1WEFA

Catalytic domain of muty from escherichia coli k20a mutant
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRATLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords A/G-specific adenine glycosylase
total genus 71
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2004-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1wefA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1wefA01
1KO9A 4E9HA 3IHOA 1LMZA 4YPHA 1PU8A 3F0ZA 1HU0A 1KG4A 3CWTA 3F10A 4HSBA 1NKUA 1KG2A 4E9GA 2NOBA 4B24A 4B21A 1N3AA 2OFKA 3CWSA 5CHZA 1KQJA 4OFEA 1PU6A 1WEGA 1P59A 3N0UA 1PU7A 3I0XA 1YQRA 3D4VA 1N3CA 1MPGA 1WEFA 3OGDA 1ORPA 1PVSA 1VRLA 1KG5A 1RRQA 3G0QA 1MUNA 5KN9A 2JHJA 2NOLA 2JG6A 5KN8A 4AI4A 2H56A 1LWVA 3CVTA 2NOIA 1KG7A 4PIIA 1MUDA 1MUYA 1M3HA 3FSPA 1KG6A 1LWYA 4E9FA 3I0WA 4AIAA 3CVSA 3CWAA 4YOQA 2I5WA 3IH7A 2NOZA 3KTUA 3OH6A 2NOEA 1P7MA 1XQPA 3FHGA 2NOHA 1LWWA 3KNTA 1M3QA 1YQMA 2ABKA 2OFIA 4EW4A 4EJZA 2YG9A 3CW7A 4EA5A 2JHNA 5AN4A 3OH9A 2YG8A 1EBMA 4B23A 3S6IA 3FHFA 4B22A 2XHIA 5DPKA 4YPRA 4UNFA 1KEAA 4OFHA 4AI5A 4DK9A 1FN7A 1XQOA 4OFAA 1RRSA 1KG3A 1YQKA 1XG7A 4E9EA 4EVVA 4EA4A 1DIZA 4EJYA 4UOBA 1YQLA 1ORNA 1NGNA 2NOFA 3CWUA 3N5NX 4EW0A 1N39A 1WEIA
chains in the Genus database with same CATH superfamily
1KO9A 4E9HA 3OYDA 3IHOA 4BDYA 1LMZA 4YPHA 1PU8A 3F0ZA 1HU0A 1KG4A 3CWTA 3L2RA 3F10A 4HSBA 1NKUA 2W04A 1KG2A 4E9GA 2NOBA 4B24A 4BDZA 3OS1A 4B21A 2OFKA 2W03A 3L2WA 5CHZA 1N3AA 3CWSA 1KQJA 4OFEA 1PU6A 4BE1A 3OYCA 1WEGA 1P59A 3N0UA 1PU7A 3I0XA 3NNQA 1YQRA 3D4VA 1N3CA 1MPGA 5FRMA 1WEFA 3OGDA 1ORPA 1PVSA 1VRLA 1KG5A 1U84A 1RRQA 3G0QA 1MUNA 3OYNA 3R2XC 5KN9A 4BE0A 2JHJA 3L2QA 4BACA 4IKFA 2NOLA 2JG6A 3OYFA 5KN8A 4AI4A 4E7HA 2H56A 3S3NA 3OYIA 5FROA 1LWVA 3CVTA 2NOIA 1KG7A 4BE2A 4PIIA 3OYGA 1MUDA 1MUYA 1M3HA 3FSPA 4NZGA 4ZTJA 3OS2A 1KG6A 1LWYA 3OYJA 4E7JA 4E9FA 3I0WA 4AIAA 3OYMA 3CVSA 3OYKA 3CWAA 4YOQA 3S3MA 4E7LA 2I5WA 3IH7A 2NOZA 3KTUA 3S3OA 3OH6A 2NOEA 1P7MA 1XQPA 5FRNA 3FHGA 3OS0A 2NOHA 3OYAA 1LWWA 4E7IA 3KNTA 1M3QA 3OYHA 3L2UA 1YQMA 2ABKA 2OFIA 4EW4A 4EJZA 2YG9A 3CW7A 2JPSA 4EA5A 2JHNA 5AN4A 3OH9A 2YG8A 1EBMA 4B23A 3S6IA 3FHFA 4B22A 2XHIA 3VW4A 5DPKA 4YPRA 3LCNA 4UNFA 4E7KA 1KEAA 4OFHA 4AI5A 3OYBA 4DK9A 1FN7A 3OYEA 1XQOA 4OFAA 1RRSA 3OY9A 1KG3A 1YQKA 1XG7A 4E9EA 4EVVA 4EA4A 4ZTFA 1DIZA 4EJYA 4UOBA 1YQLA 1ORNA 1NGNA 2NOFA 3CWUA 3N5NX 3OYLA 4EW0A 3L2VA 1N39A 2V75A 1WEIA
chains in the Genus database with same CATH topology
