1UNPA

Crystal structure of the pleckstrin homology domain of pkb alpha
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
119
structure length
119
Chain Sequence
DVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
pubmed doi rcsb
molecule keywords RAC-ALPHA SERINE/THREONINE KINASE
molecule tags Transferase
source organism Homo sapiens
total genus 29
structure length 119
sequence length 119
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2003-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1unpA00
3DXDA 4HAWB 1DROA 4HB2B 3D8DA 2ROZB 3MPXA 4MY6A 5L81A 5J3TA 2G35A 5HE0A 3SUZA 1P5TA 4GXBA 2H7DA 4KHBB 4PQ0A 2W2WA 2J0KA 1BWNA 2NMBA 2DFKA 2Z0QA 1AQCA 4K2OA 1ZVRA 3ZVRA 1U5EA 2K2JA 3KRWA 5D27A 2N23A 4K17A 2LKOA 1DYNA 1NTVA 2UZRA 4GMXB 4K81A 2QKMA 2CRFA 2YS3A 1UPQA 3DXCA 4IFSA 2H7EA 4CYEA 4HDQA 2YS5A 1MK7B 3ODWA 4DXAB 3A98B 3ULCA 2D2QA 3TW1A 1XODA 4D0NB 3N7CA 2FJLA 1EF1A 1I7AA 2ROVA 5DHFB 1FGZA 2W2XD 3HW2B 3AJ4A 1GC6A 2DKPA 1WGUA 1WI1A 3G9WA 1I2HA 2DHKA 2N0YA 5D3VA 1X86A 5HE1A 3NSUA 2GCLA 5D3YA 2OTXA 2OQBA 2AEHA 2RLOA 3PSCA 3KZ1A 1FHOA 3FSSA 2NZ8B 1V5PA 4HHVA 3PVLA 5J3QA 2CODA 4NSWA 2DX1A 3P6AA 4HAUB 3HK0A 2I5FA 5LOPB 1MAIA 2J59M 5CLLB 5J3YA 1UNPA 1MIXA 2M38A 3TO1A 5HE2A 1V61A 5DH9B 1LW3A 2DTCA 3OANA 2JP2A 1FGYA 1NI2A 2L2IA 2HTHB 4B6HA 3D8EA 5HE3A 3U7DA 4H8SA 3CXBB 2P0DA 1PMSA 2CAYA 2COAA 5KQ1A 2MKRA 4F7HA 2VKIA 4F7GA 1U5FA 2ELBA 1BAKA 1UEFA 2GCJA 1X1FA 2LOZA 2D4QA 2Y8FA 2EMTA 2IFSA 1J19A 3P7ZA 2DLWA 1W1DA 1ZM0A 2COCA 3O96A 2D9XA 5C5BB 3ODXA 3KY9A 1B55A 3MDBC 2L1CA 2VSZA 2EMSA 5KQ4A 5C79A 2RNRB 3TCAA 4ZRKA 2D9VA 2LULA 1X05A 1UNRA 3F5RA 3SYXA 1BTKA 2ZPYA 1RJ2A 3KSYA 2P0FA 4C0AA 1H10A 4ZRJA 2CY4A 1QQGA 2I1KA 2D10A 2R09A 1U27A 3PG7A 3SV1A 4KHOA 4HAVB 2DYNA 4IOYX 3PVWA 1FHXA 1M7RA 5JHGA 2Q13A 4EMOA 1MIZB 4HB0B 2DHJA 1IRSA 3VIAA 2YT0A 2Z0PA 2COFA 1J0WA 4YL8A 1Y19B 3PVUA 4KAXB 2YT1A 1P6SA 4IAPA 5LONB 3UZTA 1EVHA 2LYDA 1RRPB 1NU2A 1FB8A 1TJ6A 4CHJA 2RSGA 4A6FB 4A5KA 3ODOA 4TYZA 3VOQA 1XKEA 4EJNA 1V89A 2D9ZA 1DBHA 1MK9B 5JP4A 2CY5A 2GJYA 2E2XA 4F7UP 3WA0A 2MFQA 2PZ1A 4HB4B 2YRYA 1V88A 1ZC4B 4NY0A 2YF0A 1SGHA 2YS1A 2P0HA 4KVGB 1KI1B 4YONA 3AU5A 2GS0A 5DHAB 2DHIA 3PP2A 3V5WA 2XQNM 1W1GA 2QKLA 1WVHA 2KCJA 5CLQB 4WSFA 3GYOA 1U5DA 4KHAA 2K2UA 4A6HA 1BTNA 4A6KA 4CHMA 2DN6A 1OQNA 5D3WA 3IVFA 1K5GB 4Z2MB 2LG1A 3X23A 2DX5A 1U29A 3A8QA 2RVBB 2EJ8A 1N3HA 2HE7A 1WJ1A 1U5GA 1Z87A 4GPTB 4HAXB 2I1JA 1FOEA 4TKNA 1PLSA 4MT7A 1GC7A 2V76A 1PFJA 3F0WA 1W1HA 4HB3B 3QBVB 1XR0B 1U2BA 3SNHA 1OMWA 2YVCA 5GOWB 2MDXA 1OY2A 1NTYA 5KCVA 1DDVA 2UZSA 2ADZA 1M7EA 1TXDA 3BINA 3PEGA 1DDWA 1V5MA 1WJMA 1WG7A 2KGXB 4DX8A 2DA0A 1ISNA 2KUPA 2LOXA 5C6RA 1P3RA 3CIKA 2RUKB 1XCGA 2J0JA 1KZGA 5C5BA 3WYFB 2X18A 1DDMA 2W2XC 1EAZA 4EKUA 4HATB 2D9WA 3PZDA 1GG3A 4XWXA 4HAYB 3D8FA 4DX90 3SO6A 2IYBA 3TFMA 3QWMA 4L6EA 5D3XA 1ZSQA 3KRXA 1X11A 5EFXA 3LJUX 4DBBA 2R0DA 2K00A 4GZUA 1MPHA 2D11A 