1TWFL

Rna polymerase ii complexed with utp at 2.3 a resolution
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II largest subunit
molecule tags Transcription
total genus 1
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 1twfL00
1Y1WL 5IP9L 5C3EL 3CQZL 4A3ML 4A3GL 4A3DL 4BY1L 2NVQL 5IP7L 4C3IL 2JA8L 3HOXL 3S1NL 5FLML 4C3HL 2Y0SP 4QIWP 1TWCL 2E2HL 3HOVL 3HOYL 1WCML 3I4ML 3S1QL 3GTJL 2R92L 5M5WL 4Y52L 3S1RL 3GTGL 4A3FL 1TWFL 4Y7NL 1I6HL 4X6AL 4BXXL 3RZOL 3HKZP 2NVXL 2R93L 3S15L 3PO3L 1TWGL 2VUML 4A3LL 5M3ML 4C2M1 3GTPL 3HOZL 4A3EL 1Y1VL 2E2JL 3H3VM 5C44L 4BY7L 3HOWL 1TWAL 3I4NL 2NVTL 3FKIL 2E2IL 5M5XL 4BBRL 1R9TL 3S2HL 5M3FL 2JA6L 1I50L 1TWHL 4BBSL 2JA7L 3S17L 2JA5L 5IYBL 2WAQP 3GTML 2WB1P 2PMZP 3S16L 5FJ8L 3RZDL 3K7AL 5M5YL 4A3JL 3PO2L 3GTOL 5C4JL 1I3QL 2NVYL 4A3CL 5C4XL 5IYDL 3GTKL 3H0GL 4A3BL 3M4OL 2R7ZL 2YU9L 3S2DL 4C3JL 4A3KL 3HOUL 3S14L 1SFOL 3GTLL 3S1ML 3GTQL 4A93L 4AYBP 5IYCL 3M3YL 2B63L 1K83L 4A3IL
chains in the Genus database with same CATH superfamily
5C3EL 1IROA 1NXGA 4A3GL 4ZN3B 3MPSA 2PPTA 3ZG6A 1PZXA 3B0AB 2QL0A 2ERSA 1PFWA 4C3IL 1T9PA 2XJUA 1LKPA 5FLML 2APOB 2XJPA 3LNLA 4QIWP 3PKIA 1E8JA 4ZN1B 1SMWA 3B08B 3H97A 1VZIA 5MFPA 3LWVB 3GTGL 4Y7NL 3MQKB 3LWOB 3S15L 3PO3L 2JI2A 3PL5A 4C2M1 2B5ID 2Z3QB 3P8BA 4A3EL 1Y1VL 1YUZA 3H3VM 1YK4A 5AI3A 1R9TL 4G6BA 2KN9A 2L0ZA 7RXNA 2JA7L 2JA5L 2V0EA 2CKAA 1R0IA 3VPBE 2PMZP 2K2DA 4A3JL 1CAAA 3PO2L 1I3QL 1BE7A 1YK5A 5C4XL 1YUXA 1NNQA 3J7Y1 4RXNA 3H0GL 2PVEA 2HVYC 1FHHA 3M4OL 1IW7D 4AR4A 2V0FA 3S2DL 1S30A 3H9CA 3HOUL 3S14L 4E6YA 2NYDA 4LHLA 4AYBP 3H9BA 5IP9L 2J9UB 1B2OA 1CADA 5MLC3 2A6HD 4AR5A 3FDJA 2JA8L 4XGHA 3HOXL 1DX8A 2XJRA 4ME3A 4C3HL 4AI2A 2Y0SP 1DVBA 1WCML 1QCVA 3S1QL 3QVDA 3GTJL 2R92L 5RXNA 4AHYA 4X6AL 2M6PA 4JAGA 4BXXL 3RZOL 3HKZP 1YV1A 2NVXL 2V3BB 4A3LL 6RXNA 4JAEA 2RDVA 3HOZL 2E2JL 1PFVA 2BE5D 3KYYA 2M4VA 1VZHA 3LWQB 1SMUA 4XXBB 5IY0A 4POFA 5M3FL 1I50L 2C6AA 4UY81 2CR8A 2O5JD 4BBSL 1F4LA 3S17L 2Z3RB 1T9OA 2ERJA 5GAGc 