1WK9A

Structural basis for non-cognate amino acid discrimination by the valyl-trna synthetase editing domain
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
143
structure length
143
Chain Sequence
GKLYTLRYEVEGGGFIEIATVRPETVFADQAIAVHPEDERYRHLLGKRARIPLTEVWIPILADPAVEKDFGTGALKVTPAHDPLDYEIGERHGLKPVSVINLEGRMEGERVPEALRGLDRFEARRKAVELFREAGHLVKEEDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Non-cognate Amino Acid Discrimination by the Valyl-tRNA Synthetase Editing Domain
pubmed doi rcsb
molecule tags Ligase
source organism Thermus thermophilus
molecule keywords Valyl-tRNA synthetase
total genus 39
structure length 143
sequence length 143
ec nomenclature ec 6.1.1.9: Valine--tRNA ligase.
pdb deposition date 2004-05-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.740.10 Alpha Beta Alpha-Beta Complex Isoleucyl-tRNA Synthetase; domain 2 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 1wk9A00
4AS1A 3PZ6A 3ZJTA 3ZGZA 1JZSA 2WFDA 1ILEA 5AGHA 3PZ5A 1FFYA 5AGSA 3PZ0A 5AGTA 2AJIA 1UDZA 2AJGA 1WKAA 5AGRA 1H3NA 5AGJA 2WFGA 1WK8A 3O0AA 1QU3A 4CQNA 1QU2A 4ARCA 1IVSA 4K48A 1WNYA 2BYTA 1OBHA 1WZ2A 2BTEA 2AJHA 1WK9A 3ZJUA 1WNZA 5AGIA 4K47A 2WFEA 2V0GA 3ZJVA 1WKBA 1JZQA 4ARIA 1GAXA 4AQ7A 1OBCA 2V0CA 1UE0A
chains in the Genus database with same CATH superfamily
4AS1A 3PZ6A 3ZJTA 3ZGZA 1JZSA 2WFDA 1ILEA 5AGHA 3PZ5A 1FFYA 5AGSA 3PZ0A 5AGTA 2AJIA 1UDZA 2AJGA 1WKAA 5AGRA 1H3NA 5AGJA 2WFGA 1WK8A 3O0AA 1QU3A 4CQNA 1QU2A 4ARCA 1IVSA 4K48A 1WNYA 2BYTA 1OBHA 1WZ2A 2BTEA 2AJHA 1WK9A 3ZJUA 1WNZA 5AGIA 4K47A 2WFEA 2V0GA 3ZJVA 1WKBA 1JZQA 4ARIA 1GAXA 4AQ7A 1OBCA 2V0CA 1UE0A
chains in the Genus database with same CATH topology
4AS1A 3PZ6A 3ZJTA 3ZGZA 1JZSA 2WFDA 1ILEA 5AGHA 3PZ5A 1FFYA 5AGSA 3PZ0A 5AGTA 2AJIA 1UDZA 2AJGA 1WKAA 5AGRA 1H3NA 5AGJA 2WFGA 1WK8A 3O0AA 1QU3A 4CQNA 1QU2A 4ARCA 1IVSA 4K48A 1WNYA 2BYTA 1OBHA 1WZ2A 2BTEA 2AJHA 1WK9A 3ZJUA 1WNZA 5AGIA 4K47A 2WFEA 2V0GA 3ZJVA 1WKBA 1JZQA 4ARIA 1GAXA 4AQ7A 1OBCA 2V0CA 1UE0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AS1 A;  3PZ6 A;  3ZJT A;  3ZGZ A;  1JZS A;  2WFD A;  1ILE A;  5AGH A;  3PZ5 A;  1FFY A;  5AGS A;  3PZ0 A;  5AGT A;  2AJI A;  1UDZ A;  2AJG A;  1WKA A;  5AGR A;  1H3N A;  5AGJ A;  2WFG A;  1WK8 A;  3O0A A;  1QU3 A;  4CQN A;  1QU2 A;  4ARC A;  1IVS A;  4K48 A;  1WNY A;  2BYT A;  1OBH A;  1WZ2 A;  2BTE A;  2AJH A;  1WK9 A;  3ZJU A;  1WNZ A;  5AGI A;  4K47 A;  2WFE A;  2V0G A;  3ZJV A;  1WKB A;  1JZQ A;  4ARI A;  1GAX A;  4AQ7 A;  1OBC A;  2V0C A;  1UE0 A; 
#chains in the Genus database with same CATH topology
 4AS1 A;  3PZ6 A;  3ZJT A;  3ZGZ A;  1JZS A;  2WFD A;  1ILE A;  5AGH A;  3PZ5 A;  1FFY A;  5AGS A;  3PZ0 A;  5AGT A;  2AJI A;  1UDZ A;  2AJG A;  1WKA A;  5AGR A;  1H3N A;  5AGJ A;  2WFG A;  1WK8 A;  3O0A A;  1QU3 A;  4CQN A;  1QU2 A;  4ARC A;  1IVS A;  4K48 A;  1WNY A;  2BYT A;  1OBH A;  1WZ2 A;  2BTE A;  2AJH A;  1WK9 A;  3ZJU A;  1WNZ A;  5AGI A;  4K47 A;  2WFE A;  2V0G A;  3ZJV A;  1WKB A;  1JZQ A;  4ARI A;  1GAX A;  4AQ7 A;  1OBC A;  2V0C A;  1UE0 A; 
#chains in the Genus database with same CATH homology
 4AS1 A;  3PZ6 A;  3ZJT A;  3ZGZ A;  1JZS A;  2WFD A;  1ILE A;  5AGH A;  3PZ5 A;  1FFY A;  5AGS A;  3PZ0 A;  5AGT A;  2AJI A;  1UDZ A;  2AJG A;  1WKA A;  5AGR A;  1H3N A;  5AGJ A;  2WFG A;  1WK8 A;  3O0A A;  1QU3 A;  4CQN A;  1QU2 A;  4ARC A;  1IVS A;  4K48 A;  1WNY A;  2BYT A;  1OBH A;  1WZ2 A;  2BTE A;  2AJH A;  1WK9 A;  3ZJU A;  1WNZ A;  5AGI A;  4K47 A;  2WFE A;  2V0G A;  3ZJV A;  1WKB A;  1JZQ A;  4ARI A;  1GAX A;  4AQ7 A;  1OBC A;  2V0C A;  1UE0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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