1SYQA

Human vinculin head domain vh1, residues 1-258, in complex with human talin's vinculin binding site 1, residues 607-636
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
259
structure length
259
Chain Sequence
HMPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for amplifying vinculin activation by talin
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords vinculin isoform VCL
total genus 109
structure length 259
sequence length 259
ec nomenclature
pdb deposition date 2004-04-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.230 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Alpha-catenin/vinculin-like 1syqA02
1.20.120.230 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Alpha-catenin/vinculin-like 1syqA01
2L7AA 2X0CA 5L0JA 1H6GA 1RKEA 1DOWA 2B0HA 1ZW2A 1SYQA 3H2UA 1ST6A 5L0FA 5L0GA 3TJ6A 3TJ5A 1YDIA 4P9TA 3ZDLA 4EHPA 4ONSA 5L0DA 3MYIA 2HSQA 1DOVA 4W8PA 3RF3A 2GWWA 1T01A 5L0CA 2GDCA 3T6GB 1U89A 4K1OA 1ZVZA 1RKEB 4PR9A 5FZTA 4E18A 1XWJA 1QKRA 1TR2A 3S90A 3VF0A 5L0IA 4E17A 3H2VA 4IGGA 1ZW3A 2LQGA 1L7CA 1U6HA 1RKCA 2IBFA 5L0HA 4DJ9A
chains in the Genus database with same CATH superfamily
3C18A 3K1IA 3GM3A 1LS4A 1PCXA 4O6YA 4AE4B 1M57C 1LPEA 2Q4FA 5A6AA 2Q7RA 5KYXB 1RCPA 2QE9A 2G3VA 1NU7D 4AK9A 4EIYA 5FCLA 2HKVA 3R2PA 5L0DA 2J7PD 4KNWA 1NU9C 4XTKA 4XPXA 4BJ6C 4FWVA 1KTMA 2CCYA 4YL0A 2WZGA 3GANA 3O10A 4AL0A 1U0BB 2DGJA 2PX0A 4HE8D 1D0ZA 3U0CA 4OIOF 1IZMA 2A1DD 2J8WA 1D0YA 4JC7A 2YLIA 2YKZA 3PMRA 3QMKA 1D1CA 4IWBA 1IW7F 3ABMC 2A6HF 3ZIBA 5D91A 5KYWA 2W45A 3DJUB 3JYHA 1JMWA 3KPHA 4FX5A 2IBFA 1BR2A 4P6IC 2EPMX 2XL6A 2OJED 1ZU5A 3DE9A 1GS9A 3EGXA 4DXWA 4CS9C 4NTAA 3C8GA 5L0FA 2E87A 4JURI 1D0XA 5JP7A 2AWYA 3FXHA 3S0XA 4JTDB 5BQGA 3VRCA 4BG0A 4C3EA 5AC5A 5KYYB 1HY5A 5CI9A 5BQHA 2IXOA 4LLEA 3AGUA 4HEAJ 3K1HA 3HNIA 4AE4A 3EGDB 2NUTA 3VAYA 1XWJA 1G5ZA 3CQZA 1RMVA 2OKUA 2CDQA 2NPUA 5KYXA 3W2VA 2WVQA 1VMAA 2KC3A 3NG1A 1WWPA 3DM5A 2YL1A 1L7CA 1U6HA 1O87A 4QDLA 2HUJA 1QVXA 3EH2A 3JZ0A 4YT2A 1BBHA 1VYIA 1RKEA 4E7ZA 4I1MA 1A7VA 3MYFA 1OKKA 3HLZA 5T3TA 2O9XA 4IARA 5L0GA 1TWCA 1LS1A 1F1MA 2J9BA 2NSGA 4O6NA 2ZXPA 4H4KC 3GM1A 4LDRA 5EHHA 1JR8A 3NDBB 4XLPF 3AG1C 4G78A 1DOVA 2P0NA 4PJMA 1FFHA 3SXMA 2GDCA 2AP3A 4K7BA 3L0IA 1KNYA 5GPGB 3ZTZA 1NG1A 4G7OF 4PR9A 5D92A 4MQ9F 3SXKA 1RJ9A 3ZVRA 4JW1A 3QVZA 1ZHWA 1M2VB 1QKRA 3L8IA 3WHNA 4BJ5C 1PD0A 2KJGA 2C04A 2LSEA 4DRHB 5KYUB 1WGWA 4Q7CA 4DVZA 3O6XA 3S84A 1OCZC 3B9QA 2H7VC 1LVKA 1QSPA 3MBGA 2ETSA 4XWJA 3FAPB 1G4US 4U9EA 3U5SA 5BQIA 1BR1A 2RD9A 1HE9A 2EIMC 3QTHA 4PJLA 3KKBA 1Z6AA 3F47A 2XLWA 2CYDA 