1URBA

Alkaline phosphatase (n51mg)
Total Genus 163
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
Knots found
sequence length
446
structure length
446
Chain Sequence
MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGNGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Alkaline phosphatase
molecule keywords ALKALINE PHOSPHATASE
total genus 163
structure length 446
sequence length 446
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1996-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1urbA00
5LQQA 4GTXA 3WAXA 1ALJA 4NWXA 4LRFA 2IUCB 3BDGA 4GTYA 1E2SP 3M7VA 3T00A 1AJCA 3MK1A 4UOPA 5EGHA 4UPIA 1E33P 1Y7AA 2W5TA 5HRTA 5L0EA 4LRAA 1N2KA 5LRNA 4CYRA 3UO0A 2XRGA 1KHJA 2GSUA 2IUCA 3BDGB 3BDHA 4ZGAA 1KH5A 3WAWA 1ELXA 2W8DA 3DYCA 2W5SA 3NVLA 3B5QA 4CXSA 4CXKA 2QZUA 4TN0A 1ZEDA 1KH4A 2W5VA 5LIAA 1HQAA 5INHA 3SZZA 4FDJA 3NKRA 1ED8A 3M8WA 4MHXA 4KAYA 4CXUA 1ZEFA 4MIVA 5K4PA 4UOOA 1KH7A 5EGEA 3Q3QA 4ZG7A 4UPKA 1HJKA 1EW2A 2GSNA 3OT9A 3TX0A 4B56A 1EW9A 3M8ZA 5DLWA 1SHNA 1ELZA 4YR1A 3UN5A 3MK2A 5AJ9A 1ANIA 3E2DA 5C66A 2GSOA 2W5RA 3UN2A 3A52A 3BDFA 4MY4A 4UPLA 3MK0A 3UNYA 1KHLA 1ALKA 3M8YA 4LRBA 5IJQA 5IJSA 2W5XA 1KH9A 1KHNA 4UPHA 3KD8A 2W5WA 2ZKTA 1EQJA 2W5QA 4KAVA 4QAXA 5KXAA 1O98A 4GTWA 4ZG6A 2GA3A 4LR8A 1EJJA 2GLQA 5LRMA 1SHQA 2IFYA 1B8JA 4KJGA 1Y6VA 4LREA 5GOVA 4ZG9A 3NKQA 1ELYA 1EI6A 1AUKA 2G9YA 2D1GA 3IDDA 4LR9A 1AJDA 1AJBA 1FSUA 3CMRA 2ANHA 1ALHA 3NKMA 2W8SA 4GTZA 1ALIA 3NKNA 1URAA 4LR7A 2XR9A 3WAYA 3UN3A 2VQRA 1ED9A 4FDIA 3WBHA 5TJ3A 1ZEBA 3TWZA 1KHKA 1ANJA 3T01A 3IGYB 3LXQA 4CYSA 1N2LA 1EW8A 4KM4A 5DLTA 3WAVA 3DPCA 3SZYA 5L0KA 5DLVA 3NKPA 1E3CP 2RH6A 3NKOA 4KJDA 4UORA 3TG0A 5L0BA 1O99A 1E1ZP 1K7HA 4N7TA 5GRRA 4LR2A 4LRCA 2X98A 1URBA 3IGZB 3T02A 3ED4A 4NWJA 4LQYA 4LRDA 1AJAA 1HDHA 1P49A
chains in the Genus database with same CATH superfamily
