1TWAL

Rna polymerase ii complexed with atp
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II largest subunit
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1twaL00
5IYCL 3S1QL 1Y1VL 2NVTL 3GTGL 4BBRL 4A3IL 2NVXL 4BY7L 3HOZL 4X6AL 4Y52L 3HOVL 3FKIL 4A3CL 3GTJL 4BXXL 2NVQL 5C4JL 1K83L 4C3JL 2E2IL 3GTKL 1I6HL 2B63L 4C3HL 3RZOL 3HKZP 2JA8L 4QIWP 2R93L 5IP7L 5M5YL 3S14L 2NVYL 4BBSL 5M3ML 3HOYL 5M5WL 2VUML 3GTML 3S1ML 4A3GL 4BY1L 2Y0SP 3S15L 2PMZP 5M3FL 2R7ZL 4Y7NL 3H0GL 4AYBP 1TWFL 2JA7L 3K7AL 4A3JL 3S2DL 1TWAL 4A3BL 3HOXL 2R92L 5FLML 5IP9L 3GTQL 5IYDL 3CQZL 2E2JL 3H3VM 3M3YL 5C44L 3GTLL 4A93L 5M5XL 2WB1P 3S1RL 1I50L 1TWCL 5C3EL 3GTOL 1WCML 2JA5L 3S16L 3PO3L 3RZDL 2YU9L 3S2HL 4A3DL 3S1NL 1TWHL 3GTPL 2WAQP 1R9TL 3HOUL 3I4NL 2JA6L 3HOWL 5IYBL 4A3LL 5C4XL 4A3ML 1Y1WL 4A3KL 3M4OL 4C2M1 4C3IL 4A3FL 4A3EL 3I4ML 3S17L 5FJ8L 1I3QL 3PO2L 1SFOL 1TWGL 2E2HL
chains in the Genus database with same CATH superfamily
3S1QL 3GTGL 1LKMA 3NFPI 4AHZA 1OWCA 3HOZL 3H97A 1IW7D 4AR4A 4A3CL 3GTJL 1BQ9A 1QYBA 2K2DA 2E2IL 4C3JL 2PYAA 2B63L 5AI3A 4UY81 5M5YL 4TVMA 1CAAA 4BBSL 3GTML 4BY1L 1VCXA 4XGHA 1QQTA 3IU3I 2Y0SP 1IU6A 3H9CA 5M3FL 4Y7NL 4POGA 4AR3A 2JA7L 3S2DL 1YK5A 3A44A 4A3BL 2C6AA 2L0ZA 1NXEA 4RXNA 5GADc 7RXNA 1RDGA 3LWRB 2E2JL 3GTLL 5GAEc 4A93L 1RYQA 2XJTA 3PKJA 4E6YA 1C09A 1I50L 5C3EL 1NNQA 2MS3A 4AHWA 4LHLA 3PO3L 3RZDL 4G6BA 3WWLA 4ZN1B 2WAQP 1R9TL 2M6PA 2JI2A 4V196 3I4NL 3HOWL 2AQCA 4A3ML 2NYDA 2KN9A 3QVDA 2CKCA 1E8JA 3PZAA 4A3EL 3LWQB 3JR7A 5FJ8L 2KKDA 1I3QL 3LNLA 4LHNA 2QL0A 1IU5A 5JVH1 5GAGc 5DM71 2RFKB 2C6BA 5IYCL 4YWLA 1CADA 1Y1VL 2PPTA 3PWFA 3J7Z1 3HAXC 5EIOC 3QQCE 4A3IL 3RZ6A 1VZHA 3HOVL 3MSUA 3FKIL 1T9OA 4ME3A 8RXNA 5MFZA 1K83L 3GTKL 2ERSA 2XJUA 2A69D 1Z92B 4C3HL 2AYJA 1WJVA 2R93L 3S14L 5M3ML 3HOYL 5M5WL 4A3GL 2HR5A 2B5ID 3S15L 1R0FA 5MF6A 1BFYA 1YUXA 2XJVA 5AI2A 3HJWB 3K7AL 1BE7A 2DSXA 2EY4E 5FLML 5EINC 2H12A 3GTQL 1R0HA 5C44L 1YV1A 1B13A 5JVG1 2WB1P 2XJQA 1LKOA 3J7Y1 