1VAOA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
molecule tags Flavoenzyme
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 170
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1vaoA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1vaoA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1vaoA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1vaoA03
2GQUA 1T3QC 3FW9A 1W1RA 3S1DA 3NVZB 1MBTA 3TSHA 5HQXA 3HRDC 4PZFA 1FFVC 3JS8A 4BC7A 5ADZA 1VAOA 1E8GA 1FIQB 4PVHA 5HHZA 3DEDA 4BC9A 2GQTA 3AM9A 4PYTA 2VAOA 5HMRA 3W8XA 1WVFA 2PLSA 1MBBA 3NVYB 3NVVB 1W1JA 2AXRA 1FO4A 1ZR6A 1W1LA 2MBRA 1FFUC 5FXPA 2BVGA 4OALA 2W3SA 2RK5A 4HG0A 3NVWB 2W55A 1E8FA 1W1QA 1SB3B 4BBYA 2O3GA 5D79A 4DNSA 5FXEA 3B9JB 3PM9A 5G5HB 4O95A 1HSKA 4UD8A 1VDVA 3SR6B 4XLOA 2I0KA 4ZOHB 2VFVA 5AE1A 2P3HA 1RM6B 4ML8A 2NQWA 1W1MA 4JB1A 2Q85A 2R2ZA 1QLUA 3FW8A 3AN1A 5FXDA 3I99A 4BCAA 2QKNA 2QPMA 3TX1A 3NS1B 1W1SA 1WYGA 4MLAA 4PVKA 1JRPA 3W8ZA 1ZXIC 3LAEA 1E8HA 1N62C 1E0YA 2P4PA 1W1OA 3S1EA 3W8WA 3BW7A 3FWAA 5G5GB 2EXRA 3S1CA 3AMZA 5AE2A 1N5XA 3GSYA 3VTEA 1JROA 3DQ0A 2PLIA 2W54A 1QLTA 1W1KA 1F0XA 1N5WC 1AHVA 3EUB3 1DIIA 2E3TA 5FXFA 1AHZA 2BVFA 1N63C 3D2DA 1WVEA 1V97A 3FW7A 2VFRA 2VFUA 4PWBA 3LLBA 1DZNA 1N60C 2W3RA 2P13A 2R8DA 3S1FA 2VFTA 4EC3A 2OAIA 2YVSA 3C0PA 1DIQA 1AHUA 3NRZB 3D2JA 2BVHA 3ETRB 3KJMA 3TSJA 1I19A 1N61C 4PWCA 3D2HA 2VFSA 1UXYA 5AE3A 4PVEA 4JAYA 4PVJA 2Q4WA
chains in the Genus database with same CATH superfamily
2GQUA 1T3QC 3FW9A 3RJAA 1W1RA 3S1DA 3NVZB 1MBTA 3TSHA 5HQXA 3HRDC 4PZFA 1FFVC 3JS8A 4BC7A 5ADZA 1VAOA 1E8GA 1FIQB 4PVHA 5HHZA 3DEDA 4BC9A 2GQTA 3AM9A 4PYTA 2VAOA 5HMRA 3W8XA 1WVFA 2PLSA 1MBBA 3NVYB 3NVVB 3EJEB 1W1JA 2WDWA 2AXRA 2Y4GA 1FO4A 1ZR6A 1W1LA 2UUUA 2MBRA 1FFUC 5FXPA 2BVGA 4OALA 2W3SA 2RK5A 4HG0A 3NVWB 2W55A 1E8FA 1W1QA 1SB3B 4BBYA 2O3GA 5D79A 4DNSA 5FXEA 3B9JB 3PM9A 5G5HB 4O95A 1HSKA 4UD8A 2Y3RA 5K8EA 1VDVA 2IPIA 3SR6B 4XLOA 2I0KA 4ZOHB 2VFVA 5AE1A 2P3HA 1RM6B 4ML8A 2NQWA 1W1MA 3RJ8A 4JB1A 2Q85A 2R2ZA 1QLUA 3FW8A 3AN1A 5FXDA 3I99A 4BCAA 2QKNA 2QPMA 3TX1A 3NS1B 1W1SA 1WYGA 4MLAA 4PVKA 1JRPA 3W8ZA 3EJBB 3EJDB 1ZXIC 3PQBA 3LAEA 1E8HA 1N62C 1E0YA 2P4PA 1W1OA 3S1EA 3W8WA 3BW7A 3FWAA 5G5GB 2EXRA 3S1CA 3AMZA 5AE2A 1N5XA 3GSYA 3VTEA 5I1VA 1JROA 3DQ0A 2PLIA 2W54A 5I1WA 