1T9GA

Structure of the human mcad:etf complex
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
386
structure length
386
Chain Sequence
LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Extensive domain motion and electron transfer in the human electron transferring flavoprotein-medium chain Acyl-CoA dehydrogenase complex
pubmed doi rcsb
molecule tags Oxidoreductase, electron transport
source organism Homo sapiens
molecule keywords Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial
total genus 141
structure length 386
sequence length 386
chains with identical sequence B, C, D
ec nomenclature ec 1.3.8.7: Medium-chain acyl-CoA dehydrogenase.
pdb deposition date 2004-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 1t9gA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 1t9gA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 1t9gA02
2YYJA 4Q17A 3AFEA 4KCFA 1FS7A 1SIRA 2IX6A 3LGQA 2CX9A 5K3JA 3D9DA 3MXLA 2JBTA 3UBRA 4ZYJA 4O5MA 2YYLA 4OO2A 4W9UA 4RM7A 1JQIA 2VR0A 2YYGA 2ZO5A 3OIBA 3D9EA 3D9FA 2J7AA 2FONA 3X0XA 1OAHA 2YYMA 2EBAA 2C12A 4G5EA 2REHA 3B96A 4U83A 3MKHA 1FS8A 4WJYA 3D9GA 4L3YA 2A1TA 4N5FA 3MMOA 4Q5BA 2RDZA 2RF7A 2PG0A 1IVHA 3II9A 2C0UA 3M9VA 3SWOA 1W07A 4X28A 3BNGA 3AFFA 3TORA 3MDDA 1R2JA 1WS9A 2YYKA 3GNCA 4Q0TA 3S7WA 3EONA 2JBSA 3D6BA 3BNFA 4XVXA 3MDEA 2E80A 3BNHA 3EOMA 1UKWA 2JIFA 4M9AA 3OWAA 2E81A 3GQTA 2OR0A 4KTOA 4DOYA 2DVLA 3MPIA 1EGCA 4Q1OA 3TTBA 2DDHA 4P13A 2OT4A 4ZXVA 3R7KA 4L1FA 1U8VA 3SXQA 1IS2A 1EGEA 4IRNA 1SIQA 4L3XA 4IV6A 3OWMA 1GU6A 2VIGA 2RFQA 3MPJA 5K3GA 4Q4UA 3UU9A 1T9GA 2WBIA 3NF4A 2ZAFA 4X28C 5K3IA 4JEKA 4HR3A 3FO3A 3GM6A 2UXWA 4NXLA 2YYIA 4L3ZA 5K3HA 2JBRA 1RX0A 2R0MA 3PFDA 2R0NA 1BUCA 3L1TA 3P4TA 2IX5A 1QDBA 3D1IA 3FCJA 4L38A 3RKHA 3HWCA 3SCEA 3X0YA 1UDYA 3BNJA 3SF6A 3F29A 1EGDA 2Z1QA 3LG1A 1FS9A 4Q5CA 2D29A
chains in the Genus database with same CATH superfamily
