1WCHA

Crystal structure of ptpl1 human tyrosine phosphatase mutated in colorectal cancer - evidence for a second phosphotyrosine substrate recognition pocket
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
308
structure length
308
Chain Sequence
HSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structure of Ptpl1/Fap-1 Human Tyrosine Phosphatase Mutated in Colorectal Cancer: Eveidence for a Second Phosphotyrosine Substrate Recognition Pocket
pubmed doi rcsb
molecule keywords PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 13
molecule tags Hydrolase
source organism Homo sapiens
total genus 102
structure length 308
sequence length 308
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1wchA00
2BGEA 3SMEA 2NTAA 4OHIA 4GRYA 2VEWA 1T48A 5K9VA 1OHDA 4KYRA 4HJPA 5KAAA 2H03A 1X24A 4YAAA 2A8BA 2QDCA 2VEUA 1Q1MA 5KA7A 3EMUA 2QDPA 2H4VA 2CM2A 5EHRA 2CM3A 1MKPA 2F71A 2CM7A 3O4UA 2I6MA 4HRFA 1PYNA 2I1YA 3S3HA 5KA0A 3S4EA 1FPZA 2OC3A 2GJTA 2FJNA 2JJDA 2R0BA 2Y96A 1G7GA 2HC2A 1KAVA 5AWXA 1ZCLA 3QCNA 5GTJA 2B4PA 4Z6BA 3GXGA 1C86A 2BGDA 4GWFA 2WGPA 1EEOA 1BZHA 5I6VA 2F6YA 3F9AA 2VEYA 3QCLA 2CNFA 2FH7A 4PVGA 2H4GA 4GE6A 1JF7A 2CNEA 3NMEA 4RKKA 1WRMA 4JMKA 2CJZA 2MBCA 3V0JA 5KA4A 3QCHA 1XM2A 4I8NA 1G1GA 3BLTA 3ZM3A 4H1OA 3QCIA 1C87A 2IMGA 1XBOA 2F70A 2B4UA 1L8GA 2ESBA 4ZRTA 3I7ZA 4PYHA 1ECVA 3I80A 5KA3A 3QCGA 2B3OA 1G1HA 4QUNA 5KA9A 4GE5A 2I6JA 2AZRA 4DGXA 2F6ZA 2I75A 3OMHA 3B7OA 1NWEA 2BV5A 2PA5A 1GWZA 1ONZA 2PBNA 3V0DA 2F6TA 2CNGA 1YN9A 3QCKA 1YPTA 2I4HA 2C7SA 4Y14A 5KA1A 3BM8A 1G7FA 2HCMA 4JMJA 2B07A 2BZLA 2Q05A 4ERCA 4QBEA 2J17A 3N0AA 2I6PA 1U24A 1LYVA 1ZCKA 3S4OA 4D3RA 3BRHA 2OUDA 4RI4A 4NYHA 5M43A 3ZM1A 1KAKA 1YGRA 5BX1A 4JBCA 2NT7A 3EAXA 1ZC0A 2FJMA 1OEVA 1YGUA 4Y2EA 2RF6A 3O5XA 2YDUA 2CMAA 2J16A 1XXVA 4J51A 1T49A 1BZJA 3U96A 3RZ2A 2NLKA 1LQFA 3CM3A 3QCEA 4KYQA 1YWFA 4DGPA 1LARA 3RO1A 5IBMA 4TVVA 2M3VA 1I57A 1I9SA 2I4EA 3QCJA 3V0IA 1WAXA 2ZN7A 3RGQA 2NZ6A 3SR9A 2G59A 3QCCA 2E0TA 2NT2A 5K23A 2HVLA 1PTYA 2HXPA 3MOWA 2PT0A 5K24A 2P4DA 1AAXA 4MBBA 3EU0A 1U25A 2VEVA 4NNDA 1PA1A 5K22A 1M3GA 3PS5A 2HNQA 2I42A 5BZZA 1NO6A 4WU2A 3D1OA 3O4TA 3LJ8A 4QAHA 4AZ1A 1C85A 1G4WR 3AWEA 1QZ0A 2GP0A 2Y2FA 1Q6TA 2NV5A 2B4OA 5MMZB 2I3RA 4R30A 5BUGA 1ONYA 2F6WA 3D1HA 2PI7A 4RHGA 3OLRA 1OEMX 1YTWA 1U26A 2H4KA 2DXPA 2P6XA 5K9WA 1GFYA 1PTVA 3QCFA 1R6HA 5KACA 5KABA 2CNHA 3S3EA 1G1FA 3ZV2A 2I6OA 2CNIA 1FQ1A 2HNPA 3S3KA 1C83A 2SHPA 2CMCA 1Q6MA 2QBRA 3QCBA 1SUGA 1Q6SA 1EENA 2CFVA 3A5JA 3V0FA 5HDEA 1YTSA 4NWFA 4RDDA 3QCMA 2QBPA 2C46A 3F41A 4QBWA 1T4JA 1YZ4A 2CM8A 2GWOA 1L8KA 5KA8A 5J8RA 3F81A 1C84A 2I4GA 3ZM0A 1RXDA 3F9BA 2OZ5A 4NWGA 2QDMA 3I36A 4R0TA 5KA2A 1C88A 5KADA 4GFUA 1NNYA 4RH9A 2A3KA 1A5YA 4ZN5A 2QEPA 4ZI4A 2F46A 4OHHA 1V3AA 4GS0A 2QCTA 2I6IA 1PTTA 1I9TA 1OETA 2H04A 4OHLA 3AWFA 5K25A 1PTUA 1PXHA 2VEXA 1NWLA 3AWGA 3D9CA 4WTYA 4QUMA 4RI5A 2HC1A 