4GN1A 3RCPA 5FI0A 2UVMA 1WGQA 1X1GA 5DI9B 1MKEA 1Q67A 4P7IA 1H4RA 1E5WA 3U8ZA 4MK0A 5JLJB 2EC1A 1XX0A 4WVFB 1ZC3B 3FEHA 4WJ7A 3HQCA 3DXEA 2BCJA 5FI1A 2M14A 1TQZA 2MWNB 2ELAA 1AWEA 3A8PA 1V5UA 4GMVA 2YSZA 4BBKA 5C16A 1FAOA 1Y5OA 2DKQA 1UNQA 3ULBA 3BJIA 2Y7BA 3FM8C 3M1IB 4A6FA 4Y94A 4ZRIA 3QIJA 1EGXA 1K5DB 3T06A 1KZ7A 2D9YA 3AU4A 2AL6A 2I5CA 4HDOA 2RGNB 2Y8GA 1FHWA 3GYPA 3TVVA 3ZDTA 4PNKA 1LB1A 5DIFB 5JHHA 4HAZB 1QC6A 4Z2NA 2VRWB 1SHCA 2P8VA 1UPRA 2DYQA 2J0MA 2Z0OA 3ML4A 4K2PA 1XD4A
chains in the Genus database with same CATH superfamily
3DXDA 4HAWB 1DROA 4HB2B 3D8DA 2ROZB 3MPXA 4MY6A 5L81A 5J3TA 2G35A 5HE0A 3SUZA 1P5TA 2KIGA 4GXBA 2H7DA 4KHBB 4PQ0A 2W2WA 2J0KA 3U12A 1BWNA 2NMBA 2DFKA 2YT2A 2Z0QA 1AQCA 4K2OA 1ZVRA 4CSQA 3ZVRA 1U5EA 2K2JA 3KRWA 2FJUB 5D27A 2N23A 4K17A 2LKOA 1DYNA 1NTVA 2UZRA 4GMXB 4K81A 2QKMA 1ZYIA 2CRFA 2YS3A 1UPQA 3DXCA 4IFSA 2H7EA 4CYEA 4HDQA 2YS5A 1MK7B 3ODWA 4DXAB 3A98B 3ULCA 2D2QA 3TW1A 1XODA 2Z4DA 4D0NB 3N7CA 2FJLA 4QJ5B 1EF1A 1I7AA 2ROVA 5DHFB 4QJ4B 1FGZA 2W2XD 3HW2B 3AJ4A 1GC6A 2DKPA 1WGUA 4GNKB 1WI1A 3G9WA 1I2HA 2DHKA 2N0YA 5D3VA 1X86A 5HE1A 3NSUA 2GCLA 5D3YA 2OTXA 2OQBA 2AEHA 2RLOA 3PSCA 3KZ1A 1FHOA 3FSSA 2NZ8B 1V5PA 4HHVA 3PVLA 5J3QA 2CODA 3B77A 4NSWA 2DX1A 3P6AA 4HAUB 3HK0A 2I5FA 5LOPB 1MAIA 2J59M 2Z59A 5CLLB 5J3YA 1T77A 1MIXA 1UNPA 2M38A 3TO1A 5HE2A 1V61A 5DH9B 1LW3A 2DTCA 3OANA 2JP2A 1FGYA 1NI2A 2L2IA 2HTHB 4B6HA 3D8EA 1MI1A 5HE3A 3U7DA 4H8SA 3CXBB 2KR0A 2P0DA 1PMSA 2CAYA 2COAA 5KQ1A 2MKRA 4F7HA 2VKIA 4F7GA 1U5FA 2ELBA 1BAKA 1UEFA 2GCJA 1X1FA 2LOZA 2D4QA 2Y8FA 2EMTA 2IFSA 1J19A 3P7ZA 2DLWA 1W1DA 1ZM0A 2COCA 3O96A 2D9XA 5C5BB 3ODXA 3KY9A 1B55A 3MDBC 2L1CA 2VSZA 4GOUA 2EMSA 5KQ4A 5C79A 2RNRB 3TCAA 4ZRKA 2D9VA 2LULA 1X05A 1UNRA 3F5RA 3SYXA 1BTKA 2ZPYA 2Z13A 1RJ2A 3KSYA 2P0FA 3HSAA 1H10A 4C0AA 4ZRJA 2CY4A 1QQGA 3NW8A 2I1KA 2D10A 2R09A 1U27A 3PG7A 3SV1A 4KHOA 4HAVB 2DYNA 4IOYX 3PVWA 1FHXA 1M7RA 3HIEA 5JHGA 2Q13A 4EMOA 1MIZB 4HB0B 2DHJA 1IRSA 3VIAA 2ZKMX 2YT0A 2Z0PA 2COFA 1J0WA 4YL8A 3A58A 1Y19B 3NWDA 3PVUA 4KAXB 2YT1A 1P6SA 4IAPA 5LONB 3UZTA 1EVHA 2LYDA 4KHBA 3NWFA 1RRPB 1NU2A 1FB8A 1TJ6A 4CHJA 2RSGA 4A6FB 4A5KA 3ODOA 4TYZA 3VOQA 1XKEA 4EJNA 1V89A 2D9ZA 1DBHA 4DIXA 1MK9B 5JP4A 2CY5A 2GJYA 2Z14A 2E2XA 4F7UP 3WA0A 2MFQA 2PZ1A 4HB4B 2YRYA 1V88A 1ZC4B 4NY0A 2YF0A 1SGHA 2YS1A 2P0HA 4KVGB 1KI1B 4YONA 3AU5A 2GS0A 5DHAB 2DHIA 3PP2A 3V5WA 2XQNM 1W1GA 2QKLA 1WVHA 2KCJA 5CLQB 4WSFA 3GYOA 3OHMB 1U5DA 4KHAA 4D6WA 2K2UA 4A6HA 1BTNA 4A6KA 4CHMA 2R2YA 2DN6A 1OQNA 5D3WA 3IVFA 1K5GB 4Z2MB 2LG1A 3X23A 2DX5A 1U29A 3A8QA 2RVBB 2EJ8A 1N3HA 2HE7A 1WJ1A 1U5GA 1Z87A 4GPTB 4HAXB 2I1JA 4QJ3B 1FOEA 4TKNA 1PLSA 4MT7A 2NBVA 1GC7A 2V76A 1PFJA 3F0WA 5I2MA 4HSIA 1W1HA 4HB3B 3QBVB 5I2SA 1XR0B 1U2BA 3SNHA 1OMWA 2YVCA 5GOWB 2MDXA 1OY2A 1NTYA 5KCVA 1DDVA 2UZSA 2ADZA 1M7EA 1TXDA 2KIEA 3BINA 3PEGA 2K8EA 2KUQA 5IRSA 1DDWA 1V5MA 1WJMA 1WG7A 2KGXB 4DX8A 5LG4B 