4V196 1QQTA 2WB1P 5AN9H 3RZDL 3K7AL 5M5YL 2XJVA 3H99A 5GADc 4WFN1 5DM71 3GTOL 5C4JL 3WWLA 1RDVA 2XJSA 2KKDA 2XJTA 5IYDL 1B2JA 1RYQA 4A3BL 1T9QA 1PFYA 2R7ZL 5EIOC 4A93L 4GS7D 5IYCL 4AI3A 1R0HA 1Y1WL 3CQZL 3PZAA 1LTLA 1C09A 3LWPB 3PWFA 2C6BA 3KYVA 3S1NL 4AHWA 5GAHc 3KYXA 2AYJA 4AI1A 1TWCL 2E2HL 3HOYL 3RYGA 4TVMA 4TPUA 4Y52L 3S1RL 2CKCA 4AR3A 1P7PA 4A3FL 2PYAA 5GAEc 2AUSB 2R93L 3A44A 2ZIXA 3K35A 1BRFA 2VUML 1RYTA 1RWDA 2A69D 3GTPL 1QYBA 1S2ZA 1BQ9A 2DSXA 4AHXA 5C44L 3HOWL 1OWBA 1TWAL 3I4NL 2NVTL 3FKIL 2E2IL 5M5XL 1B71A 3S2HL 3PIP1 1R0GA 2A68D 1TWHL 1IU6A 4LHNA 3IU3I 4JADA 4K9FA 5IYBL 3GTML 2VL6A 3S16L 5MF6A 5JVH1 3KYUA 4YWLA 4YWMA 1LKMA 2NVYL 1JYBA 3SS2A 2XJQA 1NXEA 2JI1A 2YU9L 3GTLL 3RZTA 3GTQL 2H12A 1LKOA 1BFYA 1B13A 2B63L 1FHMA 4A3ML 3NFPI 2JI3A 1RDGA 3HAXC 4BY1L 4A3DL 1IRNA 2PSMC 2NVQL 5IP7L 4AI0A 5MFZA 1PFUA 5K2ME 5H1Sc 2HR5A 3PKJA 8RXNA 3HOVL 1IU5A 4AR6A 2RFKB 1S24A 3I4ML 2EY4E 1Z92B 3HJWB 5M5WL 3RZ6A 5EINC 3LPEB 1TWFL 1I6HL 4AHZA 1OWCA 3JR7A 5JVG1 1TWGL 2M6OA 1VZGA 1WJVA 5M3ML 1SMMA 4POGA 5DM61 3LWRB 1BQ8A 3HJYB 2MS3A 2PVXA 4BY7L 1R0FA 1RB9A 4BBRL 1VCXA 2LCQA 2JA6L 3PIO1 1R0JA 3WWNB 2WAQP 2M4YA 1ZRPA 3KYWA 5FJ8L 3MSUA 2GMGA 4A3CL 4U671 2AQCA 3GTKL 4B8CD 5MGNA 4C3JL 4JAFA 4A3KL 1SFOL 3S1ML 3P2AA 3J7Z1 1H7VA 5AI2A 1ODHA 3QQCE 3M3YL 1K83L 2A6ED 4A3IL
chains in the Genus database with same CATH topology
1Y1WL 5IP9L 5C3EL 3CQZL 4A3ML 4A3GL 4A3DL 4BY1L 2NVQL 5IP7L 4C3IL 2JA8L 3HOXL 3S1NL 5FLML 4C3HL 2Y0SP 4QIWP 1TWCL 2E2HL 3HOVL 3HOYL 1WCML 3I4ML 3S1QL 3GTJL 2R92L 5M5WL 4Y52L 3S1RL 3GTGL 4A3FL 1TWFL 4Y7NL 1I6HL 4X6AL 4BXXL 3RZOL 3HKZP 2NVXL 2R93L 3S15L 3PO3L 1TWGL 2VUML 4A3LL 5M3ML 4C2M1 3GTPL 3HOZL 4A3EL 1Y1VL 2E2JL 3H3VM 5C44L 4BY7L 3HOWL 1TWAL 3I4NL 2NVTL 3FKIL 2E2IL 5M5XL 4BBRL 1R9TL 3S2HL 5M3FL 2JA6L 1I50L 1TWHL 4BBSL 2JA7L 3S17L 2JA5L 5IYBL 2WAQP 3GTML 2WB1P 2PMZP 3S16L 5FJ8L 3RZDL 3K7AL 5M5YL 4A3JL 3PO2L 3GTOL 5C4JL 1I3QL 2NVYL 4A3CL 5C4XL 5IYDL 3GTKL 3H0GL 4A3BL 3M4OL 2R7ZL 