1TGXA

X-ray structure at 1.55 a of toxin gamma, a cardiotoxin from naja nigricollis venom. crystal packing reveals a model for insertion into membranes
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
60
structure length
60
Chain Sequence
LKCNQLIPPFWKTCPKGKNLCYKMTMRAAPMVPVKRGCIDVCPKSSLLIKYMCCNTDKCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure at 1.55 A of toxin gamma, a cardiotoxin from Naja nigricollis venom. Crystal packing reveals a model for insertion into membranes.
pubmed doi rcsb
molecule tags Cytotoxin
source organism Naja nigricollis
molecule keywords GAMMA-CARDIOTOXIN
total genus 10
structure length 60
sequence length 60
chains with identical sequence B, C
ec nomenclature
pdb deposition date 1993-11-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00087 Toxin_TOLIP Snake toxin and toxin-like protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1tgxA00
5IMTD 1W6BA 2H8UA 4LFTA 3U74U 1NTXA 2OFSA 1HOYA 2CDXA 2I9BE 1IDIA 3KFDE 3NH7A 2JVEA 3EBXA 2H7ZB 4QTIU 1CDQA 3HH7A 1BXPA 2LCRA 1KBAA 1VB0A 1XT3A 1FSSB 1ONJA 1ZADA 3VTSA 1YWHA 2FD6U 2MJ0A 2CRTA 1ES7B 1CXNA 2MFAA 2LA1A 2QJAC 4ZQYA 1LX5B 1REWC 1KU6B 1TXBA 3NDSA 1IKCA 1JBDA 1S4YA 1NXBA 1I02A 1LJZA 4AEAA 3BT1U 1QKEA 1KFHA 2H7ZA 1RL5A 5DU1A 1FSCA 2H5FA 1KXIA 1NYUA 1KS6A 2UWRA 1TFSA 1ERAA 2QJBC 1IQ9A 1DRSA 2QJ9C 4DO8A 2HLQA 1ERGA 3NEQA 1G6MA 3PLCA 1L4WA 1CDRA 1TXAA 2L03A 1CVOA 2N99A 1JGKA 1HAAA 2BHIA 1M9ZA 2ERAA 2MUOA 4XJJA 1HAJA 1QM7A 1FFJA 1NYSA 1MAHF 5IMYC 2L5SA 1NTNA 1F94A 3KFDI 1ABTA 1IDHA 1FRAA 2BTXA 2GOOB 1IDGA 1NEAA 2MHYA 1H0JA 2CTXA 1CREA 5DO6A 1CDTA 3QB4B 1LXGA 1BTEA 2H64B 3EVSC 4BDTB 4OM5A 2QC1A 1FF4A 1B41B 2H64C 2MJ4A 4P7UA 1HC9B 3U73U 4HQPF 2PJYB 1V6PA 2UX2A 2ABXA 2VLWA 2H62D 5EBXA 1F8UB 2HLRA 4FAOE 1IK8A 4RUDA 2CRSA 1KTZB 4IYEA 1PLOA 2CCXA 2JQPA 3ERAA 4UY2C 3BT2U 1KBTA 3FEVA 1CHVS 1LSIA 1COEA 2X8BB 4BIKB 4EY8B 1CDSA 1LXHA 1IDLA 2GOOC 1HC9A 1CB9A 2NBTA 1JE9A 1MR6A 1TGXA 1CODA 2MJYA 2K3GA 1QKDA 1CCQA 1CXOA 1CTXA 1FASA 1UG4A 4FAOC 1KC4A 2PJYC 5DZ5A 1KL8A 6EBXA 2H62C 1KBSA 4OM4A 2J8BA 1CRFA 3LAQU 1RGJA 1IJCA 1NORA 2MUPA