2DA0A 1ISNA 2KUPA 2LOXA 5C6RA 1P3RA 3CIKA 2RUKB 1XCGA 2J0JA 1KZGA 5C5BA 3WYFB 2X18A 1DDMA 2W2XC 1EAZA 4EKUA 4HATB 2D9WA 3PZDA 2RRFA 1GG3A 2GUMA 4XWXA 5M4YB 4HAYB 3D8FA 4DX90 2K49A 4QXAB 3SO6A 2IYBA 3TFMA 3QWMA 4L6EA 5D3XA 1ZSQA 3KRXA 1X11A 5EFXA 3LJUX 4DBBA 2R0DA 2K00A 4GZUA 1MPHA 2D11A 4GN1A 3RCPA 5FI0A 2UVMA 1WGQA 1X1GA 5DI9B 1MKEA 1Q67A 4P7IA 1H4RA 1E5WA 3U8ZA 4MK0A 5JLJB 2EC1A 1XX0A 4WVFB 1ZC3B 3FEHA 4WJ7A 4OSNA 3HQCA 4L1RA 3DXEA 3NWAA 2BCJA 5FI1A 2M14A 1TQZA 2MWNB 2ELAA 1AWEA 3A8PA 1V5UA 4GMVA 2YSZA 4BBKA 5C16A 1FAOA 1Y5OA 2DKQA 1UNQA 3ULBA 3BJIA 2Y7BA 3FM8C 3M1IB 4A6FA 4Y94A 4ZRIA 3QIJA 1EGXA 1K5DB 3T06A 1KZ7A 2D9YA 3AU4A 2AL6A 2I5CA 4HDOA 2RGNB 2Y8GA 1FHWA 3GYPA 3TVVA 3ZDTA 4PNKA 1LB1A 5DIFB 3FVCA 5JHHA 4HAZB 4OT1A 3DCXA 1QC6A 4Z2NA 2VRWB 1SHCA 2P8VA 1UPRA 2DYQA 2J0MA 2Z0OA 3ML4A 4K2PA 1XD4A
chains in the Genus database with same CATH topology
3DXDA 4HAWB 1DROA 4HB2B 3D8DA 2ROZB 3MPXA 4MY6A 5L81A 5J3TA 2G35A 5HE0A 3SUZA 1P5TA 4GXBA 2H7DA 4KHBB 4PQ0A 2W2WA 2J0KA 1BWNA 2NMBA 2DFKA 2Z0QA 1AQCA 4K2OA 1ZVRA 3ZVRA 1U5EA 2K2JA 3KRWA 5D27A 2N23A 4K17A 2LKOA 1DYNA 1NTVA 2UZRA 4GMXB 4K81A 2QKMA 2CRFA 2YS3A 1UPQA 3DXCA 4IFSA 2H7EA 4CYEA 4HDQA 2YS5A 1MK7B 3ODWA 4DXAB 3A98B 3ULCA 2D2QA 3TW1A 1XODA 4D0NB 3N7CA 2FJLA 1EF1A 1I7AA 2ROVA 5DHFB 1FGZA 2W2XD 3HW2B 3AJ4A 1GC6A 2DKPA 1WGUA 1WI1A 3G9WA 1I2HA 2DHKA 2N0YA 5D3VA 1X86A 5HE1A 3NSUA 2GCLA 5D3YA 2OTXA 2OQBA 2AEHA 2RLOA 3PSCA 3KZ1A 1FHOA 3FSSA 2NZ8B 1V5PA 4HHVA 3PVLA 5J3QA 2CODA 4NSWA 2DX1A 3P6AA 4HAUB 3HK0A 2I5FA 5LOPB 1MAIA 2J59M 5CLLB 5J3YA 1UNPA 1MIXA 2M38A 3TO1A 5HE2A 1V61A 5DH9B 1LW3A 2DTCA 3OANA 2JP2A 1FGYA 1NI2A 2L2IA 2HTHB 4B6HA 3D8EA 5HE3A 3U7DA 4H8SA 3CXBB 2P0DA 1PMSA 2CAYA 2COAA 5KQ1A 2MKRA 4F7HA 2VKIA 4F7GA 1U5FA 2ELBA 1BAKA 1UEFA 2GCJA 1X1FA 2LOZA 2D4QA 2Y8FA 2EMTA 2IFSA 1J19A 3P7ZA 2DLWA 1W1DA 1ZM0A 2COCA 3O96A 2D9XA 5C5BB 3ODXA 3KY9A 1B55A 3MDBC 2L1CA 2VSZA 2EMSA 5KQ4A 5C79A 2RNRB 3TCAA 4ZRKA 2D9VA 2LULA 1X05A 1UNRA 3F5RA 3SYXA 1BTKA 2ZPYA 1RJ2A 3KSYA 2P0FA 4C0AA 1H10A 4ZRJA 2CY4A 1QQGA 2I1KA 2D10A 2R09A 1U27A 3PG7A 3SV1A 4KHOA 4HAVB 2DYNA 4IOYX 3PVWA 1FHXA 1M7RA 5JHGA 2Q13A 4EMOA 1MIZB 4HB0B 2DHJA 1IRSA 3VIAA 2YT0A 2Z0PA 2COFA 1J0WA 4YL8A 1Y19B 3PVUA 4KAXB 2YT1A 1P6SA 4IAPA 5LONB 3UZTA 1EVHA 2LYDA 1RRPB 1NU2A 1FB8A 1TJ6A 4CHJA 2RSGA 4A6FB 4A5KA 3ODOA 4TYZA 3VOQA 1XKEA 4EJNA 1V89A 2D9ZA 1DBHA 1MK9B 5JP4A 2CY5A 2GJYA 2E2XA 4F7UP 3WA0A 2MFQA 2PZ1A 4HB4B 2YRYA 1V88A 1ZC4B 4NY0A 2YF0A 1SGHA 2YS1A 2P0HA 4KVGB 1KI1B 4YONA 3AU5A 2GS0A 5DHAB 2DHIA 3PP2A 3V5WA 2XQNM 1W1GA 2QKLA 1WVHA 2KCJA 5CLQB 4WSFA 3GYOA 1U5DA 4KHAA 2K2UA 4A6HA 1BTNA 4A6KA 4CHMA 2DN6A 1OQNA 5D3WA 3IVFA 1K5GB 4Z2MB 2LG1A 3X23A 2DX5A 1U29A 3A8QA 2RVBB 2EJ8A 1N3HA 2HE7A 1WJ1A 1U5GA 1Z87A 4GPTB 4HAXB 2I1JA 1FOEA 4TKNA 1PLSA 4MT7A 1GC7A 2V76A 1PFJA 3F0WA 1W1HA 4HB3B 3QBVB 1XR0B 1U2BA 3SNHA 1OMWA 2YVCA 5GOWB 2MDXA 1OY2A 1NTYA 