5A7IA 2O3CA 4JG3A 4IEMA 3G38A 4B5FA 4F1RA 4L1ZA 4F1HA 4LNDA 3TEBA 5CFEA 1SI6X 2A42B 2O3HA 2V0SA 2VOAA 1WDUA 5INKA 2DDRA 1DE8A 3MPRA 2JC4A 1ATND 3W2XA 3G3CA 3WCXA 4C1RA 4CMNA 3G0AA 4B5MA 1Y21A 3I41A 4FVAA 3G8VA 4FPVA 5J3ZA 5J3SA 5DV4A 4L1YA 3G0RA 4GYZA 4L20A 2A41B 4AWNA 5CFGA 3NR8A 3G3YA 1NTFA 3G00A 4GEWA 4B5JA 4GZ2A 3N9VA 3DNIA 4L21A 3K55A 5J42A 3G2DA 4B5GA 4K6LF 2V0RA 3GA6A 1VYBA 1DE9A 1HD7A 2ISIA 3NGNA 5INLA 3I48A 2J63A 4GZ1A 4A9CA 5INPA 3CJCD 2D1KB 5A7JA 5INNA 5DFIA 5DFJA 1SR4B 2DDSA 2UYRX 4QHDA 1E9NA 4QH9A 3U8UA 5DFFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GZ0 A;  1DNK A;  3G2C A;  2IMQ X;  3G1K A;  3FZI A;  1I9Z A;  4F1I A;  5INO A;  5DFH A;  3W2Y A;  2DNJ A;  1ZWX A;  4PUQ A;  1BIX A;  5INQ A;  4CML A;  2A40 B;  2DDT A;  5J8N A;  4B5H A;  5DG0 A;  4QHE A;  5J3P A;  2F2F B;  3G6S A;  3NGQ A;  3I46 A;  4RUW A;  1I9Y A;  3G91 A;  1DEW A;  5DV2 A;  1AKO A;  3L1W A;  3I5V A;  2F1N A;  2A3Z B;  3MTC A;  4B5I A;  5EWT A;  4F1H B;  3W3D B;  2JC5 A;  5HT2 A;  1YJH A;  3NGO A;  2EI9 A;  5INM A;  3G4T A;  2XSW A;  5A7I A;  2O3C A;  4JG3 A;  4IEM A;  3G38 A;  4B5F A;  4F1R A;  4L1Z A;  4F1H A;  4LND A;  3TEB A;  5CFE A;  1SI6 X;  2A42 B;  2O3H A;  2V0S A;  2VOA A;  1WDU A;  5INK A;  2DDR A;  1DE8 A;  3MPR A;  2JC4 A;  1ATN D;  3W2X A;  3G3C A;  3WCX A;  4C1R A;  4CMN A;  3G0A A;  4B5M A;  1Y21 A;  3I41 A;  4FVA A;  3G8V A;  4FPV A;  5J3Z A;  5J3S A;  5DV4 A;  4L1Y A;  3G0R A;  4GYZ A;  4L20 A;  2A41 B;  4AWN A;  5CFG A;  3NR8 A;  3G3Y A;  1NTF A;  3G00 A;  4GEW A;  4B5J A;  4GZ2 A;  3N9V A;  3DNI A;  4L21 A;  3K55 A;  5J42 A;  3G2D A;  4B5G A;  4K6L F;  2V0R A;  3GA6 A;  1VYB A;  1DE9 A;  1HD7 A;  2ISI A;  3NGN A;  5INL A;  3I48 A;  2J63 A;  4GZ1 A;  4A9C A;  5INP A;  3CJC D;  2D1K B;  5A7J A;  5INN A;  5DFI A;  5DFJ A;  1SR4 B;  2DDS A;  2UYR X;  4QHD A;  1E9N A;  4QH9 A;  3U8U A;  5DFF A; 
#chains in the Genus database with same CATH topology
 4GZ0 A;  1DNK A;  3G2C A;  2IMQ X;  3G1K A;  3FZI A;  1I9Z A;  4F1I A;  5INO A;  5DFH A;  3W2Y A;  2DNJ A;  1ZWX A;  4PUQ A;  1BIX A;  5INQ A;  4CML A;  2A40 B;  2DDT A;  5J8N A;  4B5H A;  5DG0 A;  4QHE A;  5J3P A;  2F2F B;  3G6S A;  3NGQ A;  3I46 A;  4RUW A;  1I9Y A;  3G91 A;  1DEW A;  5DV2 A;  1AKO A;  3L1W A;  3I5V A;  2F1N A;  2A3Z B;  3MTC A;  4B5I A;  5EWT A;  4F1H B;  3W3D B;  