1TPNA

Solution structure of the fibrin binding finger domain of tissue-type plasminogen activator determined by 1h nuclear magnetic resonance
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
50
structure length
50
Chain Sequence
SYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the fibrin binding finger domain of tissue-type plasminogen activator determined by 1H nuclear magnetic resonance.
pubmed doi rcsb
molecule tags Plasminogen activator
source organism Homo sapiens
molecule keywords TISSUE-TYPE PLASMINOGEN ACTIVATOR
total genus 5
structure length 50
sequence length 50
ec nomenclature ec 3.4.21.68: T-plasminogen activator.
pdb deposition date 1993-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00039 fn1 Fibronectin type I domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1tpnA00
5JPMG 2YBYA 3IX0A 1E5GA 2XRDA 3TVJA 1VVCA 3OP8A 3ZD1A 3ERBA 1QO6A 2A55A 1SS2A 5FO8C 1ELVA 1OK3A 1GHQB 2G7IA 4AYEA 1CKLA 2RKZA 4ONTD 1PPQA 4J38B 4AYMA 3GXEA 2RL0A 1OK1A 1OK9A 4MUCA 2XWBF 5HYTB 1H04P 1HCCA 1TPNA 1ZJKA 3OXUD 1GPZA 3EJHA 2MCYA 2BZMA 4KKDA 2V8EA 2W81A 3L89M 1H2PP 1OJYA 2EC3A 3KXVA 4ZH1D 3MQLA 2IZ4A 2RLPA 1MD7A 3M7PA 1OK2A 3R62A 2QY0A 2MCZA 1O9AA 2KRIA 2IZ3A 3ZD2A 1C1ZA 3IU3I 4B2SA 1GKNA 1Q3XA 3INBC 1E8BA 4FXGG 1H03P 1SRZA 2UWNA 1QUBA 3RJ3D 2XRBA 1MD8A 4PZ5A 4C16A 2CG7A 2LOJA 1H2QP 2ERJA 3O8EB 4AYIA 4WJG2 4CSYA 5HZPB 1OJWA 4B2RA 4A5WB 1U5MA 2CKUA 5I0QB 3SW0X 4IGDA 1GKGA 1E88A 4AYDA 2WIIC 1TPMA 1QGBA 4LOSA 1FBRA 1G4GA 1NWVA 4DJZA 2EHFA 4K12A 3CALA 4JHSA 1Z92B 2XQWC 1OJVA 1HFHA 2JRAA 2O39C 3NFPI 5HYUB 1LY2A 2RKYA 2KMSA 2XWJI 2JGXA 1UOTP 3KZJA 3T5OA 3OEDC 1G4FA 1HFIA 4F4OC 4LOTA 5HYPA 2B5ID 3GOVA 3ZRZA 2CG6A 2YRAA 1VVDA 4YNXA 2RLQA 2JGWA 2W80A 1TPGA
chains in the Genus database with same CATH superfamily