2YYJA 4Q17A 2R03A 3AFEA 4P79A 4KCFA 1FS7A 1SIRA 2IX6A 2EC5A 1GKZA 1Y8OA 2BU5A 2OEXA 3Q22A 3LGQA 2CX9A 5K3JA 4QICA 4FF4A 3D9DA 3MXLA 2JBTA 3UBRA 4MPEA 4ZYJA 3Q24A 4O5MA 2CJ6A 2YYLA 4LQQB 4OO2A 4W9UA 1GJVA 4RM7A 1JQIA 1XFUA 4FZ4A 4E01A 2VR0A 2YYGA 2ZO5A 3OIBA 3D9EA 3D9FA 2J7AA 2OJQA 2ZKJA 3C2PA 2FONA 3X0XA 1OAHA 2YYMA 3CE2A 4MPCA 2HJNA 3Q23A 2EBAA 3CRLA 2ZDYA 1PK0A 2C12A 3CRKA 4G5EA 2REHA 3B96A 4E00A 5B5WA 4U83A 3N0RA 2YGWA 3MKHA 1FS8A 1XFXA 4WJYA 3X29A 1PI1A 4E02A 2Q8IA 3D9GA 4L3YA 2A1TA 1XFVA 4N5FA 5B5VA 3TZ4A 2Q8FA 3MMOA 4Q5BA 4FF1A 2BU8A 2RDZA 1K93A 4F0XA 2RF7A 2BU6A 2PG0A 1X90A 1IVHA 3II9A 2QR4A 2C0UA 4FF2A 5EZ3A 3M9VA 1JM6A 3SWOA 5GJVE 4AKHA 1W07A 4X28A 3BNGA 3AFFA 3TORA 3MDDA 2XQRB 2Q8GA 3VADA 1R2JA 1WS9A 2YYKA 3GNCA 1Y0VA 4Q0TA 3EONA 1RP3A 1XFZA 1Y8PA 2R05A 2JBSA 4KSAA 5BRKA 3D6BA 2OEVA 4XVXA 3MDEA 2E80A 3BNFA 4MPNA 3BNHA 3EOMA 1UKWA 2JIFA 4M9AA 3OWAA 1X91A 4HKRA 4MP2A 3U33A 1R3BA 2E81A 3GQTA 1K90A 1GKXA 1X8ZA 2OR0A 2PNRA 4KTOA 2XS1A 4DOYA 1RJ4A 2DVLA 3MPIA 4J1VA 1EGCA 4AKGA 2AZEA 2GBBA 4Q1OA 2FP2A 5M4KA 3TTBA 4LQSB 2DDHA 5M4MA 2CJ5A 2PO4A 3S7WA 4P13A 2R02A 2OT4A 4ZXVA 3R7KA 4L1FA 4HKSA 1U8VA 4H7QA 3DJLA 2Q8HA 4AI6A 3SXQA 1IS2A 1EGEA 3TZ5A 4KS9A 4IRNA 1SIQA 4G97A 4L3XA 2CJ7A 4IV6A 3VKGA 3OWMA 1GU6A 2FP1A 3C3LA 2VIGA 2RFQA 1Y8NA 2EBHX 4V25A 3MPJA 2CJ4A 2ZDXA 5K3GA 4Q4UA 5BRMA 3UU9A 1T9GA 2WBIA 3Q0AA 3NF4A 2ZAFA 4X28C 5K3IA 4JEKA 4HR3A 1K8TA 3FO3A 5B6BA 5J71A 3GM6A 3C46A 4FF3A 4V26A 2CJ8A 2BU7A 4KSFA 2BTZA 2UXWA 5GJWE 4NXLA 2F6LA 2YYIA 1XG2B 4L3ZA 5K3HA 2JBRA 1RX0A 2R0MA 1SC5A 3D2RA 3KMLA 4MP7A 3PFDA 2R0NA 1BUCA 3TZ2A 3L1TA 4DZYA 4AKIA 3P4TA 2VF1A 2IX5A 1XFYA 1QDBA 3D1IA 3FCJA 2BU2A 2XS8A 4JIOA 4L38A 3RKHA 5J6AA 1LVCA 3HWCA 4JIZA 3VKHA 1SK6A 3SCEA 3X0YA 2E0AA 1UDYA 1XFWA 3SF6A 3BNJA 2EBFX 4H81A 5M4PA 3F29A 1EGDA 2Z1QA 2AO2A 2LFWA 1RJ1A 4H85A 1S26A 3LG1A 1FS9A 4Q5CA 3TZ0A 2D29A 5M4NA
chains in the Genus database with same CATH topology
2YYJA 4Q17A 3AFEA 4KCFA 1FS7A 1SIRA 2IX6A 3LGQA 2CX9A 5K3JA 3D9DA 3MXLA 2JBTA 3UBRA 4ZYJA 4O5MA 2YYLA 4OO2A 4W9UA 4RM7A 1JQIA 2VR0A 2YYGA 2ZO5A 3OIBA 3D9EA 3D9FA 2J7AA 2FONA 3X0XA 1OAHA 2YYMA 2EBAA 2C12A 4G5EA 2REHA 3B96A 4U83A 3MKHA 1FS8A 4WJYA 3D9GA 4L3YA 2A1TA 4N5FA 3MMOA 4Q5BA 2RDZA 2RF7A 2PG0A 1IVHA 3II9A 2C0UA 3M9VA 3SWOA 1W07A 4X28A 3BNGA 3AFFA 3TORA 3MDDA 1R2JA 1WS9A 2YYKA 3GNCA 4Q0TA 3S7WA 3EONA 2JBSA 3D6BA 3BNFA 4XVXA 3MDEA 2E80A 