2CR8A 2YU9L 5DM61 2V3BB 4YWMA 4A3DL 3S1NL 1P7PA 3HJYB 3LWPB 4JAGA 5IYBL 2Z3QB 1Y1WL 1R0JA 4U671 1YUZA 3P2AA 4A3FL 3I4ML 2Z3RB 2RDVA 4AR6A 1RWDA 1DX8A 1NXGA 5MGNA 1IROA 2NVXL 4BY7L 4X6AL 3PL5A 3MPSA 1BRFA 2J9UB 4BXXL 1VZIA 1B71A 2NVQL 4ZN3B 3B08B 2M4VA 3RZOL 3H99A 2JA8L 1R0GA 2XJRA 5IP7L 4AHYA 3RYGA 1PFVA 4JAEA 4AI2A 3S1ML 3ZG6A 3WWNB 2R7ZL 1LKPA 2AUSB 3VPBE 3MQKB 3KYVA 1TWAL 5K2ME 5MLC3 4K9FA 2R92L 5IP9L 2ZIXA 3SS2A 2M4YA 5IYDL 3CQZL 2CKAA 3P8BA 2A68D 3M3YL 4JAFA 4JADA 5M5XL 1QCVA 3KYWA 1B2OA 2XJSA 3S1RL 3PIP1 2JA5L 2VL6A 3PIO1 2JI1A 4AR5A 3S2HL 1FHMA 5RXNA 6RXNA 1RDVA 3K35A 3HOUL 2JA6L 5H1Sc 1SMWA 1BQ8A 1S24A 1S30A 2GMGA 1H7VA 2V0FA 4C3IL 1YK4A 3S17L 3FDJA 5IY0A 3H9BA 2PVXA 3B0AB 5GAHc 1TWGL 4TPUA 2NVTL 2JI3A 1RB9A 4AI3A 4BBRL 1LTLA 2APOB 1ZRPA 4Y52L 2HVYC 1JYBA 1OWBA 3KYYA 2PSMC 4GS7D 5C4JL 1B2JA 1PFWA 1I6HL 1ODHA 3HKZP 4AI0A 4QIWP 1T9QA 1SMUA 3LWVB 2NVYL 2M6OA 1R0IA 3PKIA 2VUML 2BE5D 2XJPA 2LCQA 4AI1A 2PMZP 4POFA 1DVBA 1F4LA 2PVEA 1SMMA 4XXBB 5AN9H 3H0GL 4AYBP 1TWFL 4A3JL 3LPEB 3HOXL 1PFUA 1IRNA 3H3VM 2ERJA 2O5JD 4B8CD 2A6ED 2A6HD 1TWCL 3GTOL 1WCML 3S16L 1PFYA 5MFPA 1TWHL 3KYXA 3GTPL 1VZGA 1PZXA 4A3LL 5C4XL 4A3KL 4WFN1 1RYTA 3KYUA 3M4OL 4C2M1 1FHHA 1S2ZA 3RZTA 3LWOB 1T9PA 3PO2L 4AHXA 1SFOL 2V0EA 2E2HL
chains in the Genus database with same CATH topology
5IYCL 3S1QL 1Y1VL 2NVTL 3GTGL 4BBRL 4A3IL 2NVXL 4BY7L 3HOZL 4X6AL 4Y52L 3HOVL 3FKIL 4A3CL 3GTJL 4BXXL 2NVQL 5C4JL 1K83L 4C3JL 2E2IL 3GTKL 1I6HL 2B63L 4C3HL 3RZOL 3HKZP 2JA8L 4QIWP 2R93L 5IP7L 5M5YL 3S14L 2NVYL 4BBSL 5M3ML 3HOYL 5M5WL 2VUML 3GTML 3S1ML 4A3GL 4BY1L 2Y0SP 3S15L 2PMZP 5M3FL 2R7ZL 4Y7NL 3H0GL 4AYBP 1TWFL 2JA7L 3K7AL 4A3JL 3S2DL 1TWAL 4A3BL 3HOXL 2R92L 5FLML 5IP9L 3GTQL 5IYDL 3CQZL 2E2JL 3H3VM 3M3YL 5C44L 3GTLL 4A93L 5M5XL 2WB1P 3S1RL 1I50L 1TWCL 5C3EL 3GTOL 1WCML 2JA5L 3S16L 3PO3L 3RZDL 2YU9L 3S2HL 4A3DL 3S1NL 1TWHL 3GTPL 2WAQP 1R9TL 3HOUL 3I4NL 2JA6L 3HOWL 5IYBL 4A3LL 5C4XL 4A3ML 1Y1WL 4A3KL 3M4OL 4C2M1 