1SVYA

Severin domain 2, 1.75 angstrom crystal structure
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
102
structure length
101
Chain Sequence
EYKPRLLHISGDKNAKVAEVPLATSSLNSGDCFLLDAGLTIYQFNGSKSSPQEKNKAAEVARAIDAERKGLPKVEVFETDSDIPAEFWKLLGGKGAIAAKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mapping the functional surface of domain 2 in the gelsolin superfamily.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Dictyostelium discoideum
molecule keywords SEVERIN
total genus 28
structure length 101
sequence length 102
ec nomenclature
pdb deposition date 1998-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1svyA00
2NUTB 5FAFA 2FF3A 3Q2BA 5KYWB 2FH2A 2W0IA 2LJ8A 1WFSA 1VFQA 1DEJS 5KYUA 5HVKB 1VKKA 4KEEA 4CBUG 1EQYS 3L50A 4CBWG 1QPVA 1T3YA 2NUPB 3A5OS 2L72A 2LXXA 3FG7A 3FG6A 4PKIG 1NM1G 3CJBG 5KYXA 3CJCG 1PD0A 4LIZA 2MP4A 1P8XA 1NLVG 1C0GS 2VACA 3FFNA 1HQZ1 2MOTA 3EG9B 3EGDA 3EGXB 1CFYA 3CI5G 5DD2A 1CNUA 2I2QA 1COFA 2QTVA 3A5LS 5HVKD 3A5MS 1AK7A 1SVYA 1ESVS 4S10C 1H1VG 5KYUB 2NUTA 1J72A 2VILA 2FGHA 2FH3A 1M2VB 5KYWA 1AHQA 5FAEA 5A1MA 1MDUA 1AK6A 1PD1A 1KCQA 1SVQA 2HD7A 4JD2H 5KYYB 2FF6G 3EFOB 1NPHA 4KEDA 3FFKA 2XF1A 3A5NS 2MV2A 1D4XG 2D8BA 4CBXG 1SVRA 1X67A 4KEFA 1PCXA 3EH1A 5IVUA 1NMDG 1M2OA 1YVNG 1RGIG 1C0FS 1WM4A 1TMWA 2FH1A 3EG9A 3EGXA 1V6FA 2VIKA 3CIPG 2LLFA 5L6WC 2KVKA 1UDMA 1P8ZG 1D0NA 1Q8GA 1TVJA 1WNJA 2FH4A 5KYXB 1M2VA 1Q8XA 2NUPA 1T3XA 1T44G 1JHWA 3EH2A 5KYNA 3TU5B 1YAGG 4Z94G 3EGDB 5KYYA 1M4JA 2XFAA 4BEX1 4PKGG 3EFOA 4PKHB 1F7SA 3DAWB 1T2LA
chains in the Genus database with same CATH superfamily
2NUTB 5FAFA 2FF3A 3DA7A 3Q2BA 5KYWB 2FH2A 2W0IA 2LJ8A 1WFSA 1VFQA 1DEJS 5KYUA 5HVKB 1VKKA 4KEEA 4CBUG 1EQYS 3L50A 4CBWG 1QPVA 1T3YA 2NUPB 3A5OS 2L72A 2LXXA 3FG7A 3FG6A 4PKIG 1NM1G 3CJBG 5KYXA 3CJCG 1PD0A 4LIZA 2MP4A 1P8XA 1NLVG 1C0GS 2VACA 3FFNA 1HQZ1 2MOTA 3EG9B 3EGDA 3EGXB 1CFYA 3CI5G 5DD2A 1CNUA 2I2QA 1COFA 2QTVA 3A5LS 5HVKD 3A5MS 1AK7A 1SVYA 1ESVS 4S10C 1H1VG 5KYUB 2NUTA 1J72A 2VILA 2FGHA 2FH3A 1M2VB 5KYWA 1AHQA 5FAEA 5A1MA 1MDUA 1AK6A 1PD1A 1KCQA 1SVQA 2HD7A 4JD2H 5KYYB 2FF6G 3EFOB 1NPHA 4KEDA 3FFKA 2XF1A 3A5NS 2MV2A 1D4XG 2D8BA 4CBXG 1SVRA 1X67A 4KEFA 1PCXA 3EH1A 5IVUA 1NMDG 1M2OA 1YVNG 1RGIG 1C0FS 1WM4A 1TMWA 2FH1A 3EG9A 3EGXA 1V6FA 2VIKA 3CIPG 2LLFA 5L6WC 2KVKA 1UDMA 1P8ZG 1D0NA 1Q8GA 1TVJA 1WNJA 2FH4A 5KYXB 1M2VA 1Q8XA 2NUPA 1T3XA 1T44G 1JHWA 3EH2A 5KYNA 3TU5B 1YAGG 4Z94G 3EGDB 5KYYA 1M4JA 2XFAA 4BEX1 4PKGG 3EFOA 4PKHB 1F7SA 3DAWB 1T2LA
chains in the Genus database with same CATH topology
