1T7QA

Crystal structure of the f565a mutant of murine carnitine acetyltransferase in complex with carnitine and coa
Total Genus 220
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
220
sequence length
599
structure length
599
Chain Sequence
SHMAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMAFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase
pubmed doi rcsb
molecule keywords Carnitine acetyltransferase
molecule tags Transferase
source organism Mus musculus
total genus 220
structure length 599
sequence length 599
chains with identical sequence B
ec nomenclature ec 2.3.1.7: Carnitine O-acetyltransferase.
pdb deposition date 2004-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00755 Carn_acyltransf Choline/Carnitine o-acyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.40 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1t7qA01
3.30.559.70 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1t7qA02
1NDBA 4EPHA 2H3UA 1T1UA 2DEBA 4EP9A 2H4TA 1S5OA 1T7OA 4EYWA 2FY3A 1Q6XA 1T7QA 1NDIA 1NM8A 2FYOA 1NDFA 2FW3A 2H3PA 2FY5A 1T7NA 2FY4A 2FY2A 2H3WA 2RCUA
chains in the Genus database with same CATH superfamily
4EPHA 2E1VA 4EP9A 3MAEA 1NOCB 1T7QA 1NDIA 2FYOA 1Q23A 2XR7A 1CLAA 1EADA 3FP0A 1EACA 2RKVA 1T7NA 1EABA 1NDBA 1XMCA 2H3UA 1T1UA 5DU9A 4G22A 1XL7A 2H4TA 4KE4A 4EYWA 2II5A 1QCAA 3B30A 4KECA 1Q6XA 1NM8A 1NDFA 2FW3A 2H3PA 1E2OA 5DUAA 3U9FA 1CIAA 1EAAA 2E1TA 2II3A 2E1UA 3U9BA 4JN5A 2DEBA 1S5OA 2XHGA 4N72A 2FY3A 4G2MA 1XL8A 1EAFA 2RKTA 3FOTA 2BGHA 5KJVA 5T3EA 5KJUA 3B2SA 1PD5A 2FY2A 1L5AA 2RCUA 2JGPA 1XMDA 2CLAA 1DPDA 3CLAA 1Q9JA 2VSQA 1SCZA 1T7OA 1DPCA 2ZBAA 5KJWA 4G0BA 2IHWA 4CLAA 2FY5A 1DPBA 3L60A 2II4A 2FY4A 1EAEA 5FANA 4HVMA 5KJSA 1C4TA 5FALA 5KJTA 2I9DA 2H3WA 4JN3A
chains in the Genus database with same CATH topology
1NDBA 4EPHA 2JGPA 4JN5A 2H3UA 1T1UA 5DU9A 2DEBA 4EP9A 1Q9JA 2VSQA 2H4TA 1S5OA 1T7OA 2XHGA 4EYWA 2FY3A 1Q6XA 1T7QA 1NDIA 1NM8A 2FYOA 3FOTA 3FP0A 1NDFA 2FW3A 2H3PA 5T3EA 2FY5A 5DUAA 1T7NA 2FY4A 4HVMA 2FY2A 1L5AA 2H3WA 4JN3A 2RCUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NDB A;  4EPH A;  2H3U A;  1T1U A;  2DEB A;  4EP9 A;  2H4T A;  1S5O A;  1T7O A;  4EYW A;  2FY3 A;  1Q6X A;  1T7Q A;  1NDI A;  1NM8 A;  2FYO A;  1NDF A;  2FW3 A;  2H3P A;  2FY5 A;  1T7N A;  2FY4 A;  2FY2 A;  2H3W A;  2RCU A; 
#chains in the Genus database with same CATH topology
 4EPH A;  2E1V A;  4EP9 A;  3MAE A;  1NOC B;  1T7Q A;  1NDI A;  2FYO A;  1Q23 A;  2XR7 A;  1CLA A;  1EAD A;  3FP0 A;  1EAC A;  2RKV A;  1T7N A;  1EAB A;  1NDB A;  1XMC A;  2H3U A;  1T1U A;  5DU9 A;  4G22 A;  1XL7 A;  2H4T A;  4KE4 A;  4EYW A;  2II5 A;  1QCA A;  3B30 A;  4KEC A;  1Q6X A;  1NM8 A;  1NDF A;  2FW3 A;  2H3P A;  1E2O A;  5DUA A;  3U9F A;  1CIA A;  1EAA A;  2E1T A;  2II3 A;  2E1U A;  3U9B A;  4JN5 A;  2DEB A;  1S5O A;  2XHG A;  4N72 A;  2FY3 A;  4G2M A;  1XL8 A;  1EAF A;  2RKT A;  3FOT A;  2BGH A;  5KJV A;  5T3E A;  5KJU A;  3B2S A;  1PD5 A;  2FY2 A;  1L5A A;  2RCU A;  2JGP A;  1XMD A;  2CLA A;  1DPD A;  3CLA A;  1Q9J A;  2VSQ A;  1SCZ A;  1T7O A;  1DPC A;  2ZBA A;  5KJW A;  4G0B A;  2IHW A;  4CLA A;  2FY5 A;  1DPB A;  3L60 A;  2II4 A;  2FY4 A;  1EAE A;  5FAN A;  4HVM A;  5KJS A;  1C4T A;  5FAL A;  5KJT A;  2I9D A;  2H3W A;  4JN3 A; 
#chains in the Genus database with same CATH homology
 1NDB A;  4EPH A;  2JGP A;  4JN5 A;  2H3U A;  1T1U A;  5DU9 A;  2DEB A;  4EP9 A;  1Q9J A;  2VSQ A;  2H4T A;  1S5O A;  1T7O A;  2XHG A;  4EYW A;  2FY3 A;  1Q6X A;  1T7Q A;  1NDI A;  1NM8 A;  2FYO A;  3FOT A;  3FP0 A;  1NDF A;  2FW3 A;  2H3P A;  5T3E A;  2FY5 A;  5DUA A;  1T7N A;  2FY4 A;  4HVM A;  2FY2 A;  1L5A A;  2H3W A;  4JN3 A;  2RCU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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