2CGEA 3GORA 3UGPA 1T9KA 3TD7A 2WVNA 3JT1A 2A0BA 4RDAA 3U2MA 3DJNB 1QZXA 2CNWA 2HSBA 4U5DE 3DWWA 4MTOA 4O79A 3S27A 3T6GB 2J45A 3W2WA 3G4XA 1OW6A 4G0HA 2HJMA 2WZLA 3UMKA 1LE4A 4I1OB 2J9VA 2XLHA 2WZFA 4E17A 4U5GA 2LFDA 3KYIA 3H2VA 1EA8A 1AUEA 2P1AA 2XRHA 2HV6A 2XL4A 4G7ZF 3NKDA 2R7UA 1Q0MA 2J46A 3JSEO 4MTFA 1OCRC 2HFIA 2Y39A 3OA1A 1S7ZA 4PFPA 5DQZA 1M6TA 1R5ID 1VB5A 3EJNA 4Z9IA 1BDJB 4NCQA 4CDYA 2DB4A 1OQCA 2PNOA 3QW1A 5BUOA 5KYWB 2GAQA 1HE1A 3W8HA 1NSGB 5JT4A 2YL3A 3HKKA 2XL8A 4PACA 3J06A 3DI5A 3DKAA 4N4WA 2QTVA 1WN0A 1S05A 2DYSC 3E9VA 4FAPB 3AG2C 1UG7A 3EGXB 1WOLA 4MVOA 3C8GB 4AL1A 4BEJA 4PK4A 3K7DA 1E86A 1M2OA 2L6HA 2LQGA 5COGA 3JYYA 4XLNF 3RFYA 4NTBA 1C03A 2R7XA 2L7AA 1HMOA 2ZXOA 3GEIA 3U8VA 3PDMP 3EZHA 4U5HA 2WB7A 4Z9HA 2YLDA 4IAOA 4JCHA 3IQTA 2NUTB 2W4MA 2R7VA 2VASA 5DQTA 4CS8C 3M4CA 4EUKB 2L81A 4XPWA 3A9CA 3IHUA 3RW0A 1APCA 1E2XA 3VYWA 2JD3A 3FVYA 3HNKA 4U5EE 4WJ0A 3OEOA 3B0VC 3DD7A 3HNJA 4JTAB 1CGME 4CBEA 2XM0A 1RKEB 2R7WA 1VK5A 3EHNA 1QQ3A 3NMIA 2LK4A 1TR2A 3DXJF 2LD6A 4IRUA 4J7YA 4JE9A 4YL3A 1OW7A 5EK0A 1T6IA 3C62A 1VOMA 3UR3C 2HMQA 1MMNA 4RD9A 5K0IA 1D1BA 3GM2A 1LE2A 5L0HA 4HFKB 1ZHYA 3LS0A 3SYNA 2UUHA 2UUIA 1O5HA 1OR2A 2HS5A 1RJ9B 3FOPA 3HTKC 3LAYA 1C17M 2VH3A 4JCZA 1K05A 3QW0A 1AEPA 5F28E 1MNDA 3AGTA 4DRJB 1ORYA 1MNEA 1WTYA 4P9TA 4A4AA 3U8PA 1SF8A 3SNHA 2A6EF 4YK5A 4DVYP 3CAXA 1T5OA 3SXZA 3NMKA 3ECSA 2OQMA 2QNLA 1OXKA 2KW3C 2MHRA 3R7CA 4CSAA 4NY3A 1U89A 1TWHA 1J8MF 4LLCA 3TQOA 4JTCB 3E70C 3TOMA 2PP4A 1FMVA 1ZZPA 4HFFB 4N6CA 1ZHXA 2YRFA 4JJGA 1LI7A 3GWNA 1E85A 2R7SA 4CJGA 4U5CE 2VCCA 3WODF 4E7SA 2J9UA 4DOZA 4N6HA 1FNTc 3UNGC 3LLIA 256BA 1A7EA 5KYNA 4KC9A 4CIPA 3K1IC 3RIPA 2I8BA 4I44A 3ABLC 4BPMA 3C7JA 4OD5A 4D4XA 5L3VA 4MVUA 3W8IA 3T4RA 4JZAA 1T01A 4J32B 3AQCA 2L9JA 3C8GD 1PD1A 3LEVA 3WG7C 1SMYF 2VCAA 3K33A 5E2QA 3QZCA 4E18A 4YT4A 2B0JA 1TQGA 2ASRA 5T1DB 1ZHTA 2IM8A 2Q00A 2Y3BA 4U9DA 3UMIA 5L0IA 4K0DA 2MWQA 1XZPA 3L8JA 4DBRA 2LFFA 1Q0GA 3B0UX 1YAUO 2AU5A 1YARO 2OEXA 1YZAA 2EILC 2Q9BA 3LEOA 3GEHA 3EHMA 4NTFA 3RVZA 1V54C 2EINC 2BL2A 3KYJA 3AJMA 1Y4CA 4I3MA 3U2LA 4BJTA 1QPUA 2ICWG 4LACB 4MNDA 3RQEA 3WAQA 1E83A 3AQBA 4ONSA 3IPMO 1OKKD 5JRAA 2GWWA 3X1OA 2HMZA 1TWAA 3ITFA 4OD4A 2PF4E 2R25A 2VC9A 1JPNA 1TWGA 1ZU4A 3VM6A 2J9WA 4PJNA 4JKVA 3RH3A 3C8ZA 2R7OA 2Y3DA 1Z23A 3DZAA 2QUPA 3VF0A 2LP4A 3ABKC 5B1AC 3EG9A 3LS1A 4EKWA 5HV9A 2R05A 2J0XA 4OIQF 3V5YA 4ULWA 4EBJA 1EI7A 4R32A 4G7HF 3N2ZB 1BR4A 3I5QA 5EGYA 1V55C 2IXPA 5AC4A 2GFHA 2F22A 3AOUA 1G4WR 4C7OB 3MFNA 1OCOC 2JX0A 2Y3GA 3NMJA 2YQYA 4QI2A 1DOWA 4CX9A 5A6BA 1SYQA 5TJ5E 1JAFA 2FAPB 2YHSA 4OIPF 