chains in the Genus database with same CATH superfamily
5IMTD 1W6BA 2H8UA 4LFTA 3U74U 1NTXA 2OFSA 1HOYA 2CDXA 2I9BE 1IDIA 3KFDE 3NH7A 2JVEA 3EBXA 2H7ZB 4QTIU 1CDQA 3HH7A 1BXPA 2LCRA 1KBAA 1VB0A 1XT3A 1FSSB 1ONJA 1ZADA 3VTSA 1YWHA 2FD6U 2MJ0A 2CRTA 1ES7B 1CXNA 2MFAA 2LA1A 2QJAC 4ZQYA 1LX5B 1REWC 1KU6B 1TXBA 3NDSA 1IKCA 1JBDA 1S4YA 1NXBA 1I02A 1LJZA 4AEAA 3BT1U 1QKEA 1KFHA 2H7ZA 1RL5A 5DU1A 1FSCA 2H5FA 1KXIA 1NYUA 1KS6A 2UWRA 1TFSA 1ERAA 2QJBC 1IQ9A 1DRSA 2QJ9C 4DO8A 2HLQA 1ERGA 3NEQA 1G6MA 3PLCA 1L4WA 1CDRA 1TXAA 2L03A 1CVOA 2N99A 1JGKA 1HAAA 2BHIA 1M9ZA 2ERAA 2MUOA 4XJJA 1HAJA 1QM7A 1FFJA 1NYSA 1MAHF 5IMYC 2L5SA 1NTNA 1F94A 3KFDI 1ABTA 1IDHA 1FRAA 2BTXA 2GOOB 1IDGA 1NEAA 2MHYA 1H0JA 2CTXA 1CREA 5DO6A 1CDTA 3QB4B 4KSNA 1LXGA 1BTEA 2H64B 3EVSC 4BDTB 4OM5A 2QC1A 1FF4A 1B41B 2H64C 2MJ4A 4P7UA 1HC9B 3U73U 4HQPF 2PJYB 1V6PA 2UX2A 2ABXA 2VLWA 2H62D 5EBXA 1F8UB 2HLRA 4FAOE 1IK8A 4RUDA 2CRSA 1KTZB 4IYEA 1PLOA 2CCXA 2JQPA 3ERAA 4UY2C 3BT2U 1KBTA 3FEVA 1CHVS 1LSIA 1COEA 2X8BB 4BIKB 4EY8B 1CDSA 1LXHA 1IDLA 2GOOC 1HC9A 1CB9A 2NBTA 1JE9A 1MR6A 1TGXA 1CODA 2MJYA 2K3GA 1QKDA 1CCQA 1CXOA 1CTXA 1FASA 1UG4A 4FAOC 1KC4A 2PJYC 5DZ5A 1KL8A 6EBXA 2H62C 1KBSA 4OM4A 2J8BA 1CRFA 3LAQU 1RGJA 1IJCA 1NORA 2MUPA
chains in the Genus database with same CATH topology
5IMTD 1W6BA 2H8UA 4LFTA 3U74U 1NTXA 2OFSA 1HOYA 2CDXA 2I9BE 1IDIA 3KFDE 3NH7A 2JVEA 3EBXA 2H7ZB 4QTIU 1CDQA 3HH7A 1BXPA 2LCRA 1KBAA 1VB0A 1XT3A 1FSSB 1ONJA 1ZADA 3VTSA 1YWHA 2FD6U 2MJ0A 2CRTA 1ES7B 1CXNA 2MFAA 2LA1A 2QJAC 4ZQYA 1LX5B 1REWC 1KU6B 1TXBA 3NDSA 1IKCA 1JBDA 1S4YA 1NXBA 1I02A 1LJZA 4AEAA 3BT1U 1QKEA 1KFHA 2H7ZA 1RL5A 5DU1A 1FSCA 2H5FA 1KXIA 1NYUA 1KS6A 2UWRA 1TFSA 1ERAA 2QJBC 1IQ9A 1DRSA 2QJ9C 4DO8A 2HLQA 1ERGA 3NEQA 1G6MA 3PLCA 1L4WA 1CDRA 1TXAA 2L03A 1CVOA 2N99A 1JGKA 1HAAA 2BHIA 1M9ZA 2ERAA 2MUOA 4XJJA 1HAJA 1QM7A 1FFJA 1NYSA 1MAHF 5IMYC 2L5SA 1NTNA 1F94A 3KFDI 1ABTA 1IDHA 1FRAA 2BTXA 2GOOB 1IDGA 1NEAA 2MHYA 1H0JA 2CTXA 1CREA 