1UCHA

Deubiquitinating enzyme uch-l3 (human) at 1.8 angstrom resolution
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
Knots found
sequence length
226
structure length
206
Chain Sequence
RWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cysteine protease
molecule keywords UBIQUITIN C-TERMINAL HYDROLASE UCH-L3
publication title Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution.
pubmed doi rcsb
source organism Homo sapiens
total genus 69
structure length 206
sequence length 226
other databases KnotProt 2.0: K -52 -31 -31
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 1997-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01088 Peptidase_C12 Ubiquitin carboxyl-terminal hydrolase, family 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.532.10 Alpha Beta 3-Layer(aba) Sandwich Ubiquitin C-terminal Hydrolase UCH-l3 Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1uchA00
2LENA 3KVFA 4UEMA 1UCHA 4UELA 4IG7A 4DM9A 1CMXA 3IFWA 3IHRA 3KW5A 3TB3A 1XD3A 4JKJA 4I6NA 3IRTA 3RIIA 3RISA 3A7SA 2ETLA
chains in the Genus database with same CATH superfamily
2LENA 3KVFA 4UEMA 1UCHA 4UELA 4IG7A 4DM9A 1CMXA 3IFWA 3IHRA 3KW5A 3TB3A 1XD3A 4JKJA 4I6NA 3IRTA 3RIIA 3RISA 3A7SA 2ETLA
chains in the Genus database with same CATH topology
2LENA 3KVFA 4UEMA 1UCHA 4UELA 4IG7A 4DM9A 1CMXA 3IFWA 3IHRA 3KW5A 3TB3A 1XD3A 4JKJA 4I6NA 3IRTA 3RIIA 3RISA 3A7SA 2ETLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LEN A;  3KVF A;  4UEM A;  1UCH A;  4UEL A;  4IG7 A;  4DM9 A;  1CMX A;  3IFW A;  3IHR A;  3KW5 A;  3TB3 A;  1XD3 A;  4JKJ A;  4I6N A;  3IRT A;  3RII A;  3RIS A;  3A7S A;  2ETL A; 
#chains in the Genus database with same CATH topology
 2LEN A;  3KVF A;  4UEM A;  1UCH A;  4UEL A;  4IG7 A;  4DM9 A;  1CMX A;  3IFW A;  3IHR A;  3KW5 A;  3TB3 A;  1XD3 A;  4JKJ A;  4I6N A;  3IRT A;  3RII A;  3RIS A;  3A7S A;  2ETL A; 
#chains in the Genus database with same CATH homology
 2LEN A;  3KVF A;  4UEM A;  1UCH A;  4UEL A;  4IG7 A;  4DM9 A;  1CMX A;  3IFW A;  3IHR A;  3KW5 A;  3TB3 A;  1XD3 A;  4JKJ A;  4I6N A;  3IRT A;  3RII A;  3RIS A;  3A7S A;  2ETL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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