1UMWA

Structure of a human plk1 polo-box domain/phosphopeptide complex
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
222
structure length
222
Chain Sequence
b'HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SERINE/THREONINE-PROTEIN KINASE PLK
publication title The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 71
structure length 222
sequence length 222
chains with identical sequence B
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2003-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 1umwA02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 1umwA01
4O9WA 4X9VA 4LKMA 1UMWA 4O6WA 3P36A 4HCOA 4HABA 3P2WA 4WHHA 4E9CA 3P35A 4WHKA 3P37A 4X9RA 4E67A 5DMVC 2OJXA 3FVHA 1Q4OA 4J7BB 5LHZA 5DNJA 4LKLA 4WHLA 3BZIA 4E9DA 3HIHA 3P34A 3RQ7A 4XB0A 4DFWA 1Q4KA 5J19A 2OGQA 5DMSA 4O56A 3C5LA 4X9WA 3Q1IA 4H71A 4HY2A 4RS6A 4H5XA 4YYPA 2N19A 3P2ZA 3HIKA 4RCPA
chains in the Genus database with same CATH superfamily
4O6WA 4HCOA 4HABA 1N2LA 4WHKA 1E2TA 5DAYA 4E67A 5DMVC 3FVHA 2IA9A 5AJ9A 4LKLA 4CXSA 4E9DA 4CXUA 1F32A 1Q4KA 3ED4A 4O56A 4YYPA 3Q1IA 4H71A 3P2ZA 3HIKA 4O9WA 4X9VA 3GYVA 4WHHA 3KDRA 3P37A 4X9RA 2OJXA 4NKBA 4NK7A 1E33P 4WHLA 4FDIA 4G7NA 1F34B 4FDJA 3C5LA 4X9WA 4H5XA 4RCPA 2I9XA 4N7VA 4LKMA 1UMWA 3P36A 1E2SP 2QZUA 3P2WA 3P35A 3GYWA 3LXQA 1N2KA 5LHZA 4CYSA 3HIHA 3P34A 4CYRA 3RQ7A 4XB0A 4DFWA 5J19A 2OGQA 5DMSA 4HY2A 1A87A 1FSUA 2VKZG 4N7ZA 4E9CA 1E1ZP 3HMJG 3FS3A 1E3CP 4CXKA 4N9JA 1HDHA 1Q4OA 4J7BB 2UV8G 2I9ZA 5DNJA 3BZIA 3LM3A 3HFDA 1AUKA 1P49A 2E50A 2N19A 4RS6A
chains in the Genus database with same CATH topology
4O9WA 4X9VA 4LKMA 1UMWA 4O6WA 3P36A 4HCOA 4HABA 3P2WA 4WHHA 4E9CA 3P35A 4WHKA 3P37A 4X9RA 4E67A 5DMVC 2OJXA 3FVHA 1Q4OA 4J7BB 5LHZA 5DNJA 4LKLA 4WHLA 3BZIA 4E9DA 3HIHA 3P34A 3RQ7A 4XB0A 4DFWA 1Q4KA 5J19A 2OGQA 5DMSA 4O56A 3C5LA 4X9WA 3Q1IA 4H71A 4HY2A 4RS6A 4H5XA 4YYPA 2N19A 3P2ZA 3HIKA 4RCPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O9W A;  4X9V A;  4LKM A;  1UMW A;  4O6W A;  3P36 A;  4HCO A;  4HAB A;  3P2W A;  4WHH A;  4E9C A;  3P35 A;  4WHK A;  3P37 A;  4X9R A;  4E67 A;  5DMV C;  2OJX A;  3FVH A;  1Q4O A;  4J7B B;  5LHZ A;  5DNJ A;  4LKL A;  4WHL A;  3BZI A;  4E9D A;  3HIH A;  3P34 A;  3RQ7 A;  4XB0 A;  4DFW A;  1Q4K A;  5J19 A;  2OGQ A;  5DMS A;  4O56 A;  3C5L A;  4X9W A;  3Q1I A;  4H71 A;  4HY2 A;  4RS6 A;  4H5X A;  4YYP A;  2N19 A;  3P2Z A;  3HIK A;  4RCP A; 
#chains in the Genus database with same CATH topology
 4O6W A;  4HCO A;  4HAB A;  1N2L A;  4WHK A;  1E2T A;  5DAY A;  4E67 A;  5DMV C;  3FVH A;  2IA9 A;  5AJ9 A;  4LKL A;  4CXS A;  4E9D A;  4CXU A;  1F32 A;  1Q4K A;  3ED4 A;  4O56 A;  4YYP A;  3Q1I A;  4H71 A;  3P2Z A;  3HIK A;  4O9W A;  4X9V A;  3GYV A;  4WHH A;  3KDR A;  3P37 A;  4X9R A;  2OJX A;  4NKB A;  4NK7 A;  1E33 P;  4WHL A;  4FDI A;  4G7N A;  1F34 B;  4FDJ A;  3C5L A;  4X9W A;  4H5X A;  4RCP A;  2I9X A;  4N7V A;  4LKM A;  1UMW A;  3P36 A;  1E2S P;  2QZU A;  3P2W A;  3P35 A;  3GYW A;  3LXQ A;  1N2K A;  5LHZ A;  4CYS A;  3HIH A;  3P34 A;  4CYR A;  3RQ7 A;  4XB0 A;  4DFW A;  5J19 A;  2OGQ A;  5DMS A;  4HY2 A;  1A87 A;  1FSU A;  2VKZ G;  4N7Z A;  4E9C A;  1E1Z P;  3HMJ G;  3FS3 A;  1E3C P;  4CXK A;  4N9J A;  1HDH A;  1Q4O A;  4J7B B;  2UV8 G;  2I9Z A;  5DNJ A;  3BZI A;  3LM3 A;  3HFD A;  1AUK A;  1P49 A;  2E50 A;  2N19 A;  4RS6 A; 
#chains in the Genus database with same CATH homology
 4O9W A;  4X9V A;  4LKM A;  1UMW A;  4O6W A;  3P36 A;  4HCO A;  4HAB A;  3P2W A;  4WHH A;  4E9C A;  3P35 A;  4WHK A;  3P37 A;  4X9R A;  4E67 A;  5DMV C;  2OJX A;  3FVH A;  1Q4O A;  4J7B B;  5LHZ A;  5DNJ A;  4LKL A;  4WHL A;  3BZI A;  4E9D A;  3HIH A;  3P34 A;  3RQ7 A;  4XB0 A;  4DFW A;  1Q4K A;  5J19 A;  2OGQ A;  5DMS A;  4O56 A;  3C5L A;  4X9W A;  3Q1I A;  4H71 A;  4HY2 A;  4RS6 A;  4H5X A;  4YYP A;  2N19 A;  3P2Z A;  3HIK A;  4RCP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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