1UW6A

X-ray structure of acetylcholine binding protein (achbp) in complex with nicotine
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
208
structure length
208
Chain Sequence
EFDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in Achbp Crystal Structures
pubmed doi rcsb
molecule tags Glycoprotein
source organism Lymnaea stagnalis
molecule keywords ACETYLCHOLINE-BINDING PROTEIN
total genus 52
structure length 208
sequence length 208
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
ec nomenclature
pdb deposition date 2004-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 1uw6A00
4HFIA 3U8JA 4X5TA 2VL0A 4ZK4A 3EAMA 2PH9A 3TLTA 3C84A 5L4HA 2WNJA 4NPPA 4TWHA 2YN6A 5HCJA 2X00A 2BR7A 4HFCA 5AFKA 2Y56A 2WN9A 3RQWA 2YOEA 3PMZA 3TLVA 2Y7YA 4ZJTA 4TNVA 3T4MA 4IL4A 3IGQA 2XZ6A 4QAAA 2BG9A 4XK9A 4QH5A 5CFBA 3JAFA 2XZ5A 2XNVA 4Z90A 2BG9B 3JAEA 3P50A 4ZR6A 1UW6A 5FJVA 4ILBA 4ZJSA 5AFJA 4UM3P 2XQAA 3EI0A 5JMEA 5AFNA 2YMDA 5HEUA 4EZ1A 4ZZBA 4F8HA 4PIRA 3U8MA 3WTJA 4TNWA 3WIPA 3WTNA 2PGZA 4LMLA 3P4WA 2Y58A 2XQ9A 3ZDHA 4UXUA 3RIAA 4HFEA 3TLWA 5HEHA 2Y54A 4BQTA 4HFHA 3EHZA 2XQ6A 3UU5A 3LSVA 3RIFA 4A98A 2QC1B 1UV6A 3SIOA 4LMKA 5KE4A 4IREA 2UZ6A 3ZDGA 4UY2A 4BFQA 4COFA 4HFBA 1UX2A 5AFMA 5J5HA 4HFDA 3RQUA 2BYSA 2W8FA 3SQ6A 2WNCA 4A97A 5AFMB 5BP0A 2XQ3A 3WTOA 5HCMA 3WTLA 5TVCA 3RI5A 2BYQA 1I9BA 5BW2A 3UQ7A 2BR8A 5HEGA 2WNLA 4D01A 3U8LA 3UQ4A 3ZKRA 4UM1A 2BYPA 3SH1A 3WTMA 5J5FA 5SYOA 2XNUA 4HQPA 4ZZCA 5AFHA 5J5GA 2BG9C 2YKSA 5L47A 5J5IA 3TLUA 5L4EA 2BJ0A 5J0ZA 2XQ7A 2X00D 4DBMA 3SQ9A 3WTHA 3GUAA 4QH1A 5KZUA 5LG3A 3UU3A 3UUBA 2WZYA 4LMJA 4XHEA 3WTKA 2YMEA 3PEOA 4ALXA 4QABA 5CO5A 3U8KA 4QH4A 5LXBA 2Y57A 4ZK1A 5IUXA 3TLSA 5AINA 2XQ4A 4TWDA 4ZRUA 4AFTA 4NZBA 3C79A 4ILAA 4FRRA 2XYSA 4UM3A 4UM3S 2W8GA 3WTIA 3JADA 5BRXA 4QACA 5AFLA 2C9TA 4AFGA 3UU4A 4ILCA 5HEOA 4AFHA 2BYNA 4B5DA 2XNTA 3RHWA 2ZJVA 4IL9A 5HEJA 2ZJUA 2BYRA 3U8NA 2XQ5A 3UU6A 4WV9A 2XYTA 2XQ8A 2BG9E 3UU8A 4TWFA 4Z91A
chains in the Genus database with same CATH superfamily