4BJ6A 4GEHA 1NFOA 1EQ1A 2C03A 3O55A 4PJJA 2HV7A 2XXAA 4OINF 5A69A 1MMAA 2HSQA 4Q4ZF 1ZYRF 2KYHA 1WATA 3DAFA 3IEEA 4JJFA 1V74B 5HSWA 2R7RA 2MYSA 2CNWD 4EWCA 2YL7A 3N0TA 3SZRA 1FMWA 5COFA 2OEVA 3FHDA 1Z5ZA 3RKOF 1YYJA 1FTSA 2IYLD 4ANJA 3KL4A 3L1MA 1TFKB 1MMGA 3GEEA 2R7TA 1C02A 1D1AA 4MW8A 2OJQA 3LUTB 3V5XA 3SP1A 4CS9A 5JSLA 1E84A 1ZW2A 3EFOA 1EKYA 2GA0A 1ST6A 3GODA 4O6MA 3TJ5A 3B71A 1LI5A 4MVSA 1MQVA 4QI0A 2NUPA 1OCCC 2BE5F 2V3CC 2OOCA 4C7OA 1H7IA 3LJBA 4UDVA 1VLSA 4MVQA 3BRJA 1JPJA 2AVKA 4X0RA 4DBQA 2V26A 3V5ZA 1VYKA 4F4BA 3S90A 2XM4A 2YL0A 3V7OA 3US6A 2A68F 5B1BC 2Z15A 2PX3A 2XLOA 1ZW3A 3PHF2 5L0JA 4CS7A 2HJ3A 3HJCA 5IY5C 3LESA 1PV3A 2R03A 2YWAA 4JEBA 2CW0F 3AG4C 1I5NA 1AVOB 2XLDA 2KNHA 2OG2A 5AGFA 2LCHA 3RQGA 2YLGA 1A0BA 3B29A 3FAJA 4CIHA 4XEFA 3SXYA 5B3IA 2FFHA 5L3QA 2VB6A 2OCCC 4Q5SF 3JRMO 2H7BA 2XSEA 5DS6A 1W2WA 1Z3IX 1A7DA 4EBBA 2IXNA 1FFTC 3MX3A 4MS2A 4JEAA 1OR3A 2Q3TA 4BJ5A 3G50A 1XZQA 4P9FA 3UMHA 1V4AA 1TKNA 3RYLA 5B3SC 3FMSA 3JRTA 1ORSC 2AWCA 1Q0DA 2R9RB 3O39A 3ASOC 3F46A 5JS5A 3GWLA 1NZEA 3LLKA 4LDKA 3RVYA 2G62A 1CPRA 2PBEA 1YYXA 3JCUQ 2L6GA 4Z9JA 4MTGA 2FGYA 3EPVA 3QVYA 1NLXA 5DS5A 1Q0KA 3JSZA 3X2QC 1TFOB 3I4UA 3N24A 4XQ1A 2WL8A 3ZTMA 3EG9B 2A69F 4MVMA 4U5FE 4ULVA 3LNRA 4A2NB 3SEOA 1L3PA 1T6UA 1YA7O 2KGOA 1K40A 1Z7Qc 4C3BA 5KYYA 4L6RA 3U3BA 1YJGA 2EPNA 3ZG1A 4ER9A 2W4BA 1HMDA 3L34A 3U9MA 5A6JA 2R7QA 1A41A 1G8XA 2H7OA 1KU2A 2QY9A 2XS8A 3BEHA 2DYRC 2EPLX 4NQFA 3NKEA 4WGYA 3W4YA 1OXBA 4IJJA 4EBKA 1K04A 1MMDA 2G3KA 4BJ1A 3TULA 2PFDA 4GYTA 3HNLA 2XXAB 1M56C 5E33A 2I15A 3NYJA 3EH1A 2X0CA 4E0IA 3FOOA 4DRIB 2RSEB 2W9YA 1BZ4A 3DE8A 4LDQA 1JOGA 4NC3A 3IQCA 4GQHA 1H9GA 3KH2A 3IQ5A 3T6BA 1FR0A 3ZQYA 3TJ6A 2X51A 4MVRA 3ATPA 1B68A 2IXMA 5COMA 3M4BA 4IAQA 3NYLA 3CEXA 1YVIA 2WVOA 3ASNC 2A0UA 4M63A 4W8PA 3AG3C 5E3CA 3TK0A 1RXQA 1N1CA 2LIGA 5DS4A 2ZD9A 2L6FA 3Q6NA 5T3WA 5CI8A 4CJOA 1FAPB 4K1OA 1ZVZA 1JRAA 2XLMA 1I4ZA 3Q6MA 2HZ8A 1SZIA 4CSAC 1I4YA 3EFOB 5JLIA 1ORJA 2EIKC 3IQ6A 3T9OA 3DAGA 1T6QA 1Z63A 3MLGA 2JPUA 2Y69C 4CDVA 2Y3HA 4KNVA 3POVA 1YZCA 4JRZA 1CGNA 1WASA 2KSFA 2M4EA 2OU6A 2NUPB 1SR2A 4WABA 3JTLO 2P7VA 4O7GA 4YT5A 3S9OA 3NYMA 2EPOA 4D4NA 4CS8A 2YVKA 3ZWIA 4CDAA 2KK1A 3EGDA 2Q9CA 4FESA 4E0HA 2B0HA 2P61A 1NBBA 5A6KA 4KI2A 2XS1A 4C3DA 2D5RB 4MW3A 3H65A 2D4UA 3C63A 1YDIA 3LNMB 3ZDLA 4EHPA 4AX2A 4ZLCA 3MYIA 3DM9B 4YN0B 4N06A 5JVEA 1H9TA 3A11A 2ZXRA 3EZIA 4W8KA 3ZSUA 1Q0FA 1GQAA 2IOQA 1Y6DA 1J8YF 3K66A 5FZTA 3ZC4A 4YL1A 3K6BA 1YLMA 2EIJC 4XEKA 3B0PA 1OW8A 2ZPAA 2XLEA 3OWTA 2KQ9A 4IB4A 4OIRF 2VCBA 3S28A 2EPKX 1LM3B 1R4TA 1UFBA 1VLTA 4LERA 3TOLA 3S29A 