1W1KA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: ile238thr mutant
Total Genus 182
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
182
sequence length
555
structure length
550
Chain Sequence
b'EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKTAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
total genus 182
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1kA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1kA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1kA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1kA03
3I99A 1SB3B 1FIQB 2BVGA 4BCAA 2W3RA 5HMRA 3GSYA 5HHZA 4PWBA 1W1KA 2VFSA 3B9JB 3FWAA 3TSJA 1V97A 4UD8A 2BVFA 4OALA 3HRDC 1W1MA 4JAYA 3W8XA 3NVYB 2EXRA 1E8HA 2Q4WA 3D2JA 3FW9A 2VFTA 1E8GA 5AE3A 2W3SA 3NS1B 5FXPA 3TSHA 1W1QA 1W1LA 1MBTA 2NQWA 2YVSA 2QPMA 3LAEA 2W55A 3SR6B 1W1SA 3BW7A 5FXDA 1W1OA 2PLIA 1N61C 1WVFA 1MBBA 1ZR6A 2P3HA 1FO4A 5AE1A 2P13A 2R8DA 4PWCA 4O95A 5FXEA 1WYGA 3DQ0A 1W1RA 5AE2A 2P4PA 1N5XA 2Q85A 2R2ZA 3KJMA 2VFUA 3AMZA 4DNSA 2BVHA 1E8FA 3S1CA 3NVVB 4HG0A 3NRZB 1HSKA 5G5GB 4MLAA 2AXRA 4JB1A 3S1FA 4ZOHB 4PVHA 1N5WC 1AHUA 1E0YA 1AHZA 3W8WA 1FFVC 3AN1A 5FXFA 2E3TA 2RK5A 2VFRA 4BC9A 1WVEA 2W54A 3S1EA 1AHVA 1W1JA 1T3QC 4BBYA 4PVEA 4PZFA 3D2DA 2PLSA 4PVKA 1N60C 3TX1A 1VAOA 4ML8A 4XLOA 2GQTA 3NVWB 3LLBA 2GQUA 3FW8A 2O3GA 3W8ZA 2VAOA 1FFUC 1DIQA 4PVJA 1QLTA 3NVZB 4PYTA 3C0PA 5D79A 3S1DA 1UXYA 1N62C 1RM6B 1N63C 4EC3A 3DEDA 2MBRA 1JROA 1VDVA 3VTEA 1ZXIC 2QKNA 1QLUA 1JRPA 2VFVA 1I19A 3AM9A 1DIIA 3JS8A 5G5HB 3EUB3 2OAIA 3PM9A 4BC7A 1DZNA 2I0KA 5ADZA 1F0XA 5HQXA 3D2HA 3ETRB 3FW7A
chains in the Genus database with same CATH superfamily
3I99A 1SB3B 1FIQB 2BVGA 4BCAA 2W3RA 5HMRA 3GSYA 5HHZA 3PQBA 4PWBA 1W1KA 2VFSA 3B9JB 3EJDB 3FWAA 3TSJA 1V97A 4UD8A 2BVFA 4OALA 3HRDC 1W1MA 4JAYA 3W8XA 2IPIA 3RJAA 5K8EA 3NVYB 2EXRA 1E8HA 2Q4WA 3D2JA 3FW9A 2VFTA 1E8GA 5AE3A 2W3SA 3NS1B 2Y08A 5FXPA 3TSHA 1W1QA 1W1LA 1MBTA 2NQWA 2YVSA 2QPMA 3LAEA 2W55A 3SR6B 1W1SA 3BW7A 5FXDA 1W1OA 2Y3RA 2PLIA 1N61C 1WVFA 1MBBA 1ZR6A 2P3HA 1FO4A 5AE1A 2P13A 2R8DA 4PWCA 4O95A 5FXEA 1WYGA 3DQ0A 1W1RA 5AE2A 2P4PA 1N5XA 2Q85A 2R2ZA 5I1WA 3KJMA 2VFUA 3AMZA 4DNSA 2BVHA 1E8FA 3NVVB 3S1CA 4HG0A 3NRZB 1HSKA 5G5GB 4MLAA 2AXRA 4JB1A 3S1FA 4ZOHB 2Y4GA 4PVHA 1N5WC 1AHUA 1E0YA 1AHZA 3W8WA 1FFVC 3AN1A 5FXFA 2E3TA 2RK5A 