1SSLA

Solution structure of the psi domain from the met receptor
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
48
structure length
48
Chain Sequence
GSAMGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into function of PSI domains from structure of the Met receptor PSI domain.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Hepatocyte growth factor receptor
total genus 4
structure length 48
sequence length 48
ec nomenclature ec 2.7.10.1: Receptor protein-tyrosine kinase.
pdb deposition date 2004-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01437 PSI Plexin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1680.10 Alpha Beta 2-Layer Sandwich ligand-binding face of the semaphorins, domain 2 ligand-binding face of the semaphorins, domain 2 1sslA00
4WK2B 4Z7OB 4O3TB 3ZE2B 2P28A 3NIGB 4Z7QB 4UM8B 3ZDYB 4WK4B 2VDMB 3T3MB 4O3UB 2VDRB 2VDPB 3OL2B 4GZ8A 4K3JB 1SSLA 2VDNB 1SHYB 3AL9A 4Z7NB 4WJKB 1YUKA 3NIFB 2VC2B 3FCUB 3ZE0B 1OLZA 3OKWA 3OL2A 1TYEB 3ZE1B 2VDLB 2P26A 5E6SB 3ZDXB 3AL8B 4FWWA 3VI4B 5E6UB 3ZDZB 2UZYB 3NIDB 3VI3B 3OKYB 4UM9D 2VDQB 3NVQA 4WK0B 1U8CB 3AL8A 2VDKB 3AFCA 5HDBB 2VDOB 5E6RB 3T3PB 4UM9B
chains in the Genus database with same CATH superfamily
4WK2B 4Z7OB 4O3TB 3ZE2B 2P28A 3NIGB 4Z7QB 4UM8B 3ZDYB 4WK4B 2VDMB 3T3MB 4O3UB 2VDPB 2VDRB 3OL2B 4GZ8A 4K3JB 1SSLA 2VDNB 1SHYB 3AL9A 4Z7NB 4WJKB 1YUKA 3NIFB 2VC2B 2JWGA 3FCUB 3ZE0B 1OLZA 3OKWA 3OL2A 1TYEB 3ZE1B 2VDLB 2P26A 5E6SB 3ZDXB 3AL8B 4FWWA 3VI4B 5E6UB 3ZDZB 2UZYB 3NIDB 3VI3B 3OKYB 4UM9D 2VDQB 3NVQA 4WK0B 1U8CB 3AL8A 2VDKB 3AFCA 5HDBB 2JWHA 2VDOB 5E6RB 3T3PB 4UM9B
chains in the Genus database with same CATH topology
4WK2B 4Z7OB 4O3TB 3ZE2B 2P28A 3NIGB 4Z7QB 4UM8B 3ZDYB 4WK4B 2VDMB 3T3MB 4O3UB 2VDPB 2VDRB 3OL2B 4GZ8A 4K3JB 1SSLA 2VDNB 1SHYB 3AL9A 4Z7NB 4WJKB 1YUKA 3NIFB 2VC2B 2JWGA 3FCUB 3ZE0B 1OLZA 3OKWA 3OL2A 1TYEB 3ZE1B 2VDLB 2P26A 5E6SB 3ZDXB 3AL8B 4FWWA 3VI4B 5E6UB 3ZDZB 2UZYB 3NIDB 3VI3B 3OKYB 4UM9D 2VDQB 3NVQA 4WK0B 1U8CB 3AL8A 2VDKB 3AFCA 5HDBB 2JWHA 2VDOB 5E6RB 3T3PB 4UM9B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WK2 B;  4Z7O B;  4O3T B;  3ZE2 B;  2P28 A;  3NIG B;  4Z7Q B;  4UM8 B;  3ZDY B;  4WK4 B;  2VDM B;  3T3M B;  4O3U B;  2VDR B;  2VDP B;  3OL2 B;  4GZ8 A;  4K3J B;  1SSL A;  2VDN B;  1SHY B;  3AL9 A;  4Z7N B;  4WJK B;  1YUK A;  3NIF B;  2VC2 B;  3FCU B;  3ZE0 B;  1OLZ A;  3OKW A;  3OL2 A;  1TYE B;  3ZE1 B;  2VDL B;  2P26 A;  5E6S B;  3ZDX B;  3AL8 B;  4FWW A;  3VI4 B;  5E6U B;  3ZDZ B;  2UZY B;  3NID B;  3VI3 B;  3OKY B;  4UM9 D;  2VDQ B;  3NVQ A;  4WK0 B;  1U8C B;  3AL8 A;  2VDK B;  3AFC A;  5HDB B;  2VDO B;  5E6R B;  3T3P B;  4UM9 B; 
#chains in the Genus database with same CATH topology
 4WK2 B;  4Z7O B;  4O3T B;  3ZE2 B;  2P28 A;  3NIG B;  4Z7Q B;  4UM8 B;  3ZDY B;  4WK4 B;  2VDM B;  3T3M B;  4O3U B;  2VDP B;  2VDR B;  3OL2 B;  4GZ8 A;  4K3J B;  1SSL A;  2VDN B;  1SHY B;  3AL9 A;  4Z7N B;  4WJK B;  1YUK A;  3NIF B;  2VC2 B;  2JWG A;  3FCU B;  3ZE0 B;  1OLZ A;  3OKW A;  3OL2 A;  1TYE B;  3ZE1 B;  2VDL B;  2P26 A;  5E6S B;  3ZDX B;  3AL8 B;  4FWW A;  3VI4 B;  5E6U B;  3ZDZ B;  2UZY B;  3NID B;  3VI3 B;  3OKY B;  4UM9 D;  2VDQ B;  3NVQ A;  4WK0 B;  1U8C B;  3AL8 A;  2VDK B;  3AFC A;  5HDB B;  2JWH A;  2VDO B;  5E6R B;  3T3P B;  4UM9 B; 
#chains in the Genus database with same CATH homology
 4WK2 B;  4Z7O B;  4O3T B;  3ZE2 B;  2P28 A;  3NIG B;  4Z7Q B;  4UM8 B;  3ZDY B;  4WK4 B;  2VDM B;  3T3M B;  4O3U B;  2VDP B;  2VDR B;  3OL2 B;  4GZ8 A;  4K3J B;  1SSL A;  2VDN B;  1SHY B;  3AL9 A;  4Z7N B;  4WJK B;  1YUK A;  3NIF B;  2VC2 B;  2JWG A;  3FCU B;  3ZE0 B;  1OLZ A;  3OKW A;  3OL2 A;  1TYE B;  3ZE1 B;  2VDL B;  2P26 A;  5E6S B;  3ZDX B;  3AL8 B;  4FWW A;  3VI4 B;  5E6U B;  3ZDZ B;  2UZY B;  3NID B;  3VI3 B;  3OKY B;  4UM9 D;  2VDQ B;  3NVQ A;  4WK0 B;  1U8C B;  3AL8 A;  2VDK B;  3AFC A;  5HDB B;  2JWH A;  2VDO B;  5E6R B;  3T3P B;  4UM9 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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