2YU9L 3S2DL 4C3JL 4A3KL 3HOUL 3S14L 1SFOL 3GTLL 3S1ML 3GTQL 4A93L 4AYBP 5IYCL 3M3YL 2B63L 1K83L 4A3IL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1W L;  5IP9 L;  5C3E L;  3CQZ L;  4A3M L;  4A3G L;  4A3D L;  4BY1 L;  2NVQ L;  5IP7 L;  4C3I L;  2JA8 L;  3HOX L;  3S1N L;  5FLM L;  4C3H L;  2Y0S P;  4QIW P;  1TWC L;  2E2H L;  3HOV L;  3HOY L;  1WCM L;  3I4M L;  3S1Q L;  3GTJ L;  2R92 L;  5M5W L;  4Y52 L;  3S1R L;  3GTG L;  4A3F L;  1TWF L;  4Y7N L;  1I6H L;  4X6A L;  4BXX L;  3RZO L;  3HKZ P;  2NVX L;  2R93 L;  3S15 L;  3PO3 L;  1TWG L;  2VUM L;  4A3L L;  5M3M L;  4C2M 1;  3GTP L;  3HOZ L;  4A3E L;  1Y1V L;  2E2J L;  3H3V M;  5C44 L;  4BY7 L;  3HOW L;  1TWA L;  3I4N L;  2NVT L;  3FKI L;  2E2I L;  5M5X L;  4BBR L;  1R9T L;  3S2H L;  5M3F L;  2JA6 L;  1I50 L;  1TWH L;  4BBS L;  2JA7 L;  3S17 L;  2JA5 L;  5IYB L;  2WAQ P;  3GTM L;  2WB1 P;  2PMZ P;  3S16 L;  5FJ8 L;  3RZD L;  3K7A L;  5M5Y L;  4A3J L;  3PO2 L;  3GTO L;  5C4J L;  1I3Q L;  2NVY L;  4A3C L;  5C4X L;  5IYD L;  3GTK L;  3H0G L;  4A3B L;  3M4O L;  2R7Z L;  2YU9 L;  3S2D L;  4C3J L;  4A3K L;  3HOU L;  3S14 L;  1SFO L;  3GTL L;  3S1M L;  3GTQ L;  4A93 L;  4AYB P;  5IYC L;  3M3Y L;  2B63 L;  1K83 L;  4A3I L; 
#chains in the Genus database with same CATH topology
 5C3E L;  1IRO A;  1NXG A;  4A3G L;  4ZN3 B;  3MPS A;  2PPT A;  3ZG6 A;  1PZX A;  3B0A B;  2QL0 A;  2ERS A;  1PFW A;  4C3I L;  1T9P A;  2XJU A;  1LKP A;  5FLM L;  2APO B;  2XJP A;  3LNL A;  4QIW P;  3PKI A;  1E8J A;  4ZN1 B;  1SMW A;  3B08 B;  3H97 A;  1VZI A;  5MFP A;  3LWV B;  3GTG L;  4Y7N L;  3MQK B;  3LWO B;  3S15 L;  3PO3 L;  2JI2 A;  3PL5 A;  4C2M 1;  2B5I D;  2Z3Q B;  3P8B A;  4A3E L;  1Y1V L;  1YUZ A;  3H3V M;  1YK4 A;  5AI3 A;  1R9T L;  4G6B A;  2KN9 A;  2L0Z A;  7RXN A;  2JA7 L;  2JA5 L;  2V0E A;  2CKA A;  1R0I A;  3VPB E;  2PMZ P;  2K2D A;  4A3J L;  1CAA A;  3PO2 L;  1I3Q L;  1BE7 A;  1YK5 A;  5C4X L;  1YUX A;  1NNQ A;  3J7Y 1;  4RXN A;  3H0G L;  2PVE