4HFIA 3U8JA 4X5TA 2VL0A 4ZK4A 3EAMA 2PH9A 3TLTA 3C84A 5L4HA 2WNJA 4NPPA 4TWHA 2YN6A 5HCJA 2X00A 2BR7A 4HFCA 5AFKA 2Y56A 2WN9A 3RQWA 2YOEA 3PMZA 3TLVA 2Y7YA 4ZJTA 4TNVA 3T4MA 4IL4A 3IGQA 2XZ6A 4QAAA 2BG9A 4XK9A 4QH5A 5CFBA 3JAFA 2XZ5A 2XNVA 4Z90A 2BG9B 3JAEA 3P50A 4ZR6A 1UW6A 5FJVA 4ILBA 4ZJSA 5AFJA 4UM3P 2XQAA 3EI0A 5JMEA 5AFNA 2YMDA 5HEUA 4EZ1A 4ZZBA 4F8HA 4PIRA 3U8MA 3WTJA 4TNWA 3WIPA 3WTNA 2PGZA 4LMLA 3P4WA 2Y58A 2XQ9A 3ZDHA 4UXUA 3RIAA 4HFEA 3TLWA 5HEHA 2Y54A 4BQTA 4HFHA 3EHZA 2XQ6A 3UU5A 3LSVA 3RIFA 4A98A 2QC1B 1UV6A 3SIOA 4LMKA 5KE4A 4IREA 2UZ6A 3ZDGA 4UY2A 4BFQA 4COFA 4HFBA 1UX2A 5AFMA 5J5HA 4HFDA 3RQUA 2BYSA 2W8FA 3SQ6A 2WNCA 4A97A 5AFMB 5BP0A 2XQ3A 3WTOA 5HCMA 3WTLA 5TVCA 3RI5A 2BYQA 1I9BA 5BW2A 3UQ7A 2BR8A 5HEGA 2WNLA 4D01A 3U8LA 3UQ4A 3ZKRA 4UM1A 2BYPA 3SH1A 3WTMA 5J5FA 5SYOA 2XNUA 4HQPA 4ZZCA 5AFHA 5J5GA 2BG9C 2YKSA 5L47A 5J5IA 3TLUA 5L4EA 2BJ0A 5J0ZA 2XQ7A 2X00D 4DBMA 3SQ9A 3WTHA 3GUAA 4QH1A 5KZUA 5LG3A 3UU3A 3UUBA 2WZYA 4LMJA 4XHEA 3WTKA 2YMEA 3PEOA 4ALXA 4QABA 5CO5A 3U8KA 4QH4A 5LXBA 2Y57A 4ZK1A 5IUXA 3TLSA 5AINA 2XQ4A 4TWDA 4ZRUA 4AFTA 4NZBA 3C79A 4ILAA 4FRRA 2XYSA 4UM3A 4UM3S 2W8GA 3WTIA 3JADA 5BRXA 4QACA 5AFLA 2C9TA 4AFGA 3UU4A 4ILCA 5HEOA 4AFHA 2BYNA 4B5DA 2XNTA 3RHWA 2ZJVA 4IL9A 5HEJA 2ZJUA 2BYRA 3U8NA 2XQ5A 3UU6A 4WV9A 2XYTA 2XQ8A 2BG9E 3UU8A 4TWFA 4Z91A
chains in the Genus database with same CATH topology
4HFIA 3U8JA 4X5TA 2VL0A 4ZK4A 3EAMA 2PH9A 3TLTA 3C84A 5L4HA 2WNJA 4NPPA 4TWHA 2YN6A 5HCJA 2X00A 2BR7A 4HFCA 5AFKA 2Y56A 2WN9A 3RQWA 2YOEA 3PMZA 3TLVA 2Y7YA 4ZJTA 4TNVA 3T4MA 4IL4A 3IGQA 2XZ6A 4QAAA 2BG9A 4XK9A 4QH5A 5CFBA 3JAFA 2XZ5A 2XNVA 4Z90A 2BG9B 3JAEA 3P50A 4ZR6A 1UW6A 5FJVA 4ILBA 4ZJSA 5AFJA 4UM3P 2XQAA 3EI0A 5JMEA 5AFNA 2YMDA 5HEUA 4EZ1A 4ZZBA 4F8HA 4PIRA 3U8MA 3WTJA 4TNWA 3WIPA 3WTNA 2PGZA 4LMLA 3P4WA 2Y58A 2XQ9A 3ZDHA 4UXUA 3RIAA 4HFEA 3TLWA 5HEHA 2Y54A 4BQTA 4HFHA 3EHZA 2XQ6A 3UU5A 3LSVA 3RIFA 4A98A 2QC1B 1UV6A 3SIOA 4LMKA 5KE4A 4IREA 2UZ6A 3ZDGA 4UY2A 4BFQA 4COFA 4HFBA 1UX2A 5AFMA 5J5HA 4HFDA 3RQUA 2BYSA 2W8FA 3SQ6A 2WNCA 4A97A 5AFMB 5BP0A 2XQ3A 3WTOA 5HCMA 3WTLA 5TVCA 3RI5A 2BYQA 1I9BA 5BW2A 3UQ7A 2BR8A 5HEGA 2WNLA 4D01A 3U8LA 3UQ4A 3ZKRA 4UM1A 2BYPA 3SH1A 3WTMA 5J5FA 5SYOA 2XNUA 4HQPA 4ZZCA 5AFHA 5J5GA 2BG9C 2YKSA 5L47A 5J5IA 3TLUA 5L4EA 2BJ0A 5J0ZA 2XQ7A 2X00D 4DBMA 3SQ9A 3WTHA 3GUAA 4QH1A 5KZUA 5LG3A 3UU3A 3UUBA 2WZYA 4LMJA 4XHEA 3WTKA 2YMEA 