1T2RA

Structural basis for 3' end recognition of nucleic acids by the drosophila argonaute 2 paz domain
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
123
structure length
123
Chain Sequence
GAMAMPMIEYLERFSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIASYFHSRNYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
pubmed doi rcsb
molecule tags Nucleic acid binding protein/rna
source organism Drosophila melanogaster
molecule keywords 5'-R(*CP*UP*CP*AP*C)-3'
total genus 26
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2004-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 1t2rA00
4Z4IA 3O7XA 3QIRA 3O6EX 1T2SA 4Z4HA 1SI2A 4OLBA 4W5TA 1VYNA 4Z4CA 4W5NA 4NGGA 5KI6A 4OLAA 4NGCA 5JS1A 4Z4EA 2XFMA 4NH5A 2FFLA 5T7BA 2L5DA 2QVWA 4NGDA 2L5CA 3O3IX 3MJ0A 1T2RA 4NHAA 4KRFA 1SI3A 4W5RA 4Z4GA 4NH3A 4F3TA 1R6ZA 4NGFA 1R4KA 4NH6A 4KREA 4W5QA 4Z4FA 4W5OA 5JS2A 3O7VX 4NGBA
chains in the Genus database with same CATH superfamily
4Z4IA 3O7XA 3QIRA 3O6EX 1T2SA 2DB9A 4Z4HA 1SI2A 3U1UA 4OLBA 4W5TA 1VYNA 2BZEA 4Z4CA 1U04A 4W5NA 1Z25A 3HM9A 3HJFA 4NGGA 4L1PA 5KI6A 3HVRA 4NGCA 4OLAA 5JS1A 4Z4EA 2XFMA 3HK2A 4NH5A 2FFLA 5T7BA 2L5DA 4NGBA 2QVWA 4NGDA 2L5CA 3DLBA 3O3IX 3MJ0A 4L1UA 1T2RA 3HO1A 1Z26A 4NHAA 4KRFA 1SI3A 4W5RA 4Z4GA 4NH3A 4F3TA 1R6ZA 4NGFA 1R4KA 4NH6A 4KREA 3F73A 4W5QA 4Z4FA 4W5OA 3DA5A 5JS2A 3O7VX 3DLHA
chains in the Genus database with same CATH topology
4Z4IA 3O7XA 3QIRA 3O6EX 1T2SA 2DB9A 4Z4HA 1SI2A 3U1UA 4OLBA 4W5TA 1VYNA 2BZEA 4Z4CA 1U04A 4W5NA 1Z25A 3HM9A 3HJFA 4NGGA 4L1PA 5KI6A 3HVRA 4NGCA 4OLAA 5JS1A 4Z4EA 2XFMA 3HK2A 4NH5A 2FFLA 5T7BA 2L5DA 4NGBA 2QVWA 4NGDA 2L5CA 3DLBA 3O3IX 3MJ0A 4L1UA 1T2RA 3HO1A 1Z26A 4NHAA 4KRFA 1SI3A 4W5RA 4Z4GA 4NH3A 4F3TA 1R6ZA 4NGFA 1R4KA 4NH6A 4KREA 3F73A 4W5QA 4Z4FA 4W5OA 3DA5A 5JS2A 3O7VX 3DLHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z4I A;  3O7X A;  3QIR A;  3O6E X;  1T2S A;  4Z4H A;  1SI2 A;  4OLB A;  4W5T A;  1VYN A;  4Z4C A;  4W5N A;  4NGG A;  5KI6 A;  4OLA A;  4NGC A;  5JS1 A;  4Z4E A;  2XFM A;  4NH5 A;  2FFL A;  5T7B A;  2L5D A;  2QVW A;  4NGD A;  2L5C A;  3O3I X;  3MJ0 A;  1T2R A;  4NHA A;  4KRF A;  1SI3 A;  4W5R A;  4Z4G A;  4NH3 A;  4F3T A;  1R6Z A;  4NGF A;  1R4K A;  4NH6 A;  4KRE A;  4W5Q A;  4Z4F A;  4W5O A;  5JS2 A;  3O7V X;  4NGB A; 
#chains in the Genus database with same CATH topology
 4Z4I A;  3O7X A;  3QIR A;  3O6E X;  1T2S A;  2DB9 A;  4Z4H A;  1SI2 A;  3U1U A;  4OLB A;  4W5T A;  1VYN A;  2BZE A;  4Z4C A;  1U04 A;  4W5N A;  1Z25 A;  3HM9 A;  3HJF A;  4NGG A;  4L1P A;  5KI6 A;  3HVR A;  4NGC A;  4OLA A;  5JS1 A;  4Z4E A;  2XFM A;  3HK2 A;  4NH5 A;  2FFL A;  5T7B A;  2L5D A;  4NGB A;  2QVW A;  4NGD A;  2L5C A;  3DLB A;  3O3I X;  3MJ0 A;  4L1U A;  1T2R A;  3HO1 A;  1Z26 A;  4NHA A;  4KRF A;  1SI3 A;  4W5R A;  4Z4G A;  4NH3 A;  4F3T A;  1R6Z A;  4NGF A;  1R4K A;  4NH6 A;  4KRE A;  3F73 A;  4W5Q A;  4Z4F A;  4W5O A;  3DA5 A;  5JS2 A;  3O7V X;  3DLH A; 
#chains in the Genus database with same CATH homology
 4Z4I A;  3O7X A;  3QIR A;  3O6E X;  1T2S A;  2DB9 A;  4Z4H A;  1SI2 A;  3U1U A;  4OLB A;  4W5T A;  1VYN A;  2BZE A;  4Z4C A;  1U04 A;  4W5N A;  1Z25 A;  3HM9 A;  3HJF A;  4NGG A;  4L1P A;  5KI6 A;  3HVR A;  4NGC A;  4OLA A;  5JS1 A;  4Z4E A;  2XFM A;  3HK2 A;  4NH5 A;  2FFL A;  5T7B A;  2L5D A;  4NGB A;  2QVW A;  4NGD A;  2L5C A;  3DLB A;  3O3I X;  3MJ0 A;  4L1U A;  1T2R A;  3HO1 A;  1Z26 A;  4NHA A;  4KRF A;  1SI3 A;  4W5R A;  4Z4G A;  4NH3 A;  4F3T A;  1R6Z A;  4NGF A;  1R4K A;  4NH6 A;  4KRE A;  3F73 A;  4W5Q A;  4Z4F A;  4W5O A;  3DA5 A;  5JS2 A;  3O7V X;  3DLH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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