1W1KA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: ile238thr mutant
Total Genus 182
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
182
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKTAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
total genus 182
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1kA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1kA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1kA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1kA03
2VFTA 5AE3A 3FW9A 2O3GA 3D2JA 3NS1B 4BBYA 1VDVA 1F0XA 2MBRA 3S1FA 3FW8A 1QLTA 1FFVC 2BVGA 2W54A 1AHUA 3VTEA 1RM6B 2AXRA 4ML8A 1N5WC 4PWBA 2P3HA 2PLIA 1JROA 1MBTA 1N63C 3KJMA 1W1JA 5G5GB 1FO4A 1N5XA 3W8ZA 4PVHA 1AHVA 1SB3B 2VFSA 2GQUA 3NVYB 2NQWA 2Q85A 1WVEA 3EUB3 1I19A 2E3TA 1WYGA 3NVZB 5ADZA 3W8WA 1V97A 3C0PA 3TSJA 1FFUC 2QKNA 4PYTA 3LLBA 5AE1A 4JAYA 1W1KA 2GQTA 1DIIA 1ZR6A 3DEDA 2VFVA 1W1QA 2VFRA 1HSKA 3JS8A 4BC9A 2R8DA 4PVKA 5D79A 4ZOHB 3TSHA 1N61C 5AE2A 4HG0A 1E8GA 1N60C 1W1SA 1W1LA 1DIQA 1DZNA 2W3SA 3I99A 4DNSA 4BC7A 5FXPA 1VAOA 2VFUA 3SR6B 1T3QC 4JB1A 3FW7A 3GSYA 4BCAA 3DQ0A 3TX1A 4O95A 2QPMA 5HMRA 1W1RA 3D2HA 3D2DA 2EXRA 2W55A 5HQXA 2BVFA 2Q4WA 3S1CA 5FXFA 5FXDA 1W1OA 2OAIA 2YVSA 1E8FA 3AN1A 3FWAA 3NRZB 3S1DA 2W3RA 5FXEA 2RK5A 5G5HB 3ETRB 4PVJA 4OALA 1FIQB 1E0YA 3NVWB 1JRPA 3W8XA 4PWCA 1E8HA 3B9JB 2P4PA 2I0KA 1N62C 4MLAA 1MBBA 3PM9A 3AM9A 2P13A 4EC3A 1UXYA 2VAOA 2BVHA 3LAEA 1WVFA 4PVEA 3HRDC 5HHZA 1ZXIC 3AMZA 2R2ZA 3NVVB 4UD8A 4PZFA 3BW7A 4XLOA 1QLUA 3S1EA 1W1MA 2PLSA 1AHZA
chains in the Genus database with same CATH superfamily
2VFTA 3RJ8A 5AE3A 3FW9A 2O3GA 3D2JA 3NS1B 4BBYA 1VDVA 2Y3SA 3HSUA 1F0XA 2MBRA 2Y08A 3S1FA 3FW8A 1QLTA 1FFVC 2BVGA 2W54A 1AHUA 3VTEA 1RM6B 2AXRA 4ML8A 1N5WC 4PWBA 2P3HA 2PLIA 1JROA 1MBTA 1N63C 3KJMA 1W1JA 5G5GB 1FO4A 1N5XA 3EJBB 4PVHA 1AHVA 3W8ZA 1SB3B 2VFSA 2GQUA 3NVYB 2NQWA 2Q85A 1WVEA 3EUB3 1I19A 2E3TA 1WYGA 3NVZB 5ADZA 3W8WA 5L6GA 1V97A 3C0PA 3TSJA 1FFUC 2QKNA 4PYTA 3EJEB 3LLBA 3EJDB 5AE1A 4JAYA 5K8EA 5AWVA 1W1KA 2GQTA 1DIIA 1ZR6A 3DEDA 2VFVA 1W1QA 2VFRA 1HSKA 3JS8A 4BC9A 2R8DA 2IPIA 4PVKA 5D79A 3PQBA 4ZOHB 3TSHA 5I1WA 1N61C 5AE2A 4HG0A 1E8GA 1N60C 1W1SA 1W1LA 1DIQA 1DZNA 2W3SA 3I99A 2Y4GA 4DNSA 4BC7A 3POPA 5FXPA 1VAOA 2VFUA 3SR6B 1T3QC 4JB1A 3FW7A 3GSYA 4BCAA 