5LQQA 4GTXA 3WAXA 1ALJA 4NWXA 4LRFA 2IUCB 3BDGA 4GTYA 1E2SP 3M7VA 3T00A 1AJCA 3MK1A 4UOPA 5EGHA 4UPIA 1E33P 1Y7AA 2W5TA 5HRTA 5L0EA 4LRAA 1N2KA 5LRNA 4CYRA 3UO0A 2XRGA 1KHJA 2GSUA 2IUCA 3BDGB 3BDHA 4ZGAA 1KH5A 3WAWA 1ELXA 2W8DA 3DYCA 2W5SA 3NVLA 3B5QA 4CXSA 4CXKA 2QZUA 4TN0A 1ZEDA 1KH4A 2W5VA 5LIAA 1HQAA 5INHA 3SZZA 4FDJA 3NKRA 1ED8A 3M8WA 4MHXA 4KAYA 4CXUA 1ZEFA 4MIVA 5K4PA 4UOOA 1KH7A 5EGEA 3Q3QA 4ZG7A 4UPKA 1HJKA 1EW2A 2GSNA 3OT9A 3TX0A 4B56A 1EW9A 3M8ZA 5DLWA 1SHNA 1ELZA 4YR1A 3UN5A 3MK2A 5AJ9A 1ANIA 3E2DA 5C66A 2GSOA 2W5RA 3UN2A 3A52A 3BDFA 4MY4A 4UPLA 3MK0A 3UNYA 1KHLA 1ALKA 3M8YA 4LRBA 5IJQA 5IJSA 2W5XA 1KH9A 1KHNA 4UPHA 3KD8A 2W5WA 2ZKTA 1EQJA 2W5QA 4KAVA 4QAXA 5KXAA 1O98A 4GTWA 4ZG6A 2GA3A 4LR8A 1EJJA 2GLQA 5LRMA 1SHQA 2IFYA 1B8JA 4KJGA 1Y6VA 4LREA 5GOVA 4ZG9A 3NKQA 1ELYA 1EI6A 1AUKA 2G9YA 2D1GA 3IDDA 4LR9A 1AJDA 1AJBA 1FSUA 3CMRA 2ANHA 1ALHA 3NKMA 2W8SA 4GTZA 1ALIA 3NKNA 1URAA 4LR7A 2XR9A 3WAYA 3UN3A 2VQRA 1ED9A 4FDIA 3WBHA 5TJ3A 1ZEBA 3TWZA 1KHKA 1ANJA 3T01A 3IGYB 3LXQA 4CYSA 1N2LA 1EW8A 4KM4A 5DLTA 3WAVA 3DPCA 3SZYA 5L0KA 5DLVA 3NKPA 1E3CP 2RH6A 3NKOA 4KJDA 4UORA 3TG0A 5L0BA 1O99A 1E1ZP 1K7HA 4N7TA 5GRRA 4LR2A 4LRCA 2X98A 1URBA 3IGZB 3T02A 3ED4A 4NWJA 4LQYA 4LRDA 1AJAA 1HDHA 1P49A
chains in the Genus database with same CATH topology
5LQQA 4GTXA 3WAXA 1ALJA 4NWXA 4LRFA 2IUCB 3BDGA 4GTYA 1E2SP 3M7VA 3T00A 1AJCA 3MK1A 4UOPA 5EGHA 4UPIA 1E33P 1Y7AA 2W5TA 5HRTA 5L0EA 4LRAA 1N2KA 5LRNA 4CYRA 3UO0A 2XRGA 1KHJA 2GSUA 2IUCA 3BDGB 3BDHA 4ZGAA 1KH5A 3WAWA 1ELXA 2W8DA 3DYCA 2W5SA 3NVLA 3B5QA 4CXSA 4CXKA 2QZUA 4TN0A 1ZEDA 1KH4A 2W5VA 5LIAA 1HQAA 5INHA 3SZZA 4FDJA 3NKRA 1ED8A 3M8WA 4MHXA 4KAYA 4CXUA 1ZEFA 4MIVA 5K4PA 4UOOA 1KH7A 5EGEA 3Q3QA 4ZG7A 4UPKA 1HJKA 1EW2A 2GSNA 3OT9A 3TX0A 4B56A 1EW9A 3M8ZA 5DLWA 1SHNA 1ELZA 4YR1A 3UN5A 3MK2A 5AJ9A 1ANIA 3E2DA 5C66A 2GSOA 2W5RA 3UN2A 3A52A 3BDFA 4MY4A 4UPLA 3MK0A 3UNYA 1KHLA 1ALKA 3M8YA 4LRBA 5IJQA 5IJSA 2W5XA 1KH9A 1KHNA 4UPHA 3KD8A 2W5WA 2ZKTA 1EQJA 2W5QA 4KAVA 4QAXA 5KXAA 1O98A 4GTWA 4ZG6A 2GA3A 4LR8A 1EJJA 2GLQA 5LRMA 1SHQA 2IFYA 1B8JA 4KJGA 1Y6VA 4LREA 5GOVA 4ZG9A 3NKQA 1ELYA 1EI6A 1AUKA 2G9YA 2D1GA 3IDDA 4LR9A 1AJDA 1AJBA 1FSUA 3CMRA 2ANHA 1ALHA 3NKMA 2W8SA 4GTZA 1ALIA 3NKNA 1URAA 4LR7A 2XR9A 3WAYA 