1WEFA

Catalytic domain of muty from escherichia coli k20a mutant
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRATLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 71
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2004-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1wefA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1wefA01
4AI4A 4OFEA 4YPHA 1N39A 3FHFA 5KN8A 1DIZA 3CWTA 3IHOA 2YG9A 2NOHA 2NOBA 2NOLA 3OH9A 1NGNA 3KTUA 3D4VA 1PU6A 3I0XA 3CVSA 1M3QA 3FSPA 1MUYA 2NOIA 1LMZA 2OFKA 4B24A 1XQPA 2NOZA 4UOBA 2OFIA 1LWVA 1PVSA 4E9FA 3S6IA 4B23A 4DK9A 1KG4A 3F10A 4AI5A 4EW0A 2NOFA 2YG8A 2NOEA 3N0UA 1ORPA 1YQRA 1YQKA 4UNFA 4OFHA 1LWYA 4B21A 3OH6A 1KQJA 3FHGA 1WEIA 1KG7A 3G0QA 1XQOA 3KNTA 1KO9A 1WEFA 1N3CA 3N5NX 3IH7A 3F0ZA 4EJYA 2JHJA 4E9EA 1KG2A 3CWUA 1YQLA 2XHIA 1ORNA 5DPKA 5AN4A 1P59A 1PU8A 4B22A 4HSBA 4EJZA 1KG6A 1LWWA 4E9HA 1NKUA 1P7MA 4OFAA 4EA5A 1VRLA 4EVVA 2JHNA 3OGDA 1MUDA 3I0WA 1MPGA 1PU7A 2I5WA 4YPRA 1M3HA 2JG6A 2ABKA 5CHZA 1EBMA 1KG5A 3CWSA 1KG3A 4E9GA 1KEAA 3CWAA 4YOQA 4EW4A 5KN9A 1XG7A 1FN7A 1N3AA 1WEGA 3CVTA 3CW7A 4EA4A 1HU0A 1MUNA 4PIIA 2H56A 1YQMA 1RRSA 4AIAA 1RRQA
chains in the Genus database with same CATH superfamily
4AI4A 4OFEA 3OS1A 4YPHA 1N39A 3FHFA 5KN8A 1DIZA 3CWTA 3IHOA 3OYMA 2YG9A 2NOHA 2NOBA 2NOLA 3OH9A 1NGNA 3KTUA 3D4VA 1PU6A 3I0XA 3VW4A 3CVSA 1M3QA 3FSPA 1MUYA 1U84A 3OYDA 2NOIA 1LMZA 2OFKA 4B24A 4BE2A 1XQPA 2NOZA 4UOBA 2OFIA 3S3MA 3OYCA 1LWVA 1PVSA 4E9FA 3S6IA 3L2WA 4B23A 4DK9A 1KG4A 2JPSA 4E7KA 5FROA 3L2QA 3F10A 3R2XC 4AI5A 3L2VA 2YG8A 4EW0A 2NOEA 2NOFA 3OYLA 4BE1A 3N0UA 1ORPA 1YQRA 1YQKA 4UNFA 4OFHA 1LWYA 4B21A 3OYNA 2W03A 3OH6A 1KQJA 3FHGA 3LCNA 1WEIA 1KG7A 3G0QA 3S3NA 3OYJA 1XQOA 3KNTA 1KO9A 3S3OA 1WEFA 1N3CA 5FRNA 4E7HA 3N5NX 3IH7A 3F0ZA 3L2RA 4ZTFA 4EJYA 2JHJA 4E9EA 1KG2A 3CWUA 1YQLA 2XHIA 3OYIA 3OYEA 5DPKA 5AN4A 1ORNA 1P59A 1PU8A 4B22A 4HSBA 4EJZA 1KG6A 4NZGA 1LWWA 3L2UA 4E9HA 1NKUA 3OYGA 3NNQA 1P7MA 4OFAA 4BACA 4EA5A 3OY9A 4BDYA 1VRLA 4EVVA 2JHNA 3OGDA 1MUDA 3I0WA 1MPGA 1PU7A 2I5WA 4YPRA 1M3HA 3OS2A 2JG6A 2ABKA 5CHZA 1EBMA 4BE0A 1KG5A 2V75A 3CWSA 1KG3A 4E9GA 1KEAA 3CWAA 4ZTJA 3OS0A 4YOQA 3OYAA 4BDZA 4E7JA 3OYHA 4EW4A 5KN9A 3OYKA 1XG7A 4E7LA 4IKFA 1FN7A 1N3AA 3OYFA 4E7IA 1WEGA 3OYBA 3CVTA 3CW7A 2W04A 4EA4A 1HU0A 1MUNA 4PIIA 2H56A 1YQMA 1RRSA 5FRMA 4AIAA 1RRQA
chains in the Genus database with same CATH topology