A;  2HVY C;  1FHH A;  3M4O L;  1IW7 D;  4AR4 A;  2V0F A;  3S2D L;  1S30 A;  3H9C A;  3HOU L;  3S14 L;  4E6Y A;  2NYD A;  4LHL A;  4AYB P;  3H9B A;  5IP9 L;  2J9U B;  1B2O A;  1CAD A;  5MLC 3;  2A6H D;  4AR5 A;  3FDJ A;  2JA8 L;  4XGH A;  3HOX L;  1DX8 A;  2XJR A;  4ME3 A;  4C3H L;  4AI2 A;  2Y0S P;  1DVB A;  1WCM L;  1QCV A;  3S1Q L;  3QVD A;  3GTJ L;  2R92 L;  5RXN A;  4AHY A;  4X6A L;  2M6P A;  4JAG A;  4BXX L;  3RZO L;  3HKZ P;  1YV1 A;  2NVX L;  2V3B B;  4A3L L;  6RXN A;  4JAE A;  2RDV A;  3HOZ L;  2E2J L;  1PFV A;  2BE5 D;  3KYY A;  2M4V A;  1VZH A;  3LWQ B;  1SMU A;  4XXB B;  5IY0 A;  4POF A;  5M3F L;  1I50 L;  2C6A A;  4UY8 1;  2CR8 A;  2O5J D;  4BBS L;  1F4L A;  3S17 L;  2Z3R B;  1T9O A;  2ERJ A;  5GAG c;  4V19 6;  1QQT A;  2WB1 P;  5AN9 H;  3RZD L;  3K7A L;  5M5Y L;  2XJV A;  3H99 A;  5GAD c;  4WFN 1;  5DM7 1;  3GTO L;  5C4J L;  3WWL A;  1RDV A;  2XJS A;  2KKD A;  2XJT A;  5IYD L;  1B2J A;  1RYQ A;  4A3B L;  1T9Q A;  1PFY A;  2R7Z L;  5EIO C;  4A93 L;  4GS7 D;  5IYC L;  4AI3 A;  1R0H A;  1Y1W L;  3CQZ L;  3PZA A;  1LTL A;  1C09 A;  3LWP B;  3PWF A;  2C6B A;  3KYV A;  3S1N L;  4AHW A;  5GAH c;  3KYX A;  2AYJ A;  4AI1 A;  1TWC L;  2E2H L;  3HOY L;  3RYG A;  4TVM A;  4TPU A;  4Y52 L;  3S1R L;  2CKC A;  4AR3 A;  1P7P A;  4A3F L;  2PYA A;  5GAE c;  2AUS B;  2R93 L;  3A44 A;  2ZIX A;  3K35 A;  1BRF A;  2VUM L;  1RYT A;  1RWD A;  2A69 D;  3GTP L;  1QYB A;  1S2Z A;  1BQ9 A;  2DSX A;  4AHX A;  5C44 L;  3HOW L;  1OWB A;  1TWA L;  3I4N L;  2NVT L;  3FKI L;  2E2I L;  5M5X L;  1B71 A;  3S2H L;  3PIP 1;  1R0G A;  2A68 D;  1TWH L;  1IU6 A;  4LHN A;  3IU3 I;  4JAD A;  4K9F A;  5IYB L;  3GTM L;  2VL6 A;  3S16 L;  5MF6 A;  5JVH 1;  3KYU A;  4YWL A;  4YWM A;  1LKM A;  2NVY L;  1JYB A;  3SS2 A;  2XJQ A;  1NXE A;  2JI1 A;  2YU9 L;  3GTL L;  3RZT A;  3GTQ L;  2H12 A;  1LKO A;  1BFY A;  1B13 A;  2B63 L;  1FHM A;  4A3M L;  3NFP I;  2JI3 A;  1RDG A;  3HAX C;  4BY1 L;  4A3D L;  1IRN A;  2PSM C;  