1QLTA 1W1KA 1F0XA 1N5WC 5L6FA 2Y3SA 3POPA 1AHVA 3EUB3 5L6GA 1DIIA 2E3TA 5FXFA 1AHZA 2BVFA 1N63C 3D2DA 1WVEA 1V97A 3FW7A 2VFRA 2VFUA 4PWBA 3LLBA 1DZNA 3HSUA 1N60C 2Y08A 2W3RA 2P13A 5AWVA 2R8DA 3S1FA 2VFTA 4EC3A 2OAIA 2YVSA 3C0PA 1DIQA 1AHUA 3NRZB 3D2JA 2BVHA 3ETRB 3KJMA 3TSJA 1I19A 1N61C 4PWCA 3D2HA 2VFSA 1UXYA 2UUVA 5AE3A 4PVEA 4JAYA 4PVJA 2Q4WA
chains in the Genus database with same CATH topology
2GQUA 1T3QC 3FW9A 3RJAA 1W1RA 3S1DA 3NVZB 1MBTA 3TSHA 5HQXA 3HRDC 4PZFA 1FFVC 3JS8A 4BC7A 5ADZA 1VAOA 1E8GA 1FIQB 4PVHA 5HHZA 3DEDA 4BC9A 2GQTA 3AM9A 4PYTA 2VAOA 5HMRA 3W8XA 1WVFA 2PLSA 1MBBA 3NVYB 3NVVB 1W1JA 2WDWA 2AXRA 2Y4GA 1FO4A 1ZR6A 1W1LA 2UUUA 2MBRA 1FFUC 5FXPA 2BVGA 4OALA 2W3SA 2RK5A 4HG0A 3NVWB 2W55A 1E8FA 1W1QA 1SB3B 4BBYA 2O3GA 5D79A 4DNSA 5FXEA 3B9JB 3PM9A 5G5HB 4O95A 1HSKA 4UD8A 2Y3RA 5K8EA 1VDVA 2IPIA 3SR6B 4XLOA 2I0KA 4ZOHB 2VFVA 5AE1A 2P3HA 1RM6B 4ML8A 2NQWA 1W1MA 3RJ8A 4JB1A 2Q85A 2R2ZA 1QLUA 3FW8A 3AN1A 5FXDA 3I99A 4BCAA 2QKNA 2QPMA 3TX1A 3NS1B 1W1SA 1WYGA 4MLAA 4PVKA 1JRPA 3W8ZA 1ZXIC 3PQBA 3LAEA 1E8HA 1N62C 1E0YA 2P4PA 1W1OA 3S1EA 3W8WA 3BW7A 3FWAA 5G5GB 2EXRA 3S1CA 3AMZA 5AE2A 1N5XA 3GSYA 3VTEA 5I1VA 1JROA 3DQ0A 2PLIA 2W54A 5I1WA 1QLTA 1W1KA 1F0XA 1N5WC 5L6FA 2Y3SA 3POPA 1AHVA 3EUB3 5L6GA 1DIIA 2E3TA 5FXFA 1AHZA 2BVFA 1N63C 3D2DA 1WVEA 1V97A 3FW7A 2VFRA 2VFUA 4PWBA 3LLBA 1DZNA 3HSUA 1N60C 2Y08A 2W3RA 2P13A 5AWVA 2R8DA 3S1FA 2VFTA 4EC3A 2OAIA 2YVSA 3C0PA 1DIQA 1AHUA 3NRZB 3D2JA 2BVHA 3ETRB 3KJMA 3TSJA 1I19A 1N61C 4PWCA 3D2HA 2VFSA 1UXYA 2UUVA 5AE3A 4PVEA 4JAYA 4PVJA 2Q4WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GQU A;  1T3Q C;  3FW9 A;  1W1R A;  3S1D A;  3NVZ B;  1MBT A;  3TSH A;  5HQX A;  3HRD C;  4PZF A;  1FFV C;  3JS8 A;  4BC7 A;  5ADZ A;  1VAO A;  1E8G A;  1FIQ B;  4PVH A;  5HHZ A;  3DED A;  4BC9 A;  2GQT A;  3AM9 A;  4PYT A;  2VAO A;  5HMR A;  3W8X A;  1WVF A;  2PLS A;  1MBB A;  3NVY B;  3NVV B;  1W1J A;  2AXR A;  1FO4 A;  1ZR6 A;  1W1L A;  2MBR A;  1FFU C;  5FXP A;  2BVG A;  4OAL A;  2W3S A;  2RK5 A;  4HG0 A;  3NVW B;  2W55 A;  1E8F A;  1W1Q A;  1SB3 B;  4BBY A;  2O3G A;  5D79 A;  4DNS A;  5FXE A;  3B9J B;  3PM9 A;  5G5H B;  4O95 A;  1HSK A;  4UD8 A;  1VDV A;  3SR6 B;  4XLO A;  2I0K A;  4ZOH B;  2VFV A;  5AE1 A;  2P3H A;  1RM6 B;  4ML8 