3PEOA 4ALXA 4QABA 5CO5A 3U8KA 4QH4A 5LXBA 2Y57A 4ZK1A 5IUXA 3TLSA 5AINA 2XQ4A 4TWDA 4ZRUA 4AFTA 4NZBA 3C79A 4ILAA 4FRRA 2XYSA 4UM3A 4UM3S 2W8GA 3WTIA 3JADA 5BRXA 4QACA 5AFLA 2C9TA 4AFGA 3UU4A 4ILCA 5HEOA 4AFHA 2BYNA 4B5DA 2XNTA 3RHWA 2ZJVA 4IL9A 5HEJA 2ZJUA 2BYRA 3U8NA 2XQ5A 3UU6A 4WV9A 2XYTA 2XQ8A 2BG9E 3UU8A 4TWFA 4Z91A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HFI A;  3U8J A;  4X5T A;  2VL0 A;  4ZK4 A;  3EAM A;  2PH9 A;  3TLT A;  3C84 A;  5L4H A;  2WNJ A;  4NPP A;  4TWH A;  2YN6 A;  5HCJ A;  2X00 A;  2BR7 A;  4HFC A;  5AFK A;  2Y56 A;  2WN9 A;  3RQW A;  2YOE A;  3PMZ A;  3TLV A;  2Y7Y A;  4ZJT A;  4TNV A;  3T4M A;  4IL4 A;  3IGQ A;  2XZ6 A;  4QAA A;  2BG9 A;  4XK9 A;  4QH5 A;  5CFB A;  3JAF A;  2XZ5 A;  2XNV A;  4Z90 A;  2BG9 B;  3JAE A;  3P50 A;  4ZR6 A;  1UW6 A;  5FJV A;  4ILB A;  4ZJS A;  5AFJ A;  4UM3 P;  2XQA A;  3EI0 A;  5JME A;  5AFN A;  2YMD A;  5HEU A;  4EZ1 A;  4ZZB A;  4F8H A;  4PIR A;  3U8M A;  3WTJ A;  4TNW A;  3WIP A;  3WTN A;  2PGZ A;  4LML A;  3P4W A;  2Y58 A;  2XQ9 A;  3ZDH A;  4UXU A;  3RIA A;  4HFE A;  3TLW A;  5HEH A;  2Y54 A;  4BQT A;  4HFH A;  3EHZ A;  2XQ6 A;  3UU5 A;  3LSV A;  3RIF A;  4A98 A;  2QC1 B;  1UV6 A;  3SIO A;  4LMK A;  5KE4 A;  4IRE A;  2UZ6 A;  3ZDG A;  4UY2 A;  4BFQ A;  4COF A;  4HFB A;  1UX2 A;  5AFM A;  5J5H A;  4HFD A;  3RQU A;  2BYS A;  2W8F A;  3SQ6 A;  2WNC A;  4A97 A;  5AFM B;  5BP0 A;  2XQ3 A;  3WTO A;  5HCM A;  3WTL A;  5TVC A;  3RI5 A;  2BYQ A;  1I9B A;  5BW2 A;  3UQ7 A;  2BR8 A;  5HEG A;  2WNL A;  4D01 A;  3U8L A;  3UQ4 A;  3ZKR A;  4UM1 A;  2BYP A;  3SH1 A;  3WTM A;  5J5F A;  5SYO A;  2XNU A;  4HQP A;  4ZZC A;  5AFH A;  5J5G A;  2BG9 C;  2YKS A;  5L47 A;  5J5I A;  3TLU A;  5L4E A;  2BJ0 A;  5J0Z A;  2XQ7 A;  2X00 D;  4DBM A;  3SQ9 A;  3WTH A;  3GUA A;  4QH1 A;  5KZU A;  5LG3 A;  3UU3 A;  3UUB A;  2WZY A;  4LMJ A;  4XHE A;  3WTK A;  2YME A;  3PEO A;  4ALX A;  4QAB A;  5CO5 A;  3U8K A;  4QH4 A;  5LXB A;  2Y57 A;  4ZK1 A;  5IUX A;  3TLS A;  5AIN A;  2XQ4 A;  4TWD A;  4ZRU A;  4AFT A;  4NZB A;  3C79 A;  4ILA A;  4FRR A;  2XYS A;  4UM3 A;  4UM3 S;  2W8G A;  3WTI A;  3JAD A;  5BRX A;  4QAC A;  5AFL A;  2C9T A;  4AFG A;  3UU4 A;  4ILC A;  5HEO A;  4AFH A;  2BYN A;  4B5D A;  2XNT A;  3RHW A;  2ZJV A;  4IL9 A;  5HEJ A;  2ZJU A;  2BYR A;  3U8N A;  2XQ5 A;  3UU6 A;  4WV9 A;  2XYT A;  2XQ8 A;  2BG9 E;  3UU8 A;  4TWF A;  4Z91 A; 
