1TKUA

Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of candida albicans in complex with ribulose-5-phosphate
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
202
structure length
196
Chain Sequence
NIFTPIEEALEAYKNGEFLIVMDDEDRENEGDLIMAAELITQEKMAFLVRYSSGYVCVPLSEERANQLELPPMLAGTAYTITCDFAEGTTTGISAHDRALTTRSLANPNSKPQDFIKPGHILPLRAVPGLLKKRRGHTEAAVQLSTLAGLQPAGVICELVRDEDGLMMRLDDCIQFGKKHGIKIININQLVEYISK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords 3,4-Dihydroxy-2-butanone 4-phosphate Synthase
publication title Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans.
pubmed doi rcsb
source organism Candida albicans
total genus 64
structure length 196
sequence length 202
chains with identical sequence B
ec nomenclature ec 4.1.99.12: 3,4-dihydroxy-2-butanone-4-phosphate synthase.
pdb deposition date 2004-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 1tkuA00
3L7VA 3MGZA 1TKSA 1K4IA 4FFJA 1K7JA 1PVWA 4P6PA 3LS6A 4P6CA 4P6DA 3MIOA 4P8EA 1TKUA 1KK9A 1G58A 1K4OA 1K49A 2RISA 3LRJA 1K4LA 3MK5A 2RIUA 3H07A 3AJEA 4P77A 1PVYA 1G57A 1JCUA 3LQUA 4P8JA 4I14A 1HRUA 2MX1A 1IEZA 4E1BA 1SNNA 1K4PA 2EQAA
chains in the Genus database with same CATH superfamily
3L7VA 3TTDA 3VESA 3MGZA 3VEOA 3VENA 1TKSA 1K4IA 4FFJA 1K7JA 1PVWA 4P6PA 3LS6A 4P6CA 3VF4A 3TTFA 4P6DA 3MIOA 4P8EA 3TTCA 3VERA 1TKUA 1KK9A 1G58A 3VETA 1K4OA 3TSQA 1K49A 2RISA 3LRJA 1K4LA 3VTHA 3MK5A 2RIUA 3H07A 3VEZA 3AJEA 3TSUA 4P77A 1PVYA 1G57A 3VEWA 1JCUA 3LQUA 4P8JA 3TSPA 4I14A 1HRUA 3VTIA 2MX1A 3VEXA 1IEZA 4E1BA 1SNNA 1K4PA 3VF2A 2EQAA
chains in the Genus database with same CATH topology
3L7VA 3TTDA 3VESA 3MGZA 3VEOA 3VENA 1TKSA 1K4IA 4FFJA 1K7JA 1PVWA 4P6PA 3LS6A 4P6CA 3VF4A 3TTFA 4P6DA 3MIOA 4P8EA 3TTCA 3VERA 1TKUA 1KK9A 1G58A 3VETA 1K4OA 3TSQA 1K49A 2RISA 3LRJA 1K4LA 3VTHA 3MK5A 2RIUA 3H07A 3VEZA 3AJEA 3TSUA 4P77A 1PVYA 1G57A 3VEWA 1JCUA 3LQUA 4P8JA 3TSPA 4I14A 1HRUA 3VTIA 2MX1A 3VEXA 1IEZA 4E1BA 1SNNA 1K4PA 3VF2A 2EQAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L7V A;  3MGZ A;  1TKS A;  1K4I A;  4FFJ A;  1K7J A;  1PVW A;  4P6P A;  3LS6 A;  4P6C A;  4P6D A;  3MIO A;  4P8E A;  1TKU A;  1KK9 A;  1G58 A;  1K4O A;  1K49 A;  2RIS A;  3LRJ A;  1K4L A;  3MK5 A;  2RIU A;  3H07 A;  3AJE A;  4P77 A;  1PVY A;  1G57 A;  1JCU A;  3LQU A;  4P8J A;  4I14 A;  1HRU A;  2MX1 A;  1IEZ A;  4E1B A;  1SNN A;  1K4P A;  2EQA A; 
#chains in the Genus database with same CATH topology
 3L7V A;  3TTD A;  3VES A;  3MGZ A;  3VEO A;  3VEN A;  1TKS A;  1K4I A;  4FFJ A;  1K7J A;  1PVW A;  4P6P A;  3LS6 A;  4P6C A;  3VF4 A;  3TTF A;  4P6D A;  3MIO A;  4P8E A;  3TTC A;  3VER A;  1TKU A;  1KK9 A;  1G58 A;  3VET A;  1K4O A;  3TSQ A;  1K49 A;  2RIS A;  3LRJ A;  1K4L A;  3VTH A;  3MK5 A;  2RIU A;  3H07 A;  3VEZ A;  3AJE A;  3TSU A;  4P77 A;  1PVY A;  1G57 A;  3VEW A;  1JCU A;  3LQU A;  4P8J A;  3TSP A;  4I14 A;  1HRU A;  3VTI A;  2MX1 A;  3VEX A;  1IEZ A;  4E1B A;  1SNN A;  1K4P A;  3VF2 A;  2EQA A; 
#chains in the Genus database with same CATH homology
 3L7V A;  3TTD A;  3VES A;  3MGZ A;  3VEO A;  3VEN A;  1TKS A;  1K4I A;  4FFJ A;  1K7J A;  1PVW A;  4P6P A;  3LS6 A;  4P6C A;  3VF4 A;  3TTF A;  4P6D A;  3MIO A;  4P8E A;  3TTC A;  3VER A;  1TKU A;  1KK9 A;  1G58 A;  3VET A;  1K4O A;  3TSQ A;  1K49 A;  2RIS A;  3LRJ A;  1K4L A;  3VTH A;  3MK5 A;  2RIU A;  3H07 A;  3VEZ A;  3AJE A;  3TSU A;  4P77 A;  1PVY A;  1G57 A;  3VEW A;  1JCU A;  3LQU A;  4P8J A;  3TSP A;  4I14 A;  1HRU A;  3VTI A;  2MX1 A;  3VEX A;  1IEZ A;  4E1B A;  1SNN A;  1K4P A;  3VF2 A;  2EQA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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