The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
169
|
sequence length |
660
|
structure length |
628
|
Chain Sequence |
GTLIRVTPEQPTHAVCVLGTLTQLDICSSAPETSFSINASPGVVVDITWPLDPGVEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCADITRTGKQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHAGTNVRRKPFSFKWWNMVP
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural basis for Ca(2+)-induced activation of human PAD4
pubmed doi rcsb |
| molecule keywords |
Protein-arginine deiminase type IV
|
| source organism |
Homo sapiens
|
| molecule tags |
Hydrolase
|
| total genus |
169
|
| structure length |
628
|
| sequence length |
660
|
| ec nomenclature |
ec
3.5.3.15: Protein-arginine deiminase. |
| pdb deposition date | 2004-05-12 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF03068 | PAD | Protein-arginine deiminase (PAD) |
| A | PF08526 | PAD_N | Protein-arginine deiminase (PAD) N-terminal domain |
| A | PF08527 | PAD_M | Protein-arginine deiminase (PAD) middle domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Sandwich | Immunoglobulin-like | Protein-arginine deiminase, central domain | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulin-like | ||
| Alpha Beta | 5-stranded Propeller | L-arginine/glycine Amidinotransferase; Chain A | L-arginine/glycine Amidinotransferase; Chain A |