#chains in the Genus database with same CATH topology
 4HFI A;  3U8J A;  4X5T A;  2VL0 A;  4ZK4 A;  3EAM A;  2PH9 A;  3TLT A;  3C84 A;  5L4H A;  2WNJ A;  4NPP A;  4TWH A;  2YN6 A;  5HCJ A;  2X00 A;  2BR7 A;  4HFC A;  5AFK A;  2Y56 A;  2WN9 A;  3RQW A;  2YOE A;  3PMZ A;  3TLV A;  2Y7Y A;  4ZJT A;  4TNV A;  3T4M A;  4IL4 A;  3IGQ A;  2XZ6 A;  4QAA A;  2BG9 A;  4XK9 A;  4QH5 A;  5CFB A;  3JAF A;  2XZ5 A;  2XNV A;  4Z90 A;  2BG9 B;  3JAE A;  3P50 A;  4ZR6 A;  1UW6 A;  5FJV A;  4ILB A;  4ZJS A;  5AFJ A;  4UM3 P;  2XQA A;  3EI0 A;  5JME A;  5AFN A;  2YMD A;  5HEU A;  4EZ1 A;  4ZZB A;  4F8H A;  4PIR A;  3U8M A;  3WTJ A;  4TNW A;  3WIP A;  3WTN A;  2PGZ A;  4LML A;  3P4W A;  2Y58 A;  2XQ9 A;  3ZDH A;  4UXU A;  3RIA A;  4HFE A;  3TLW A;  5HEH A;  2Y54 A;  4BQT A;  4HFH A;  3EHZ A;  2XQ6 A;  3UU5 A;  3LSV A;  3RIF A;  4A98 A;  2QC1 B;  1UV6 A;  3SIO A;  4LMK A;  5KE4 A;  4IRE A;  2UZ6 A;  3ZDG A;  4UY2 A;  4BFQ A;  4COF A;  4HFB A;  1UX2 A;  5AFM A;  5J5H A;  4HFD A;  3RQU A;  2BYS A;  2W8F A;  3SQ6 A;  2WNC A;  4A97 A;  5AFM B;  5BP0 A;  2XQ3 A;  3WTO A;  5HCM A;  3WTL A;  5TVC A;  3RI5 A;  2BYQ A;  1I9B A;  5BW2 A;  3UQ7 A;  2BR8 A;  5HEG A;  2WNL A;  4D01 A;  3U8L A;  3UQ4 A;  3ZKR A;  4UM1 A;  2BYP A;  3SH1 A;  3WTM A;  5J5F A;  5SYO A;  2XNU A;  4HQP A;  4ZZC A;  5AFH A;  5J5G A;  2BG9 C;  2YKS A;  5L47 A;  5J5I A;  3TLU A;  5L4E A;  2BJ0 A;  5J0Z A;  2XQ7 A;  2X00 D;  4DBM A;  3SQ9 A;  3WTH A;  3GUA A;  4QH1 A;  5KZU A;  5LG3 A;  3UU3 A;  3UUB A;  2WZY A;  4LMJ A;  4XHE A;  3WTK A;  2YME A;  3PEO A;  4ALX A;  4QAB A;  5CO5 A;  3U8K A;  4QH4 A;  5LXB A;  2Y57 A;  4ZK1 A;  5IUX A;  3TLS A;  5AIN A;  2XQ4 A;  4TWD A;  4ZRU A;  4AFT A;  4NZB A;  3C79 A;  4ILA A;  4FRR A;  2XYS A;  4UM3 A;  4UM3 S;  2W8G A;  3WTI A;  3JAD A;  5BRX A;  4QAC A;  5AFL A;  2C9T A;  4AFG A;  3UU4 A;  4ILC A;  5HEO A;  4AFH A;  2BYN A;  4B5D A;  2XNT A;  3RHW A;  2ZJV A;  4IL9 A;  5HEJ A;  2ZJU A;  2BYR A;  3U8N A;  2XQ5 A;  3UU6 A;  4WV9 A;  2XYT A;  2XQ8 A;  2BG9 E;  3UU8 A;  4TWF A;  4Z91 A; 