2VFRA 5L6GA 4BC9A 1WVEA 2W54A 3S1EA 1AHVA 1W1JA 1T3QC 4BBYA 4PVEA 4PZFA 3D2DA 2PLSA 3EJBB 2UUUA 4PVKA 1N60C 3TX1A 1VAOA 4ML8A 2Y3SA 4XLOA 5L6FA 2GQTA 3EJEB 3NVWB 3LLBA 2GQUA 3FW8A 2O3GA 5I1VA 3W8ZA 2VAOA 1FFUC 1DIQA 4PVJA 1QLTA 3NVZB 4PYTA 3C0PA 5D79A 3S1DA 1UXYA 1N62C 1RM6B 2WDWA 1N63C 4EC3A 3POPA 3DEDA 2MBRA 1JROA 1VDVA 3RJ8A 3VTEA 1ZXIC 2QKNA 1QLUA 1JRPA 2VFVA 1I19A 3AM9A 1DIIA 3HSUA 3JS8A 5G5HB 3EUB3 2OAIA 2UUVA 5AWVA 3PM9A 4BC7A 1DZNA 2I0KA 5ADZA 1F0XA 5HQXA 3D2HA 3ETRB 3FW7A
chains in the Genus database with same CATH topology
3I99A 1SB3B 1FIQB 2BVGA 4BCAA 2W3RA 5HMRA 3GSYA 5HHZA 3PQBA 4PWBA 1W1KA 2VFSA 3B9JB 3FWAA 3TSJA 1V97A 4UD8A 2BVFA 4OALA 3HRDC 1W1MA 4JAYA 3W8XA 2IPIA 3RJAA 5K8EA 3NVYB 2EXRA 1E8HA 2Q4WA 3D2JA 3FW9A 2VFTA 1E8GA 5AE3A 2W3SA 3NS1B 2Y08A 5FXPA 3TSHA 1W1QA 1W1LA 1MBTA 2NQWA 2YVSA 2QPMA 3LAEA 2W55A 3SR6B 1W1SA 3BW7A 5FXDA 1W1OA 2Y3RA 2PLIA 1N61C 1WVFA 1MBBA 1ZR6A 2P3HA 1FO4A 5AE1A 2P13A 2R8DA 4PWCA 4O95A 5FXEA 1WYGA 3DQ0A 1W1RA 5AE2A 2P4PA 1N5XA 2Q85A 2R2ZA 5I1WA 3KJMA 2VFUA 3AMZA 4DNSA 2BVHA 1E8FA 3S1CA 3NVVB 4HG0A 3NRZB 1HSKA 5G5GB 4MLAA 2AXRA 4JB1A 3S1FA 4ZOHB 2Y4GA 4PVHA 1N5WC 1AHUA 1E0YA 1AHZA 3W8WA 1FFVC 3AN1A 5FXFA 2E3TA 2RK5A 2VFRA 5L6GA 4BC9A 1WVEA 2W54A 3S1EA 1AHVA 1W1JA 1T3QC 4BBYA 4PVEA 4PZFA 3D2DA 2PLSA 2UUUA 4PVKA 1N60C 3TX1A 1VAOA 4ML8A 2Y3SA 4XLOA 5L6FA 2GQTA 3NVWB 3LLBA 2GQUA 3FW8A 2O3GA 5I1VA 3W8ZA 2VAOA 1FFUC 1DIQA 4PVJA 1QLTA 3NVZB 4PYTA 3C0PA 5D79A 3S1DA 1UXYA 1N62C 1RM6B 2WDWA 1N63C 4EC3A 3POPA 3DEDA 2MBRA 1JROA 1VDVA 3RJ8A 3VTEA 1ZXIC 2QKNA 1QLUA 1JRPA 2VFVA 1I19A 3AM9A 1DIIA 3HSUA 3JS8A 5G5HB 3EUB3 2OAIA 2UUVA 5AWVA 3PM9A 4BC7A 1DZNA 2I0KA 5ADZA 1F0XA 5HQXA 3D2HA 3ETRB 3FW7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I99 A;  1SB3 B;  1FIQ B;  2BVG A;  4BCA A;  2W3R A;  5HMR A;  3GSY A;  5HHZ A;  4PWB A;  1W1K A;  2VFS A;  3B9J B;  3FWA A;  3TSJ A;  1V97 A;  4UD8 A;  2BVF A;  4OAL A;  3HRD C;  1W1M A;  4JAY A;  3W8X A;  3NVY B;  2EXR A;  1E8H A;  2Q4W A;  3D2J A;  3FW9 A;  2VFT A;  1E8G A;  5AE3 A;  2W3S A;  3NS1 B;  5FXP A;  3TSH A;  1W1Q A;  1W1L A;  1MBT A;  2NQW A;  2YVS A;  2QPM A;  3LAE A;  2W55 A;  3SR6 B;  1W1S A;  3BW7 A;  5FXD A;  1W1O A;  2PLI A;  1N61 C;  1WVF A;  1MBB A;  1ZR6 A;  2P3H A;  1FO4 A;  5AE1 A;  2P13 A;  2R8D A;  4PWC A;  4O95 A;  5FXE