4C3IL 4A3FL 4A3EL 3I4ML 3S17L 5FJ8L 1I3QL 3PO2L 1SFOL 1TWGL 2E2HL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYC L;  3S1Q L;  1Y1V L;  2NVT L;  3GTG L;  4BBR L;  4A3I L;  2NVX L;  4BY7 L;  3HOZ L;  4X6A L;  4Y52 L;  3HOV L;  3FKI L;  4A3C L;  3GTJ L;  4BXX L;  2NVQ L;  5C4J L;  1K83 L;  4C3J L;  2E2I L;  3GTK L;  1I6H L;  2B63 L;  4C3H L;  3RZO L;  3HKZ P;  2JA8 L;  4QIW P;  2R93 L;  5IP7 L;  5M5Y L;  3S14 L;  2NVY L;  4BBS L;  5M3M L;  3HOY L;  5M5W L;  2VUM L;  3GTM L;  3S1M L;  4A3G L;  4BY1 L;  2Y0S P;  3S15 L;  2PMZ P;  5M3F L;  2R7Z L;  4Y7N L;  3H0G L;  4AYB P;  1TWF L;  2JA7 L;  3K7A L;  4A3J L;  3S2D L;  1TWA L;  4A3B L;  3HOX L;  2R92 L;  5FLM L;  5IP9 L;  3GTQ L;  5IYD L;  3CQZ L;  2E2J L;  3H3V M;  3M3Y L;  5C44 L;  3GTL L;  4A93 L;  5M5X L;  2WB1 P;  3S1R L;  1I50 L;  1TWC L;  5C3E L;  3GTO L;  1WCM L;  2JA5 L;  3S16 L;  3PO3 L;  3RZD L;  2YU9 L;  3S2H L;  4A3D L;  3S1N L;  1TWH L;  3GTP L;  2WAQ P;  1R9T L;  3HOU L;  3I4N L;  2JA6 L;  3HOW L;  5IYB L;  4A3L L;  5C4X L;  4A3M L;  1Y1W L;  4A3K L;  3M4O L;  4C2M 1;  4C3I L;  4A3F L;  4A3E L;  3I4M L;  3S17 L;  5FJ8 L;  1I3Q L;  3PO2 L;  1SFO L;  1TWG L;  2E2H L; 
#chains in the Genus database with same CATH topology
 3S1Q L;  3GTG L;  1LKM A;  3NFP I;  4AHZ A;  1OWC A;  3HOZ L;  3H97 A;  1IW7 D;  4AR4 A;  4A3C L;  3GTJ L;  1BQ9 A;  1QYB A;  2K2D A;  2E2I L;  4C3J L;  2PYA A;  2B63 L;  5AI3 A;  4UY8 1;  5M5Y L;  4TVM A;  1CAA A;  4BBS L;  3GTM L;  4BY1 L;  1VCX A;  4XGH A;  1QQT A;  3IU3 I;  2Y0S P;  1IU6 A;  3H9C A;  5M3F L;  4Y7N L;  4POG A;  4AR3 A;  2JA7 L;  3S2D L;  1YK5 A;  3A44 A;  4A3B L;  2C6A A;  2L0Z A;  1NXE A;  4RXN A;  5GAD c;  7RXN A;  1RDG A;  3LWR B;  2E2J L;  3GTL L;  5GAE c;  4A93 L;  1RYQ A;  2XJT A;  3PKJ A;  4E6Y A;  1C09 A;  1I50 L;  5C3E L;  1NNQ A;  2MS3 A;  4AHW A;  4LHL A;  3PO3 L;  3RZD L;  4G6B A;  3WWL A;  4ZN1 B;  2WAQ P;  1R9T L;  2M6P A;  2JI2 A;  4V19 6;  3I4N L;  