4AI4A 4OFEA 4YPHA 1N39A 3FHFA 5KN8A 1DIZA 3CWTA 3IHOA 2YG9A 2NOHA 2NOBA 2NOLA 3OH9A 1NGNA 3KTUA 3D4VA 1PU6A 3I0XA 3CVSA 1M3QA 3FSPA 1MUYA 2NOIA 1LMZA 2OFKA 4B24A 1XQPA 2NOZA 4UOBA 2OFIA 1LWVA 1PVSA 4E9FA 3S6IA 4B23A 4DK9A 1KG4A 3F10A 4AI5A 4EW0A 2NOFA 2YG8A 2NOEA 3N0UA 1ORPA 1YQRA 1YQKA 4UNFA 4OFHA 1LWYA 4B21A 3OH6A 1KQJA 3FHGA 1WEIA 1KG7A 3G0QA 1XQOA 3KNTA 1KO9A 1WEFA 1N3CA 3N5NX 3IH7A 3F0ZA 4EJYA 2JHJA 4E9EA 1KG2A 3CWUA 1YQLA 2XHIA 1ORNA 5DPKA 5AN4A 1P59A 1PU8A 4B22A 4HSBA 4EJZA 1KG6A 1LWWA 4E9HA 1NKUA 1P7MA 4OFAA 4EA5A 1VRLA 4EVVA 2JHNA 3OGDA 1MUDA 3I0WA 1MPGA 1PU7A 2I5WA 4YPRA 1M3HA 2JG6A 2ABKA 5CHZA 1EBMA 1KG5A 3CWSA 1KG3A 4E9GA 1KEAA 3CWAA 4YOQA 4EW4A 5KN9A 1XG7A 1FN7A 1N3AA 1WEGA 3CVTA 3CW7A 4EA4A 1HU0A 1MUNA 4PIIA 2H56A 1YQMA 1RRSA 4AIAA 1RRQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AI4 A;  4OFE A;  4YPH A;  1N39 A;  3FHF A;  5KN8 A;  1DIZ A;  3CWT A;  3IHO A;  2YG9 A;  2NOH A;  2NOB A;  2NOL A;  3OH9 A;  1NGN A;  3KTU A;  3D4V A;  1PU6 A;  3I0X A;  3CVS A;  1M3Q A;  3FSP A;  1MUY A;  2NOI A;  1LMZ A;  2OFK A;  4B24 A;  1XQP A;  2NOZ A;  4UOB A;  2OFI A;  1LWV A;  1PVS A;  4E9F A;  3S6I A;  4B23 A;  4DK9 A;  1KG4 A;  3F10 A;  4AI5 A;  4EW0 A;  2NOF A;  2YG8 A;  2NOE A;  3N0U A;  1ORP A;  1YQR A;  1YQK A;  4UNF A;  4OFH A;  1LWY A;  4B21 A;  3OH6 A;  1KQJ A;  3FHG A;  1WEI A;  1KG7 A;  3G0Q A;  1XQO A;  3KNT A;  1KO9 A;  1WEF A;  1N3C A;  3N5N X;  3IH7 A;  3F0Z A;  4EJY A;  2JHJ A;  4E9E A;  1KG2 A;  3CWU A;  1YQL A;  2XHI A;  1ORN A;  5DPK A;  5AN4 A;  1P59 A;  1PU8 A;  4B22 A;  4HSB A;  4EJZ A;  1KG6 A;  1LWW A;  4E9H A;  1NKU A;  1P7M A;  4OFA A;  4EA5 A;  1VRL A;  4EVV A;  2JHN A;  3OGD A;  1MUD A;  3I0W A;  1MPG A;  1PU7 A;  2I5W A;  4YPR A;  1M3H A;  2JG6 A;  2ABK A;  5CHZ A;  1EBM A;  1KG5 A;  3CWS A;  1KG3 A;  4E9G A;  1KEA A;  3CWA A;  4YOQ A;  4EW4 A;  5KN9 A;  1XG7 A;  1FN7 A;  1N3A A;  1WEG A;  3CVT A;  3CW7 A;  4EA4 A;  1HU0 A;  1MUN A;  4PII A;  2H56 A;  1YQM A;  1RRS A;  4AIA A;  1RRQ A; 
#chains in the Genus database with same CATH topology
 4AI4 A;  4OFE A;  3OS1 A;  4YPH A;  1N39 A;  3FHF A;  5KN8 A;  1DIZ A;  3CWT A;  3IHO A;  3OYM A;  2YG9 A;  2NOH A;  2NOB A;  2NOL A;  3OH9 A;  1NGN A;  3KTU A;  3D4V A;  1PU6 A;  3I0X A;  3VW4 A;  3CVS A;  1M3Q A;  3FSP A;  1MUY A;  1U84 A;  3OYD A;  2NOI A;  1LMZ A;  2OFK A;  4B24 A;  4BE2 A;  1XQP A;  2NOZ A;  4UOB A;  2OFI A;  3S3M A;  3OYC A;  1LWV A;  1PVS A;  4E9F A;  3S6I A;  3L2W A;  4B23 A;  4DK9 A;  1KG4 A;  2JPS A;  4E7K A;  5FRO A;  3L2Q A;  3F10 A;  3R2X C;  4AI5 A;  3L2V A;  2YG8 A;  4EW0 