5KCVA 1DDVA 2UZSA 2ADZA 1M7EA 1TXDA 3BINA 3PEGA 1DDWA 1V5MA 1WJMA 1WG7A 2KGXB 4DX8A 2DA0A 1ISNA 2KUPA 2LOXA 5C6RA 1P3RA 3CIKA 2RUKB 1XCGA 2J0JA 1KZGA 5C5BA 3WYFB 2X18A 1DDMA 2W2XC 1EAZA 4EKUA 4HATB 2D9WA 3PZDA 1GG3A 4XWXA 4HAYB 3D8FA 4DX90 3SO6A 2IYBA 3TFMA 3QWMA 4L6EA 5D3XA 1ZSQA 3KRXA 1X11A 5EFXA 3LJUX 4DBBA 2R0DA 2K00A 4GZUA 1MPHA 2D11A 4GN1A 3RCPA 5FI0A 2UVMA 1WGQA 1X1GA 5DI9B 1MKEA 1Q67A 4P7IA 1H4RA 1E5WA 3U8ZA 4MK0A 5JLJB 2EC1A 1XX0A 4WVFB 1ZC3B 3FEHA 4WJ7A 3HQCA 3DXEA 2BCJA 5FI1A 2M14A 1TQZA 2MWNB 2ELAA 1AWEA 3A8PA 1V5UA 4GMVA 2YSZA 4BBKA 5C16A 1FAOA 1Y5OA 2DKQA 1UNQA 3ULBA 3BJIA 2Y7BA 3FM8C 3M1IB 4A6FA 4Y94A 4ZRIA 3QIJA 1EGXA 1K5DB 3T06A 1KZ7A 2D9YA 3AU4A 2AL6A 2I5CA 4HDOA 2RGNB 2Y8GA 1FHWA 3GYPA 3TVVA 3ZDTA 4PNKA 1LB1A 5DIFB 5JHHA 4HAZB 1QC6A 4Z2NA 2VRWB 1SHCA 2P8VA 1UPRA 2DYQA 2J0MA 2Z0OA 3ML4A 4K2PA 1XD4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DXD A;  4HAW B;  1DRO A;  4HB2 B;  3D8D A;  2ROZ B;  3MPX A;  4MY6 A;  5L81 A;  5J3T A;  2G35 A;  5HE0 A;  3SUZ A;  1P5T A;  4GXB A;  2H7D A;  4KHB B;  4PQ0 A;  2W2W A;  2J0K A;  1BWN A;  2NMB A;  2DFK A;  2Z0Q A;  1AQC A;  4K2O A;  1ZVR A;  3ZVR A;  1U5E A;  2K2J A;  3KRW A;  5D27 A;  2N23 A;  4K17 A;  2LKO A;  1DYN A;  1NTV A;  2UZR A;  4GMX B;  4K81 A;  2QKM A;  2CRF A;  2YS3 A;  1UPQ A;  3DXC A;  4IFS A;  2H7E A;  4CYE A;  4HDQ A;  2YS5 A;  1MK7 B;  3ODW A;  4DXA B;  3A98 B;  3ULC A;  2D2Q A;  3TW1 A;  1XOD A;  4D0N B;  3N7C A;  2FJL A;  1EF1 A;  1I7A A;  2ROV A;  5DHF B;  1FGZ A;  2W2X D;  3HW2 B;  3AJ4 A;  1GC6 A;  2DKP A;  1WGU A;  1WI1 A;  3G9W A;  1I2H A;  2DHK A;  2N0Y A;  5D3V A;  1X86 A;  5HE1 A;  3NSU A;  2GCL A;  5D3Y A;  2OTX A;  2OQB A;  2AEH A;  2RLO A;  3PSC A;  3KZ1 A;  1FHO A;  3FSS A;  2NZ8 B;  1V5P A;  4HHV A;  3PVL A;  5J3Q A;  2COD A;  4NSW A;  2DX1 A;  3P6A A;  4HAU B;  3HK0 A;  2I5F A;  5LOP B;  1MAI A;  2J59 M;  5CLL B;  5J3Y A;  1UNP A;  1MIX A;  2M38 A;  3TO1 A;  5HE2 A;  1V61 A;  5DH9 B;  1LW3 A;  2DTC A;  3OAN A;  2JP2 A;  1FGY A;  1NI2 A;  2L2I A;  2HTH B;  4B6H A;  3D8E A;  5HE3 A;  3U7D A;  4H8S A;  3CXB B;  2P0D A;  1PMS A;  2CAY A;  2COA A;  5KQ1 A;  2MKR A;  4F7H A;  2VKI A;  4F7G A;  1U5F A;  2ELB A;  1BAK A;  1UEF A;  2GCJ A;  1X1F A;  2LOZ A;  2D4Q A;  2Y8F A;  2EMT A;  2IFS A;  1J19 A;  3P7Z A;  2DLW A;  1W1D A;  1ZM0 A;  2COC A;  3O96 A;  2D9X A;  5C5B B;  3ODX A;  3KY9 A;  1B55 A;  3MDB C;  2L1C A;  2VSZ A;  2EMS A;  5KQ4 A;  5C79 A;  2RNR B;  3TCA A;  4ZRK A;  2D9V A;  2LUL A;  1X05 A;  1UNR A;  3F5R A;  3SYX A;  1BTK A;  2ZPY A;  1RJ2 A;  3KSY A;  2P0F A;  4C0A A;  1H10 A;  4ZRJ A;  2CY4 A;  1QQG A;  2I1K A;  2D10 A;  2R09 A;  1U27 A;  3PG7 A;  3SV1 A;  4KHO A;  4HAV B;  2DYN A;  4IOY X;  3PVW A;  1FHX A;  1M7R A;  5JHG A;  2Q13 A;  4EMO A;  1MIZ B;  4HB0 B;  2DHJ A;  1IRS A;  3VIA A;  2YT0 A;  2Z0P A;  2COF A;  1J0W A;  4YL8 A;  