5JPMG 2I2LA 2YBYA 3IX0A 3K3TA 1E5GA 2XRDA 3TVJA 1VVCA 3OP8A 3ZD1A 3WSYA 4MSLA 2X2ZA 3F6KA 3ERBA 1QO6A 2A55A 1SS2A 5FO8C 1ELVA 1OK3A 1GHQB 2G7IA 4AYEA 1CKLA 2RKZA 4ONTD 1PPQA 4J38B 4AYMA 3GXEA 2RL0A 1OK1A 1OK9A 4MUCA 2XWBF 5HYTB 1H04P 1HCCA 1TPNA 3VWOA 3NJAA 1ZJKA 3OXUD 1GPZA 3EJHA 2MCYA 4PO7A 2BZMA 4KKDA 2V8EA 2W81A 3L89M 3FGRA 1H2PP 5DN5A 1OJYA 2EC3A 3KXVA 4ZH1D 3MQLA 5DN4A 2IZ4A 2RLPA 1MD7A 3M7PA 3CI0J 1OK2A 2Y8RA 3R62A 2QY0A 2MCZA 3ZLDA 2Y8TA 1O9AA 2KRIA 2IZ3A 3ZD2A 1C1ZA 3IU3I 4B2SA 1GKNA 1Q3XA 3INBC 1E8BA 4FXGG 1H03P 1SRZA 2UWNA 1QUBA 3RJ3D 2XRBA 1MD8A 4PZ5A 4C16A 2CG7A 2LOJA 2ZYCA 2Y8SA 1H2QP 2ERJA 3O8EB 4AYIA 4WJG2 4YIZA 4CSYA 4BWCA 5HZPB 1OJWA 4B2RA 4A5WB 1U5MA 2CKUA 5I0QB 3SW0X 4IGDA 1GKGA 1E88A 4AYDA 3WSXA 2WIIC 1TPMA 1QGBA 4LOSA 4N7EA 1FBRA 1G4GA 1NWVA 4DJZA 2EHFA 4K12A 3CALA 4JHSA 1Z92B 2XQWC 1OJVA 1HFHA 2JRAA 2O39C 3NFPI 5HYUB 1LY2A 4APLA 2RKYA 3ZLEA 2KMSA 2XWJI 2JGXA 1UOTP 3KZJA 1RLHA 3T5OA 3OEDC 1G4FA 1HFIA 4F4OC 4LOTA 5HYPA 2B5ID 3GOVA 3ZRZA 2CG6A 2YRAA 1VVDA 4YNXA 2RLQA 2JGWA 3FGTA 2W80A 1TPGA
chains in the Genus database with same CATH topology
5JPMG 2YBYA 3IX0A 1E5GA 2XRDA 3TVJA 1VVCA 3OP8A 3ZD1A 3ERBA 1QO6A 2A55A 1SS2A 5FO8C 1ELVA 1OK3A 1GHQB 2G7IA 4AYEA 1CKLA 2RKZA 4ONTD 1PPQA 4J38B 4AYMA 3GXEA 2RL0A 1OK1A 1OK9A 4MUCA 2XWBF 5HYTB 1H04P 1HCCA 1TPNA 1ZJKA 3OXUD 1GPZA 3EJHA 2MCYA 2BZMA 4KKDA 2V8EA 2W81A 3L89M 1H2PP 1OJYA 2EC3A 3KXVA 4ZH1D 3MQLA 2IZ4A 2RLPA 1MD7A 3M7PA 1OK2A 3R62A 2QY0A 2MCZA 1O9AA 2KRIA 2IZ3A 3ZD2A 1C1ZA 3IU3I 4B2SA 1GKNA 1Q3XA 3INBC 1E8BA 4FXGG 1H03P 1SRZA 2UWNA 1QUBA 3RJ3D 2XRBA 1MD8A 4PZ5A 4C16A 2CG7A 2LOJA 1H2QP 2ERJA 3O8EB 4AYIA 4WJG2 4CSYA 5HZPB 1OJWA 4B2RA 4A5WB 1U5MA 2CKUA 5I0QB 3SW0X 4IGDA 1GKGA 1E88A 4AYDA 2WIIC 1TPMA 1QGBA 4LOSA 1FBRA 1G4GA 1NWVA 4DJZA 2EHFA 4K12A 3CALA 4JHSA 1Z92B 2XQWC 1OJVA 1HFHA 2JRAA 2O39C 3NFPI 5HYUB 1LY2A 2RKYA 2KMSA 2XWJI 2JGXA 1UOTP 3KZJA 3T5OA 3OEDC 1G4FA 1HFIA 4F4OC 4LOTA 5HYPA 2B5ID 3GOVA 3ZRZA 2CG6A 2YRAA 1VVDA 4YNXA 2RLQA 2JGWA 2W80A 1TPGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JPM G;  2YBY A;  3IX0 A;  1E5G A;  2XRD A;  3TVJ A;  1VVC A;  3OP8 A;  3ZD1 A;  3ERB A;  1QO6 A;  2A55 A;  1SS2 A;  5FO8 C;  1ELV A;  1OK3 A;  1GHQ B;  2G7I A;  4AYE A;  1CKL A;  2RKZ A;  4ONT D;  1PPQ A;  4J38 B;  4AYM A;  3GXE A;  2RL0 A;  1OK1 A;  1OK9 A;  4MUC A;  2XWB F;  5HYT B;  1H04 P;  1HCC A;  1TPN