A;  1WYG A;  3DQ0 A;  1W1R A;  5AE2 A;  2P4P A;  1N5X A;  2Q85 A;  2R2Z A;  3KJM A;  2VFU A;  3AMZ A;  4DNS A;  2BVH A;  1E8F A;  3S1C A;  3NVV B;  4HG0 A;  3NRZ B;  1HSK A;  5G5G B;  4MLA A;  2AXR A;  4JB1 A;  3S1F A;  4ZOH B;  4PVH A;  1N5W C;  1AHU A;  1E0Y A;  1AHZ A;  3W8W A;  1FFV C;  3AN1 A;  5FXF A;  2E3T A;  2RK5 A;  2VFR A;  4BC9 A;  1WVE A;  2W54 A;  3S1E A;  1AHV A;  1W1J A;  1T3Q C;  4BBY A;  4PVE A;  4PZF A;  3D2D A;  2PLS A;  4PVK A;  1N60 C;  3TX1 A;  1VAO A;  4ML8 A;  4XLO A;  2GQT A;  3NVW B;  3LLB A;  2GQU A;  3FW8 A;  2O3G A;  3W8Z A;  2VAO A;  1FFU C;  1DIQ A;  4PVJ A;  1QLT A;  3NVZ B;  4PYT A;  3C0P A;  5D79 A;  3S1D A;  1UXY A;  1N62 C;  1RM6 B;  1N63 C;  4EC3 A;  3DED A;  2MBR A;  1JRO A;  1VDV A;  3VTE A;  1ZXI C;  2QKN A;  1QLU A;  1JRP A;  2VFV A;  1I19 A;  3AM9 A;  1DII A;  3JS8 A;  5G5H B;  3EUB 3;  2OAI A;  3PM9 A;  4BC7 A;  1DZN A;  2I0K A;  5ADZ A;  1F0X A;  5HQX A;  3D2H A;  3ETR B;  3FW7 A; 
#chains in the Genus database with same CATH topology
 3I99 A;  1SB3 B;  1FIQ B;  2BVG A;  4BCA A;  2W3R A;  5HMR A;  3GSY A;  5HHZ A;  3PQB A;  4PWB A;  1W1K A;  2VFS A;  3B9J B;  3EJD B;  3FWA A;  3TSJ A;  1V97 A;  4UD8 A;  2BVF A;  4OAL A;  3HRD C;  1W1M A;  4JAY A;  3W8X A;  2IPI A;  3RJA A;  5K8E A;  3NVY B;  2EXR A;  1E8H A;  2Q4W A;  3D2J A;  3FW9 A;  2VFT A;  1E8G A;  5AE3 A;  2W3S A;  3NS1 B;  2Y08 A;  5FXP A;  3TSH A;  1W1Q A;  1W1L A;  1MBT A;  2NQW A;  2YVS A;  2QPM A;  3LAE A;  2W55 A;  3SR6 B;  1W1S A;  3BW7 A;  5FXD A;  1W1O A;  2Y3R A;  2PLI A;  1N61 C;  1WVF A;  1MBB A;  1ZR6 A;  2P3H A;  1FO4 A;  5AE1 A;  2P13 A;  2R8D A;  4PWC A;  4O95 A;  5FXE A;  1WYG A;  3DQ0 A;  1W1R A;  5AE2 A;  2P4P A;  1N5X A;  2Q85 A;  2R2Z A;  5I1W A;  3KJM A;  2VFU A;  3AMZ A;  4DNS A;  2BVH A;  1E8F A;  3NVV B;  3S1C A;  4HG0 A;  3NRZ B;  1HSK A;  5G5G B;  4MLA A;  2AXR A;  4JB1 A;  3S1F A;  4ZOH B;  2Y4G A;  4PVH A;  1N5W C;  1AHU A;  1E0Y A;  1AHZ A;  3W8W A;  1FFV C;  3AN1 A;  5FXF A;  2E3T A;  2RK5 A;  2VFR A;  5L6G A;  4BC9 A;  1WVE A;  2W54 A;  3S1E A;  1AHV A;  1W1J A;  1T3Q C;  4BBY A;  4PVE A;  4PZF A;  3D2D A;  2PLS A;  3EJB B;  2UUU A;  4PVK A;  1N60 C;  3TX1 A;  1VAO A;  4ML8 A;  2Y3S A;  4XLO A;  5L6F A;  2GQT A;  3EJE B;  3NVW B;  3LLB A;  2GQU A;  3FW8 A;  2O3G A;  5I1V A;  3W8Z A;  