1TKSA

Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of candida albicans
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
202
structure length
196
Chain Sequence
NIFTPIEEALEAYKNGEFLIVMDDEDRENEGDLIMAAELITQEKMAFLVRYSSGYVCVPLSEERANQLELPPMLAGTAYTITCDFAEGTTTGISAHDRALTTRSLANPNSKPQDFIKPGHILPLRAVPGLLKKRRGHTEAAVQLSTLAGLQPAGVICELVRDEDGLMMRLDDCIQFGKKHGIKIININQLVEYISK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords 3,4-dihydroxy-2-butanone 4-phosphate synthase
publication title Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans.
pubmed doi rcsb
source organism Candida albicans
total genus 64
structure length 196
sequence length 202
chains with identical sequence B
ec nomenclature ec 4.1.99.12: 3,4-dihydroxy-2-butanone-4-phosphate synthase.
pdb deposition date 2004-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 1tksA00
1JCUA 3MK5A 3AJEA 4P8JA 1K4OA 1TKSA 1TKUA 4FFJA 4P6PA 3L7VA 1K4PA 1K4LA 3LQUA 2MX1A 3LRJA 1PVYA 4P8EA 1K7JA 1K4IA 2RIUA 1SNNA 3MIOA 3H07A 4P6DA 2RISA 1IEZA 4E1BA 4P6CA 1HRUA 4P77A 1K49A 3LS6A 1G58A 1PVWA 3MGZA 4I14A 1G57A 2EQAA 1KK9A
chains in the Genus database with same CATH superfamily
1JCUA 3MK5A 3AJEA 4P8JA 1K4OA 1TKSA 3TSPA 1TKUA 4FFJA 3TSQA 3VETA 4P6PA 3VEWA 3L7VA 1K4PA 3VEXA 1K4LA 3LQUA 2MX1A 3LRJA 3TSUA 3TTDA 1PVYA 3VEOA 4P8EA 3VF4A 3VEZA 1K7JA 1K4IA 3VERA 2RIUA 1SNNA 3MIOA 3TTFA 3H07A 4P6DA 3VF2A 2RISA 3VTHA 1IEZA 4E1BA 3VENA 3TTCA 4P6CA 1HRUA 4P77A 1K49A 3LS6A 3VESA 1G58A 1PVWA 3MGZA 4I14A 3VTIA 1G57A 2EQAA 1KK9A
chains in the Genus database with same CATH topology
1JCUA 3MK5A 3AJEA 4P8JA 1K4OA 1TKSA 3TSPA 1TKUA 4FFJA 3TSQA 3VETA 4P6PA 3VEWA 3L7VA 1K4PA 3VEXA 1K4LA 3LQUA 2MX1A 3LRJA 3TSUA 3TTDA 1PVYA 3VEOA 4P8EA 3VF4A 3VEZA 1K7JA 1K4IA 3VERA 2RIUA 1SNNA 3MIOA 3TTFA 3H07A 4P6DA 3VF2A 2RISA 3VTHA 1IEZA 4E1BA 3VENA 3TTCA 4P6CA 1HRUA 4P77A 1K49A 3LS6A 3VESA 1G58A 1PVWA 3MGZA 4I14A 3VTIA 1G57A 2EQAA 1KK9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JCU A;  3MK5 A;  3AJE A;  4P8J A;  1K4O A;  1TKS A;  1TKU A;  4FFJ A;  4P6P A;  3L7V A;  1K4P A;  1K4L A;  3LQU A;  2MX1 A;  3LRJ A;  1PVY A;  4P8E A;  1K7J A;  1K4I A;  2RIU A;  1SNN A;  3MIO A;  3H07 A;  4P6D A;  2RIS A;  1IEZ A;  4E1B A;  4P6C A;  1HRU A;  4P77 A;  1K49 A;  3LS6 A;  1G58 A;  1PVW A;  3MGZ A;  4I14 A;  1G57 A;  2EQA A;  1KK9 A; 
#chains in the Genus database with same CATH topology
 1JCU A;  3MK5 A;  3AJE A;  4P8J A;  1K4O A;  1TKS A;  3TSP A;  1TKU A;  4FFJ A;  3TSQ A;  3VET A;  4P6P A;  3VEW A;  3L7V A;  1K4P A;  3VEX A;  1K4L A;  3LQU A;  2MX1 A;  3LRJ A;  3TSU A;  3TTD A;  1PVY A;  3VEO A;  4P8E A;  3VF4 A;  3VEZ A;  1K7J A;  1K4I A;  3VER A;  2RIU A;  1SNN A;  3MIO A;  3TTF A;  3H07 A;  4P6D A;  3VF2 A;  2RIS A;  3VTH A;  1IEZ A;  4E1B A;  3VEN A;  3TTC A;  4P6C A;  1HRU A;  4P77 A;  1K49 A;  3LS6 A;  3VES A;  1G58 A;  1PVW A;  3MGZ A;  4I14 A;  3VTI A;  1G57 A;  2EQA A;  1KK9 A; 
#chains in the Genus database with same CATH homology
 1JCU A;  3MK5 A;  3AJE A;  4P8J A;  1K4O A;  1TKS A;  3TSP A;  1TKU A;  4FFJ A;  3TSQ A;  3VET A;  4P6P A;  3VEW A;  3L7V A;  1K4P A;  3VEX A;  1K4L A;  3LQU A;  2MX1 A;  3LRJ A;  3TSU A;  3TTD A;  1PVY A;  3VEO A;  4P8E A;  3VF4 A;  3VEZ A;  1K7J A;  1K4I A;  3VER A;  2RIU A;  1SNN A;  3MIO A;  3TTF A;  3H07 A;  4P6D A;  3VF2 A;  2RIS A;  3VTH A;  1IEZ A;  4E1B A;  3VEN A;  3TTC A;  4P6C A;  1HRU A;  4P77 A;  1K49 A;  3LS6 A;  3VES A;  1G58 A;  1PVW A;  3MGZ A;  4I14 A;  3VTI A;  1G57 A;  2EQA A;  1KK9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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