3BNHA 3EOMA 1UKWA 2JIFA 4M9AA 3OWAA 2E81A 3GQTA 2OR0A 4KTOA 4DOYA 2DVLA 3MPIA 1EGCA 4Q1OA 3TTBA 2DDHA 4P13A 2OT4A 4ZXVA 3R7KA 4L1FA 1U8VA 3SXQA 1IS2A 1EGEA 4IRNA 1SIQA 4L3XA 4IV6A 3OWMA 1GU6A 2VIGA 2RFQA 3MPJA 5K3GA 4Q4UA 3UU9A 1T9GA 2WBIA 3NF4A 2ZAFA 4X28C 5K3IA 4JEKA 4HR3A 3FO3A 3GM6A 2UXWA 4NXLA 2YYIA 4L3ZA 5K3HA 2JBRA 1RX0A 2R0MA 3PFDA 2R0NA 1BUCA 3L1TA 3P4TA 2IX5A 1QDBA 3D1IA 3FCJA 4L38A 3RKHA 3HWCA 3SCEA 3X0YA 1UDYA 3BNJA 3SF6A 3F29A 1EGDA 2Z1QA 3LG1A 1FS9A 4Q5CA 2D29A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YYJ A;  4Q17 A;  3AFE A;  4KCF A;  1FS7 A;  1SIR A;  2IX6 A;  3LGQ A;  2CX9 A;  5K3J A;  3D9D A;  3MXL A;  2JBT A;  3UBR A;  4ZYJ A;  4O5M A;  2YYL A;  4OO2 A;  4W9U A;  4RM7 A;  1JQI A;  2VR0 A;  2YYG A;  2ZO5 A;  3OIB A;  3D9E A;  3D9F A;  2J7A A;  2FON A;  3X0X A;  1OAH A;  2YYM A;  2EBA A;  2C12 A;  4G5E A;  2REH A;  3B96 A;  4U83 A;  3MKH A;  1FS8 A;  4WJY A;  3D9G A;  4L3Y A;  2A1T A;  4N5F A;  3MMO A;  4Q5B A;  2RDZ A;  2RF7 A;  2PG0 A;  1IVH A;  3II9 A;  2C0U A;  3M9V A;  3SWO A;  1W07 A;  4X28 A;  3BNG A;  3AFF A;  3TOR A;  3MDD A;  1R2J A;  1WS9 A;  2YYK A;  3GNC A;  4Q0T A;  3S7W A;  3EON A;  2JBS A;  3D6B A;  3BNF A;  4XVX A;  3MDE A;  2E80 A;  3BNH A;  3EOM A;  1UKW A;  2JIF A;  4M9A A;  3OWA A;  2E81 A;  3GQT A;  2OR0 A;  4KTO A;  4DOY A;  2DVL A;  3MPI A;  1EGC A;  4Q1O A;  3TTB A;  2DDH A;  4P13 A;  2OT4 A;  4ZXV A;  3R7K A;  4L1F A;  1U8V A;  3SXQ A;  1IS2 A;  1EGE A;  4IRN A;  1SIQ A;  4L3X A;  4IV6 A;  3OWM A;  1GU6 A;  2VIG A;  2RFQ A;  3MPJ A;  5K3G A;  4Q4U A;  3UU9 A;  1T9G A;  2WBI A;  3NF4 A;  2ZAF A;  4X28 C;  5K3I A;  4JEK A;  4HR3 A;  3FO3 A;  3GM6 A;  2UXW A;  4NXL A;  2YYI A;  4L3Z A;  5K3H A;  2JBR A;  1RX0 A;  2R0M A;  3PFD A;  2R0N A;  1BUC A;  3L1T A;  3P4T A;  2IX5 A;  1QDB A;  3D1I A;  3FCJ A;  4L38 A;  3RKH A;  3HWC A;  3SCE A;  3X0Y A;  1UDY A;  3BNJ A;  3SF6 A;  3F29 A;  1EGD A;  2Z1Q A;  3LG1 A;  1FS9 A;  4Q5C A;  2D29 A; 
#chains in the Genus database with same CATH topology