A;  2NQW A;  1W1M A;  4JB1 A;  2Q85 A;  2R2Z A;  1QLU A;  3FW8 A;  3AN1 A;  5FXD A;  3I99 A;  4BCA A;  2QKN A;  2QPM A;  3TX1 A;  3NS1 B;  1W1S A;  1WYG A;  4MLA A;  4PVK A;  1JRP A;  3W8Z A;  1ZXI C;  3LAE A;  1E8H A;  1N62 C;  1E0Y A;  2P4P A;  1W1O A;  3S1E A;  3W8W A;  3BW7 A;  3FWA A;  5G5G B;  2EXR A;  3S1C A;  3AMZ A;  5AE2 A;  1N5X A;  3GSY A;  3VTE A;  1JRO A;  3DQ0 A;  2PLI A;  2W54 A;  1QLT A;  1W1K A;  1F0X A;  1N5W C;  1AHV A;  3EUB 3;  1DII A;  2E3T A;  5FXF A;  1AHZ A;  2BVF A;  1N63 C;  3D2D A;  1WVE A;  1V97 A;  3FW7 A;  2VFR A;  2VFU A;  4PWB A;  3LLB A;  1DZN A;  1N60 C;  2W3R A;  2P13 A;  2R8D A;  3S1F A;  2VFT A;  4EC3 A;  2OAI A;  2YVS A;  3C0P A;  1DIQ A;  1AHU A;  3NRZ B;  3D2J A;  2BVH A;  3ETR B;  3KJM A;  3TSJ A;  1I19 A;  1N61 C;  4PWC A;  3D2H A;  2VFS A;  1UXY A;  5AE3 A;  4PVE A;  4JAY A;  4PVJ A;  2Q4W A; 
#chains in the Genus database with same CATH topology
 2GQU A;  1T3Q C;  3FW9 A;  3RJA A;  1W1R A;  3S1D A;  3NVZ B;  1MBT A;  3TSH A;  5HQX A;  3HRD C;  4PZF A;  1FFV C;  3JS8 A;  4BC7 A;  5ADZ A;  1VAO A;  1E8G A;  1FIQ B;  4PVH A;  5HHZ A;  3DED A;  4BC9 A;  2GQT A;  3AM9 A;  4PYT A;  2VAO A;  5HMR A;  3W8X A;  1WVF A;  2PLS A;  1MBB A;  3NVY B;  3NVV B;  3EJE B;  1W1J A;  2WDW A;  2AXR A;  2Y4G A;  1FO4 A;  1ZR6 A;  1W1L A;  2UUU A;  2MBR A;  1FFU C;  5FXP A;  2BVG A;  4OAL A;  2W3S A;  2RK5 A;  4HG0 A;  3NVW B;  2W55 A;  1E8F A;  1W1Q A;  1SB3 B;  4BBY A;  2O3G A;  5D79 A;  4DNS A;  5FXE A;  3B9J B;  3PM9 A;  5G5H B;  4O95 A;  1HSK A;  4UD8 A;  2Y3R A;  5K8E A;  1VDV A;  2IPI A;  3SR6 B;  4XLO A;  2I0K A;  4ZOH B;  2VFV A;  5AE1 A;  2P3H A;  1RM6 B;  4ML8 A;  2NQW A;  1W1M A;  3RJ8 A;  4JB1 A;  2Q85 A;  2R2Z A;  1QLU A;  3FW8 A;  3AN1 A;  5FXD A;  3I99 A;  4BCA A;  2QKN A;  2QPM A;  3TX1 A;  3NS1 B;  1W1S A;  1WYG A;  4MLA A;  4PVK A;  1JRP A;  3W8Z A;  3EJB B;  3EJD B;  1ZXI C;  3PQB A;  3LAE A;  1E8H A;  1N62 C;  1E0Y A;  2P4P A;  1W1O A;  3S1E A;  3W8W A;  3BW7 A;  3FWA A;  5G5G B;  2EXR A;  3S1C A;  3AMZ A;  5AE2 A;  1N5X A;  3GSY A;  3VTE A;  5I1V A;  1JRO A;  3DQ0 A;  2PLI A;  2W54 A;  5I1W A;  1QLT A;  1W1K A;  1F0X A;  1N5W C;  5L6F A;  2Y3S A;  3POP A;  1AHV A;  3EUB 3;  5L6G A;  1DII A;  2E3T A;  5FXF A;  1AHZ A;  2BVF A;  