2NUTB 5FAFA 2FF3A 3DA7A 3Q2BA 5KYWB 2FH2A 2W0IA 2LJ8A 1WFSA 1VFQA 1DEJS 5KYUA 5HVKB 1VKKA 4KEEA 4CBUG 1EQYS 3L50A 4CBWG 1QPVA 1T3YA 2NUPB 3A5OS 2L72A 2LXXA 3FG7A 3FG6A 4PKIG 1NM1G 3CJBG 5KYXA 3CJCG 1PD0A 4LIZA 2MP4A 1P8XA 1NLVG 1C0GS 2VACA 3FFNA 1HQZ1 2MOTA 3EG9B 3EGDA 3EGXB 1CFYA 3CI5G 5DD2A 1CNUA 2I2QA 1COFA 2QTVA 3A5LS 5HVKD 3A5MS 1AK7A 1SVYA 1ESVS 4S10C 1H1VG 5KYUB 2NUTA 1J72A 2VILA 2FGHA 2FH3A 1M2VB 5KYWA 1AHQA 5FAEA 5A1MA 1MDUA 1AK6A 1PD1A 1KCQA 1SVQA 2HD7A 4JD2H 5KYYB 2FF6G 3EFOB 1NPHA 4KEDA 3FFKA 2XF1A 3A5NS 2MV2A 1D4XG 2D8BA 4CBXG 1SVRA 1X67A 4KEFA 1PCXA 3EH1A 5IVUA 1NMDG 1M2OA 1YVNG 1RGIG 1C0FS 1WM4A 1TMWA 2FH1A 3EG9A 3EGXA 1V6FA 2VIKA 3CIPG 2LLFA 5L6WC 2KVKA 1UDMA 1P8ZG 1D0NA 1Q8GA 1TVJA 1WNJA 2FH4A 5KYXB 1M2VA 1Q8XA 2NUPA 1T3XA 1T44G 1JHWA 3EH2A 5KYNA 3TU5B 1YAGG 4Z94G 3EGDB 5KYYA 1M4JA 2XFAA 4BEX1 4PKGG 3EFOA 4PKHB 1F7SA 3DAWB 1T2LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NUT B;  5FAF A;  2FF3 A;  3Q2B A;  5KYW B;  2FH2 A;  2W0I A;  2LJ8 A;  1WFS A;  1VFQ A;  1DEJ S;  5KYU A;  5HVK B;  1VKK A;  4KEE A;  4CBU G;  1EQY S;  3L50 A;  4CBW G;  1QPV A;  1T3Y A;  2NUP B;  3A5O S;  2L72 A;  2LXX A;  3FG7 A;  3FG6 A;  4PKI G;  1NM1 G;  3CJB G;  5KYX A;  3CJC G;  1PD0 A;  4LIZ A;  2MP4 A;  1P8X A;  1NLV G;  1C0G S;  2VAC A;  3FFN A;  1HQZ 1;  2MOT A;  3EG9 B;  3EGD A;  3EGX B;  1CFY A;  3CI5 G;  5DD2 A;  1CNU A;  2I2Q A;  1COF A;  2QTV A;  3A5L S;  5HVK D;  3A5M S;  1AK7 A;  1SVY A;  1ESV S;  4S10 C;  1H1V G;  5KYU B;  2NUT A;  1J72 A;  2VIL A;  2FGH A;  2FH3 A;  1M2V B;  5KYW A;  1AHQ A;  5FAE A;  5A1M A;  1MDU A;  1AK6 A;  1PD1 A;  1KCQ A;  1SVQ A;  2HD7 A;  4JD2 H;  5KYY B;  2FF6 G;  3EFO B;  1NPH A;  4KED A;  3FFK A;  2XF1 A;  3A5N S;  2MV2 A;  1D4X G;  2D8B A;  4CBX G;  1SVR A;  1X67 A;  4KEF A;  1PCX A;  3EH1 A;  5IVU A;  1NMD G;  1M2O A;  1YVN G;  1RGI G;  1C0F S;  1WM4 A;  1TMW A;  2FH1 A;  3EG9 A;  3EGX A;  1V6F A;  2VIK A;  3CIP G;  2LLF A;  5L6W C;  2KVK A;  1UDM A;  1P8Z G;  1D0N A;  1Q8G A;  1TVJ A;  1WNJ A;  2FH4 A;  5KYX B;  1M2V A;  1Q8X A;  2NUP A;  1T3X A;  1T44 G;  1JHW A;  3EH2 A;  5KYN A;  3TU5 B;  1YAG G;  4Z94 G;  3EGD B;  5KYY A;  1M4J A;  2XFA A;  4BEX 1;  4PKG G;  3EFO A;  4PKH B;  1F7S A;  3DAW B;  1T2L A; 
#chains in the Genus database with same CATH topology