2VAO A;  1FFU C;  1DIQ A;  4PVJ A;  1QLT A;  3NVZ B;  4PYT A;  3C0P A;  5D79 A;  3S1D A;  1UXY A;  1N62 C;  1RM6 B;  2WDW A;  1N63 C;  4EC3 A;  3POP A;  3DED A;  2MBR A;  1JRO A;  1VDV A;  3RJ8 A;  3VTE A;  1ZXI C;  2QKN A;  1QLU A;  1JRP A;  2VFV A;  1I19 A;  3AM9 A;  1DII A;  3HSU A;  3JS8 A;  5G5H B;  3EUB 3;  2OAI A;  2UUV A;  5AWV A;  3PM9 A;  4BC7 A;  1DZN A;  2I0K A;  5ADZ A;  1F0X A;  5HQX A;  3D2H A;  3ETR B;  3FW7 A; 
#chains in the Genus database with same CATH homology
 3I99 A;  1SB3 B;  1FIQ B;  2BVG A;  4BCA A;  2W3R A;  5HMR A;  3GSY A;  5HHZ A;  3PQB A;  4PWB A;  1W1K A;  2VFS A;  3B9J B;  3FWA A;  3TSJ A;  1V97 A;  4UD8 A;  2BVF A;  4OAL A;  3HRD C;  1W1M A;  4JAY A;  3W8X A;  2IPI A;  3RJA A;  5K8E A;  3NVY B;  2EXR A;  1E8H A;  2Q4W A;  3D2J A;  3FW9 A;  2VFT A;  1E8G A;  5AE3 A;  2W3S A;  3NS1 B;  2Y08 A;  5FXP A;  3TSH A;  1W1Q A;  1W1L A;  1MBT A;  2NQW A;  2YVS A;  2QPM A;  3LAE A;  2W55 A;  3SR6 B;  1W1S A;  3BW7 A;  5FXD A;  1W1O A;  2Y3R A;  2PLI A;  1N61 C;  1WVF A;  1MBB A;  1ZR6 A;  2P3H A;  1FO4 A;  5AE1 A;  2P13 A;  2R8D A;  4PWC A;  4O95 A;  5FXE A;  1WYG A;  3DQ0 A;  1W1R A;  5AE2 A;  2P4P A;  1N5X A;  2Q85 A;  2R2Z A;  5I1W A;  3KJM A;  2VFU A;  3AMZ A;  4DNS A;  2BVH A;  1E8F A;  3S1C A;  3NVV B;  4HG0 A;  3NRZ B;  1HSK A;  5G5G B;  4MLA A;  2AXR A;  4JB1 A;  3S1F A;  4ZOH B;  2Y4G A;  4PVH A;  1N5W C;  1AHU A;  1E0Y A;  1AHZ A;  3W8W A;  1FFV C;  3AN1 A;  5FXF A;  2E3T A;  2RK5 A;  2VFR A;  5L6G A;  4BC9 A;  1WVE A;  2W54 A;  3S1E A;  1AHV A;  1W1J A;  1T3Q C;  4BBY A;  4PVE A;  4PZF A;  3D2D A;  2PLS A;  2UUU A;  4PVK A;  1N60 C;  3TX1 A;  1VAO A;  4ML8 A;  2Y3S A;  4XLO A;  5L6F A;  2GQT A;  3NVW B;  3LLB A;  2GQU A;  3FW8 A;  2O3G A;  5I1V A;  3W8Z A;  2VAO A;  1FFU C;  1DIQ A;  4PVJ A;  1QLT A;  3NVZ B;  4PYT A;  3C0P A;  5D79 A;  3S1D A;  1UXY A;  1N62 C;  1RM6 B;  2WDW A;  1N63 C;  4EC3 A;  3POP A;  3DED A;  2MBR A;  1JRO A;  1VDV A;  3RJ8 A;  3VTE A;  1ZXI C;  2QKN A;  1QLU A;  1JRP A;  2VFV A;  1I19 A;  3AM9 A;  1DII A;  3HSU A;  3JS8 A;  5G5H B;  3EUB 3;  2OAI A;  2UUV A;  5AWV A;  3PM9 A;  4BC7 A;  1DZN A;  2I0K A;  5ADZ A;  1F0X A;  5HQX A;  3D2H A;  3ETR B;  3FW7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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