1RKCA 2XLVA 3U3FA 4DJ9A 2BC5A 3G4ZA 3RQFA 2H8AA 3NRHA 4JVSA 4U5BE 3T6JA 1H6GA 1GGQA 5F5HA 4WGZA 1GM5A 4ZLDA 1M2VA 1QLEC 4H54A 2J7PA 1YA9A 3H2UA 3KMIA 1NFNA 2M64A 3EQLF 3Q7LA 4RBNA 3DMDA 5KYUA 3U9JA 4J30B 1HW2A 4JIOA 2TMVP 2QLAA 1LIHA 2ZXWC 5A6BD 2P6VA 2YZSA 5F5FA 2NG1A 3RF3A 4YT8A 5JUAA 5L0CA 3PCVA 4KBLA 2R02A 3M1CB 3Q7GA 2DI3A 4PFOA 1O3UA 5DLJA 4B6IA 1CGOA 1CPQA 2Q9AA 4J7TA 5DVWA 5E3AA 3FDQA 3I5PA 3UGOA 2YEVA 1ZHZA 2J0WA 3ZQVA 4BEMJ 4XPYA 2NSFA 3M15A 4IGGA 1LKXA 3M79A 4XEVA 4YJWA 5CIVA 1VTMP 4YWQA 1HW1A 3CSKA 4MVZA 3CZ6A
chains in the Genus database with same CATH topology
2L7AA 2X0CA 5L0JA 1H6GA 1RKEA 1DOWA 2B0HA 1ZW2A 1SYQA 3H2UA 1ST6A 5L0FA 5L0GA 3TJ6A 3TJ5A 1YDIA 4P9TA 3ZDLA 4EHPA 4ONSA 5L0DA 3MYIA 2HSQA 1DOVA 4W8PA 3RF3A 2GWWA 1T01A 5L0CA 2GDCA 3T6GB 1U89A 4K1OA 1ZVZA 1RKEB 4PR9A 5FZTA 4E18A 1XWJA 1QKRA 1TR2A 3S90A 3VF0A 5L0IA 4E17A 3H2VA 4IGGA 1ZW3A 2LQGA 1L7CA 1U6HA 1RKCA 2IBFA 5L0HA 4DJ9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L7A A;  2X0C A;  5L0J A;  1H6G A;  1RKE A;  1DOW A;  2B0H A;  1ZW2 A;  1SYQ A;  3H2U A;  1ST6 A;  5L0F A;  5L0G A;  3TJ6 A;  3TJ5 A;  1YDI A;  4P9T A;  3ZDL A;  4EHP A;  4ONS A;  5L0D A;  3MYI A;  2HSQ A;  1DOV A;  4W8P A;  3RF3 A;  2GWW A;  1T01 A;  5L0C A;  2GDC A;  3T6G B;  1U89 A;  4K1O A;  1ZVZ A;  1RKE B;  4PR9 A;  5FZT A;  4E18 A;  1XWJ A;  1QKR A;  1TR2 A;  3S90 A;  3VF0 A;  5L0I A;  4E17 A;  3H2V A;  4IGG A;  1ZW3 A;  2LQG A;  1L7C A;  1U6H A;  1RKC A;  2IBF A;  5L0H A;  4DJ9 A; 
#chains in the Genus database with same CATH topology
 3C18 A;  3K1I A;  3GM3 A;  1LS4 A;  1PCX A;  4O6Y A;  4AE4 B;  1M57 C;  1LPE A;  2Q4F A;  5A6A A;  2Q7R A;  5KYX B;  1RCP A;  2QE9 A;  2G3V A;  1NU7 D;  4AK9 A;  4EIY A;  5FCL A;  2HKV A;  3R2P A;  5L0D A;  2J7P D;  4KNW A;  1NU9 C;  4XTK A;  4XPX A;  4BJ6 C;  4FWV A;  1KTM A;  2CCY A;  4YL0 A;  2WZG A;  3GAN A;  3O10 A;  4AL0 A;  1U0B B;  2DGJ A;  2PX0 A;  4HE8 D;  1D0Z A;  3U0C A;  4OIO F;  1IZM A;  2A1D D;  2J8W A;  1D0Y A;  4JC7 A;  2YLI A;  2YKZ A;  3PMR A;  3QMK A;  1D1C A;  4IWB A;  1IW7 F;  3ABM C;  2A6H F;  3ZIB A;  5D91 A;  5KYW A;  2W45 A;  3DJU B;  3JYH A;  1JMW A;  3KPH A;  4FX5 A;  2IBF A;  1BR2 A;  4P6I C;  2EPM X;  2XL6 A;  2OJE D;  1ZU5 A;  3DE9 A;  1GS9 A;  3EGX A;  4DXW A;  4CS9 C;  4NTA A;  3C8G A;  5L0F A;  2E87 A;  4JUR I;  1D0X A;  5JP7 A;  2AWY A;  3FXH A;  3S0X A;  4JTD B;  5BQG A;  3VRC A;  4BG0 A;  4C3E A;  5AC5 A;  5KYY B;  1HY5 A;  5CI9 A;  5BQH A;  2IXO A;  4LLE A;  3AGU A;  4HEA J;  3K1H A;  3HNI A;  4AE4 A;  3EGD B;  2NUT A;  3VAY A;  