1U68A

Dhna 7,8 dihydroneopterin complex
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
121
structure length
121
Chain Sequence
MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLSEAGRTDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKENPPIPGHYDGVGIEIVRENK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Dihydroneopterin aldolase
publication title Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 30
structure length 121
sequence length 121
ec nomenclature ec 4.1.2.25: Dihydroneopterin aldolase.
pdb deposition date 2004-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02152 FolB Dihydroneopterin aldolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1130.10 Alpha Beta 2-Layer Sandwich GTP Cyclohydrolase I, domain 2 GTP Cyclohydrolase I, domain 2 1u68A00
1DHNA 3RJ4A 1N3TA 3O1KA 3S19A 1RRIA 1NBUC 1SQLA 1RS2A 1Z9WA 1FBXA 4GHMA 1U68A 1A8RA 1FB1A 2NM3A 4IQIA 4AEYA 2DHNA 5F3MA 2NM2A 1IS8A 3UXJA 1GTPA 1B9LA 4FGCA 1WPLA 4F8BA 1NBUA 1RSIA 4UQFA 3V9OA 3BP1A 3RZPA 1WUQA 2O90A 1N3RA 1RSDA 5FARA 1RRYA 3R2EA 1WURA 1RRWA 1A9CA 1N3SA 1NBUB 1RS4A 2CG8A 3UXVA 4DU6A 1WM9A 1IS7A
chains in the Genus database with same CATH superfamily
1DHNA 3RJ4A 1N3TA 3O1KA 3S19A 1RRIA 1NBUC 1SQLA 1RS2A 1Z9WA 1FBXA 4GHMA 1U68A 1A8RA 1FB1A 2NM3A 4IQIA 4AEYA 2DHNA 5F3MA 2NM2A 1IS8A 3UXJA 1GTPA 1B9LA 4FGCA 1WPLA 4F8BA 1NBUA 1RSIA 4UQFA 3V9OA 3BP1A 3RZPA 1WUQA 2O90A 1N3RA 1RSDA 5FARA 1RRYA 3R2EA 1WURA 1RRWA 1A9CA 1N3SA 1NBUB 1RS4A 2CG8A 3UXVA 4DU6A 1WM9A 1IS7A
chains in the Genus database with same CATH topology
1DHNA 3RJ4A 1N3TA 3O1KA 3S19A 1RRIA 1NBUC 1SQLA 1RS2A 1Z9WA 1FBXA 4GHMA 1U68A 1A8RA 1FB1A 2NM3A 4IQIA 4AEYA 2DHNA 5F3MA 2NM2A 1IS8A 3UXJA 1GTPA 1B9LA 4FGCA 1WPLA 4F8BA 1NBUA 1RSIA 4UQFA 3V9OA 3BP1A 3RZPA 1WUQA 2O90A 1N3RA 1RSDA 5FARA 1RRYA 3R2EA 1WURA 1RRWA 1A9CA 1N3SA 1NBUB 1RS4A 2CG8A 3UXVA 4DU6A 1WM9A 1IS7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DHN A;  3RJ4 A;  1N3T A;  3O1K A;  3S19 A;  1RRI A;  1NBU C;  1SQL A;  1RS2 A;  1Z9W A;  1FBX A;  4GHM A;  1U68 A;  1A8R A;  1FB1 A;  2NM3 A;  4IQI A;  4AEY A;  2DHN A;  5F3M A;  2NM2 A;  1IS8 A;  3UXJ A;  1GTP A;  1B9L A;  4FGC A;  1WPL A;  4F8B A;  1NBU A;  1RSI A;  4UQF A;  3V9O A;  3BP1 A;  3RZP A;  1WUQ A;  2O90 A;  1N3R A;  1RSD A;  5FAR A;  1RRY A;  3R2E A;  1WUR A;  1RRW A;  1A9C A;  1N3S A;  1NBU B;  1RS4 A;  2CG8 A;  3UXV A;  4DU6 A;  1WM9 A;  1IS7 A; 
#chains in the Genus database with same CATH topology
 1DHN A;  3RJ4 A;  1N3T A;  3O1K A;  3S19 A;  1RRI A;  1NBU C;  1SQL A;  1RS2 A;  1Z9W A;  1FBX A;  4GHM A;  1U68 A;  1A8R A;  1FB1 A;  2NM3 A;  4IQI A;  4AEY A;  2DHN A;  5F3M A;  2NM2 A;  1IS8 A;  3UXJ A;  1GTP A;  1B9L A;  4FGC A;  1WPL A;  4F8B A;  1NBU A;  1RSI A;  4UQF A;  3V9O A;  3BP1 A;  3RZP A;  1WUQ A;  2O90 A;  1N3R A;  1RSD A;  5FAR A;  1RRY A;  3R2E A;  1WUR A;  1RRW A;  1A9C A;  1N3S A;  1NBU B;  1RS4 A;  2CG8 A;  3UXV A;  4DU6 A;  1WM9 A;  1IS7 A; 
#chains in the Genus database with same CATH homology
 1DHN A;  3RJ4 A;  1N3T A;  3O1K A;  3S19 A;  1RRI A;  1NBU C;  1SQL A;  1RS2 A;  1Z9W A;  1FBX A;  4GHM A;  1U68 A;  1A8R A;  1FB1 A;  2NM3 A;  4IQI A;  4AEY A;  2DHN A;  5F3M A;  2NM2 A;  1IS8 A;  3UXJ A;  1GTP A;  1B9L A;  4FGC A;  1WPL A;  4F8B A;  1NBU A;  1RSI A;  4UQF A;  3V9O A;  3BP1 A;  3RZP A;  1WUQ A;  2O90 A;  1N3R A;  1RSD A;  5FAR A;  1RRY A;  3R2E A;  1WUR A;  1RRW A;  1A9C A;  1N3S A;  1NBU B;  1RS4 A;  2CG8 A;  3UXV A;  4DU6 A;  1WM9 A;  1IS7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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