3QKPA 4ICZA 2I3UA 4D3PA 4D3QA 3QCDA 1QXKA 1Q6PA 2F6FA 3H2XA 1D5RA 1XRIA 4HJQA 1OHEA 2HY3A 4JNBA 1FPRA 3S3FA 2QBQA 3QKQA 4S0GA 2AHSA 3ZM2A 3V0GA 1G4US 2G6ZA 4YR8B 1YFOA 4IKCA 3D1QA 1OHCA 3MOZA 3ZMPA 1BZCA 1P15A 2Q47A 1YTNA 1RPMA 1XXPA 4GFVA 4H34A 3O3LA 1OESA 2PQ5A 1Q6JA 3EZZA 4BJOA 1ZZWA 5IBSA 4B04A 4OHEA 2BIJA 3F99A 2QCJA 3BLUA 1NZ7A 3ZMQA 4R0SA 2I5XA 3D44A 3EB1A 3M4UA 4OHDA 1WCHA 2PSZA 3V0HA 1OEOX 3CWEA 2QBSA 3D42A 2CMBA 4GE2A 4WOHA 4KI9A 2ZMMA 1NL9A 2B49A 2HB1A 4BPCA 1VHRA 4RH5A 2OOQA 2B4SA 5EHPA 2H02A 5LXQB 3MMJA 1JLNA 4WU3A 5BZXA 1PH0A 3GXHA 4GRZA 1J4XA 3O4SA 4QAPA 3A5KA 1OEUA 2J16B 1PA9A 3RGOA 3V0EA 4NX8A 2F6VA 1Q6NA
chains in the Genus database with same CATH superfamily
2BGEA 3SMEA 4ZIYA 2NTAA 4OHIA 2GCAA 4GRYA 2VEWA 1T48A 5K9VA 1OHDA 4KYRA 4HJPA 5KAAA 2GC6A 2H03A 1X24A 4YAAA 2A8BA 4C12A 2QDCA 2VEUA 1Q1MA 1W78A 5KA7A 3EMUA 2QDPA 2H4VA 2CM2A 1J6UA 5EHRA 2CM3A 3UAGA 1MKPA 2F71A 2CM7A 4UAGA 3O4UA 2I6MA 2VORA 4BUBA 4HRFA 1PYNA 2I1YA 3S3HA 3ZM6A 1E8CA 5KA0A 3S4EA 1FPZA 2OC3A 2GJTA 2FJNA 2JJDA 2R0BA 2Y96A 1G7GA 2HC2A 1KAVA 5AWXA 1ZCLA 3QCNA 5GTJA 1O5ZA 2B4PA 4Z6BA 2UUPA 3GXGA 1C86A 2BGDA 4GWFA 2WGPA 1EEOA 1BZHA 5I6VA 2F6YA 3F9AA 2VEYA 3QCLA 2CNFA 2FH7A 4PVGA 2H4GA 4GE6A 1JF7A 2CNEA 3NMEA 4RKKA 1WRMA 4JMKA 2CJZA 2MBCA 3V0JA 2GCBA 5KA4A 3QCHA 1XM2A 4I8NA 1G1GA 4HV4A 3BLTA 3ZM3A 4H1OA 3QCIA 3QCZA 1C87A 2IMGA 4CVKA 1XBOA 2F70A 2B4UA 1L8GA 2VTEA 2ESBA 4ZRTA 3I7ZA 4PYHA 4QDIA 1ECVA 1E0DA 3I80A 5KA3A 3QCGA 2B3OA 3PYZA 1G1HA 4QUNA 5KA9A 5A5EA 1EEHA 4GE5A 2X5OA 2I6JA 2AZRA 4DGXA 2F6ZA 2I75A 3OMHA 3B7OA 1NWEA 2BV5A 2UUOA 2PA5A 1GWZA 1ONZA 2PBNA 3V0DA 2F6TA 2CNGA 1YN9A 3QCKA 1YPTA 2XJAA 2I4HA 2C7SA 4Y14A 5KA1A 3BM8A 1G7FA 2HCMA 4JMJA 2B07A 2BZLA 2Q05A 4ERCA 4QBEA 2J17A 3N0AA 1JBWA 2I6PA 4CVLA 1U24A 1LYVA 1ZCKA 3S4OA 4D3RA 2UAGA 3BRHA 2OUDA 4RI4A 4BUCA 4NYHA 5M43A 3ZM1A 1KAKA 1YGRA 5BX1A 4JBCA 2NT7A 3EAXA 1ZC0A 2FJMA 1OEVA 1YGUA 4Y2EA 2RF6A 3O5XA 2YDUA 2CMAA 2J16A 1XXVA 4J51A 1T49A 1BZJA 3U96A 3RZ2A 2NLKA 1LQFA 3CM3A 3QCEA 4KYQA 1GQQA 1YWFA 4DGPA 1LARA 3RO1A 5IBMA 4TVVA 2M3VA 1I57A 1I9SA 2I4EA 3QCJA 3V0IA 1WAXA 2ZN7A 3RGQA 2NZ6A 3SR9A 1P3DA 2G59A 3QCCA 2E0TA 2JFGA 2NT2A 5K23A 2HVLA 4C13A 1PTYA 2HXPA 3MOWA 3N2AA 2PT0A 5K24A 2P4DA 1AAXA 4MBBA 3EU0A 1U25A 2VEVA 4NNDA 4QF5A 2Y1OA 1PA1A 2JFFA 2GC5A 5K22A 1M3GA 3PS5A 2HNQA 2I42A 5BZZA 1NO6A 4WU2A 3D1OA 3O4TA 3LJ8A 4QAHA 2VTDA 4AZ1A 2XPCA 2F00A 1C85A 1G4WR 3AWEA 1QZ0A 2GP0A 2Y2FA 5A5FA 1Q6TA 2NV5A 2B4OA 5MMZB 2I3RA 4R30A 5BUGA 1ONYA 2F6WA 3D1HA 2JFHA 2PI7A 4RHGA 1JBVA 3OLRA 1OEMX 1YTWA 1U26A 2H4KA 2DXPA 2P6XA 1FGSA 5K9WA 1GFYA 1PTVA 3QCFA 1R6HA 5KACA 5KABA 2CNHA 3S3EA 1G1FA 3ZV2A 2I6OA 2CNIA 1FQ1A 2HNPA 3S3KA 1C83A 2SHPA 2CMCA 1Q6MA 2QBRA 3QCBA 1SUGA 1Q6SA 1EENA 2CFVA 3A5JA 3V0FA 5HDEA 1YTSA 4NWFA 4RDDA 3QCMA 2QBPA 2C46A 3F41A 4QBWA 1T4JA 1YZ4A 1GG4A 2CM8A 2GWOA 1L8KA 5KA8A 5J8RA 3F81A 1C84A 2I4GA 3ZM0A 