 2YYJ A;  4Q17 A;  2R03 A;  3AFE A;  4P79 A;  4KCF A;  1FS7 A;  1SIR A;  2IX6 A;  2EC5 A;  1GKZ A;  1Y8O A;  2BU5 A;  2OEX A;  3Q22 A;  3LGQ A;  2CX9 A;  5K3J A;  4QIC A;  4FF4 A;  3D9D A;  3MXL A;  2JBT A;  3UBR A;  4MPE A;  4ZYJ A;  3Q24 A;  4O5M A;  2CJ6 A;  2YYL A;  4LQQ B;  4OO2 A;  4W9U A;  1GJV A;  4RM7 A;  1JQI A;  1XFU A;  4FZ4 A;  4E01 A;  2VR0 A;  2YYG A;  2ZO5 A;  3OIB A;  3D9E A;  3D9F A;  2J7A A;  2OJQ A;  2ZKJ A;  3C2P A;  2FON A;  3X0X A;  1OAH A;  2YYM A;  3CE2 A;  4MPC A;  2HJN A;  3Q23 A;  2EBA A;  3CRL A;  2ZDY A;  1PK0 A;  2C12 A;  3CRK A;  4G5E A;  2REH A;  3B96 A;  4E00 A;  5B5W A;  4U83 A;  3N0R A;  2YGW A;  3MKH A;  1FS8 A;  1XFX A;  4WJY A;  3X29 A;  1PI1 A;  4E02 A;  2Q8I A;  3D9G A;  4L3Y A;  2A1T A;  1XFV A;  4N5F A;  5B5V A;  3TZ4 A;  2Q8F A;  3MMO A;  4Q5B A;  4FF1 A;  2BU8 A;  2RDZ A;  1K93 A;  4F0X A;  2RF7 A;  2BU6 A;  2PG0 A;  1X90 A;  1IVH A;  3II9 A;  2QR4 A;  2C0U A;  4FF2 A;  5EZ3 A;  3M9V A;  1JM6 A;  3SWO A;  5GJV E;  4AKH A;  1W07 A;  4X28 A;  3BNG A;  3AFF A;  3TOR A;  3MDD A;  2XQR B;  2Q8G A;  3VAD A;  1R2J A;  1WS9 A;  2YYK A;  3GNC A;  1Y0V A;  4Q0T A;  3EON A;  1RP3 A;  1XFZ A;  1Y8P A;  2R05 A;  2JBS A;  4KSA A;  5BRK A;  3D6B A;  2OEV A;  4XVX A;  3MDE A;  2E80 A;  3BNF A;  4MPN A;  3BNH A;  3EOM A;  1UKW A;  2JIF A;  4M9A A;  3OWA A;  1X91 A;  4HKR A;  4MP2 A;  3U33 A;  1R3B A;  2E81 A;  3GQT A;  1K90 A;  1GKX A;  1X8Z A;  2OR0 A;  2PNR A;  4KTO A;  2XS1 A;  4DOY A;  1RJ4 A;  2DVL A;  3MPI A;  4J1V A;  1EGC A;  4AKG A;  2AZE A;  2GBB A;  4Q1O A;  2FP2 A;  5M4K A;  3TTB A;  4LQS B;  2DDH A;  5M4M A;  2CJ5 A;  2PO4 A;  3S7W A;  4P13 A;  2R02 A;  2OT4 A;  4ZXV A;  3R7K A;  4L1F A;  4HKS A;  1U8V A;  4H7Q A;  3DJL A;  2Q8H A;  4AI6 A;  3SXQ A;  1IS2 A;  1EGE A;  3TZ5 A;  4KS9 A;  4IRN A;  1SIQ A;  4G97 A;  4L3X A;  2CJ7 A;  4IV6 A;  3VKG A;  3OWM A;  1GU6 A;  2FP1 A;  3C3L A;  2VIG A;  2RFQ A;  1Y8N A;  2EBH X;  4V25 A;  3MPJ A;  2CJ4 A;  2ZDX A;  5K3G A;  4Q4U A;  5BRM A;  3UU9 A;  1T9G A;  2WBI A;  3Q0A A;  3NF4 A;  2ZAF A;  4X28 C;  5K3I A;  4JEK A;  4HR3 A;  1K8T A;  3FO3 A;  5B6B A;  5J71 A;  3GM6 A;  3C46 A;  4FF3 A;  4V26 A;  2CJ8 A;  2BU7 A;  4KSF A;  2BTZ A;  2UXW A;  5GJW E;  4NXL A;  2F6L A;  