1Y19 B;  3PVU A;  4KAX B;  2YT1 A;  1P6S A;  4IAP A;  5LON B;  3UZT A;  1EVH A;  2LYD A;  1RRP B;  1NU2 A;  1FB8 A;  1TJ6 A;  4CHJ A;  2RSG A;  4A6F B;  4A5K A;  3ODO A;  4TYZ A;  3VOQ A;  1XKE A;  4EJN A;  1V89 A;  2D9Z A;  1DBH A;  1MK9 B;  5JP4 A;  2CY5 A;  2GJY A;  2E2X A;  4F7U P;  3WA0 A;  2MFQ A;  2PZ1 A;  4HB4 B;  2YRY A;  1V88 A;  1ZC4 B;  4NY0 A;  2YF0 A;  1SGH A;  2YS1 A;  2P0H A;  4KVG B;  1KI1 B;  4YON A;  3AU5 A;  2GS0 A;  5DHA B;  2DHI A;  3PP2 A;  3V5W A;  2XQN M;  1W1G A;  2QKL A;  1WVH A;  2KCJ A;  5CLQ B;  4WSF A;  3GYO A;  1U5D A;  4KHA A;  2K2U A;  4A6H A;  1BTN A;  4A6K A;  4CHM A;  2DN6 A;  1OQN A;  5D3W A;  3IVF A;  1K5G B;  4Z2M B;  2LG1 A;  3X23 A;  2DX5 A;  1U29 A;  3A8Q A;  2RVB B;  2EJ8 A;  1N3H A;  2HE7 A;  1WJ1 A;  1U5G A;  1Z87 A;  4GPT B;  4HAX B;  2I1J A;  1FOE A;  4TKN A;  1PLS A;  4MT7 A;  1GC7 A;  2V76 A;  1PFJ A;  3F0W A;  1W1H A;  4HB3 B;  3QBV B;  1XR0 B;  1U2B A;  3SNH A;  1OMW A;  2YVC A;  5GOW B;  2MDX A;  1OY2 A;  1NTY A;  5KCV A;  1DDV A;  2UZS A;  2ADZ A;  1M7E A;  1TXD A;  3BIN A;  3PEG A;  1DDW A;  1V5M A;  1WJM A;  1WG7 A;  2KGX B;  4DX8 A;  2DA0 A;  1ISN A;  2KUP A;  2LOX A;  5C6R A;  1P3R A;  3CIK A;  2RUK B;  1XCG A;  2J0J A;  1KZG A;  5C5B A;  3WYF B;  2X18 A;  1DDM A;  2W2X C;  1EAZ A;  4EKU A;  4HAT B;  2D9W A;  3PZD A;  1GG3 A;  4XWX A;  4HAY B;  3D8F A;  4DX9 0;  3SO6 A;  2IYB A;  3TFM A;  3QWM A;  4L6E A;  5D3X A;  1ZSQ A;  3KRX A;  1X11 A;  5EFX A;  3LJU X;  4DBB A;  2R0D A;  2K00 A;  4GZU A;  1MPH A;  2D11 A;  4GN1 A;  3RCP A;  5FI0 A;  2UVM A;  1WGQ A;  1X1G A;  5DI9 B;  1MKE A;  1Q67 A;  4P7I A;  1H4R A;  1E5W A;  3U8Z A;  4MK0 A;  5JLJ B;  2EC1 A;  1XX0 A;  4WVF B;  1ZC3 B;  3FEH A;  4WJ7 A;  3HQC A;  3DXE A;  2BCJ A;  5FI1 A;  2M14 A;  1TQZ A;  2MWN B;  2ELA A;  1AWE A;  3A8P A;  1V5U A;  4GMV A;  2YSZ A;  4BBK A;  5C16 A;  1FAO A;  1Y5O A;  2DKQ A;  1UNQ A;  3ULB A;  3BJI A;  2Y7B A;  3FM8 C;  3M1I B;  4A6F A;  4Y94 A;  4ZRI A;  3QIJ A;  1EGX A;  1K5D B;  3T06 A;  1KZ7 A;  2D9Y A;  3AU4 A;  2AL6 A;  2I5C A;  4HDO A;  2RGN B;  2Y8G A;  1FHW A;  3GYP A;  3TVV A;  3ZDT A;  4PNK A;  1LB1 A;  5DIF B;  5JHH A;  4HAZ B;  1QC6 A;  4Z2N A;  2VRW B;  1SHC A;  2P8V A;  1UPR A;  2DYQ A;  2J0M A;  2Z0O A;  3ML4 A;  4K2P A;  1XD4 A; 
#chains in the Genus database with same CATH topology
 3DXD A;  4HAW B;  1DRO A;  4HB2 B;  3D8D A;  2ROZ B;  3MPX A;  4MY6 A;  5L81 A;  5J3T A;  2G35 A;  5HE0 A;  3SUZ A;  1P5T A;  2KIG A;  4GXB A;  2H7D A;  4KHB B;  4PQ0 A;  2W2W A;  2J0K A;  3U12 A;  1BWN A;  2NMB A;  2DFK A;  2YT2 A;  2Z0Q A;  1AQC A;  4K2O A;  1ZVR A;  4CSQ A;  3ZVR A;  1U5E A;  2K2J A;  3KRW A;  2FJU B;  5D27 A;  2N23 A;  4K17 A;  2LKO A;  1DYN A;  1NTV A;  2UZR A;  4GMX B;  4K81 A;  2QKM A;  1ZYI A;  2CRF A;  2YS3 A;  1UPQ A;  3DXC A;  4IFS A;  2H7E A;  4CYE A;  4HDQ A;  2YS5 A;  1MK7 