1RXDA 3F9BA 2Y66A 2OZ5A 4NWGA 2QDMA 3I36A 4R0TA 5KA2A 1C88A 5KADA 4GFUA 1NNYA 4RH9A 2Y68A 2A3KA 1A5YA 4ZN5A 2QEPA 3NRSA 4ZI4A 2F46A 4OHHA 1V3AA 4GS0A 2QCTA 2I6IA 1PTTA 1W7KA 1I9TA 1OETA 2H04A 4OHLA 3AWFA 5K25A 1PTUA 1PXHA 2VEXA 1NWLA 3AWGA 3D9CA 4WTYA 4QUMA 4RI5A 2HC1A 3QKPA 4ICZA 2I3UA 4D3PA 3LK7A 4D3QA 3QCDA 1QXKA 1Q6PA 2F6FA 3H2XA 1D5RA 1XRIA 4HJQA 2AM2A 1OHEA 2HY3A 4JNBA 1FPRA 3S3FA 2QBQA 3QKQA 4S0GA 2AHSA 3ZM2A 1P31A 3V0GA 1G4US 2G6ZA 4YR8B 1UAGA 1YFOA 4IKCA 2VOSA 3ZL8A 3D1QA 1OHCA 3MOZA 3ZMPA 1BZCA 1P15A 2Q47A 4CVMA 1YTNA 2WTZA 1RPMA 1XXPA 4GFVA 4H34A 3ZM5A 3O3LA 1OESA 2PQ5A 1Q6JA 3EZZA 4BJOA 1ZZWA 5IBSA 4B04A 4OHEA 1GQYA 2BIJA 3F99A 2AM1A 2QCJA 3BLUA 1NZ7A 3ZMQA 4R0SA 2I5XA 3D44A 3EB1A 3M4UA 4OHDA 1WCHA 2PSZA 3V0HA 1OEOX 3CWEA 2QBSA 3D42A 2CMBA 4GE2A 4WOHA 4KI9A 2ZMMA 1NL9A 2B49A 2HB1A 4BPCA 1VHRA 2WJPA 4RH5A 2OOQA 2B4SA 3HN7A 5EHPA 2H02A 5LXQB 3MMJA 1JLNA 4WU3A 5BZXA 1PH0A 3GXHA 4GRZA 1J4XA 3O4SA 4QAPA 3A5KA 1OEUA 2J16B 1PA9A 3RGOA 3V0EA 3MVNA 2Y67A 4NX8A 2F6VA 1Q6NA
chains in the Genus database with same CATH topology
2BGEA 3SMEA 2NTAA 4OHIA 4GRYA 2VEWA 1T48A 5K9VA 1OHDA 4KYRA 4HJPA 5KAAA 2H03A 1X24A 4YAAA 2A8BA 2QDCA 2VEUA 1Q1MA 5KA7A 3EMUA 2QDPA 2H4VA 2CM2A 5EHRA 2CM3A 1MKPA 2F71A 2CM7A 3O4UA 2I6MA 4HRFA 1PYNA 2I1YA 3S3HA 5KA0A 3S4EA 1FPZA 2OC3A 2GJTA 2FJNA 2JJDA 2R0BA 2Y96A 1G7GA 2HC2A 1KAVA 5AWXA 1ZCLA 3QCNA 5GTJA 2B4PA 4Z6BA 3GXGA 1C86A 2BGDA 4GWFA 2WGPA 1EEOA 1BZHA 5I6VA 2F6YA 3F9AA 2VEYA 3QCLA 2CNFA 2FH7A 4PVGA 2H4GA 4GE6A 1JF7A 2CNEA 3NMEA 4RKKA 1WRMA 4JMKA 2CJZA 2MBCA 3V0JA 5KA4A 3QCHA 1XM2A 4I8NA 1G1GA 3BLTA 3ZM3A 4H1OA 3QCIA 1C87A 2IMGA 1XBOA 2F70A 2B4UA 1L8GA 2ESBA 4ZRTA 3I7ZA 4PYHA 1ECVA 3I80A 5KA3A 3QCGA 2B3OA 1G1HA 4QUNA 5KA9A 4GE5A 2I6JA 2AZRA 4DGXA 2F6ZA 2I75A 3OMHA 3B7OA 1NWEA 2BV5A 2PA5A 1GWZA 1ONZA 2PBNA 3V0DA 2F6TA 2CNGA 1YN9A 3QCKA 1YPTA 2I4HA 2C7SA 4Y14A 5KA1A 3BM8A 1G7FA 2HCMA 4JMJA 2B07A 2BZLA 2Q05A 4ERCA 4QBEA 2J17A 3N0AA 2I6PA 1U24A 1LYVA 1ZCKA 3S4OA 4D3RA 3BRHA 2OUDA 4RI4A 4NYHA 5M43A 3ZM1A 1KAKA 1YGRA 5BX1A 4JBCA 2NT7A 3EAXA 1ZC0A 2FJMA 1OEVA 1YGUA 4Y2EA 2RF6A 3O5XA 2YDUA 2CMAA 2J16A 1XXVA 4J51A 1T49A 1BZJA 3U96A 3RZ2A 2NLKA 1LQFA 3CM3A 3QCEA 4KYQA 1YWFA 4DGPA 1LARA 3RO1A 5IBMA 4TVVA 2M3VA 1I57A 1I9SA 2I4EA 3QCJA 3V0IA 1WAXA 2ZN7A 3RGQA 2NZ6A 3SR9A 2G59A 3QCCA 2E0TA 2NT2A 5K23A 2HVLA 1PTYA 2HXPA 3MOWA 2PT0A 5K24A 2P4DA 1AAXA 4MBBA 3EU0A 1U25A 2VEVA 4NNDA 1PA1A 5K22A 1M3GA 3PS5A 2HNQA 2I42A 5BZZA 1NO6A 4WU2A 3D1OA 3O4TA 3LJ8A 4QAHA 4AZ1A 1C85A 1G4WR 3AWEA 1QZ0A 2GP0A 2Y2FA 1Q6TA 2NV5A 2B4OA 5MMZB 2I3RA 4R30A 5BUGA 1ONYA 2F6WA 3D1HA 2PI7A 4RHGA 3OLRA 1OEMX 1YTWA 1U26A 2H4KA 2DXPA 2P6XA 5K9WA 1GFYA 1PTVA 3QCFA 1R6HA 5KACA 5KABA 2CNHA 3S3EA 1G1FA 3ZV2A 2I6OA 2CNIA 1FQ1A 2HNPA 3S3KA 1C83A 2SHPA 2CMCA 1Q6MA 2QBRA 3QCBA 1SUGA 1Q6SA 1EENA 2CFVA 3A5JA 3V0FA 5HDEA 1YTSA 4NWFA 4RDDA 3QCMA 2QBPA 2C46A 3F41A 