2YYI A;  1XG2 B;  4L3Z A;  5K3H A;  2JBR A;  1RX0 A;  2R0M A;  1SC5 A;  3D2R A;  3KML A;  4MP7 A;  3PFD A;  2R0N A;  1BUC A;  3TZ2 A;  3L1T A;  4DZY A;  4AKI A;  3P4T A;  2VF1 A;  2IX5 A;  1XFY A;  1QDB A;  3D1I A;  3FCJ A;  2BU2 A;  2XS8 A;  4JIO A;  4L38 A;  3RKH A;  5J6A A;  1LVC A;  3HWC A;  4JIZ A;  3VKH A;  1SK6 A;  3SCE A;  3X0Y A;  2E0A A;  1UDY A;  1XFW A;  3SF6 A;  3BNJ A;  2EBF X;  4H81 A;  5M4P A;  3F29 A;  1EGD A;  2Z1Q A;  2AO2 A;  2LFW A;  1RJ1 A;  4H85 A;  1S26 A;  3LG1 A;  1FS9 A;  4Q5C A;  3TZ0 A;  2D29 A;  5M4N A; 
#chains in the Genus database with same CATH homology
 2YYJ A;  4Q17 A;  3AFE A;  4KCF A;  1FS7 A;  1SIR A;  2IX6 A;  3LGQ A;  2CX9 A;  5K3J A;  3D9D A;  3MXL A;  2JBT A;  3UBR A;  4ZYJ A;  4O5M A;  2YYL A;  4OO2 A;  4W9U A;  4RM7 A;  1JQI A;  2VR0 A;  2YYG A;  2ZO5 A;  3OIB A;  3D9E A;  3D9F A;  2J7A A;  2FON A;  3X0X A;  1OAH A;  2YYM A;  2EBA A;  2C12 A;  4G5E A;  2REH A;  3B96 A;  4U83 A;  3MKH A;  1FS8 A;  4WJY A;  3D9G A;  4L3Y A;  2A1T A;  4N5F A;  3MMO A;  4Q5B A;  2RDZ A;  2RF7 A;  2PG0 A;  1IVH A;  3II9 A;  2C0U A;  3M9V A;  3SWO A;  1W07 A;  4X28 A;  3BNG A;  3AFF A;  3TOR A;  3MDD A;  1R2J A;  1WS9 A;  2YYK A;  3GNC A;  4Q0T A;  3S7W A;  3EON A;  2JBS A;  3D6B A;  3BNF A;  4XVX A;  3MDE A;  2E80 A;  3BNH A;  3EOM A;  1UKW A;  2JIF A;  4M9A A;  3OWA A;  2E81 A;  3GQT A;  2OR0 A;  4KTO A;  4DOY A;  2DVL A;  3MPI A;  1EGC A;  4Q1O A;  3TTB A;  2DDH A;  4P13 A;  2OT4 A;  4ZXV A;  3R7K A;  4L1F A;  1U8V A;  3SXQ A;  1IS2 A;  1EGE A;  4IRN A;  1SIQ A;  4L3X A;  4IV6 A;  3OWM A;  1GU6 A;  2VIG A;  2RFQ A;  3MPJ A;  5K3G A;  4Q4U A;  3UU9 A;  1T9G A;  2WBI A;  3NF4 A;  2ZAF A;  4X28 C;  5K3I A;  4JEK A;  4HR3 A;  3FO3 A;  3GM6 A;  2UXW A;  4NXL A;  2YYI A;  4L3Z A;  5K3H A;  2JBR A;  1RX0 A;  2R0M A;  3PFD A;  2R0N A;  1BUC A;  3L1T A;  3P4T A;  2IX5 A;  1QDB A;  3D1I A;  3FCJ A;  4L38 A;  3RKH A;  3HWC A;  3SCE A;  3X0Y A;  1UDY A;  3BNJ A;  3SF6 A;  3F29 A;  1EGD A;  2Z1Q A;  3LG1 A;  1FS9 A;  4Q5C A;  2D29 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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