B;  3ODW A;  4DXA B;  3A98 B;  3ULC A;  2D2Q A;  3TW1 A;  1XOD A;  2Z4D A;  4D0N B;  3N7C A;  2FJL A;  4QJ5 B;  1EF1 A;  1I7A A;  2ROV A;  5DHF B;  4QJ4 B;  1FGZ A;  2W2X D;  3HW2 B;  3AJ4 A;  1GC6 A;  2DKP A;  1WGU A;  4GNK B;  1WI1 A;  3G9W A;  1I2H A;  2DHK A;  2N0Y A;  5D3V A;  1X86 A;  5HE1 A;  3NSU A;  2GCL A;  5D3Y A;  2OTX A;  2OQB A;  2AEH A;  2RLO A;  3PSC A;  3KZ1 A;  1FHO A;  3FSS A;  2NZ8 B;  1V5P A;  4HHV A;  3PVL A;  5J3Q A;  2COD A;  3B77 A;  4NSW A;  2DX1 A;  3P6A A;  4HAU B;  3HK0 A;  2I5F A;  5LOP B;  1MAI A;  2J59 M;  2Z59 A;  5CLL B;  5J3Y A;  1T77 A;  1MIX A;  1UNP A;  2M38 A;  3TO1 A;  5HE2 A;  1V61 A;  5DH9 B;  1LW3 A;  2DTC A;  3OAN A;  2JP2 A;  1FGY A;  1NI2 A;  2L2I A;  2HTH B;  4B6H A;  3D8E A;  1MI1 A;  5HE3 A;  3U7D A;  4H8S A;  3CXB B;  2KR0 A;  2P0D A;  1PMS A;  2CAY A;  2COA A;  5KQ1 A;  2MKR A;  4F7H A;  2VKI A;  4F7G A;  1U5F A;  2ELB A;  1BAK A;  1UEF A;  2GCJ A;  1X1F A;  2LOZ A;  2D4Q A;  2Y8F A;  2EMT A;  2IFS A;  1J19 A;  3P7Z A;  2DLW A;  1W1D A;  1ZM0 A;  2COC A;  3O96 A;  2D9X A;  5C5B B;  3ODX A;  3KY9 A;  1B55 A;  3MDB C;  2L1C A;  2VSZ A;  4GOU A;  2EMS A;  5KQ4 A;  5C79 A;  2RNR B;  3TCA A;  4ZRK A;  2D9V A;  2LUL A;  1X05 A;  1UNR A;  3F5R A;  3SYX A;  1BTK A;  2ZPY A;  2Z13 A;  1RJ2 A;  3KSY A;  2P0F A;  3HSA A;  1H10 A;  4C0A A;  4ZRJ A;  2CY4 A;  1QQG A;  3NW8 A;  2I1K A;  2D10 A;  2R09 A;  1U27 A;  3PG7 A;  3SV1 A;  4KHO A;  4HAV B;  2DYN A;  4IOY X;  3PVW A;  1FHX A;  1M7R A;  3HIE A;  5JHG A;  2Q13 A;  4EMO A;  1MIZ B;  4HB0 B;  2DHJ A;  1IRS A;  3VIA A;  2ZKM X;  2YT0 A;  2Z0P A;  2COF A;  1J0W A;  4YL8 A;  3A58 A;  1Y19 B;  3NWD A;  3PVU A;  4KAX B;  2YT1 A;  1P6S A;  4IAP A;  5LON B;  3UZT A;  1EVH A;  2LYD A;  4KHB A;  3NWF A;  1RRP B;  1NU2 A;  1FB8 A;  1TJ6 A;  4CHJ A;  2RSG A;  4A6F B;  4A5K A;  3ODO A;  4TYZ A;  3VOQ A;  1XKE A;  4EJN A;  1V89 A;  2D9Z A;  1DBH A;  4DIX A;  1MK9 B;  5JP4 A;  2CY5 A;  2GJY A;  2Z14 A;  2E2X A;  4F7U P;  3WA0 A;  2MFQ A;  2PZ1 A;  4HB4 B;  2YRY A;  1V88 A;  1ZC4 B;  4NY0 A;  2YF0 A;  1SGH A;  2YS1 A;  2P0H A;  4KVG B;  1KI1 B;  4YON A;  3AU5 A;  2GS0 A;  5DHA B;  2DHI A;  3PP2 A;  3V5W A;  2XQN M;  1W1G A;  2QKL A;  1WVH A;  2KCJ A;  5CLQ B;  4WSF A;  3GYO A;  3OHM B;  1U5D A;  4KHA A;  4D6W A;  2K2U A;  4A6H A;  1BTN A;  4A6K A;  4CHM A;  2R2Y A;  2DN6 A;  1OQN A;  5D3W A;  3IVF A;  1K5G B;  4Z2M B;  2LG1 A;  3X23 A;  2DX5 A;  1U29 A;  3A8Q A;  2RVB B;  2EJ8 A;  1N3H A;  2HE7 A;  1WJ1 A;  1U5G A;  1Z87 A;  4GPT B;  4HAX B;  2I1J A;  4QJ3 B;  1FOE A;  4TKN A;  1PLS A;  4MT7 A;  2NBV A;  1GC7 A;  2V76 A;  1PFJ A;  3F0W A;  5I2M A;  4HSI A;  1W1H A;  4HB3 B;  3QBV B;  5I2S A;  1XR0 B;  1U2B A;  3SNH A;  1OMW A;  2YVC A;  5GOW B;  2MDX A;  1OY2 A;  1NTY A;  5KCV A;  1DDV A;  2UZS A;  2ADZ A;  1M7E A;  1TXD A;  2KIE A;  3BIN A;  3PEG A;  2K8E A;  2KUQ A;  5IRS A;  1DDW A;  1V5M A;  1WJM A;  1WG7 A;  2KGX B;  4DX8 A;  5LG4 B;  2DA0 A;  1ISN A;  2KUP A;  2LOX A;  5C6R A;  1P3R A;  3CIK A;  2RUK B;  1XCG A;  2J0J A;  1KZG A;  5C5B A;  3WYF B;  2X18 A;  1DDM A;  2W2X C;  1EAZ A;  4EKU A;  4HAT B;  2D9W A;  3PZD A;  2RRF A;  1GG3 A;  2GUM A;  4XWX A;  5M4Y B;  4HAY B;  3D8F A;  4DX9 0;  2K49 A;  4QXA B;  3SO6 A;  2IYB A;  3TFM A;  3QWM A;  4L6E A;  5D3X A;  1ZSQ A;  3KRX A;  1X11 A;  5EFX A;  3LJU X;  4DBB A;  2R0D A;  2K00 A;  4GZU A;  1MPH A;  2D11 A;  4GN1 A;  3RCP A;  5FI0 A;  2UVM A;  1WGQ A;  1X1G A;  5DI9 B;  1MKE A;  1Q67 A;  4P7I A;  1H4R A;  1E5W A;  3U8Z A;  4MK0 A;  5JLJ B;  2EC1 A;  1XX0 A;  4WVF B;  1ZC3 B;  3FEH A;  4WJ7 A;  4OSN A;  3HQC A;  4L1R A;  3DXE A;  3NWA A;  2BCJ A;  5FI1 A;  2M14 A;  1TQZ A;  2MWN B;  2ELA A;  1AWE A;  3A8P A;  1V5U A;  4GMV A;  2YSZ A;  4BBK A;  5C16 A;  1FAO A;  1Y5O A;  2DKQ A;  1UNQ A;  3ULB A;  3BJI A;  2Y7B A;  3FM8 C;  3M1I B;  4A6F A;  4Y94 A;  4ZRI A;  3QIJ A;  1EGX A;  1K5D B;  3T06 A;  1KZ7 A;  2D9Y A;  3AU4 A;  2AL6 A;  2I5C A;  4HDO A;  2RGN B;  2Y8G A;  1FHW A;  3GYP A;  3TVV A;  3ZDT A;  4PNK A;  1LB1 A;  5DIF B;  3FVC A;  5JHH A;  4HAZ B;  4OT1 A;  3DCX A;  1QC6 A;  4Z2N A;  2VRW B;  1SHC A;  2P8V A;  1UPR A;  2DYQ A;  2J0M A;  2Z0O A;  3ML4 A;  4K2P A;  1XD4 A; 
#chains in the Genus database with same CATH homology
 3DXD A;  4HAW B;  1DRO A;  4HB2 B;  3D8D A;  2ROZ B;  3MPX A;  4MY6 A;  5L81 A;  5J3T A;  2G35 A;  5HE0 A;  3SUZ A;  1P5T A;  4GXB A;  2H7D A;  4KHB B;  4PQ0 A;  2W2W A;  2J0K A;  1BWN A;  2NMB A;  2DFK A;  2Z0Q A;  1AQC A;  4K2O A;  1ZVR A;  3ZVR A;  1U5E A;  2K2J A;  3KRW A;  5D27 A;  2N23 A;  4K17 A;  2LKO A;  1DYN A;  1NTV A;  2UZR A;  4GMX B;  4K81 A;  2QKM A;  2CRF A;  2YS3 A;  1UPQ A;  3DXC A;  4IFS A;  2H7E A;  4CYE A;  4HDQ A;  2YS5 A;  1MK7 B;  3ODW A;  4DXA B;  3A98 B;  3ULC A;  2D2Q A;  3TW1 A;  1XOD A;  4D0N B;  3N7C A;  2FJL A;  1EF1 A;  1I7A A;  2ROV A;  5DHF B;  1FGZ A;  2W2X D;  3HW2 B;  3AJ4 A;  1GC6 A;  2DKP A;  1WGU A;  1WI1 A;  3G9W A;  1I2H A;  2DHK A;  2N0Y A;  5D3V A;  1X86 A;  5HE1 A;  3NSU A;  2GCL A;  5D3Y A;  2OTX A;  2OQB A;  2AEH A;  2RLO A;  3PSC A;  3KZ1 A;  1FHO A;  3FSS A;  2NZ8 B;  1V5P A;  4HHV A;  3PVL A;  5J3Q A;  2COD A;  4NSW A;  2DX1 A;  3P6A A;  4HAU B;  3HK0 A;  2I5F A;  5LOP B;  1MAI A;  2J59 M;  5CLL B;  5J3Y A;  1UNP A;  1MIX A;  2M38 A;  3TO1 A;  5HE2 A;  1V61 A;  5DH9 B;  1LW3 A;  2DTC A;  3OAN A;  2JP2 A;  1FGY A;  1NI2 A;  2L2I A;  2HTH B;  4B6H A;  3D8E A;  5HE3 A;  3U7D A;  4H8S A;  3CXB B;  2P0D A;  1PMS A;  2CAY A;  2COA A;  5KQ1 A;  2MKR A;  4F7H A;  2VKI A;  4F7G A;  1U5F A;  2ELB A;  1BAK A;  1UEF A;  2GCJ A;  1X1F A;  2LOZ A;  2D4Q A;  2Y8F A;  2EMT A;  2IFS A;  1J19 A;  3P7Z A;  2DLW A;  1W1D A;  1ZM0 A;  2COC A;  3O96 A;  2D9X A;  5C5B B;  3ODX A;  3KY9 A;  1B55 