4QBWA 1T4JA 1YZ4A 2CM8A 2GWOA 1L8KA 5KA8A 5J8RA 3F81A 1C84A 2I4GA 3ZM0A 1RXDA 3F9BA 2OZ5A 4NWGA 2QDMA 3I36A 4R0TA 5KA2A 1C88A 5KADA 4GFUA 1NNYA 4RH9A 2A3KA 1A5YA 4ZN5A 2QEPA 4ZI4A 2F46A 4OHHA 1V3AA 4GS0A 2QCTA 2I6IA 1PTTA 1I9TA 1OETA 2H04A 4OHLA 3AWFA 5K25A 1PTUA 1PXHA 2VEXA 1NWLA 3AWGA 3D9CA 4WTYA 4QUMA 4RI5A 2HC1A 3QKPA 4ICZA 2I3UA 4D3PA 4D3QA 3QCDA 1QXKA 1Q6PA 2F6FA 3H2XA 1D5RA 1XRIA 4HJQA 1OHEA 2HY3A 4JNBA 1FPRA 3S3FA 2QBQA 3QKQA 4S0GA 2AHSA 3ZM2A 3V0GA 1G4US 2G6ZA 4YR8B 1YFOA 4IKCA 3D1QA 1OHCA 3MOZA 3ZMPA 1BZCA 1P15A 2Q47A 1YTNA 1RPMA 1XXPA 4GFVA 4H34A 3O3LA 1OESA 2PQ5A 1Q6JA 3EZZA 4BJOA 1ZZWA 5IBSA 4B04A 4OHEA 2BIJA 3F99A 2QCJA 3BLUA 1NZ7A 3ZMQA 4R0SA 2I5XA 3D44A 3EB1A 3M4UA 4OHDA 1WCHA 2PSZA 3V0HA 1OEOX 3CWEA 2QBSA 3D42A 2CMBA 4GE2A 4WOHA 4KI9A 2ZMMA 1NL9A 2B49A 2HB1A 4BPCA 1VHRA 4RH5A 2OOQA 2B4SA 5EHPA 2H02A 5LXQB 3MMJA 1JLNA 4WU3A 5BZXA 1PH0A 3GXHA 4GRZA 1J4XA 3O4SA 4QAPA 3A5KA 1OEUA 2J16B 1PA9A 3RGOA 3V0EA 4NX8A 2F6VA 1Q6NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BGE A;  3SME A;  2NTA A;  4OHI A;  4GRY A;  2VEW A;  1T48 A;  5K9V A;  1OHD A;  4KYR A;  4HJP A;  5KAA A;  2H03 A;  1X24 A;  4YAA A;  2A8B A;  2QDC A;  2VEU A;  1Q1M A;  5KA7 A;  3EMU A;  2QDP A;  2H4V A;  2CM2 A;  5EHR A;  2CM3 A;  1MKP A;  2F71 A;  2CM7 A;  3O4U A;  2I6M A;  4HRF A;  1PYN A;  2I1Y A;  3S3H A;  5KA0 A;  3S4E A;  1FPZ A;  2OC3 A;  2GJT A;  2FJN A;  2JJD A;  2R0B A;  2Y96 A;  1G7G A;  2HC2 A;  1KAV A;  5AWX A;  1ZCL A;  3QCN A;  5GTJ A;  2B4P A;  4Z6B A;  3GXG A;  1C86 A;  2BGD A;  4GWF A;  2WGP A;  1EEO A;  1BZH A;  5I6V A;  2F6Y A;  3F9A A;  2VEY A;  3QCL A;  2CNF A;  2FH7 A;  4PVG A;  2H4G A;  4GE6 A;  1JF7 A;  2CNE A;  3NME A;  4RKK A;  1WRM A;  4JMK A;  2CJZ A;  2MBC A;  3V0J A;  5KA4 A;  3QCH A;  1XM2 A;  4I8N A;  1G1G A;  3BLT A;  3ZM3 A;  4H1O A;  3QCI A;  1C87 A;  2IMG A;  1XBO A;  2F70 A;  2B4U A;  1L8G A;  2ESB A;  4ZRT A;  3I7Z A;  4PYH A;  1ECV A;  3I80 A;  5KA3 A;  3QCG A;  2B3O A;  1G1H A;  4QUN A;  5KA9 A;  4GE5 A;  2I6J A;  2AZR A;  4DGX A;  2F6Z A;  2I75 A;  3OMH A;  3B7O A;  1NWE A;  2BV5 A;  2PA5 A;  1GWZ A;  1ONZ A;  2PBN A;  3V0D A;  2F6T A;  2CNG A;  1YN9 A;  3QCK A;  1YPT A;  2I4H A;  2C7S A;  4Y14 A;  5KA1 A;  3BM8 A;  1G7F A;  2HCM A;  4JMJ A;  2B07 A;  2BZL A;  2Q05 A;  4ERC A;  4QBE A;  2J17 A;  3N0A A;  2I6P A;  1U24 A;  1LYV A;  1ZCK A;  3S4O A;  4D3R A;  3BRH A;  2OUD A;  4RI4 A;  4NYH A;  5M43 A;  3ZM1 A;  1KAK A;  1YGR A;  5BX1 A;  4JBC A;  2NT7 A;  3EAX A;  1ZC0 A;  2FJM A;  1OEV A;  1YGU A;  4Y2E A;  2RF6 A;  3O5X A;  2YDU A;  2CMA A;  2J16 A;  1XXV A;  4J51 A;  1T49 A;  1BZJ A;  3U96 A;  3RZ2 A;  2NLK A;  1LQF A;  3CM3 A;  3QCE A;  4KYQ A;  1YWF A;  4DGP A;  1LAR A;  3RO1 A;  5IBM A;  4TVV A;  2M3V A;  1I57 A;  1I9S A;  2I4E A;  3QCJ A;  3V0I A;  1WAX A;  2ZN7 A;  3RGQ A;  2NZ6 A;  3SR9 A;  2G59 A;  3QCC A;  2E0T A;  2NT2 A;  5K23 A;  2HVL A;  1PTY A;  2HXP A;  3MOW A;  2PT0 A;  5K24 A;  2P4D A;  1AAX A;  4MBB A;  3EU0 A;  1U25 A;  2VEV A;  4NND A;  1PA1 A;  5K22 A;  1M3G A;  3PS5 A;  2HNQ A;  2I42 A;  5BZZ A;  1NO6 A;  4WU2 A;  3D1O A;  3O4T A;  3LJ8 A;  4QAH A;  4AZ1 A;  1C85 A;  1G4W R;  3AWE A;  1QZ0 A;  2GP0 A;  2Y2F A;  1Q6T A;  2NV5 A;  2B4O A;  5MMZ B;  2I3R A;  4R30 A;  5BUG A;  1ONY A;  2F6W A;  3D1H A;  2PI7 A;  4RHG A;  3OLR A;  1OEM X;  1YTW A;  1U26 A;  2H4K A;  2DXP A;  2P6X A;  5K9W A;  1GFY A;  1PTV A;  3QCF A;  1R6H A;  5KAC A;  5KAB A;  2CNH A;  3S3E A;  1G1F A;  3ZV2 A;  2I6O A;  2CNI A;  1FQ1 A;  2HNP A;  3S3K A;  1C83 A;  2SHP A;  2CMC A;  1Q6M A;  2QBR A;  3QCB A;  1SUG A;  1Q6S A;  1EEN A;  2CFV A;  3A5J A;  3V0F A;  5HDE A;  1YTS A;  4NWF A;  4RDD A;  3QCM A;  2QBP A;  2C46 A;  3F41 A;  4QBW A;  1T4J A;  1YZ4 A;  2CM8 A;  2GWO A;  1L8K A;  5KA8 A;  5J8R A;  3F81 A;  1C84 A;  2I4G A;  3ZM0 A;  1RXD A;  3F9B A;  2OZ5 A;  4NWG A;  2QDM A;  3I36 A;  4R0T A;  5KA2 A;  1C88 A;  5KAD A;  4GFU A;  1NNY A;  4RH9 A;  2A3K A;  1A5Y A;  4ZN5 A;  2QEP A;  4ZI4 A;  2F46 A;  4OHH A;  1V3A A;  4GS0 A;  2QCT A;  2I6I A;  1PTT A;  1I9T A;  1OET A;  2H04 A;  4OHL A;  3AWF A;  5K25 A;  1PTU A;  1PXH A;  2VEX A;  1NWL A;  3AWG A;  3D9C A;  4WTY A;  4QUM A;  4RI5 A;  2HC1 A;  3QKP A;  4ICZ A;  2I3U A;  4D3P A;  4D3Q A;  3QCD A;  1QXK A;  1Q6P A;  2F6F A;  3H2X A;  1D5R A;  1XRI A;  4HJQ A;  1OHE A;  2HY3 A;  4JNB A;  1FPR A;  3S3F A;  2QBQ A;  3QKQ A;  4S0G A;  2AHS A;  3ZM2 A;  3V0G A;  1G4U S;  2G6Z A;  4YR8 B;  1YFO A;  4IKC A;  3D1Q A;  1OHC A;  3MOZ A;  3ZMP A;  1BZC A;  1P15 A;  2Q47 A;  1YTN A;  1RPM A;  1XXP A;  4GFV A;  4H34 A;  3O3L A;  1OES A;  2PQ5 A;  1Q6J A;  3EZZ A;  4BJO A;  1ZZW A;  5IBS A;  4B04 A;  4OHE A;  2BIJ A;  3F99 A;  2QCJ A;  3BLU A;  1NZ7 A;  3ZMQ A;  4R0S A;  2I5X A;  3D44 A;  3EB1 A;  3M4U A;  4OHD A;  1WCH A;  2PSZ A;  3V0H A;  1OEO X;  3CWE A;  2QBS A;  3D42 A;  2CMB A;  4GE2 A;  4WOH A;  4KI9 A;  2ZMM A;  1NL9 A;  2B49 A;  2HB1 A;  4BPC A;  1VHR A;  4RH5 A;  2OOQ A;  2B4S A;  5EHP A;  2H02 A;  5LXQ B;  3MMJ A;  1JLN A;  4WU3 A;  5BZX A;  1PH0 A;  3GXH A;  4GRZ A;  1J4X A;  3O4S A;  4QAP A;  3A5K A;  1OEU A;  2J16 B;  1PA9 A;  3RGO A;  3V0E A;  4NX8 A;  2F6V A;  1Q6N A; 
#chains in the Genus database with same CATH topology
 2BGE A;  3SME A;  4ZIY A;  2NTA A;  4OHI A;  2GCA A;  4GRY A;  2VEW A;  1T48 A;  5K9V A;  1OHD A;  4KYR A;  4HJP A;  5KAA A;  2GC6 A;  2H03 A;  1X24 A;  4YAA A;  2A8B A;  4C12 A;  2QDC A;  2VEU A;  1Q1M A;  1W78 A;  5KA7 A;  3EMU A;  2QDP A;  2H4V A;  2CM2 A;  1J6U A;  5EHR A;  2CM3 A;  3UAG A;  1MKP A;  2F71 A;  2CM7 A;  4UAG A;  3O4U A;  2I6M A;  2VOR A;  4BUB A;  4HRF A;  1PYN A;  2I1Y A;  3S3H A;  3ZM6 A;  1E8C A;  5KA0 A;  3S4E A;  1FPZ A;  2OC3 A;  2GJT A;  2FJN A;  