3HOW L;  2AQC A;  4A3M L;  2NYD A;  2KN9 A;  3QVD A;  2CKC A;  1E8J A;  3PZA A;  4A3E L;  3LWQ B;  3JR7 A;  5FJ8 L;  2KKD A;  1I3Q L;  3LNL A;  4LHN A;  2QL0 A;  1IU5 A;  5JVH 1;  5GAG c;  5DM7 1;  2RFK B;  2C6B A;  5IYC L;  4YWL A;  1CAD A;  1Y1V L;  2PPT A;  3PWF A;  3J7Z 1;  3HAX C;  5EIO C;  3QQC E;  4A3I L;  3RZ6 A;  1VZH A;  3HOV L;  3MSU A;  3FKI L;  1T9O A;  4ME3 A;  8RXN A;  5MFZ A;  1K83 L;  3GTK L;  2ERS A;  2XJU A;  2A69 D;  1Z92 B;  4C3H L;  2AYJ A;  1WJV A;  2R93 L;  3S14 L;  5M3M L;  3HOY L;  5M5W L;  4A3G L;  2HR5 A;  2B5I D;  3S15 L;  1R0F A;  5MF6 A;  1BFY A;  1YUX A;  2XJV A;  5AI2 A;  3HJW B;  3K7A L;  1BE7 A;  2DSX A;  2EY4 E;  5FLM L;  5EIN C;  2H12 A;  3GTQ L;  1R0H A;  5C44 L;  1YV1 A;  1B13 A;  5JVG 1;  2WB1 P;  2XJQ A;  1LKO A;  3J7Y 1;  2CR8 A;  2YU9 L;  5DM6 1;  2V3B B;  4YWM A;  4A3D L;  3S1N L;  1P7P A;  3HJY B;  3LWP B;  4JAG A;  5IYB L;  2Z3Q B;  1Y1W L;  1R0J A;  4U67 1;  1YUZ A;  3P2A A;  4A3F L;  3I4M L;  2Z3R B;  2RDV A;  4AR6 A;  1RWD A;  1DX8 A;  1NXG A;  5MGN A;  1IRO A;  2NVX L;  4BY7 L;  4X6A L;  3PL5 A;  3MPS A;  1BRF A;  2J9U B;  4BXX L;  1VZI A;  1B71 A;  2NVQ L;  4ZN3 B;  3B08 B;  2M4V A;  3RZO L;  3H99 A;  2JA8 L;  1R0G A;  2XJR A;  5IP7 L;  4AHY A;  3RYG A;  1PFV A;  4JAE A;  4AI2 A;  3S1M L;  3ZG6 A;  3WWN B;  2R7Z L;  1LKP A;  2AUS B;  3VPB E;  3MQK B;  3KYV A;  1TWA L;  5K2M E;  5MLC 3;  4K9F A;  2R92 L;  5IP9 L;  2ZIX A;  3SS2 A;  2M4Y A;  5IYD L;  3CQZ L;  2CKA A;  3P8B A;  2A68 D;  3M3Y L;  4JAF A;  4JAD A;  5M5X L;  1QCV A;  3KYW A;  1B2O A;  2XJS A;  3S1R L;  3PIP 1;  2JA5 L;  2VL6 A;  3PIO 1;  2JI1 A;  4AR5 A;  3S2H L;  1FHM A;  5RXN A;  6RXN A;  1RDV A;  3K35 A;  3HOU L;  2JA6 L;  5H1S c;  1SMW A;  1BQ8 A;  1S24 A;  1S30 A;  2GMG A;  1H7V A;  2V0F A;  4C3I L;  1YK4 A;  3S17 L;  3FDJ A;  5IY0 A;  3H9B A;  2PVX A;  3B0A B;  5GAH c;  1TWG L;  4TPU A;  2NVT L;  2JI3 A;  1RB9 A;  4AI3 A;  4BBR L;  1LTL A;  2APO B;  1ZRP