1N63 C;  3D2D A;  1WVE A;  1V97 A;  3FW7 A;  2VFR A;  2VFU A;  4PWB A;  3LLB A;  1DZN A;  3HSU A;  1N60 C;  2Y08 A;  2W3R A;  2P13 A;  5AWV A;  2R8D A;  3S1F A;  2VFT A;  4EC3 A;  2OAI A;  2YVS A;  3C0P A;  1DIQ A;  1AHU A;  3NRZ B;  3D2J A;  2BVH A;  3ETR B;  3KJM A;  3TSJ A;  1I19 A;  1N61 C;  4PWC A;  3D2H A;  2VFS A;  1UXY A;  2UUV A;  5AE3 A;  4PVE A;  4JAY A;  4PVJ A;  2Q4W A; 
#chains in the Genus database with same CATH homology
 2GQU A;  1T3Q C;  3FW9 A;  3RJA A;  1W1R A;  3S1D A;  3NVZ B;  1MBT A;  3TSH A;  5HQX A;  3HRD C;  4PZF A;  1FFV C;  3JS8 A;  4BC7 A;  5ADZ A;  1VAO A;  1E8G A;  1FIQ B;  4PVH A;  5HHZ A;  3DED A;  4BC9 A;  2GQT A;  3AM9 A;  4PYT A;  2VAO A;  5HMR A;  3W8X A;  1WVF A;  2PLS A;  1MBB A;  3NVY B;  3NVV B;  1W1J A;  2WDW A;  2AXR A;  2Y4G A;  1FO4 A;  1ZR6 A;  1W1L A;  2UUU A;  2MBR A;  1FFU C;  5FXP A;  2BVG A;  4OAL A;  2W3S A;  2RK5 A;  4HG0 A;  3NVW B;  2W55 A;  1E8F A;  1W1Q A;  1SB3 B;  4BBY A;  2O3G A;  5D79 A;  4DNS A;  5FXE A;  3B9J B;  3PM9 A;  5G5H B;  4O95 A;  1HSK A;  4UD8 A;  2Y3R A;  5K8E A;  1VDV A;  2IPI A;  3SR6 B;  4XLO A;  2I0K A;  4ZOH B;  2VFV A;  5AE1 A;  2P3H A;  1RM6 B;  4ML8 A;  2NQW A;  1W1M A;  3RJ8 A;  4JB1 A;  2Q85 A;  2R2Z A;  1QLU A;  3FW8 A;  3AN1 A;  5FXD A;  3I99 A;  4BCA A;  2QKN A;  2QPM A;  3TX1 A;  3NS1 B;  1W1S A;  1WYG A;  4MLA A;  4PVK A;  1JRP A;  3W8Z A;  1ZXI C;  3PQB A;  3LAE A;  1E8H A;  1N62 C;  1E0Y A;  2P4P A;  1W1O A;  3S1E A;  3W8W A;  3BW7 A;  3FWA A;  5G5G B;  2EXR A;  3S1C A;  3AMZ A;  5AE2 A;  1N5X A;  3GSY A;  3VTE A;  5I1V A;  1JRO A;  3DQ0 A;  2PLI A;  2W54 A;  5I1W A;  1QLT A;  1W1K A;  1F0X A;  1N5W C;  5L6F A;  2Y3S A;  3POP A;  1AHV A;  3EUB 3;  5L6G A;  1DII A;  2E3T A;  5FXF A;  1AHZ A;  2BVF A;  1N63 C;  3D2D A;  1WVE A;  1V97 A;  3FW7 A;  2VFR A;  2VFU A;  4PWB A;  3LLB A;  1DZN A;  3HSU A;  1N60 C;  2Y08 A;  2W3R A;  2P13 A;  5AWV A;  2R8D A;  3S1F A;  2VFT A;  4EC3 A;  2OAI A;  2YVS A;  3C0P A;  1DIQ A;  1AHU A;  3NRZ B;  3D2J A;  2BVH A;  3ETR B;  3KJM A;  3TSJ A;  1I19 A;  1N61 C;  4PWC A;  3D2H A;  2VFS A;  1UXY A;  2UUV A;  5AE3 A;  4PVE A;  4JAY A;  4PVJ A;  2Q4W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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