The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
115
|
sequence length |
324
|
structure length |
324
|
Chain Sequence |
AQMTMVQAITDALRIELKNDPNVLIFGEDVGVNGGVFRATEGLQAEFGEDRVFDTPLAESGIGGLAIGLALQGFRPVPEIQFFGFVYEVMDSICGQMARIRYRTGGRYHMPITIRSPFGGGVHTPELHSDSLEGLVAQQPGLKVVIPSTPYDAKGLLISAIRDNDPVIFLEHLKLYRSFRQEVPEGEYTIPIGKADIKREGKDITIIAYGAMVHESLKAAAELEKEGISAEVVDLRTVQPLDIETIIGSVEKTGRAIVVQEAQRQAGIAANVVAEINERAILSLEAPVLRVAAPDTVYPFAQAESVWLPNFKDVIETAKKVMNF
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
A molecular switch and proton wire synchronize the active sites in thiamine enzymes.
pubmed doi rcsb |
| source organism |
Geobacillus stearothermophilus
|
| molecule tags |
Oxidoreductase
|
| molecule keywords |
PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT
|
| total genus |
115
|
| structure length |
324
|
| sequence length |
324
|
| chains with identical sequence |
D, F, H
|
| ec nomenclature |
ec
1.2.4.1: Pyruvate dehydrogenase (acetyl-transferring). |
| pdb deposition date | 2004-09-16 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| B | PF02779 | Transket_pyr | Transketolase, pyrimidine binding domain |
| B | PF02780 | Transketolase_C | Transketolase, C-terminal domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Rossmann fold | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Rossmann fold |