3UN3A 2VQRA 1ED9A 4FDIA 3WBHA 5TJ3A 1ZEBA 3TWZA 1KHKA 1ANJA 3T01A 3IGYB 3LXQA 4CYSA 1N2LA 1EW8A 4KM4A 5DLTA 3WAVA 3DPCA 3SZYA 5L0KA 5DLVA 3NKPA 1E3CP 2RH6A 3NKOA 4KJDA 4UORA 3TG0A 5L0BA 1O99A 1E1ZP 1K7HA 4N7TA 5GRRA 4LR2A 4LRCA 2X98A 1URBA 3IGZB 3T02A 3ED4A 4NWJA 4LQYA 4LRDA 1AJAA 1HDHA 1P49A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LQQ A;  4GTX A;  3WAX A;  1ALJ A;  4NWX A;  4LRF A;  2IUC B;  3BDG A;  4GTY A;  1E2S P;  3M7V A;  3T00 A;  1AJC A;  3MK1 A;  4UOP A;  5EGH A;  4UPI A;  1E33 P;  1Y7A A;  2W5T A;  5HRT A;  5L0E A;  4LRA A;  1N2K A;  5LRN A;  4CYR A;  3UO0 A;  2XRG A;  1KHJ A;  2GSU A;  2IUC A;  3BDG B;  3BDH A;  4ZGA A;  1KH5 A;  3WAW A;  1ELX A;  2W8D A;  3DYC A;  2W5S A;  3NVL A;  3B5Q A;  4CXS A;  4CXK A;  2QZU A;  4TN0 A;  1ZED A;  1KH4 A;  2W5V A;  5LIA A;  1HQA A;  5INH A;  3SZZ A;  4FDJ A;  3NKR A;  1ED8 A;  3M8W A;  4MHX A;  4KAY A;  4CXU A;  1ZEF A;  4MIV A;  5K4P A;  4UOO A;  1KH7 A;  5EGE A;  3Q3Q A;  4ZG7 A;  4UPK A;  1HJK A;  1EW2 A;  2GSN A;  3OT9 A;  3TX0 A;  4B56 A;  1EW9 A;  3M8Z A;  5DLW A;  1SHN A;  1ELZ A;  4YR1 A;  3UN5 A;  3MK2 A;  5AJ9 A;  1ANI A;  3E2D A;  5C66 A;  2GSO A;  2W5R A;  3UN2 A;  3A52 A;  3BDF A;  4MY4 A;  4UPL A;  3MK0 A;  3UNY A;  1KHL A;  1ALK A;  3M8Y A;  4LRB A;  5IJQ A;  5IJS A;  2W5X A;  1KH9 A;  1KHN A;  4UPH A;  3KD8 A;  2W5W A;  2ZKT A;  1EQJ A;  2W5Q A;  4KAV A;  4QAX A;  5KXA A;  1O98 A;  4GTW A;  4ZG6 A;  2GA3 A;  4LR8 A;  1EJJ A;  2GLQ A;  5LRM A;  1SHQ A;  2IFY A;  1B8J A;  4KJG A;  1Y6V A;  4LRE A;  5GOV A;  4ZG9 A;  3NKQ A;  1ELY A;  1EI6 A;  1AUK A;  2G9Y A;  2D1G A;  3IDD A;  4LR9 A;  1AJD A;  1AJB A;  1FSU A;  3CMR A;  2ANH A;  1ALH A;  3NKM A;  2W8S A;  4GTZ A;  1ALI A;  3NKN A;  1URA A;  4LR7 A;  2XR9 A;  3WAY A;  3UN3 A;  2VQR A;  1ED9 A;  4FDI A;  3WBH A;  5TJ3 A;  1ZEB A;  3TWZ A;  1KHK A;  1ANJ A;  3T01 A;  3IGY B;  3LXQ A;  4CYS A;  1N2L A;  1EW8 A;  4KM4 A;  5DLT A;  3WAV A;  3DPC A;  3SZY A;  5L0K A;  5DLV A;  3NKP A;  1E3C P;  2RH6 A;  3NKO A;  4KJD A;  4UOR A;  3TG0 A;  5L0B A;  1O99 A;  1E1Z P;  1K7H A;  4N7T A;  5GRR A;  4LR2 A;  4LRC A;  2X98 A;  1URB A;  3IGZ B;  3T02 A;  3ED4 A;  4NWJ A;  4LQY A;  4LRD A;  1AJA A;  1HDH A;  1P49 A; 