5DO6A 1CDTA 3QB4B 4KSNA 1LXGA 1BTEA 2H64B 3EVSC 4BDTB 4OM5A 2QC1A 1FF4A 1B41B 2H64C 2MJ4A 4P7UA 1HC9B 3U73U 4HQPF 2PJYB 1V6PA 2UX2A 2ABXA 2VLWA 2H62D 5EBXA 1F8UB 2HLRA 4FAOE 1IK8A 4RUDA 2CRSA 1KTZB 4IYEA 1PLOA 2CCXA 2JQPA 3ERAA 4UY2C 3BT2U 1KBTA 3FEVA 1CHVS 1LSIA 1COEA 2X8BB 4BIKB 4EY8B 1CDSA 1LXHA 1IDLA 2GOOC 1HC9A 1CB9A 2NBTA 1JE9A 1MR6A 1TGXA 1CODA 2MJYA 2K3GA 1QKDA 1CCQA 1CXOA 1CTXA 1FASA 1UG4A 4FAOC 1KC4A 2PJYC 5DZ5A 1KL8A 6EBXA 2H62C 1KBSA 4OM4A 2J8BA 1CRFA 3LAQU 1RGJA 1IJCA 1NORA 2MUPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IMT D;  1W6B A;  2H8U A;  4LFT A;  3U74 U;  1NTX A;  2OFS A;  1HOY A;  2CDX A;  2I9B E;  1IDI A;  3KFD E;  3NH7 A;  2JVE A;  3EBX A;  2H7Z B;  4QTI U;  1CDQ A;  3HH7 A;  1BXP A;  2LCR A;  1KBA A;  1VB0 A;  1XT3 A;  1FSS B;  1ONJ A;  1ZAD A;  3VTS A;  1YWH A;  2FD6 U;  2MJ0 A;  2CRT A;  1ES7 B;  1CXN A;  2MFA A;  2LA1 A;  2QJA C;  4ZQY A;  1LX5 B;  1REW C;  1KU6 B;  1TXB A;  3NDS A;  1IKC A;  1JBD A;  1S4Y A;  1NXB A;  1I02 A;  1LJZ A;  4AEA A;  3BT1 U;  1QKE A;  1KFH A;  2H7Z A;  1RL5 A;  5DU1 A;  1FSC A;  2H5F A;  1KXI A;  1NYU A;  1KS6 A;  2UWR A;  1TFS A;  1ERA A;  2QJB C;  1IQ9 A;  1DRS A;  2QJ9 C;  4DO8 A;  2HLQ A;  1ERG A;  3NEQ A;  1G6M A;  3PLC A;  1L4W A;  1CDR A;  1TXA A;  2L03 A;  1CVO A;  2N99 A;  1JGK A;  1HAA A;  2BHI A;  1M9Z A;  2ERA A;  2MUO A;  4XJJ A;  1HAJ A;  1QM7 A;  1FFJ A;  1NYS A;  1MAH F;  5IMY C;  2L5S A;  1NTN A;  1F94 A;  3KFD I;  1ABT A;  1IDH A;  1FRA A;  2BTX A;  2GOO B;  1IDG A;  1NEA A;  2MHY A;  1H0J A;  2CTX A;  1CRE A;  5DO6 A;  1CDT A;  3QB4 B;  1LXG A;  1BTE A;  2H64 B;  3EVS C;  4BDT B;  4OM5 A;  2QC1 A;  1FF4 A;  1B41 B;  2H64 C;  2MJ4 A;  4P7U A;  1HC9 B;  3U73 U;  4HQP F;  2PJY B;  1V6P A;  2UX2 A;  2ABX A;  2VLW A;  2H62 D;  5EBX A;  1F8U B;  2HLR A;  4FAO E;  1IK8 A;  4RUD A;  2CRS A;  1KTZ B;  4IYE A;  1PLO A;  2CCX A;  2JQP A;  3ERA A;  4UY2 C;  3BT2 U;  1KBT A;  3FEV A;  1CHV S;  1LSI A;  1COE A;  2X8B B;  4BIK B;  4EY8 B;  1CDS A;  1LXH A;  1IDL A;  2GOO C;  1HC9 A;  1CB9 A;  2NBT A;  1JE9 A;  1MR6 A;  1TGX A;  1COD A;  2MJY A;  2K3G A;  1QKD A;  1CCQ A;  1CXO A;  1CTX A;  1FAS A;  1UG4 A;  4FAO C;  1KC4 A;  2PJY C;  5DZ5 A;  1KL8 A;  6EBX A;  2H62 C;  1KBS A;  4OM4 A;  2J8B A;  1CRF A;  3LAQ U;  1RGJ A;  1IJC A;  1NOR A;  2MUP A; 