2JJD A;  2R0B A;  2Y96 A;  1G7G A;  2HC2 A;  1KAV A;  5AWX A;  1ZCL A;  3QCN A;  5GTJ A;  1O5Z A;  2B4P A;  4Z6B A;  2UUP A;  3GXG A;  1C86 A;  2BGD A;  4GWF A;  2WGP A;  1EEO A;  1BZH A;  5I6V A;  2F6Y A;  3F9A A;  2VEY A;  3QCL A;  2CNF A;  2FH7 A;  4PVG A;  2H4G A;  4GE6 A;  1JF7 A;  2CNE A;  3NME A;  4RKK A;  1WRM A;  4JMK A;  2CJZ A;  2MBC A;  3V0J A;  2GCB A;  5KA4 A;  3QCH A;  1XM2 A;  4I8N A;  1G1G A;  4HV4 A;  3BLT A;  3ZM3 A;  4H1O A;  3QCI A;  3QCZ A;  1C87 A;  2IMG A;  4CVK A;  1XBO A;  2F70 A;  2B4U A;  1L8G A;  2VTE A;  2ESB A;  4ZRT A;  3I7Z A;  4PYH A;  4QDI A;  1ECV A;  1E0D A;  3I80 A;  5KA3 A;  3QCG A;  2B3O A;  3PYZ A;  1G1H A;  4QUN A;  5KA9 A;  5A5E A;  1EEH A;  4GE5 A;  2X5O A;  2I6J A;  2AZR A;  4DGX A;  2F6Z A;  2I75 A;  3OMH A;  3B7O A;  1NWE A;  2BV5 A;  2UUO A;  2PA5 A;  1GWZ A;  1ONZ A;  2PBN A;  3V0D A;  2F6T A;  2CNG A;  1YN9 A;  3QCK A;  1YPT A;  2XJA A;  2I4H A;  2C7S A;  4Y14 A;  5KA1 A;  3BM8 A;  1G7F A;  2HCM A;  4JMJ A;  2B07 A;  2BZL A;  2Q05 A;  4ERC A;  4QBE A;  2J17 A;  3N0A A;  1JBW A;  2I6P A;  4CVL A;  1U24 A;  1LYV A;  1ZCK A;  3S4O A;  4D3R A;  2UAG A;  3BRH A;  2OUD A;  4RI4 A;  4BUC A;  4NYH A;  5M43 A;  3ZM1 A;  1KAK A;  1YGR A;  5BX1 A;  4JBC A;  2NT7 A;  3EAX A;  1ZC0 A;  2FJM A;  1OEV A;  1YGU A;  4Y2E A;  2RF6 A;  3O5X A;  2YDU A;  2CMA A;  2J16 A;  1XXV A;  4J51 A;  1T49 A;  1BZJ A;  3U96 A;  3RZ2 A;  2NLK A;  1LQF A;  3CM3 A;  3QCE A;  4KYQ A;  1GQQ A;  1YWF A;  4DGP A;  1LAR A;  3RO1 A;  5IBM A;  4TVV A;  2M3V A;  1I57 A;  1I9S A;  2I4E A;  3QCJ A;  3V0I A;  1WAX A;  2ZN7 A;  3RGQ A;  2NZ6 A;  3SR9 A;  1P3D A;  2G59 A;  3QCC A;  2E0T A;  2JFG A;  2NT2 A;  5K23 A;  2HVL A;  4C13 A;  1PTY A;  2HXP A;  3MOW A;  3N2A A;  2PT0 A;  5K24 A;  2P4D A;  1AAX A;  4MBB A;  3EU0 A;  1U25 A;  2VEV A;  4NND A;  4QF5 A;  2Y1O A;  1PA1 A;  2JFF A;  2GC5 A;  5K22 A;  1M3G A;  3PS5 A;  2HNQ A;  2I42 A;  5BZZ A;  1NO6 A;  4WU2 A;  3D1O A;  3O4T A;  3LJ8 A;  4QAH A;  2VTD A;  4AZ1 A;  2XPC A;  2F00 A;  1C85 A;  1G4W R;  3AWE A;  1QZ0 A;  2GP0 A;  2Y2F A;  5A5F A;  1Q6T A;  2NV5 A;  2B4O A;  5MMZ B;  2I3R A;  4R30 A;  5BUG A;  1ONY A;  2F6W A;  3D1H A;  2JFH A;  2PI7 A;  4RHG A;  1JBV A;  3OLR A;  1OEM X;  1YTW A;  1U26 A;  2H4K A;  2DXP A;  2P6X A;  1FGS A;  5K9W A;  1GFY A;  1PTV A;  3QCF A;  1R6H A;  5KAC A;  5KAB A;  2CNH A;  3S3E A;  1G1F A;  3ZV2 A;  2I6O A;  2CNI A;  1FQ1 A;  2HNP A;  3S3K A;  1C83 A;  2SHP A;  2CMC A;  1Q6M A;  2QBR A;  3QCB A;  1SUG A;  1Q6S A;  1EEN A;  2CFV A;  3A5J A;  3V0F A;  5HDE A;  1YTS A;  4NWF A;  4RDD A;  3QCM A;  2QBP A;  2C46 A;  3F41 A;  4QBW A;  1T4J A;  1YZ4 A;  1GG4 A;  2CM8 A;  2GWO A;  1L8K A;  5KA8 A;  5J8R A;  3F81 A;  1C84 A;  2I4G A;  3ZM0 A;  1RXD A;  3F9B A;  2Y66 A;  2OZ5 A;  4NWG A;  2QDM A;  3I36 A;  4R0T A;  5KA2 A;  1C88 A;  5KAD A;  4GFU A;  