#chains in the Genus database with same CATH topology
 5LQQ A;  4GTX A;  3WAX A;  1ALJ A;  4NWX A;  4LRF A;  2IUC B;  3BDG A;  4GTY A;  1E2S P;  3M7V A;  3T00 A;  1AJC A;  3MK1 A;  4UOP A;  5EGH A;  4UPI A;  1E33 P;  1Y7A A;  2W5T A;  5HRT A;  5L0E A;  4LRA A;  1N2K A;  5LRN A;  4CYR A;  3UO0 A;  2XRG A;  1KHJ A;  2GSU A;  2IUC A;  3BDG B;  3BDH A;  4ZGA A;  1KH5 A;  3WAW A;  1ELX A;  2W8D A;  3DYC A;  2W5S A;  3NVL A;  3B5Q A;  4CXS A;  4CXK A;  2QZU A;  4TN0 A;  1ZED A;  1KH4 A;  2W5V A;  5LIA A;  1HQA A;  5INH A;  3SZZ A;  4FDJ A;  3NKR A;  1ED8 A;  3M8W A;  4MHX A;  4KAY A;  4CXU A;  1ZEF A;  4MIV A;  5K4P A;  4UOO A;  1KH7 A;  5EGE A;  3Q3Q A;  4ZG7 A;  4UPK A;  1HJK A;  1EW2 A;  2GSN A;  3OT9 A;  3TX0 A;  4B56 A;  1EW9 A;  3M8Z A;  5DLW A;  1SHN A;  1ELZ A;  4YR1 A;  3UN5 A;  3MK2 A;  5AJ9 A;  1ANI A;  3E2D A;  5C66 A;  2GSO A;  2W5R A;  3UN2 A;  3A52 A;  3BDF A;  4MY4 A;  4UPL A;  3MK0 A;  3UNY A;  1KHL A;  1ALK A;  3M8Y A;  4LRB A;  5IJQ A;  5IJS A;  2W5X A;  1KH9 A;  1KHN A;  4UPH A;  3KD8 A;  2W5W A;  2ZKT A;  1EQJ A;  2W5Q A;  4KAV A;  4QAX A;  5KXA A;  1O98 A;  4GTW A;  4ZG6 A;  2GA3 A;  4LR8 A;  1EJJ A;  2GLQ A;  5LRM A;  1SHQ A;  2IFY A;  1B8J A;  4KJG A;  1Y6V A;  4LRE A;  5GOV A;  4ZG9 A;  3NKQ A;  1ELY A;  1EI6 A;  1AUK A;  2G9Y A;  2D1G A;  3IDD A;  4LR9 A;  1AJD A;  1AJB A;  1FSU A;  3CMR A;  2ANH A;  1ALH A;  3NKM A;  2W8S A;  4GTZ A;  1ALI A;  3NKN A;  1URA A;  4LR7 A;  2XR9 A;  3WAY A;  3UN3 A;  2VQR A;  1ED9 A;  4FDI A;  3WBH A;  5TJ3 A;  1ZEB A;  3TWZ A;  1KHK A;  1ANJ A;  3T01 A;  3IGY B;  3LXQ A;  4CYS A;  1N2L A;  1EW8 A;  4KM4 A;  5DLT A;  3WAV A;  3DPC A;  3SZY A;  5L0K A;  5DLV A;  3NKP A;  1E3C P;  2RH6 A;  3NKO A;  4KJD A;  4UOR A;  3TG0 A;  5L0B A;  1O99 A;  1E1Z P;  1K7H A;  4N7T A;  5GRR A;  4LR2 A;  4LRC A;  2X98 A;  1URB A;  3IGZ B;  3T02 A;  3ED4 A;  4NWJ A;  4LQY A;  4LRD A;  1AJA A;  1HDH A;  1P49 A; 