A;  1ZJK A;  3OXU D;  1GPZ A;  3EJH A;  2MCY A;  2BZM A;  4KKD A;  2V8E A;  2W81 A;  3L89 M;  1H2P P;  1OJY A;  2EC3 A;  3KXV A;  4ZH1 D;  3MQL A;  2IZ4 A;  2RLP A;  1MD7 A;  3M7P A;  1OK2 A;  3R62 A;  2QY0 A;  2MCZ A;  1O9A A;  2KRI A;  2IZ3 A;  3ZD2 A;  1C1Z A;  3IU3 I;  4B2S A;  1GKN A;  1Q3X A;  3INB C;  1E8B A;  4FXG G;  1H03 P;  1SRZ A;  2UWN A;  1QUB A;  3RJ3 D;  2XRB A;  1MD8 A;  4PZ5 A;  4C16 A;  2CG7 A;  2LOJ A;  1H2Q P;  2ERJ A;  3O8E B;  4AYI A;  4WJG 2;  4CSY A;  5HZP B;  1OJW A;  4B2R A;  4A5W B;  1U5M A;  2CKU A;  5I0Q B;  3SW0 X;  4IGD A;  1GKG A;  1E88 A;  4AYD A;  2WII C;  1TPM A;  1QGB A;  4LOS A;  1FBR A;  1G4G A;  1NWV A;  4DJZ A;  2EHF A;  4K12 A;  3CAL A;  4JHS A;  1Z92 B;  2XQW C;  1OJV A;  1HFH A;  2JRA A;  2O39 C;  3NFP I;  5HYU B;  1LY2 A;  2RKY A;  2KMS A;  2XWJ I;  2JGX A;  1UOT P;  3KZJ A;  3T5O A;  3OED C;  1G4F A;  1HFI A;  4F4O C;  4LOT A;  5HYP A;  2B5I D;  3GOV A;  3ZRZ A;  2CG6 A;  2YRA A;  1VVD A;  4YNX A;  2RLQ A;  2JGW A;  2W80 A;  1TPG A; 
#chains in the Genus database with same CATH topology
 5JPM G;  2I2L A;  2YBY A;  3IX0 A;  3K3T A;  1E5G A;  2XRD A;  3TVJ A;  1VVC A;  3OP8 A;  3ZD1 A;  3WSY A;  4MSL A;  2X2Z A;  3F6K A;  3ERB A;  1QO6 A;  2A55 A;  1SS2 A;  5FO8 C;  1ELV A;  1OK3 A;  1GHQ B;  2G7I A;  4AYE A;  1CKL A;  2RKZ A;  4ONT D;  1PPQ A;  4J38 B;  4AYM A;  3GXE A;  2RL0 A;  1OK1 A;  1OK9 A;  4MUC A;  2XWB F;  5HYT B;  1H04 P;  1HCC A;  1TPN A;  3VWO A;  3NJA A;  1ZJK A;  3OXU D;  1GPZ A;  3EJH A;  2MCY A;  4PO7 A;  2BZM A;  4KKD A;  2V8E A;  2W81 A;  3L89 M;  3FGR A;  1H2P P;  5DN5 A;  1OJY A;  2EC3 A;  3KXV A;  4ZH1 D;  3MQL A;  5DN4 A;  2IZ4 A;  2RLP A;  1MD7 A;  3M7P A;  3CI0 J;  1OK2 A;  2Y8R A;  3R62 A;  2QY0 A;  2MCZ A;  3ZLD A;  2Y8T A;  1O9A A;  2KRI A;  2IZ3 A;  3ZD2 A;  1C1Z A;  3IU3 I;  4B2S A;  1GKN A;  1Q3X A;  3INB C;  1E8B A;  4FXG G;  1H03 P;  1SRZ A;  2UWN A;  1QUB A;  3RJ3 D;  2XRB A;  1MD8 A;  4PZ5 A;  4C16 A;  2CG7 A;  2LOJ A;  2ZYC A;  2Y8S A;  1H2Q P;  2ERJ A;  3O8E B;  4AYI A;  4WJG 2;  4YIZ A;  4CSY A;  4BWC A;  