1KO9A 4E9HA 3IHOA 1LMZA 4YPHA 1PU8A 3F0ZA 1HU0A 1KG4A 3CWTA 3F10A 4HSBA 1NKUA 1KG2A 4E9GA 2NOBA 4B24A 4B21A 1N3AA 2OFKA 3CWSA 5CHZA 1KQJA 4OFEA 1PU6A 1WEGA 1P59A 3N0UA 1PU7A 3I0XA 1YQRA 3D4VA 1N3CA 1MPGA 1WEFA 3OGDA 1ORPA 1PVSA 1VRLA 1KG5A 1RRQA 3G0QA 1MUNA 5KN9A 2JHJA 2NOLA 2JG6A 5KN8A 4AI4A 2H56A 1LWVA 3CVTA 2NOIA 1KG7A 4PIIA 1MUDA 1MUYA 1M3HA 3FSPA 1KG6A 1LWYA 4E9FA 3I0WA 4AIAA 3CVSA 3CWAA 4YOQA 2I5WA 3IH7A 2NOZA 3KTUA 3OH6A 2NOEA 1P7MA 1XQPA 3FHGA 2NOHA 1LWWA 3KNTA 1M3QA 1YQMA 2ABKA 2OFIA 4EW4A 4EJZA 2YG9A 3CW7A 4EA5A 2JHNA 5AN4A 3OH9A 2YG8A 1EBMA 4B23A 3S6IA 3FHFA 4B22A 2XHIA 5DPKA 4YPRA 4UNFA 1KEAA 4OFHA 4AI5A 4DK9A 1FN7A 1XQOA 4OFAA 1RRSA 1KG3A 1YQKA 1XG7A 4E9EA 4EVVA 4EA4A 1DIZA 4EJYA 4UOBA 1YQLA 1ORNA 1NGNA 2NOFA 3CWUA 3N5NX 4EW0A 1N39A 1WEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KO9 A;  4E9H A;  3IHO A;  1LMZ A;  4YPH A;  1PU8 A;  3F0Z A;  1HU0 A;  1KG4 A;  3CWT A;  3F10 A;  4HSB A;  1NKU A;  1KG2 A;  4E9G A;  2NOB A;  4B24 A;  4B21 A;  1N3A A;  2OFK A;  3CWS A;  5CHZ A;  1KQJ A;  4OFE A;  1PU6 A;  1WEG A;  1P59 A;  3N0U A;  1PU7 A;  3I0X A;  1YQR A;  3D4V A;  1N3C A;  1MPG A;  1WEF A;  3OGD A;  1ORP A;  1PVS A;  1VRL A;  1KG5 A;  1RRQ A;  3G0Q A;  1MUN A;  5KN9 A;  2JHJ A;  2NOL A;  2JG6 A;  5KN8 A;  4AI4 A;  2H56 A;  1LWV A;  3CVT A;  2NOI A;  1KG7 A;  4PII A;  1MUD A;  1MUY A;  1M3H A;  3FSP A;  1KG6 A;  1LWY A;  4E9F A;  3I0W A;  4AIA A;  3CVS A;  3CWA A;  4YOQ A;  2I5W A;  3IH7 A;  2NOZ A;  3KTU A;  3OH6 A;  2NOE A;  1P7M A;  1XQP A;  3FHG A;  2NOH A;  1LWW A;  3KNT A;  1M3Q A;  1YQM A;  2ABK A;  2OFI A;  4EW4 A;  4EJZ A;  2YG9 A;  3CW7 A;  4EA5 A;  2JHN A;  5AN4 A;  3OH9 A;  2YG8 A;  1EBM A;  4B23 A;  3S6I A;  3FHF A;  4B22 A;  2XHI A;  5DPK A;  4YPR A;  4UNF A;  1KEA A;  4OFH A;  4AI5 A;  4DK9 A;  1FN7 A;  1XQO A;  4OFA A;  1RRS A;  1KG3 A;  1YQK A;  1XG7 A;  4E9E A;  4EVV A;  4EA4 A;  1DIZ A;  4EJY A;  4UOB A;  1YQL A;  1ORN A;  1NGN A;  2NOF A;  3CWU A;  3N5N X;  4EW0 A;  1N39 A;  1WEI A; 
#chains in the Genus database with same CATH topology
 1KO9 A;  4E9H A;  3OYD A;  3IHO A;  4BDY A;  1LMZ A;  4YPH A;  1PU8 A;  3F0Z A;  1HU0 A;  1KG4 A;  3CWT A;  3L2R A;  3F10 A;  4HSB A;  1NKU A;  2W04 A;  1KG2 A;  4E9G A;  2NOB A;  4B24 A;  4BDZ A;  3OS1 A;  4B21 A;  2OFK A;  2W03 A;  3L2W A;  5CHZ A;  1N3A A;  3CWS A;  1KQJ A;  4OFE A;  1PU6 A;  4BE1 A;  3OYC A;  1WEG A;  1P59 A;  3N0U A;  1PU7 A;  3I0X A;  3NNQ A;  1YQR A;  3D4V A;  1N3C A;  1MPG A;  5FRM A;  1WEF A;  3OGD A;  1ORP A;  1PVS A;  1VRL A;  1KG5 A;  1U84 A;  1RRQ A;  3G0Q