#chains in the Genus database with same CATH topology
 5IMT D;  1W6B A;  2H8U A;  4LFT A;  3U74 U;  1NTX A;  2OFS A;  1HOY A;  2CDX A;  2I9B E;  1IDI A;  3KFD E;  3NH7 A;  2JVE A;  3EBX A;  2H7Z B;  4QTI U;  1CDQ A;  3HH7 A;  1BXP A;  2LCR A;  1KBA A;  1VB0 A;  1XT3 A;  1FSS B;  1ONJ A;  1ZAD A;  3VTS A;  1YWH A;  2FD6 U;  2MJ0 A;  2CRT A;  1ES7 B;  1CXN A;  2MFA A;  2LA1 A;  2QJA C;  4ZQY A;  1LX5 B;  1REW C;  1KU6 B;  1TXB A;  3NDS A;  1IKC A;  1JBD A;  1S4Y A;  1NXB A;  1I02 A;  1LJZ A;  4AEA A;  3BT1 U;  1QKE A;  1KFH A;  2H7Z A;  1RL5 A;  5DU1 A;  1FSC A;  2H5F A;  1KXI A;  1NYU A;  1KS6 A;  2UWR A;  1TFS A;  1ERA A;  2QJB C;  1IQ9 A;  1DRS A;  2QJ9 C;  4DO8 A;  2HLQ A;  1ERG A;  3NEQ A;  1G6M A;  3PLC A;  1L4W A;  1CDR A;  1TXA A;  2L03 A;  1CVO A;  2N99 A;  1JGK A;  1HAA A;  2BHI A;  1M9Z A;  2ERA A;  2MUO A;  4XJJ A;  1HAJ A;  1QM7 A;  1FFJ A;  1NYS A;  1MAH F;  5IMY C;  2L5S A;  1NTN A;  1F94 A;  3KFD I;  1ABT A;  1IDH A;  1FRA A;  2BTX A;  2GOO B;  1IDG A;  1NEA A;  2MHY A;  1H0J A;  2CTX A;  1CRE A;  5DO6 A;  1CDT A;  3QB4 B;  4KSN A;  1LXG A;  1BTE A;  2H64 B;  3EVS C;  4BDT B;  4OM5 A;  2QC1 A;  1FF4 A;  1B41 B;  2H64 C;  2MJ4 A;  4P7U A;  1HC9 B;  3U73 U;  4HQP F;  2PJY B;  1V6P A;  2UX2 A;  2ABX A;  2VLW A;  2H62 D;  5EBX A;  1F8U B;  2HLR A;  4FAO E;  1IK8 A;  4RUD A;  2CRS A;  1KTZ B;  4IYE A;  1PLO A;  2CCX A;  2JQP A;  3ERA A;  4UY2 C;  3BT2 U;  1KBT A;  3FEV A;  1CHV S;  1LSI A;  1COE A;  2X8B B;  4BIK B;  4EY8 B;  1CDS A;  1LXH A;  1IDL A;  2GOO C;  1HC9 A;  1CB9 A;  2NBT A;  1JE9 A;  1MR6 A;  1TGX A;  1COD A;  2MJY A;  2K3G A;  1QKD A;  1CCQ A;  1CXO A;  1CTX A;  1FAS A;  1UG4 A;  4FAO C;  1KC4 A;  2PJY C;  5DZ5 A;  1KL8 A;  6EBX A;  2H62 C;  1KBS A;  4OM4 A;  2J8B A;  1CRF A;  3LAQ U;  1RGJ A;  1IJC A;  1NOR A;  2MUP A; 