2NVQ L;  5IP7 L;  4AI0 A;  5MFZ A;  1PFU A;  5K2M E;  5H1S c;  2HR5 A;  3PKJ A;  8RXN A;  3HOV L;  1IU5 A;  4AR6 A;  2RFK B;  1S24 A;  3I4M L;  2EY4 E;  1Z92 B;  3HJW B;  5M5W L;  3RZ6 A;  5EIN C;  3LPE B;  1TWF L;  1I6H L;  4AHZ A;  1OWC A;  3JR7 A;  5JVG 1;  1TWG L;  2M6O A;  1VZG A;  1WJV A;  5M3M L;  1SMM A;  4POG A;  5DM6 1;  3LWR B;  1BQ8 A;  3HJY B;  2MS3 A;  2PVX A;  4BY7 L;  1R0F A;  1RB9 A;  4BBR L;  1VCX A;  2LCQ A;  2JA6 L;  3PIO 1;  1R0J A;  3WWN B;  2WAQ P;  2M4Y A;  1ZRP A;  3KYW A;  5FJ8 L;  3MSU A;  2GMG A;  4A3C L;  4U67 1;  2AQC A;  3GTK L;  4B8C D;  5MGN A;  4C3J L;  4JAF A;  4A3K L;  1SFO L;  3S1M L;  3P2A A;  3J7Z 1;  1H7V A;  5AI2 A;  1ODH A;  3QQC E;  3M3Y L;  1K83 L;  2A6E D;  4A3I L; 
#chains in the Genus database with same CATH homology
 1Y1W L;  5IP9 L;  5C3E L;  3CQZ L;  4A3M L;  4A3G L;  4A3D L;  4BY1 L;  2NVQ L;  5IP7 L;  4C3I L;  2JA8 L;  3HOX L;  3S1N L;  5FLM L;  4C3H L;  2Y0S P;  4QIW P;  1TWC L;  2E2H L;  3HOV L;  3HOY L;  1WCM L;  3I4M L;  3S1Q L;  3GTJ L;  2R92 L;  5M5W L;  4Y52 L;  3S1R L;  3GTG L;  4A3F L;  1TWF L;  4Y7N L;  1I6H L;  4X6A L;  4BXX L;  3RZO L;  3HKZ P;  2NVX L;  2R93 L;  3S15 L;  3PO3 L;  1TWG L;  2VUM L;  4A3L L;  5M3M L;  4C2M 1;  3GTP L;  3HOZ L;  4A3E L;  1Y1V L;  2E2J L;  3H3V M;  5C44 L;  4BY7 L;  3HOW L;  1TWA L;  3I4N L;  2NVT L;  3FKI L;  2E2I L;  5M5X L;  4BBR L;  1R9T L;  3S2H L;  5M3F L;  2JA6 L;  1I50 L;  1TWH L;  4BBS L;  2JA7 L;  3S17 L;  2JA5 L;  5IYB L;  2WAQ P;  3GTM L;  2WB1 P;  2PMZ P;  3S16 L;  5FJ8 L;  3RZD L;  3K7A L;  5M5Y L;  4A3J L;  3PO2 L;  3GTO L;  5C4J L;  1I3Q L;  2NVY L;  4A3C L;  5C4X L;  5IYD L;  3GTK L;  3H0G L;  4A3B L;  3M4O L;  2R7Z L;  2YU9 L;  3S2D L;  4C3J L;  4A3K L;  3HOU L;  3S14 L;  1SFO L;  3GTL L;  3S1M L;  3GTQ L;  4A93 L;  4AYB P;  5IYC L;  3M3Y L;  2B63 L;  1K83 L;  4A3I L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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