3DQ0A 2WDWA 5L6FA 3TX1A 4O95A 2QPMA 5HMRA 1W1RA 3D2HA 3D2DA 2EXRA 2W55A 5HQXA 2BVFA 2Q4WA 2UUVA 3S1CA 5FXFA 5FXDA 1W1OA 2OAIA 2YVSA 1E8FA 3AN1A 3FWAA 3NRZB 3S1DA 2W3RA 5FXEA 2RK5A 5G5HB 3ETRB 4PVJA 4OALA 1FIQB 5I1VA 1E0YA 3NVWB 1JRPA 3W8XA 4PWCA 1E8HA 3B9JB 2P4PA 2I0KA 1N62C 2UUUA 4MLAA 1MBBA 3PM9A 3AM9A 2P13A 4EC3A 1UXYA 2VAOA 2BVHA 3LAEA 3RJAA 1WVFA 4PVEA 3HRDC 5HHZA 1ZXIC 3AMZA 3NVVB 2R2ZA 4UD8A 4PZFA 3BW7A 4XLOA 1QLUA 3S1EA 1W1MA 2Y3RA 2PLSA 1AHZA
chains in the Genus database with same CATH topology
2VFTA 3RJ8A 5AE3A 3FW9A 2O3GA 3D2JA 3NS1B 4BBYA 1VDVA 2Y3SA 3HSUA 1F0XA 2MBRA 2Y08A 3S1FA 3FW8A 1QLTA 1FFVC 2BVGA 2W54A 1AHUA 3VTEA 1RM6B 2AXRA 4ML8A 1N5WC 4PWBA 2P3HA 2PLIA 1JROA 1MBTA 1N63C 3KJMA 1W1JA 5G5GB 1FO4A 1N5XA 3W8ZA 4PVHA 1AHVA 1SB3B 2VFSA 2GQUA 3NVYB 2NQWA 2Q85A 1WVEA 3EUB3 1I19A 2E3TA 1WYGA 3NVZB 5ADZA 3W8WA 5L6GA 1V97A 3C0PA 3TSJA 1FFUC 2QKNA 4PYTA 3LLBA 5AE1A 4JAYA 5K8EA 5AWVA 1W1KA 2GQTA 1DIIA 1ZR6A 3DEDA 2VFVA 1W1QA 2VFRA 1HSKA 3JS8A 4BC9A 2R8DA 2IPIA 4PVKA 5D79A 3PQBA 4ZOHB 3TSHA 5I1WA 1N61C 5AE2A 4HG0A 1E8GA 1N60C 1W1SA 1W1LA 1DIQA 1DZNA 2W3SA 3I99A 2Y4GA 4DNSA 4BC7A 3POPA 5FXPA 1VAOA 2VFUA 3SR6B 1T3QC 4JB1A 3FW7A 3GSYA 4BCAA 3DQ0A 2WDWA 5L6FA 3TX1A 4O95A 2QPMA 5HMRA 1W1RA 3D2HA 3D2DA 2EXRA 2W55A 5HQXA 2BVFA 2Q4WA 2UUVA 3S1CA 5FXFA 5FXDA 1W1OA 2OAIA 2YVSA 1E8FA 3AN1A 3FWAA 3NRZB 3S1DA 2W3RA 5FXEA 2RK5A 5G5HB 3ETRB 4PVJA 4OALA 1FIQB 5I1VA 1E0YA 3NVWB 1JRPA 3W8XA 4PWCA 1E8HA 3B9JB 2P4PA 2I0KA 1N62C 2UUUA 4MLAA 1MBBA 3PM9A 3AM9A 2P13A 4EC3A 1UXYA 2VAOA 2BVHA 3LAEA 3RJAA 1WVFA 4PVEA 3HRDC 5HHZA 1ZXIC 3AMZA 2R2ZA 3NVVB 4UD8A 4PZFA 3BW7A 4XLOA 1QLUA 3S1EA 1W1MA 2Y3RA 2PLSA 1AHZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VFT A;  5AE3 A;  3FW9 A;  2O3G A;  3D2J A;  3NS1 B;  4BBY A;  1VDV A;  1F0X A;  2MBR A;  3S1F A;  3FW8 A;  1QLT A;  1FFV C;  2BVG A;  2W54 A;  1AHU A;  3VTE A;  1RM6 B;  2AXR A;  4ML8 A;  1N5W C;  4PWB A;  2P3H A;  2PLI A;  1JRO A;  1MBT A;  1N63 C;  3KJM A;  1W1J A;  5G5G B;  1FO4 A;  1N5X A;  3W8Z A;  4PVH A;  1AHV A;  1SB3 B;  2VFS A;  2GQU A;  3NVY B;  2NQW A;  2Q85 A;  1WVE A;  3EUB 3;  1I19 A;  2E3T A;  1WYG A;  3NVZ B;  5ADZ A;  3W8W A;  1V97 A;  3C0P A;  3TSJ A;  1FFU C;  2QKN A;  4PYT A;  3LLB A;  5AE1 A;  4JAY A;  1W1K A;  2GQT A;  1DII A;  