1XWJ A;  1G5Z A;  3CQZ A;  1RMV A;  2OKU A;  2CDQ A;  2NPU A;  5KYX A;  3W2V A;  2WVQ A;  1VMA A;  2KC3 A;  3NG1 A;  1WWP A;  3DM5 A;  2YL1 A;  1L7C A;  1U6H A;  1O87 A;  4QDL A;  2HUJ A;  1QVX A;  3EH2 A;  3JZ0 A;  4YT2 A;  1BBH A;  1VYI A;  1RKE A;  4E7Z A;  4I1M A;  1A7V A;  3MYF A;  1OKK A;  3HLZ A;  5T3T A;  2O9X A;  4IAR A;  5L0G A;  1TWC A;  1LS1 A;  1F1M A;  2J9B A;  2NSG A;  4O6N A;  2ZXP A;  4H4K C;  3GM1 A;  4LDR A;  5EHH A;  1JR8 A;  3NDB B;  4XLP F;  3AG1 C;  4G78 A;  1DOV A;  2P0N A;  4PJM A;  1FFH A;  3SXM A;  2GDC A;  2AP3 A;  4K7B A;  3L0I A;  1KNY A;  5GPG B;  3ZTZ A;  1NG1 A;  4G7O F;  4PR9 A;  5D92 A;  4MQ9 F;  3SXK A;  1RJ9 A;  3ZVR A;  4JW1 A;  3QVZ A;  1ZHW A;  1M2V B;  1QKR A;  3L8I A;  3WHN A;  4BJ5 C;  1PD0 A;  2KJG A;  2C04 A;  2LSE A;  4DRH B;  5KYU B;  1WGW A;  4Q7C A;  4DVZ A;  3O6X A;  3S84 A;  1OCZ C;  3B9Q A;  2H7V C;  1LVK A;  1QSP A;  3MBG A;  2ETS A;  4XWJ A;  3FAP B;  1G4U S;  4U9E A;  3U5S A;  5BQI A;  1BR1 A;  2RD9 A;  1HE9 A;  2EIM C;  3QTH A;  4PJL A;  3KKB A;  1Z6A A;  3F47 A;  2XLW A;  2CYD A;  2CGE A;  3GOR A;  3UGP A;  1T9K A;  3TD7 A;  2WVN A;  3JT1 A;  2A0B A;  4RDA A;  3U2M A;  3DJN B;  1QZX A;  2CNW A;  2HSB A;  4U5D E;  3DWW A;  4MTO A;  4O79 A;  3S27 A;  3T6G B;  2J45 A;  3W2W A;  3G4X A;  1OW6 A;  4G0H A;  2HJM A;  2WZL A;  3UMK A;  1LE4 A;  4I1O B;  2J9V A;  2XLH A;  2WZF A;  4E17 A;  4U5G A;  2LFD A;  3KYI A;  3H2V A;  1EA8 A;  1AUE A;  2P1A A;  2XRH A;  2HV6 A;  2XL4 A;  4G7Z F;  3NKD A;  2R7U A;  1Q0M A;  2J46 A;  3JSE O;  4MTF A;  1OCR C;  2HFI A;  2Y39 A;  3OA1 A;  1S7Z A;  4PFP A;  5DQZ A;  1M6T A;  1R5I D;  1VB5 A;  3EJN A;  4Z9I A;  1BDJ B;  4NCQ A;  4CDY A;  2DB4 A;  1OQC A;  2PNO A;  3QW1 A;  5BUO A;  5KYW B;  2GAQ A;  1HE1 A;  3W8H A;  1NSG B;  5JT4 A;  2YL3 A;  3HKK A;  2XL8 A;  4PAC A;  3J06 A;  3DI5 A;  3DKA A;  4N4W A;  2QTV A;  1WN0 A;  1S05 A;  2DYS C;  3E9V A;  4FAP B;  3AG2 C;  1UG7 A;  3EGX B;  1WOL A;  4MVO A;  3C8G B;  4AL1 A;  4BEJ A;  4PK4 A;  3K7D A;  1E86 A;  1M2O A;  2L6H A;  2LQG A;  5COG A;  3JYY A;  4XLN F;  3RFY A;  4NTB A;  1C03 A;  2R7X A;  2L7A A;  1HMO A;  2ZXO A;  3GEI A;  3U8V A;  3PDM P;  3EZH A;  4U5H A;  2WB7 A;  4Z9H A;  2YLD A;  4IAO A;  4JCH A;  3IQT A;  2NUT B;  2W4M A;  2R7V A;  2VAS A;  5DQT A;  4CS8 C;  3M4C A;  4EUK B;  2L81 A;  4XPW A;  3A9C A;  3IHU A;  3RW0 A;  1APC A;  1E2X A;  3VYW A;  2JD3 A;  3FVY A;  3HNK A;  4U5E E;  4WJ0 A;  3OEO A;  3B0V C;  3DD7 A;  3HNJ A;  4JTA B;  1CGM E;  4CBE A;  2XM0 A;  1RKE B;  2R7W A;  1VK5 A;  3EHN A;  1QQ3 A;  