A;  1MUN A;  3OYN A;  3R2X C;  5KN9 A;  4BE0 A;  2JHJ A;  3L2Q A;  4BAC A;  4IKF A;  2NOL A;  2JG6 A;  3OYF A;  5KN8 A;  4AI4 A;  4E7H A;  2H56 A;  3S3N A;  3OYI A;  5FRO A;  1LWV A;  3CVT A;  2NOI A;  1KG7 A;  4BE2 A;  4PII A;  3OYG A;  1MUD A;  1MUY A;  1M3H A;  3FSP A;  4NZG A;  4ZTJ A;  3OS2 A;  1KG6 A;  1LWY A;  3OYJ A;  4E7J A;  4E9F A;  3I0W A;  4AIA A;  3OYM A;  3CVS A;  3OYK A;  3CWA A;  4YOQ A;  3S3M A;  4E7L A;  2I5W A;  3IH7 A;  2NOZ A;  3KTU A;  3S3O A;  3OH6 A;  2NOE A;  1P7M A;  1XQP A;  5FRN A;  3FHG A;  3OS0 A;  2NOH A;  3OYA A;  1LWW A;  4E7I A;  3KNT A;  1M3Q A;  3OYH A;  3L2U A;  1YQM A;  2ABK A;  2OFI A;  4EW4 A;  4EJZ A;  2YG9 A;  3CW7 A;  2JPS A;  4EA5 A;  2JHN A;  5AN4 A;  3OH9 A;  2YG8 A;  1EBM A;  4B23 A;  3S6I A;  3FHF A;  4B22 A;  2XHI A;  3VW4 A;  5DPK A;  4YPR A;  3LCN A;  4UNF A;  4E7K A;  1KEA A;  4OFH A;  4AI5 A;  3OYB A;  4DK9 A;  1FN7 A;  3OYE A;  1XQO A;  4OFA A;  1RRS A;  3OY9 A;  1KG3 A;  1YQK A;  1XG7 A;  4E9E A;  4EVV A;  4EA4 A;  4ZTF A;  1DIZ A;  4EJY A;  4UOB A;  1YQL A;  1ORN A;  1NGN A;  2NOF A;  3CWU A;  3N5N X;  3OYL A;  4EW0 A;  3L2V A;  1N39 A;  2V75 A;  1WEI A; 
#chains in the Genus database with same CATH homology
 1KO9 A;  4E9H A;  3IHO A;  1LMZ A;  4YPH A;  1PU8 A;  3F0Z A;  1HU0 A;  1KG4 A;  3CWT A;  3F10 A;  4HSB A;  1NKU A;  1KG2 A;  4E9G A;  2NOB A;  4B24 A;  4B21 A;  1N3A A;  2OFK A;  3CWS A;  5CHZ A;  1KQJ A;  4OFE A;  1PU6 A;  1WEG A;  1P59 A;  3N0U A;  1PU7 A;  3I0X A;  1YQR A;  3D4V A;  1N3C A;  1MPG A;  1WEF A;  3OGD A;  1ORP A;  1PVS A;  1VRL A;  1KG5 A;  1RRQ A;  3G0Q A;  1MUN A;  5KN9 A;  2JHJ A;  2NOL A;  2JG6 A;  5KN8 A;  4AI4 A;  2H56 A;  1LWV A;  3CVT A;  2NOI A;  1KG7 A;  4PII A;  1MUD A;  1MUY A;  1M3H A;  3FSP A;  1KG6 A;  1LWY A;  4E9F A;  3I0W A;  4AIA A;  3CVS A;  3CWA A;  4YOQ A;  2I5W A;  3IH7 A;  2NOZ A;  3KTU A;  3OH6 A;  2NOE A;  1P7M A;  1XQP A;  3FHG A;  2NOH A;  1LWW A;  3KNT A;  1M3Q A;  1YQM A;  2ABK A;  2OFI A;  4EW4 A;  4EJZ A;  2YG9 A;  3CW7 A;  4EA5 A;  2JHN A;  5AN4 A;  3OH9 A;  2YG8 A;  1EBM A;  4B23 A;  3S6I A;  3FHF A;  4B22 A;  2XHI A;  5DPK A;  4YPR A;  4UNF A;  1KEA A;  4OFH A;  4AI5 A;  4DK9 A;  1FN7 A;  1XQO A;  4OFA A;  1RRS A;  1KG3 A;  1YQK A;  1XG7 A;  4E9E A;  4EVV A;  4EA4 A;  1DIZ A;  4EJY A;  4UOB A;  1YQL A;  1ORN A;  1NGN A;  2NOF A;  3CWU A;  3N5N X;  4EW0 A;  1N39 A;  1WEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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