A;  4Y52 L;  2HVY C;  1JYB A;  1OWB A;  3KYY A;  2PSM C;  4GS7 D;  5C4J L;  1B2J A;  1PFW A;  1I6H L;  1ODH A;  3HKZ P;  4AI0 A;  4QIW P;  1T9Q A;  1SMU A;  3LWV B;  2NVY L;  2M6O A;  1R0I A;  3PKI A;  2VUM L;  2BE5 D;  2XJP A;  2LCQ A;  4AI1 A;  2PMZ P;  4POF A;  1DVB A;  1F4L A;  2PVE A;  1SMM A;  4XXB B;  5AN9 H;  3H0G L;  4AYB P;  1TWF L;  4A3J L;  3LPE B;  3HOX L;  1PFU A;  1IRN A;  3H3V M;  2ERJ A;  2O5J D;  4B8C D;  2A6E D;  2A6H D;  1TWC L;  3GTO L;  1WCM L;  3S16 L;  1PFY A;  5MFP A;  1TWH L;  3KYX A;  3GTP L;  1VZG A;  1PZX A;  4A3L L;  5C4X L;  4A3K L;  4WFN 1;  1RYT A;  3KYU A;  3M4O L;  4C2M 1;  1FHH A;  1S2Z A;  3RZT A;  3LWO B;  1T9P A;  3PO2 L;  4AHX A;  1SFO L;  2V0E A;  2E2H L; 
#chains in the Genus database with same CATH homology
 5IYC L;  3S1Q L;  1Y1V L;  2NVT L;  3GTG L;  4BBR L;  4A3I L;  2NVX L;  4BY7 L;  3HOZ L;  4X6A L;  4Y52 L;  3HOV L;  3FKI L;  4A3C L;  3GTJ L;  4BXX L;  2NVQ L;  5C4J L;  1K83 L;  4C3J L;  2E2I L;  3GTK L;  1I6H L;  2B63 L;  4C3H L;  3RZO L;  3HKZ P;  2JA8 L;  4QIW P;  2R93 L;  5IP7 L;  5M5Y L;  3S14 L;  2NVY L;  4BBS L;  5M3M L;  3HOY L;  5M5W L;  2VUM L;  3GTM L;  3S1M L;  4A3G L;  4BY1 L;  2Y0S P;  3S15 L;  2PMZ P;  5M3F L;  2R7Z L;  4Y7N L;  3H0G L;  4AYB P;  1TWF L;  2JA7 L;  3K7A L;  4A3J L;  3S2D L;  1TWA L;  4A3B L;  3HOX L;  2R92 L;  5FLM L;  5IP9 L;  3GTQ L;  5IYD L;  3CQZ L;  2E2J L;  3H3V M;  3M3Y L;  5C44 L;  3GTL L;  4A93 L;  5M5X L;  2WB1 P;  3S1R L;  1I50 L;  1TWC L;  5C3E L;  3GTO L;  1WCM L;  2JA5 L;  3S16 L;  3PO3 L;  3RZD L;  2YU9 L;  3S2H L;  4A3D L;  3S1N L;  1TWH L;  3GTP L;  2WAQ P;  1R9T L;  3HOU L;  3I4N L;  2JA6 L;  3HOW L;  5IYB L;  4A3L L;  5C4X L;  4A3M L;  1Y1W L;  4A3K L;  3M4O L;  4C2M 1;  4C3I L;  4A3F L;  4A3E L;  3I4M L;  3S17 L;  5FJ8 L;  1I3Q L;  3PO2 L;  1SFO L;  1TWG L;  2E2H L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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