3NMI A;  2LK4 A;  1TR2 A;  3DXJ F;  2LD6 A;  4IRU A;  4J7Y A;  4JE9 A;  4YL3 A;  1OW7 A;  5EK0 A;  1T6I A;  3C62 A;  1VOM A;  3UR3 C;  2HMQ A;  1MMN A;  4RD9 A;  5K0I A;  1D1B A;  3GM2 A;  1LE2 A;  5L0H A;  4HFK B;  1ZHY A;  3LS0 A;  3SYN A;  2UUH A;  2UUI A;  1O5H A;  1OR2 A;  2HS5 A;  1RJ9 B;  3FOP A;  3HTK C;  3LAY A;  1C17 M;  2VH3 A;  4JCZ A;  1K05 A;  3QW0 A;  1AEP A;  5F28 E;  1MND A;  3AGT A;  4DRJ B;  1ORY A;  1MNE A;  1WTY A;  4P9T A;  4A4A A;  3U8P A;  1SF8 A;  3SNH A;  2A6E F;  4YK5 A;  4DVY P;  3CAX A;  1T5O A;  3SXZ A;  3NMK A;  3ECS A;  2OQM A;  2QNL A;  1OXK A;  2KW3 C;  2MHR A;  3R7C A;  4CSA A;  4NY3 A;  1U89 A;  1TWH A;  1J8M F;  4LLC A;  3TQO A;  4JTC B;  3E70 C;  3TOM A;  2PP4 A;  1FMV A;  1ZZP A;  4HFF B;  4N6C A;  1ZHX A;  2YRF A;  4JJG A;  1LI7 A;  3GWN A;  1E85 A;  2R7S A;  4CJG A;  4U5C E;  2VCC A;  3WOD F;  4E7S A;  2J9U A;  4DOZ A;  4N6H A;  1FNT c;  3UNG C;  3LLI A;  256B A;  1A7E A;  5KYN A;  4KC9 A;  4CIP A;  3K1I C;  3RIP A;  2I8B A;  4I44 A;  3ABL C;  4BPM A;  3C7J A;  4OD5 A;  4D4X A;  5L3V A;  4MVU A;  3W8I A;  3T4R A;  4JZA A;  1T01 A;  4J32 B;  3AQC A;  2L9J A;  3C8G D;  1PD1 A;  3LEV A;  3WG7 C;  1SMY F;  2VCA A;  3K33 A;  5E2Q A;  3QZC A;  4E18 A;  4YT4 A;  2B0J A;  1TQG A;  2ASR A;  5T1D B;  1ZHT A;  2IM8 A;  2Q00 A;  2Y3B A;  4U9D A;  3UMI A;  5L0I A;  4K0D A;  2MWQ A;  1XZP A;  3L8J A;  4DBR A;  2LFF A;  1Q0G A;  3B0U X;  1YAU O;  2AU5 A;  1YAR O;  2OEX A;  1YZA A;  2EIL C;  2Q9B A;  3LEO A;  3GEH A;  3EHM A;  4NTF A;  3RVZ A;  1V54 C;  2EIN C;  2BL2 A;  3KYJ A;  3AJM A;  1Y4C A;  4I3M A;  3U2L A;  4BJT A;  1QPU A;  2ICW G;  4LAC B;  4MND A;  3RQE A;  3WAQ A;  1E83 A;  3AQB A;  4ONS A;  3IPM O;  1OKK D;  5JRA A;  2GWW A;  3X1O A;  2HMZ A;  1TWA A;  3ITF A;  4OD4 A;  2PF4 E;  2R25 A;  2VC9 A;  1JPN A;  1TWG A;  1ZU4 A;  3VM6 A;  2J9W A;  4PJN A;  4JKV A;  3RH3 A;  3C8Z A;  2R7O A;  2Y3D A;  1Z23 A;  3DZA A;  2QUP A;  3VF0 A;  2LP4 A;  3ABK C;  5B1A C;  3EG9 A;  3LS1 A;  4EKW A;  5HV9 A;  2R05 A;  2J0X A;  4OIQ F;  3V5Y A;  4ULW A;  4EBJ A;  1EI7 A;  4R32 A;  4G7H F;  3N2Z B;  1BR4 A;  3I5Q A;  5EGY A;  1V55 C;  2IXP A;  5AC4 A;  2GFH A;  2F22 A;  3AOU A;  1G4W R;  4C7O B;  3MFN A;  1OCO C;  2JX0 A;  2Y3G A;  3NMJ A;  2YQY A;  4QI2 A;  1DOW A;  4CX9 A;  5A6B A;  1SYQ A;  5TJ5 E;  1JAF A;  2FAP B;  2YHS A;  4OIP F;  4BJ6 A;  4GEH A;  1NFO A;  1EQ1 A;  2C03 A;  3O55 A;  4PJJ A;  2HV7 A;  2XXA A;  4OIN F;  5A69 A;  1MMA A;  2HSQ A;  4Q4Z F;  1ZYR F;  2KYH A;  1WAT A;  3DAF A;  3IEE A;  4JJF A;  1V74 B;  5HSW