A;  3MDB C;  2L1C A;  2VSZ A;  2EMS A;  5KQ4 A;  5C79 A;  2RNR B;  3TCA A;  4ZRK A;  2D9V A;  2LUL A;  1X05 A;  1UNR A;  3F5R A;  3SYX A;  1BTK A;  2ZPY A;  1RJ2 A;  3KSY A;  2P0F A;  4C0A A;  1H10 A;  4ZRJ A;  2CY4 A;  1QQG A;  2I1K A;  2D10 A;  2R09 A;  1U27 A;  3PG7 A;  3SV1 A;  4KHO A;  4HAV B;  2DYN A;  4IOY X;  3PVW A;  1FHX A;  1M7R A;  5JHG A;  2Q13 A;  4EMO A;  1MIZ B;  4HB0 B;  2DHJ A;  1IRS A;  3VIA A;  2YT0 A;  2Z0P A;  2COF A;  1J0W A;  4YL8 A;  1Y19 B;  3PVU A;  4KAX B;  2YT1 A;  1P6S A;  4IAP A;  5LON B;  3UZT A;  1EVH A;  2LYD A;  1RRP B;  1NU2 A;  1FB8 A;  1TJ6 A;  4CHJ A;  2RSG A;  4A6F B;  4A5K A;  3ODO A;  4TYZ A;  3VOQ A;  1XKE A;  4EJN A;  1V89 A;  2D9Z A;  1DBH A;  1MK9 B;  5JP4 A;  2CY5 A;  2GJY A;  2E2X A;  4F7U P;  3WA0 A;  2MFQ A;  2PZ1 A;  4HB4 B;  2YRY A;  1V88 A;  1ZC4 B;  4NY0 A;  2YF0 A;  1SGH A;  2YS1 A;  2P0H A;  4KVG B;  1KI1 B;  4YON A;  3AU5 A;  2GS0 A;  5DHA B;  2DHI A;  3PP2 A;  3V5W A;  2XQN M;  1W1G A;  2QKL A;  1WVH A;  2KCJ A;  5CLQ B;  4WSF A;  3GYO A;  1U5D A;  4KHA A;  2K2U A;  4A6H A;  1BTN A;  4A6K A;  4CHM A;  2DN6 A;  1OQN A;  5D3W A;  3IVF A;  1K5G B;  4Z2M B;  2LG1 A;  3X23 A;  2DX5 A;  1U29 A;  3A8Q A;  2RVB B;  2EJ8 A;  1N3H A;  2HE7 A;  1WJ1 A;  1U5G A;  1Z87 A;  4GPT B;  4HAX B;  2I1J A;  1FOE A;  4TKN A;  1PLS A;  4MT7 A;  1GC7 A;  2V76 A;  1PFJ A;  3F0W A;  1W1H A;  4HB3 B;  3QBV B;  1XR0 B;  1U2B A;  3SNH A;  1OMW A;  2YVC A;  5GOW B;  2MDX A;  1OY2 A;  1NTY A;  5KCV A;  1DDV A;  2UZS A;  2ADZ A;  1M7E A;  1TXD A;  3BIN A;  3PEG A;  1DDW A;  1V5M A;  1WJM A;  1WG7 A;  2KGX B;  4DX8 A;  2DA0 A;  1ISN A;  2KUP A;  2LOX A;  5C6R A;  1P3R A;  3CIK A;  2RUK B;  1XCG A;  2J0J A;  1KZG A;  5C5B A;  3WYF B;  2X18 A;  1DDM A;  2W2X C;  1EAZ A;  4EKU A;  4HAT B;  2D9W A;  3PZD A;  1GG3 A;  4XWX A;  4HAY B;  3D8F A;  4DX9 0;  3SO6 A;  2IYB A;  3TFM A;  3QWM A;  4L6E A;  5D3X A;  1ZSQ A;  3KRX A;  1X11 A;  5EFX A;  3LJU X;  4DBB A;  2R0D A;  2K00 A;  4GZU A;  1MPH A;  2D11 A;  4GN1 A;  3RCP A;  5FI0 A;  2UVM A;  1WGQ A;  1X1G A;  5DI9 B;  1MKE A;  1Q67 A;  4P7I A;  1H4R A;  1E5W A;  3U8Z A;  4MK0 A;  5JLJ B;  2EC1 A;  1XX0 A;  4WVF B;  1ZC3 B;  3FEH A;  4WJ7 A;  3HQC A;  3DXE A;  2BCJ A;  5FI1 A;  2M14 A;  1TQZ A;  2MWN B;  2ELA A;  1AWE A;  3A8P A;  1V5U A;  4GMV A;  2YSZ A;  4BBK A;  5C16 A;  1FAO A;  1Y5O A;  2DKQ A;  1UNQ A;  3ULB A;  3BJI A;  2Y7B A;  3FM8 C;  3M1I B;  4A6F A;  4Y94 A;  4ZRI A;  3QIJ A;  1EGX A;  1K5D B;  3T06 A;  1KZ7 A;  2D9Y A;  3AU4 A;  2AL6 A;  2I5C A;  4HDO A;  2RGN B;  2Y8G A;  1FHW A;  3GYP A;  3TVV A;  3ZDT A;  4PNK A;  1LB1 A;  5DIF B;  5JHH A;  4HAZ B;  1QC6 A;  4Z2N A;  2VRW B;  1SHC A;  2P8V A;  1UPR A;  2DYQ A;  2J0M A;  2Z0O A;  3ML4 A;  4K2P A;  1XD4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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