 2NUT B;  5FAF A;  2FF3 A;  3DA7 A;  3Q2B A;  5KYW B;  2FH2 A;  2W0I A;  2LJ8 A;  1WFS A;  1VFQ A;  1DEJ S;  5KYU A;  5HVK B;  1VKK A;  4KEE A;  4CBU G;  1EQY S;  3L50 A;  4CBW G;  1QPV A;  1T3Y A;  2NUP B;  3A5O S;  2L72 A;  2LXX A;  3FG7 A;  3FG6 A;  4PKI G;  1NM1 G;  3CJB G;  5KYX A;  3CJC G;  1PD0 A;  4LIZ A;  2MP4 A;  1P8X A;  1NLV G;  1C0G S;  2VAC A;  3FFN A;  1HQZ 1;  2MOT A;  3EG9 B;  3EGD A;  3EGX B;  1CFY A;  3CI5 G;  5DD2 A;  1CNU A;  2I2Q A;  1COF A;  2QTV A;  3A5L S;  5HVK D;  3A5M S;  1AK7 A;  1SVY A;  1ESV S;  4S10 C;  1H1V G;  5KYU B;  2NUT A;  1J72 A;  2VIL A;  2FGH A;  2FH3 A;  1M2V B;  5KYW A;  1AHQ A;  5FAE A;  5A1M A;  1MDU A;  1AK6 A;  1PD1 A;  1KCQ A;  1SVQ A;  2HD7 A;  4JD2 H;  5KYY B;  2FF6 G;  3EFO B;  1NPH A;  4KED A;  3FFK A;  2XF1 A;  3A5N S;  2MV2 A;  1D4X G;  2D8B A;  4CBX G;  1SVR A;  1X67 A;  4KEF A;  1PCX A;  3EH1 A;  5IVU A;  1NMD G;  1M2O A;  1YVN G;  1RGI G;  1C0F S;  1WM4 A;  1TMW A;  2FH1 A;  3EG9 A;  3EGX A;  1V6F A;  2VIK A;  3CIP G;  2LLF A;  5L6W C;  2KVK A;  1UDM A;  1P8Z G;  1D0N A;  1Q8G A;  1TVJ A;  1WNJ A;  2FH4 A;  5KYX B;  1M2V A;  1Q8X A;  2NUP A;  1T3X A;  1T44 G;  1JHW A;  3EH2 A;  5KYN A;  3TU5 B;  1YAG G;  4Z94 G;  3EGD B;  5KYY A;  1M4J A;  2XFA A;  4BEX 1;  4PKG G;  3EFO A;  4PKH B;  1F7S A;  3DAW B;  1T2L A; 
#chains in the Genus database with same CATH homology
 2NUT B;  5FAF A;  2FF3 A;  3DA7 A;  3Q2B A;  5KYW B;  2FH2 A;  2W0I A;  2LJ8 A;  1WFS A;  1VFQ A;  1DEJ S;  5KYU A;  5HVK B;  1VKK A;  4KEE A;  4CBU G;  1EQY S;  3L50 A;  4CBW G;  1QPV A;  1T3Y A;  2NUP B;  3A5O S;  2L72 A;  2LXX A;  3FG7 A;  3FG6 A;  4PKI G;  1NM1 G;  3CJB G;  5KYX A;  3CJC G;  1PD0 A;  4LIZ A;  2MP4 A;  1P8X A;  1NLV G;  1C0G S;  2VAC A;  3FFN A;  1HQZ 1;  2MOT A;  3EG9 B;  3EGD A;  3EGX B;  1CFY A;  3CI5 G;  5DD2 A;  1CNU A;  2I2Q A;  1COF A;  2QTV A;  3A5L S;  5HVK D;  3A5M S;  1AK7 A;  1SVY A;  1ESV S;  4S10 C;  1H1V G;  5KYU B;  2NUT A;  1J72 A;  2VIL A;  2FGH A;  2FH3 A;  1M2V B;  5KYW A;  1AHQ A;  5FAE A;  5A1M A;  1MDU A;  1AK6 A;  1PD1 A;  1KCQ A;  1SVQ A;  2HD7 A;  4JD2 H;  5KYY B;  2FF6 G;  3EFO B;  1NPH A;  4KED A;  3FFK A;  2XF1 A;  3A5N S;  2MV2 A;  1D4X G;  2D8B A;  4CBX G;  1SVR A;  1X67 A;  4KEF A;  1PCX A;  3EH1 A;  5IVU A;  1NMD G;  1M2O A;  1YVN G;  1RGI G;  1C0F S;  1WM4 A;  1TMW A;  2FH1 A;  3EG9 A;  3EGX A;  1V6F A;  2VIK A;  3CIP G;  2LLF A;  5L6W C;  2KVK A;  1UDM A;  1P8Z G;  1D0N A;  1Q8G A;  1TVJ A;  1WNJ A;  2FH4 A;  5KYX B;  1M2V A;  1Q8X A;  2NUP A;  1T3X A;  1T44 G;  1JHW A;  3EH2 A;  5KYN A;  3TU5 B;  1YAG G;  4Z94 G;  3EGD B;  5KYY A;  1M4J A;  2XFA A;  4BEX 1;  4PKG G;  3EFO A;  4PKH B;  1F7S A;  3DAW B;  1T2L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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