A;  2NOE A;  2NOF A;  3OYL A;  4BE1 A;  3N0U A;  1ORP A;  1YQR A;  1YQK A;  4UNF A;  4OFH A;  1LWY A;  4B21 A;  3OYN A;  2W03 A;  3OH6 A;  1KQJ A;  3FHG A;  3LCN A;  1WEI A;  1KG7 A;  3G0Q A;  3S3N A;  3OYJ A;  1XQO A;  3KNT A;  1KO9 A;  3S3O A;  1WEF A;  1N3C A;  5FRN A;  4E7H A;  3N5N X;  3IH7 A;  3F0Z A;  3L2R A;  4ZTF A;  4EJY A;  2JHJ A;  4E9E A;  1KG2 A;  3CWU A;  1YQL A;  2XHI A;  3OYI A;  3OYE A;  5DPK A;  5AN4 A;  1ORN A;  1P59 A;  1PU8 A;  4B22 A;  4HSB A;  4EJZ A;  1KG6 A;  4NZG A;  1LWW A;  3L2U A;  4E9H A;  1NKU A;  3OYG A;  3NNQ A;  1P7M A;  4OFA A;  4BAC A;  4EA5 A;  3OY9 A;  4BDY A;  1VRL A;  4EVV A;  2JHN A;  3OGD A;  1MUD A;  3I0W A;  1MPG A;  1PU7 A;  2I5W A;  4YPR A;  1M3H A;  3OS2 A;  2JG6 A;  2ABK A;  5CHZ A;  1EBM A;  4BE0 A;  1KG5 A;  2V75 A;  3CWS A;  1KG3 A;  4E9G A;  1KEA A;  3CWA A;  4ZTJ A;  3OS0 A;  4YOQ A;  3OYA A;  4BDZ A;  4E7J A;  3OYH A;  4EW4 A;  5KN9 A;  3OYK A;  1XG7 A;  4E7L A;  4IKF A;  1FN7 A;  1N3A A;  3OYF A;  4E7I A;  1WEG A;  3OYB A;  3CVT A;  3CW7 A;  2W04 A;  4EA4 A;  1HU0 A;  1MUN A;  4PII A;  2H56 A;  1YQM A;  1RRS A;  5FRM A;  4AIA A;  1RRQ A; 
#chains in the Genus database with same CATH homology
 4AI4 A;  4OFE A;  4YPH A;  1N39 A;  3FHF A;  5KN8 A;  1DIZ A;  3CWT A;  3IHO A;  2YG9 A;  2NOH A;  2NOB A;  2NOL A;  3OH9 A;  1NGN A;  3KTU A;  3D4V A;  1PU6 A;  3I0X A;  3CVS A;  1M3Q A;  3FSP A;  1MUY A;  2NOI A;  1LMZ A;  2OFK A;  4B24 A;  1XQP A;  2NOZ A;  4UOB A;  2OFI A;  1LWV A;  1PVS A;  4E9F A;  3S6I A;  4B23 A;  4DK9 A;  1KG4 A;  3F10 A;  4AI5 A;  4EW0 A;  2NOF A;  2YG8 A;  2NOE A;  3N0U A;  1ORP A;  1YQR A;  1YQK A;  4UNF A;  4OFH A;  1LWY A;  4B21 A;  3OH6 A;  1KQJ A;  3FHG A;  1WEI A;  1KG7 A;  3G0Q A;  1XQO A;  3KNT A;  1KO9 A;  1WEF A;  1N3C A;  3N5N X;  3IH7 A;  3F0Z A;  4EJY A;  2JHJ A;  4E9E A;  1KG2 A;  3CWU A;  1YQL A;  2XHI A;  1ORN A;  5DPK A;  5AN4 A;  1P59 A;  1PU8 A;  4B22 A;  4HSB A;  4EJZ A;  1KG6 A;  1LWW A;  4E9H A;  1NKU A;  1P7M A;  4OFA A;  4EA5 A;  1VRL A;  4EVV A;  2JHN A;  3OGD A;  1MUD A;  3I0W A;  1MPG A;  1PU7 A;  2I5W A;  4YPR A;  1M3H A;  2JG6 A;  2ABK A;  5CHZ A;  1EBM A;  1KG5 A;  3CWS A;  1KG3 A;  4E9G A;  1KEA A;  3CWA A;  4YOQ A;  4EW4 A;  5KN9 A;  1XG7 A;  1FN7 A;  1N3A A;  1WEG A;  3CVT A;  3CW7 A;  4EA4 A;  1HU0 A;  1MUN A;  4PII A;  2H56 A;  1YQM A;  1RRS A;  4AIA A;  1RRQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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