2JC5 A;  5HT2 A;  1YJH A;  3NGO A;  2EI9 A;  5INM A;  3G4T A;  2XSW A;  5A7I A;  2O3C A;  4JG3 A;  4IEM A;  3G38 A;  4B5F A;  4F1R A;  4L1Z A;  4F1H A;  4LND A;  3TEB A;  5CFE A;  1SI6 X;  2A42 B;  2O3H A;  2V0S A;  2VOA A;  1WDU A;  5INK A;  2DDR A;  1DE8 A;  3MPR A;  2JC4 A;  1ATN D;  3W2X A;  3G3C A;  3WCX A;  4C1R A;  4CMN A;  3G0A A;  4B5M A;  1Y21 A;  3I41 A;  4FVA A;  3G8V A;  4FPV A;  5J3Z A;  5J3S A;  5DV4 A;  4L1Y A;  3G0R A;  4GYZ A;  4L20 A;  2A41 B;  4AWN A;  5CFG A;  3NR8 A;  3G3Y A;  1NTF A;  3G00 A;  4GEW A;  4B5J A;  4GZ2 A;  3N9V A;  3DNI A;  4L21 A;  3K55 A;  5J42 A;  3G2D A;  4B5G A;  4K6L F;  2V0R A;  3GA6 A;  1VYB A;  1DE9 A;  1HD7 A;  2ISI A;  3NGN A;  5INL A;  3I48 A;  2J63 A;  4GZ1 A;  4A9C A;  5INP A;  3CJC D;  2D1K B;  5A7J A;  5INN A;  5DFI A;  5DFJ A;  1SR4 B;  2DDS A;  2UYR X;  4QHD A;  1E9N A;  4QH9 A;  3U8U A;  5DFF A; 
#chains in the Genus database with same CATH homology
 4GZ0 A;  1DNK A;  3G2C A;  2IMQ X;  3G1K A;  3FZI A;  1I9Z A;  4F1I A;  5INO A;  5DFH A;  3W2Y A;  2DNJ A;  1ZWX A;  4PUQ A;  1BIX A;  5INQ A;  4CML A;  2A40 B;  2DDT A;  5J8N A;  4B5H A;  5DG0 A;  4QHE A;  5J3P A;  2F2F B;  3G6S A;  3NGQ A;  3I46 A;  4RUW A;  1I9Y A;  3G91 A;  1DEW A;  5DV2 A;  1AKO A;  3L1W A;  3I5V A;  2F1N A;  2A3Z B;  3MTC A;  4B5I A;  5EWT A;  4F1H B;  3W3D B;  2JC5 A;  5HT2 A;  1YJH A;  3NGO A;  2EI9 A;  5INM A;  3G4T A;  2XSW A;  5A7I A;  2O3C A;  4JG3 A;  4IEM A;  3G38 A;  4B5F A;  4F1R A;  4L1Z A;  4F1H A;  4LND A;  3TEB A;  5CFE A;  1SI6 X;  2A42 B;  2O3H A;  2V0S A;  2VOA A;  1WDU A;  5INK A;  2DDR A;  1DE8 A;  3MPR A;  2JC4 A;  1ATN D;  3W2X A;  3G3C A;  3WCX A;  4C1R A;  4CMN A;  3G0A A;  4B5M A;  1Y21 A;  3I41 A;  4FVA A;  3G8V A;  4FPV A;  5J3Z A;  5J3S A;  5DV4 A;  4L1Y A;  3G0R A;  4GYZ A;  4L20 A;  2A41 B;  4AWN A;  5CFG A;  3NR8 A;  3G3Y A;  1NTF A;  3G00 A;  4GEW A;  4B5J A;  4GZ2 A;  3N9V A;  3DNI A;  4L21 A;  3K55 A;  5J42 A;  3G2D A;  4B5G A;  4K6L F;  2V0R A;  3GA6 A;  1VYB A;  1DE9 A;  1HD7 A;  2ISI A;  3NGN A;  5INL A;  3I48 A;  2J63 A;  4GZ1 A;  4A9C A;  5INP A;  3CJC D;  2D1K B;  5A7J A;  5INN A;  5DFI A;  5DFJ A;  1SR4 B;  2DDS A;  2UYR X;  4QHD A;  1E9N A;  4QH9 A;  3U8U A;  5DFF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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