A;  2R7R A;  2MYS A;  2CNW D;  4EWC A;  2YL7 A;  3N0T A;  3SZR A;  1FMW A;  5COF A;  2OEV A;  3FHD A;  1Z5Z A;  3RKO F;  1YYJ A;  1FTS A;  2IYL D;  4ANJ A;  3KL4 A;  3L1M A;  1TFK B;  1MMG A;  3GEE A;  2R7T A;  1C02 A;  1D1A A;  4MW8 A;  2OJQ A;  3LUT B;  3V5X A;  3SP1 A;  4CS9 A;  5JSL A;  1E84 A;  1ZW2 A;  3EFO A;  1EKY A;  2GA0 A;  1ST6 A;  3GOD A;  4O6M A;  3TJ5 A;  3B71 A;  1LI5 A;  4MVS A;  1MQV A;  4QI0 A;  2NUP A;  1OCC C;  2BE5 F;  2V3C C;  2OOC A;  4C7O A;  1H7I A;  3LJB A;  4UDV A;  1VLS A;  4MVQ A;  3BRJ A;  1JPJ A;  2AVK A;  4X0R A;  4DBQ A;  2V26 A;  3V5Z A;  1VYK A;  4F4B A;  3S90 A;  2XM4 A;  2YL0 A;  3V7O A;  3US6 A;  2A68 F;  5B1B C;  2Z15 A;  2PX3 A;  2XLO A;  1ZW3 A;  3PHF 2;  5L0J A;  4CS7 A;  2HJ3 A;  3HJC A;  5IY5 C;  3LES A;  1PV3 A;  2R03 A;  2YWA A;  4JEB A;  2CW0 F;  3AG4 C;  1I5N A;  1AVO B;  2XLD A;  2KNH A;  2OG2 A;  5AGF A;  2LCH A;  3RQG A;  2YLG A;  1A0B A;  3B29 A;  3FAJ A;  4CIH A;  4XEF A;  3SXY A;  5B3I A;  2FFH A;  5L3Q A;  2VB6 A;  2OCC C;  4Q5S F;  3JRM O;  2H7B A;  2XSE A;  5DS6 A;  1W2W A;  1Z3I X;  1A7D A;  4EBB A;  2IXN A;  1FFT C;  3MX3 A;  4MS2 A;  4JEA A;  1OR3 A;  2Q3T A;  4BJ5 A;  3G50 A;  1XZQ A;  4P9F A;  3UMH A;  1V4A A;  1TKN A;  3RYL A;  5B3S C;  3FMS A;  3JRT A;  1ORS C;  2AWC A;  1Q0D A;  2R9R B;  3O39 A;  3ASO C;  3F46 A;  5JS5 A;  3GWL A;  1NZE A;  3LLK A;  4LDK A;  3RVY A;  2G62 A;  1CPR A;  2PBE A;  1YYX A;  3JCU Q;  2L6G A;  4Z9J A;  4MTG A;  2FGY A;  3EPV A;  3QVY A;  1NLX A;  5DS5 A;  1Q0K A;  3JSZ A;  3X2Q C;  1TFO B;  3I4U A;  3N24 A;  4XQ1 A;  2WL8 A;  3ZTM A;  3EG9 B;  2A69 F;  4MVM A;  4U5F E;  4ULV A;  3LNR A;  4A2N B;  3SEO A;  1L3P A;  1T6U A;  1YA7 O;  2KGO A;  1K40 A;  1Z7Q c;  4C3B A;  5KYY A;  4L6R A;  3U3B A;  1YJG A;  2EPN A;  3ZG1 A;  4ER9 A;  2W4B A;  1HMD A;  3L34 A;  3U9M A;  5A6J A;  2R7Q A;  1A41 A;  1G8X A;  2H7O A;  1KU2 A;  2QY9 A;  2XS8 A;  3BEH A;  2DYR C;  2EPL X;  4NQF A;  3NKE A;  4WGY A;  3W4Y A;  1OXB A;  4IJJ A;  4EBK A;  1K04 A;  1MMD A;  2G3K A;  4BJ1 A;  3TUL A;  2PFD A;  4GYT A;  3HNL A;  2XXA B;  1M56 C;  5E33 A;  2I15 A;  3NYJ A;  3EH1 A;  2X0C A;  4E0I A;  3FOO A;  4DRI B;  2RSE B;  2W9Y A;  1BZ4 A;  3DE8 A;  4LDQ A;  1JOG A;  4NC3 A;  3IQC A;  4GQH A;  1H9G A;  3KH2 A;  3IQ5 A;  3T6B A;  1FR0 A;  3ZQY A;  3TJ6 A;  2X51 A;  4MVR A;  3ATP A;  1B68 A;  2IXM A;  5COM A;  3M4B A;  4IAQ A;  3NYL A;  3CEX A;  1YVI A;  2WVO A;  3ASN C;  2A0U A;  4M63 A;  4W8P A;  3AG3 C;  5E3C A;  3TK0 A;  1RXQ A;  1N1C A;  2LIG A;  5DS4 A;  2ZD9 A;  2L6F A;  3Q6N A;  5T3W