#chains in the Genus database with same CATH homology
 4HFI A;  3U8J A;  4X5T A;  2VL0 A;  4ZK4 A;  3EAM A;  2PH9 A;  3TLT A;  3C84 A;  5L4H A;  2WNJ A;  4NPP A;  4TWH A;  2YN6 A;  5HCJ A;  2X00 A;  2BR7 A;  4HFC A;  5AFK A;  2Y56 A;  2WN9 A;  3RQW A;  2YOE A;  3PMZ A;  3TLV A;  2Y7Y A;  4ZJT A;  4TNV A;  3T4M A;  4IL4 A;  3IGQ A;  2XZ6 A;  4QAA A;  2BG9 A;  4XK9 A;  4QH5 A;  5CFB A;  3JAF A;  2XZ5 A;  2XNV A;  4Z90 A;  2BG9 B;  3JAE A;  3P50 A;  4ZR6 A;  1UW6 A;  5FJV A;  4ILB A;  4ZJS A;  5AFJ A;  4UM3 P;  2XQA A;  3EI0 A;  5JME A;  5AFN A;  2YMD A;  5HEU A;  4EZ1 A;  4ZZB A;  4F8H A;  4PIR A;  3U8M A;  3WTJ A;  4TNW A;  3WIP A;  3WTN A;  2PGZ A;  4LML A;  3P4W A;  2Y58 A;  2XQ9 A;  3ZDH A;  4UXU A;  3RIA A;  4HFE A;  3TLW A;  5HEH A;  2Y54 A;  4BQT A;  4HFH A;  3EHZ A;  2XQ6 A;  3UU5 A;  3LSV A;  3RIF A;  4A98 A;  2QC1 B;  1UV6 A;  3SIO A;  4LMK A;  5KE4 A;  4IRE A;  2UZ6 A;  3ZDG A;  4UY2 A;  4BFQ A;  4COF A;  4HFB A;  1UX2 A;  5AFM A;  5J5H A;  4HFD A;  3RQU A;  2BYS A;  2W8F A;  3SQ6 A;  2WNC A;  4A97 A;  5AFM B;  5BP0 A;  2XQ3 A;  3WTO A;  5HCM A;  3WTL A;  5TVC A;  3RI5 A;  2BYQ A;  1I9B A;  5BW2 A;  3UQ7 A;  2BR8 A;  5HEG A;  2WNL A;  4D01 A;  3U8L A;  3UQ4 A;  3ZKR A;  4UM1 A;  2BYP A;  3SH1 A;  3WTM A;  5J5F A;  5SYO A;  2XNU A;  4HQP A;  4ZZC A;  5AFH A;  5J5G A;  2BG9 C;  2YKS A;  5L47 A;  5J5I A;  3TLU A;  5L4E A;  2BJ0 A;  5J0Z A;  2XQ7 A;  2X00 D;  4DBM A;  3SQ9 A;  3WTH A;  3GUA A;  4QH1 A;  5KZU A;  5LG3 A;  3UU3 A;  3UUB A;  2WZY A;  4LMJ A;  4XHE A;  3WTK A;  2YME A;  3PEO A;  4ALX A;  4QAB A;  5CO5 A;  3U8K A;  4QH4 A;  5LXB A;  2Y57 A;  4ZK1 A;  5IUX A;  3TLS A;  5AIN A;  2XQ4 A;  4TWD A;  4ZRU A;  4AFT A;  4NZB A;  3C79 A;  4ILA A;  4FRR A;  2XYS A;  4UM3 A;  4UM3 S;  2W8G A;  3WTI A;  3JAD A;  5BRX A;  4QAC A;  5AFL A;  2C9T A;  4AFG A;  3UU4 A;  4ILC A;  5HEO A;  4AFH A;  2BYN A;  4B5D A;  2XNT A;  3RHW A;  2ZJV A;  4IL9 A;  5HEJ A;  2ZJU A;  2BYR A;  3U8N A;  2XQ5 A;  3UU6 A;  4WV9 A;  2XYT A;  2XQ8 A;  2BG9 E;  3UU8 A;  4TWF A;  4Z91 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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