#chains in the Genus database with same CATH homology
 5LQQ A;  4GTX A;  3WAX A;  1ALJ A;  4NWX A;  4LRF A;  2IUC B;  3BDG A;  4GTY A;  1E2S P;  3M7V A;  3T00 A;  1AJC A;  3MK1 A;  4UOP A;  5EGH A;  4UPI A;  1E33 P;  1Y7A A;  2W5T A;  5HRT A;  5L0E A;  4LRA A;  1N2K A;  5LRN A;  4CYR A;  3UO0 A;  2XRG A;  1KHJ A;  2GSU A;  2IUC A;  3BDG B;  3BDH A;  4ZGA A;  1KH5 A;  3WAW A;  1ELX A;  2W8D A;  3DYC A;  2W5S A;  3NVL A;  3B5Q A;  4CXS A;  4CXK A;  2QZU A;  4TN0 A;  1ZED A;  1KH4 A;  2W5V A;  5LIA A;  1HQA A;  5INH A;  3SZZ A;  4FDJ A;  3NKR A;  1ED8 A;  3M8W A;  4MHX A;  4KAY A;  4CXU A;  1ZEF A;  4MIV A;  5K4P A;  4UOO A;  1KH7 A;  5EGE A;  3Q3Q A;  4ZG7 A;  4UPK A;  1HJK A;  1EW2 A;  2GSN A;  3OT9 A;  3TX0 A;  4B56 A;  1EW9 A;  3M8Z A;  5DLW A;  1SHN A;  1ELZ A;  4YR1 A;  3UN5 A;  3MK2 A;  5AJ9 A;  1ANI A;  3E2D A;  5C66 A;  2GSO A;  2W5R A;  3UN2 A;  3A52 A;  3BDF A;  4MY4 A;  4UPL A;  3MK0 A;  3UNY A;  1KHL A;  1ALK A;  3M8Y A;  4LRB A;  5IJQ A;  5IJS A;  2W5X A;  1KH9 A;  1KHN A;  4UPH A;  3KD8 A;  2W5W A;  2ZKT A;  1EQJ A;  2W5Q A;  4KAV A;  4QAX A;  5KXA A;  1O98 A;  4GTW A;  4ZG6 A;  2GA3 A;  4LR8 A;  1EJJ A;  2GLQ A;  5LRM A;  1SHQ A;  2IFY A;  1B8J A;  4KJG A;  1Y6V A;  4LRE A;  5GOV A;  4ZG9 A;  3NKQ A;  1ELY A;  1EI6 A;  1AUK A;  2G9Y A;  2D1G A;  3IDD A;  4LR9 A;  1AJD A;  1AJB A;  1FSU A;  3CMR A;  2ANH A;  1ALH A;  3NKM A;  2W8S A;  4GTZ A;  1ALI A;  3NKN A;  1URA A;  4LR7 A;  2XR9 A;  3WAY A;  3UN3 A;  2VQR A;  1ED9 A;  4FDI A;  3WBH A;  5TJ3 A;  1ZEB A;  3TWZ A;  1KHK A;  1ANJ A;  3T01 A;  3IGY B;  3LXQ A;  4CYS A;  1N2L A;  1EW8 A;  4KM4 A;  5DLT A;  3WAV A;  3DPC A;  3SZY A;  5L0K A;  5DLV A;  3NKP A;  1E3C P;  2RH6 A;  3NKO A;  4KJD A;  4UOR A;  3TG0 A;  5L0B A;  1O99 A;  1E1Z P;  1K7H A;  4N7T A;  5GRR A;  4LR2 A;  4LRC A;  2X98 A;  1URB A;  3IGZ B;  3T02 A;  3ED4 A;  4NWJ A;  4LQY A;  4LRD A;  1AJA A;  1HDH A;  1P49 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...