5HZP B;  1OJW A;  4B2R A;  4A5W B;  1U5M A;  2CKU A;  5I0Q B;  3SW0 X;  4IGD A;  1GKG A;  1E88 A;  4AYD A;  3WSX A;  2WII C;  1TPM A;  1QGB A;  4LOS A;  4N7E A;  1FBR A;  1G4G A;  1NWV A;  4DJZ A;  2EHF A;  4K12 A;  3CAL A;  4JHS A;  1Z92 B;  2XQW C;  1OJV A;  1HFH A;  2JRA A;  2O39 C;  3NFP I;  5HYU B;  1LY2 A;  4APL A;  2RKY A;  3ZLE A;  2KMS A;  2XWJ I;  2JGX A;  1UOT P;  3KZJ A;  1RLH A;  3T5O A;  3OED C;  1G4F A;  1HFI A;  4F4O C;  4LOT A;  5HYP A;  2B5I D;  3GOV A;  3ZRZ A;  2CG6 A;  2YRA A;  1VVD A;  4YNX A;  2RLQ A;  2JGW A;  3FGT A;  2W80 A;  1TPG A; 
#chains in the Genus database with same CATH homology
 5JPM G;  2YBY A;  3IX0 A;  1E5G A;  2XRD A;  3TVJ A;  1VVC A;  3OP8 A;  3ZD1 A;  3ERB A;  1QO6 A;  2A55 A;  1SS2 A;  5FO8 C;  1ELV A;  1OK3 A;  1GHQ B;  2G7I A;  4AYE A;  1CKL A;  2RKZ A;  4ONT D;  1PPQ A;  4J38 B;  4AYM A;  3GXE A;  2RL0 A;  1OK1 A;  1OK9 A;  4MUC A;  2XWB F;  5HYT B;  1H04 P;  1HCC A;  1TPN A;  1ZJK A;  3OXU D;  1GPZ A;  3EJH A;  2MCY A;  2BZM A;  4KKD A;  2V8E A;  2W81 A;  3L89 M;  1H2P P;  1OJY A;  2EC3 A;  3KXV A;  4ZH1 D;  3MQL A;  2IZ4 A;  2RLP A;  1MD7 A;  3M7P A;  1OK2 A;  3R62 A;  2QY0 A;  2MCZ A;  1O9A A;  2KRI A;  2IZ3 A;  3ZD2 A;  1C1Z A;  3IU3 I;  4B2S A;  1GKN A;  1Q3X A;  3INB C;  1E8B A;  4FXG G;  1H03 P;  1SRZ A;  2UWN A;  1QUB A;  3RJ3 D;  2XRB A;  1MD8 A;  4PZ5 A;  4C16 A;  2CG7 A;  2LOJ A;  1H2Q P;  2ERJ A;  3O8E B;  4AYI A;  4WJG 2;  4CSY A;  5HZP B;  1OJW A;  4B2R A;  4A5W B;  1U5M A;  2CKU A;  5I0Q B;  3SW0 X;  4IGD A;  1GKG A;  1E88 A;  4AYD A;  2WII C;  1TPM A;  1QGB A;  4LOS A;  1FBR A;  1G4G A;  1NWV A;  4DJZ A;  2EHF A;  4K12 A;  3CAL A;  4JHS A;  1Z92 B;  2XQW C;  1OJV A;  1HFH A;  2JRA A;  2O39 C;  3NFP I;  5HYU B;  1LY2 A;  2RKY A;  2KMS A;  2XWJ I;  2JGX A;  1UOT P;  3KZJ A;  3T5O A;  3OED C;  1G4F A;  1HFI A;  4F4O C;  4LOT A;  5HYP A;  2B5I D;  3GOV A;  3ZRZ A;  2CG6 A;  2YRA A;  1VVD A;  4YNX A;  2RLQ A;  2JGW A;  2W80 A;  1TPG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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