1NNY A;  4RH9 A;  2Y68 A;  2A3K A;  1A5Y A;  4ZN5 A;  2QEP A;  3NRS A;  4ZI4 A;  2F46 A;  4OHH A;  1V3A A;  4GS0 A;  2QCT A;  2I6I A;  1PTT A;  1W7K A;  1I9T A;  1OET A;  2H04 A;  4OHL A;  3AWF A;  5K25 A;  1PTU A;  1PXH A;  2VEX A;  1NWL A;  3AWG A;  3D9C A;  4WTY A;  4QUM A;  4RI5 A;  2HC1 A;  3QKP A;  4ICZ A;  2I3U A;  4D3P A;  3LK7 A;  4D3Q A;  3QCD A;  1QXK A;  1Q6P A;  2F6F A;  3H2X A;  1D5R A;  1XRI A;  4HJQ A;  2AM2 A;  1OHE A;  2HY3 A;  4JNB A;  1FPR A;  3S3F A;  2QBQ A;  3QKQ A;  4S0G A;  2AHS A;  3ZM2 A;  1P31 A;  3V0G A;  1G4U S;  2G6Z A;  4YR8 B;  1UAG A;  1YFO A;  4IKC A;  2VOS A;  3ZL8 A;  3D1Q A;  1OHC A;  3MOZ A;  3ZMP A;  1BZC A;  1P15 A;  2Q47 A;  4CVM A;  1YTN A;  2WTZ A;  1RPM A;  1XXP A;  4GFV A;  4H34 A;  3ZM5 A;  3O3L A;  1OES A;  2PQ5 A;  1Q6J A;  3EZZ A;  4BJO A;  1ZZW A;  5IBS A;  4B04 A;  4OHE A;  1GQY A;  2BIJ A;  3F99 A;  2AM1 A;  2QCJ A;  3BLU A;  1NZ7 A;  3ZMQ A;  4R0S A;  2I5X A;  3D44 A;  3EB1 A;  3M4U A;  4OHD A;  1WCH A;  2PSZ A;  3V0H A;  1OEO X;  3CWE A;  2QBS A;  3D42 A;  2CMB A;  4GE2 A;  4WOH A;  4KI9 A;  2ZMM A;  1NL9 A;  2B49 A;  2HB1 A;  4BPC A;  1VHR A;  2WJP A;  4RH5 A;  2OOQ A;  2B4S A;  3HN7 A;  5EHP A;  2H02 A;  5LXQ B;  3MMJ A;  1JLN A;  4WU3 A;  5BZX A;  1PH0 A;  3GXH A;  4GRZ A;  1J4X A;  3O4S A;  4QAP A;  3A5K A;  1OEU A;  2J16 B;  1PA9 A;  3RGO A;  3V0E A;  3MVN A;  2Y67 A;  4NX8 A;  2F6V A;  1Q6N A; 
#chains in the Genus database with same CATH homology
 2BGE A;  3SME A;  2NTA A;  4OHI A;  4GRY A;  2VEW A;  1T48 A;  5K9V A;  1OHD A;  4KYR A;  4HJP A;  5KAA A;  2H03 A;  1X24 A;  4YAA A;  2A8B A;  2QDC A;  2VEU A;  1Q1M A;  5KA7 A;  3EMU A;  2QDP A;  2H4V A;  2CM2 A;  5EHR A;  2CM3 A;  1MKP A;  2F71 A;  2CM7 A;  3O4U A;  2I6M A;  4HRF A;  1PYN A;  2I1Y A;  3S3H A;  5KA0 A;  3S4E A;  1FPZ A;  2OC3 A;  2GJT A;  2FJN A;  2JJD A;  2R0B A;  2Y96 A;  1G7G A;  2HC2 A;  1KAV A;  5AWX A;  1ZCL A;  3QCN A;  5GTJ A;  2B4P A;  4Z6B A;  3GXG A;  1C86 A;  2BGD A;  4GWF A;  2WGP A;  1EEO A;  1BZH A;  5I6V A;  2F6Y A;  3F9A A;  2VEY A;  3QCL A;  2CNF A;  2FH7 A;  4PVG A;  2H4G A;  4GE6 A;  1JF7 A;  2CNE A;  3NME A;  4RKK A;  1WRM A;  4JMK A;  2CJZ A;  2MBC A;  3V0J A;  5KA4 A;  3QCH A;  1XM2 A;  4I8N A;  1G1G A;  3BLT A;  3ZM3 A;  4H1O A;  3QCI A;  1C87 A;  2IMG A;  1XBO A;  2F70 A;  2B4U A;  1L8G A;  2ESB A;  4ZRT A;  3I7Z A;  4PYH A;  1ECV A;  3I80 A;  5KA3 A;  3QCG A;  2B3O A;  1G1H A;  4QUN A;  5KA9 A;  4GE5 A;  2I6J A;  2AZR A;  4DGX A;  2F6Z A;  2I75 A;  3OMH A;  3B7O A;  1NWE A;  2BV5 A;  2PA5 A;  1GWZ A;  1ONZ A;  2PBN A;  3V0D A;  2F6T A;  2CNG A;  1YN9 A;  3QCK A;  1YPT A;  2I4H A;  2C7S A;  4Y14 A;  5KA1 A;  3BM8 A;  1G7F A;  2HCM A;  4JMJ A;  2B07 A;  2BZL A;  2Q05 A;  4ERC A;  4QBE A;  2J17 A;  3N0A A;  2I6P A;  1U24 A;  1LYV A;  1ZCK A;  3S4O A;  4D3R A;  3BRH A;  2OUD A;  4RI4 A;  