1ZR6 A;  3DED A;  2VFV A;  1W1Q A;  2VFR A;  1HSK A;  3JS8 A;  4BC9 A;  2R8D A;  4PVK A;  5D79 A;  4ZOH B;  3TSH A;  1N61 C;  5AE2 A;  4HG0 A;  1E8G A;  1N60 C;  1W1S A;  1W1L A;  1DIQ A;  1DZN A;  2W3S A;  3I99 A;  4DNS A;  4BC7 A;  5FXP A;  1VAO A;  2VFU A;  3SR6 B;  1T3Q C;  4JB1 A;  3FW7 A;  3GSY A;  4BCA A;  3DQ0 A;  3TX1 A;  4O95 A;  2QPM A;  5HMR A;  1W1R A;  3D2H A;  3D2D A;  2EXR A;  2W55 A;  5HQX A;  2BVF A;  2Q4W A;  3S1C A;  5FXF A;  5FXD A;  1W1O A;  2OAI A;  2YVS A;  1E8F A;  3AN1 A;  3FWA A;  3NRZ B;  3S1D A;  2W3R A;  5FXE A;  2RK5 A;  5G5H B;  3ETR B;  4PVJ A;  4OAL A;  1FIQ B;  1E0Y A;  3NVW B;  1JRP A;  3W8X A;  4PWC A;  1E8H A;  3B9J B;  2P4P A;  2I0K A;  1N62 C;  4MLA A;  1MBB A;  3PM9 A;  3AM9 A;  2P13 A;  4EC3 A;  1UXY A;  2VAO A;  2BVH A;  3LAE A;  1WVF A;  4PVE A;  3HRD C;  5HHZ A;  1ZXI C;  3AMZ A;  2R2Z A;  3NVV B;  4UD8 A;  4PZF A;  3BW7 A;  4XLO A;  1QLU A;  3S1E A;  1W1M A;  2PLS A;  1AHZ A; 
#chains in the Genus database with same CATH topology
 2VFT A;  3RJ8 A;  5AE3 A;  3FW9 A;  2O3G A;  3D2J A;  3NS1 B;  4BBY A;  1VDV A;  2Y3S A;  3HSU A;  1F0X A;  2MBR A;  2Y08 A;  3S1F A;  3FW8 A;  1QLT A;  1FFV C;  2BVG A;  2W54 A;  1AHU A;  3VTE A;  1RM6 B;  2AXR A;  4ML8 A;  1N5W C;  4PWB A;  2P3H A;  2PLI A;  1JRO A;  1MBT A;  1N63 C;  3KJM A;  1W1J A;  5G5G B;  1FO4 A;  1N5X A;  3EJB B;  4PVH A;  1AHV A;  3W8Z A;  1SB3 B;  2VFS A;  2GQU A;  3NVY B;  2NQW A;  2Q85 A;  1WVE A;  3EUB 3;  1I19 A;  2E3T A;  1WYG A;  3NVZ B;  5ADZ A;  3W8W A;  5L6G A;  1V97 A;  3C0P A;  3TSJ A;  1FFU C;  2QKN A;  4PYT A;  3EJE B;  3LLB A;  3EJD B;  5AE1 A;  4JAY A;  5K8E A;  5AWV A;  1W1K A;  2GQT A;  1DII A;  1ZR6 A;  3DED A;  2VFV A;  1W1Q A;  2VFR A;  1HSK A;  3JS8 A;  4BC9 A;  2R8D A;  2IPI A;  4PVK A;  5D79 A;  3PQB A;  4ZOH B;  3TSH A;  5I1W A;  1N61 C;  5AE2 A;  4HG0 A;  1E8G A;  1N60 C;  1W1S A;  1W1L A;  1DIQ A;  1DZN A;  2W3S A;  3I99 A;  2Y4G A;  4DNS A;  4BC7 A;  3POP A;  5FXP A;  1VAO A;  2VFU A;  3SR6 B;  1T3Q C;  4JB1 A;  3FW7 A;  3GSY A;  4BCA A;  3DQ0 A;  2WDW A;  5L6F A;  3TX1 A;  4O95 A;  2QPM A;  5HMR A;  1W1R A;  3D2H A;  3D2D A;  2EXR A;  2W55 A;  5HQX A;  2BVF A;  2Q4W A;  2UUV A;  3S1C A;  5FXF A;  5FXD A;  1W1O A;  2OAI A;  2YVS A;  1E8F A;  3AN1 A;  3FWA A;  3NRZ B;  3S1D A;  2W3R A;  5FXE A;  2RK5 A;  5G5H B;  3ETR B;  4PVJ A;  4OAL A;  1FIQ B;  5I1V A;  1E0Y A;  3NVW B;  1JRP A;  3W8X A;  4PWC A;  1E8H A;  3B9J B;  2P4P A;  2I0K A;  1N62 C;  2UUU A;  4MLA A;  1MBB A;  3PM9 A;  3AM9 A;  2P13 A;  4EC3 A;  1UXY A;  2VAO A;  2BVH A;  3LAE A;  3RJA A;  1WVF A;  4PVE A;  3HRD C;  5HHZ A;  1ZXI C;  3AMZ A;  3NVV B;  2R2Z A;  4UD8 A;  4PZF A;  3BW7 A;  4XLO A;  1QLU A;  3S1E A;  1W1M A;  2Y3R A;  2PLS A;  1AHZ A; 
#chains in the Genus database with same CATH homology
 2VFT A;  3RJ8 A;  5AE3 A;  3FW9 A;  2O3G A;  3D2J A;  3NS1 B;  4BBY A;  1VDV A;  2Y3S A;  3HSU A;  1F0X A;  2MBR A;  2Y08 A;  3S1F A;  3FW8 A;  1QLT A;  1FFV C;  2BVG A;  2W54 A;  1AHU A;  3VTE A;  1RM6 B;  2AXR A;  4ML8 A;  1N5W C;  4PWB A;  2P3H A;  2PLI A;  1JRO A;  1MBT A;  1N63 C;  3KJM A;  1W1J A;  5G5G B;  1FO4 A;  1N5X A;  3W8Z A;  4PVH A;  1AHV A;  1SB3 B;  2VFS A;  2GQU A;  3NVY B;  2NQW A;  2Q85 A;  1WVE A;  3EUB 3;  1I19 A;  2E3T A;  1WYG A;  3NVZ B;  5ADZ A;  3W8W A;  5L6G A;  1V97 A;  3C0P A;  3TSJ A;  1FFU C;  2QKN A;  4PYT A;  3LLB A;  5AE1 A;  4JAY A;  5K8E A;  5AWV A;  1W1K A;  2GQT A;  1DII A;  1ZR6 A;  3DED A;  2VFV A;  1W1Q A;  2VFR A;  1HSK A;  3JS8 A;  4BC9 A;  2R8D A;  2IPI A;  4PVK A;  5D79 A;  3PQB A;  4ZOH B;  3TSH A;  5I1W A;  1N61 C;  5AE2 A;  4HG0 A;  1E8G A;  1N60 C;  1W1S A;  1W1L A;  1DIQ A;  1DZN A;  2W3S A;  3I99 A;  2Y4G A;  4DNS A;  4BC7 A;  3POP A;  5FXP A;  1VAO A;  2VFU A;  3SR6 B;  1T3Q C;  4JB1 A;  3FW7 A;  3GSY A;  4BCA A;  3DQ0 A;  2WDW A;  5L6F A;  3TX1 A;  4O95 A;  2QPM A;  5HMR A;  1W1R A;  3D2H A;  3D2D A;  2EXR A;  2W55 A;  5HQX A;  2BVF A;  2Q4W A;  2UUV A;  3S1C A;  5FXF A;  5FXD A;  1W1O A;  2OAI A;  2YVS A;  1E8F A;  3AN1 A;  3FWA A;  3NRZ B;  3S1D A;  2W3R A;  5FXE A;  2RK5 A;  5G5H B;  3ETR B;  4PVJ A;  4OAL A;  1FIQ B;  5I1V A;  1E0Y A;  3NVW B;  1JRP A;  3W8X A;  4PWC A;  1E8H A;  3B9J B;  2P4P A;  2I0K A;  1N62 C;  2UUU A;  4MLA A;  1MBB A;  3PM9 A;  3AM9 A;  2P13 A;  4EC3 A;  1UXY A;  2VAO A;  2BVH A;  3LAE A;  3RJA A;  1WVF A;  4PVE A;  3HRD C;  5HHZ A;  1ZXI C;  3AMZ A;  2R2Z A;  3NVV B;  4UD8 A;  4PZF A;  3BW7 A;  4XLO A;  1QLU A;  3S1E A;  1W1M A;  2Y3R A;  2PLS A;  1AHZ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...