#chains in the Genus database with same CATH homology
 5IMT D;  1W6B A;  2H8U A;  4LFT A;  3U74 U;  1NTX A;  2OFS A;  1HOY A;  2CDX A;  2I9B E;  1IDI A;  3KFD E;  3NH7 A;  2JVE A;  3EBX A;  2H7Z B;  4QTI U;  1CDQ A;  3HH7 A;  1BXP A;  2LCR A;  1KBA A;  1VB0 A;  1XT3 A;  1FSS B;  1ONJ A;  1ZAD A;  3VTS A;  1YWH A;  2FD6 U;  2MJ0 A;  2CRT A;  1ES7 B;  1CXN A;  2MFA A;  2LA1 A;  2QJA C;  4ZQY A;  1LX5 B;  1REW C;  1KU6 B;  1TXB A;  3NDS A;  1IKC A;  1JBD A;  1S4Y A;  1NXB A;  1I02 A;  1LJZ A;  4AEA A;  3BT1 U;  1QKE A;  1KFH A;  2H7Z A;  1RL5 A;  5DU1 A;  1FSC A;  2H5F A;  1KXI A;  1NYU A;  1KS6 A;  2UWR A;  1TFS A;  1ERA A;  2QJB C;  1IQ9 A;  1DRS A;  2QJ9 C;  4DO8 A;  2HLQ A;  1ERG A;  3NEQ A;  1G6M A;  3PLC A;  1L4W A;  1CDR A;  1TXA A;  2L03 A;  1CVO A;  2N99 A;  1JGK A;  1HAA A;  2BHI A;  1M9Z A;  2ERA A;  2MUO A;  4XJJ A;  1HAJ A;  1QM7 A;  1FFJ A;  1NYS A;  1MAH F;  5IMY C;  2L5S A;  1NTN A;  1F94 A;  3KFD I;  1ABT A;  1IDH A;  1FRA A;  2BTX A;  2GOO B;  1IDG A;  1NEA A;  2MHY A;  1H0J A;  2CTX A;  1CRE A;  5DO6 A;  1CDT A;  3QB4 B;  4KSN A;  1LXG A;  1BTE A;  2H64 B;  3EVS C;  4BDT B;  4OM5 A;  2QC1 A;  1FF4 A;  1B41 B;  2H64 C;  2MJ4 A;  4P7U A;  1HC9 B;  3U73 U;  4HQP F;  2PJY B;  1V6P A;  2UX2 A;  2ABX A;  2VLW A;  2H62 D;  5EBX A;  1F8U B;  2HLR A;  4FAO E;  1IK8 A;  4RUD A;  2CRS A;  1KTZ B;  4IYE A;  1PLO A;  2CCX A;  2JQP A;  3ERA A;  4UY2 C;  3BT2 U;  1KBT A;  3FEV A;  1CHV S;  1LSI A;  1COE A;  2X8B B;  4BIK B;  4EY8 B;  1CDS A;  1LXH A;  1IDL A;  2GOO C;  1HC9 A;  1CB9 A;  2NBT A;  1JE9 A;  1MR6 A;  1TGX A;  1COD A;  2MJY A;  2K3G A;  1QKD A;  1CCQ A;  1CXO A;  1CTX A;  1FAS A;  1UG4 A;  4FAO C;  1KC4 A;  2PJY C;  5DZ5 A;  1KL8 A;  6EBX A;  2H62 C;  1KBS A;  4OM4 A;  2J8B A;  1CRF A;  3LAQ U;  1RGJ A;  1IJC A;  1NOR A;  2MUP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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