A;  5CI8 A;  4CJO A;  1FAP B;  4K1O A;  1ZVZ A;  1JRA A;  2XLM A;  1I4Z A;  3Q6M A;  2HZ8 A;  1SZI A;  4CSA C;  1I4Y A;  3EFO B;  5JLI A;  1ORJ A;  2EIK C;  3IQ6 A;  3T9O A;  3DAG A;  1T6Q A;  1Z63 A;  3MLG A;  2JPU A;  2Y69 C;  4CDV A;  2Y3H A;  4KNV A;  3POV A;  1YZC A;  4JRZ A;  1CGN A;  1WAS A;  2KSF A;  2M4E A;  2OU6 A;  2NUP B;  1SR2 A;  4WAB A;  3JTL O;  2P7V A;  4O7G A;  4YT5 A;  3S9O A;  3NYM A;  2EPO A;  4D4N A;  4CS8 A;  2YVK A;  3ZWI A;  4CDA A;  2KK1 A;  3EGD A;  2Q9C A;  4FES A;  4E0H A;  2B0H A;  2P61 A;  1NBB A;  5A6K A;  4KI2 A;  2XS1 A;  4C3D A;  2D5R B;  4MW3 A;  3H65 A;  2D4U A;  3C63 A;  1YDI A;  3LNM B;  3ZDL A;  4EHP A;  4AX2 A;  4ZLC A;  3MYI A;  3DM9 B;  4YN0 B;  4N06 A;  5JVE A;  1H9T A;  3A11 A;  2ZXR A;  3EZI A;  4W8K A;  3ZSU A;  1Q0F A;  1GQA A;  2IOQ A;  1Y6D A;  1J8Y F;  3K66 A;  5FZT A;  3ZC4 A;  4YL1 A;  3K6B A;  1YLM A;  2EIJ C;  4XEK A;  3B0P A;  1OW8 A;  2ZPA A;  2XLE A;  3OWT A;  2KQ9 A;  4IB4 A;  4OIR F;  2VCB A;  3S28 A;  2EPK X;  1LM3 B;  1R4T A;  1UFB A;  1VLT A;  4LER A;  3TOL A;  3S29 A;  1RKC A;  2XLV A;  3U3F A;  4DJ9 A;  2BC5 A;  3G4Z A;  3RQF A;  2H8A A;  3NRH A;  4JVS A;  4U5B E;  3T6J A;  1H6G A;  1GGQ A;  5F5H A;  4WGZ A;  1GM5 A;  4ZLD A;  1M2V A;  1QLE C;  4H54 A;  2J7P A;  1YA9 A;  3H2U A;  3KMI A;  1NFN A;  2M64 A;  3EQL F;  3Q7L A;  4RBN A;  3DMD A;  5KYU A;  3U9J A;  4J30 B;  1HW2 A;  4JIO A;  2TMV P;  2QLA A;  1LIH A;  2ZXW C;  5A6B D;  2P6V A;  2YZS A;  5F5F A;  2NG1 A;  3RF3 A;  4YT8 A;  5JUA A;  5L0C A;  3PCV A;  4KBL A;  2R02 A;  3M1C B;  3Q7G A;  2DI3 A;  4PFO A;  1O3U A;  5DLJ A;  4B6I A;  1CGO A;  1CPQ A;  2Q9A A;  4J7T A;  5DVW A;  5E3A A;  3FDQ A;  3I5P A;  3UGO A;  2YEV A;  1ZHZ A;  2J0W A;  3ZQV A;  4BEM J;  4XPY A;  2NSF A;  3M15 A;  4IGG A;  1LKX A;  3M79 A;  4XEV A;  4YJW A;  5CIV A;  1VTM P;  4YWQ A;  1HW1 A;  3CSK A;  4MVZ A;  3CZ6 A; 
#chains in the Genus database with same CATH homology
 2L7A A;  2X0C A;  5L0J A;  1H6G A;  1RKE A;  1DOW A;  2B0H A;  1ZW2 A;  1SYQ A;  3H2U A;  1ST6 A;  5L0F A;  5L0G A;  3TJ6 A;  3TJ5 A;  1YDI A;  4P9T A;  3ZDL A;  4EHP A;  4ONS A;  5L0D A;  3MYI A;  2HSQ A;  1DOV A;  4W8P A;  3RF3 A;  2GWW A;  1T01 A;  5L0C A;  2GDC A;  3T6G B;  1U89 A;  4K1O A;  1ZVZ A;  1RKE B;  4PR9 A;  5FZT A;  4E18 A;  1XWJ A;  1QKR A;  1TR2 A;  3S90 A;  3VF0 A;  5L0I A;  4E17 A;  3H2V A;  4IGG A;  1ZW3 A;  2LQG A;  1L7C A;  1U6H A;  1RKC A;  2IBF A;  5L0H A;  4DJ9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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