4NYH A;  5M43 A;  3ZM1 A;  1KAK A;  1YGR A;  5BX1 A;  4JBC A;  2NT7 A;  3EAX A;  1ZC0 A;  2FJM A;  1OEV A;  1YGU A;  4Y2E A;  2RF6 A;  3O5X A;  2YDU A;  2CMA A;  2J16 A;  1XXV A;  4J51 A;  1T49 A;  1BZJ A;  3U96 A;  3RZ2 A;  2NLK A;  1LQF A;  3CM3 A;  3QCE A;  4KYQ A;  1YWF A;  4DGP A;  1LAR A;  3RO1 A;  5IBM A;  4TVV A;  2M3V A;  1I57 A;  1I9S A;  2I4E A;  3QCJ A;  3V0I A;  1WAX A;  2ZN7 A;  3RGQ A;  2NZ6 A;  3SR9 A;  2G59 A;  3QCC A;  2E0T A;  2NT2 A;  5K23 A;  2HVL A;  1PTY A;  2HXP A;  3MOW A;  2PT0 A;  5K24 A;  2P4D A;  1AAX A;  4MBB A;  3EU0 A;  1U25 A;  2VEV A;  4NND A;  1PA1 A;  5K22 A;  1M3G A;  3PS5 A;  2HNQ A;  2I42 A;  5BZZ A;  1NO6 A;  4WU2 A;  3D1O A;  3O4T A;  3LJ8 A;  4QAH A;  4AZ1 A;  1C85 A;  1G4W R;  3AWE A;  1QZ0 A;  2GP0 A;  2Y2F A;  1Q6T A;  2NV5 A;  2B4O A;  5MMZ B;  2I3R A;  4R30 A;  5BUG A;  1ONY A;  2F6W A;  3D1H A;  2PI7 A;  4RHG A;  3OLR A;  1OEM X;  1YTW A;  1U26 A;  2H4K A;  2DXP A;  2P6X A;  5K9W A;  1GFY A;  1PTV A;  3QCF A;  1R6H A;  5KAC A;  5KAB A;  2CNH A;  3S3E A;  1G1F A;  3ZV2 A;  2I6O A;  2CNI A;  1FQ1 A;  2HNP A;  3S3K A;  1C83 A;  2SHP A;  2CMC A;  1Q6M A;  2QBR A;  3QCB A;  1SUG A;  1Q6S A;  1EEN A;  2CFV A;  3A5J A;  3V0F A;  5HDE A;  1YTS A;  4NWF A;  4RDD A;  3QCM A;  2QBP A;  2C46 A;  3F41 A;  4QBW A;  1T4J A;  1YZ4 A;  2CM8 A;  2GWO A;  1L8K A;  5KA8 A;  5J8R A;  3F81 A;  1C84 A;  2I4G A;  3ZM0 A;  1RXD A;  3F9B A;  2OZ5 A;  4NWG A;  2QDM A;  3I36 A;  4R0T A;  5KA2 A;  1C88 A;  5KAD A;  4GFU A;  1NNY A;  4RH9 A;  2A3K A;  1A5Y A;  4ZN5 A;  2QEP A;  4ZI4 A;  2F46 A;  4OHH A;  1V3A A;  4GS0 A;  2QCT A;  2I6I A;  1PTT A;  1I9T A;  1OET A;  2H04 A;  4OHL A;  3AWF A;  5K25 A;  1PTU A;  1PXH A;  2VEX A;  1NWL A;  3AWG A;  3D9C A;  4WTY A;  4QUM A;  4RI5 A;  2HC1 A;  3QKP A;  4ICZ A;  2I3U A;  4D3P A;  4D3Q A;  3QCD A;  1QXK A;  1Q6P A;  2F6F A;  3H2X A;  1D5R A;  1XRI A;  4HJQ A;  1OHE A;  2HY3 A;  4JNB A;  1FPR A;  3S3F A;  2QBQ A;  3QKQ A;  4S0G A;  2AHS A;  3ZM2 A;  3V0G A;  1G4U S;  2G6Z A;  4YR8 B;  1YFO A;  4IKC A;  3D1Q A;  1OHC A;  3MOZ A;  3ZMP A;  1BZC A;  1P15 A;  2Q47 A;  1YTN A;  1RPM A;  1XXP A;  4GFV A;  4H34 A;  3O3L A;  1OES A;  2PQ5 A;  1Q6J A;  3EZZ A;  4BJO A;  1ZZW A;  5IBS A;  4B04 A;  4OHE A;  2BIJ A;  3F99 A;  2QCJ A;  3BLU A;  1NZ7 A;  3ZMQ A;  4R0S A;  2I5X A;  3D44 A;  3EB1 A;  3M4U A;  4OHD A;  1WCH A;  2PSZ A;  3V0H A;  1OEO X;  3CWE A;  2QBS A;  3D42 A;  2CMB A;  4GE2 A;  4WOH A;  4KI9 A;  2ZMM A;  1NL9 A;  2B49 A;  2HB1 A;  4BPC A;  1VHR A;  4RH5 A;  2OOQ A;  2B4S A;  5EHP A;  2H02 A;  5LXQ B;  3MMJ A;  1JLN A;  4WU3 A;  5BZX A;  1PH0 A;  3GXH A;  4GRZ A;  1J4X A;  3O4S A;  4QAP A;  3A5K A;  1OEU A;  2J16 B;  1PA9 A;  3RGO A;  3V0E A;  4NX8 A;  2F6V A;  1Q6N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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