1WK9A

Structural basis for non-cognate amino acid discrimination by the valyl-trna synthetase editing domain
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
143
structure length
143
Chain Sequence
GKLYTLRYEVEGGGFIEIATVRPETVFADQAIAVHPEDERYRHLLGKRARIPLTEVWIPILADPAVEKDFGTGALKVTPAHDPLDYEIGERHGLKPVSVINLEGRMEGERVPEALRGLDRFEARRKAVELFREAGHLVKEEDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Non-cognate Amino Acid Discrimination by the Valyl-tRNA Synthetase Editing Domain
pubmed doi rcsb
source organism Thermus thermophilus
molecule tags Ligase
molecule keywords Valyl-tRNA synthetase
total genus 39
structure length 143
sequence length 143
ec nomenclature ec 6.1.1.9: Valine--tRNA ligase.
pdb deposition date 2004-05-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.740.10 Alpha Beta Alpha-Beta Complex Isoleucyl-tRNA Synthetase; domain 2 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 1wk9A00
1QU3A 4AQ7A 2AJHA 4K47A 4CQNA 1WK9A 2AJIA 2WFEA 2BYTA 5AGTA 1OBCA 1WNZA 1WK8A 1WZ2A 2V0CA 1UE0A 1JZQA 2WFGA 1H3NA 3ZJVA 1FFYA 3PZ6A 2WFDA 1GAXA 1WKBA 3ZJTA 2V0GA 5AGIA 2BTEA 1JZSA 3PZ0A 5AGRA 1OBHA 4ARIA 5AGSA 1ILEA 5AGHA 3O0AA 1IVSA 5AGJA 2AJGA 1WKAA 4AS1A 4ARCA 1QU2A 3PZ5A 3ZGZA 1WNYA 4K48A 1UDZA 3ZJUA
chains in the Genus database with same CATH superfamily
1QU3A 4AQ7A 2AJHA 4K47A 4CQNA 1WK9A 2AJIA 2WFEA 2BYTA 5AGTA 1OBCA 1WNZA 1WK8A 1WZ2A 2V0CA 1UE0A 1JZQA 2WFGA 1H3NA 3ZJVA 1FFYA 3PZ6A 2WFDA 1GAXA 1WKBA 3ZJTA 2V0GA 5AGIA 2BTEA 1JZSA 3PZ0A 5AGRA 1OBHA 4ARIA 5AGSA 1ILEA 5AGHA 3O0AA 1IVSA 5AGJA 2AJGA 1WKAA 4AS1A 4ARCA 1QU2A 3PZ5A 3ZGZA 1WNYA 4K48A 1UDZA 3ZJUA
chains in the Genus database with same CATH topology
1QU3A 4AQ7A 2AJHA 4K47A 4CQNA 1WK9A 2AJIA 2WFEA 2BYTA 5AGTA 1OBCA 1WNZA 1WK8A 1WZ2A 2V0CA 1UE0A 1JZQA 2WFGA 1H3NA 3ZJVA 1FFYA 3PZ6A 2WFDA 1GAXA 1WKBA 3ZJTA 2V0GA 5AGIA 2BTEA 1JZSA 3PZ0A 5AGRA 1OBHA 4ARIA 5AGSA 1ILEA 5AGHA 3O0AA 1IVSA 5AGJA 2AJGA 1WKAA 4AS1A 4ARCA 1QU2A 3PZ5A 3ZGZA 1WNYA 4K48A 1UDZA 3ZJUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QU3 A;  4AQ7 A;  2AJH A;  4K47 A;  4CQN A;  1WK9 A;  2AJI A;  2WFE A;  2BYT A;  5AGT A;  1OBC A;  1WNZ A;  1WK8 A;  1WZ2 A;  2V0C A;  1UE0 A;  1JZQ A;  2WFG A;  1H3N A;  3ZJV A;  1FFY A;  3PZ6 A;  2WFD A;  1GAX A;  1WKB A;  3ZJT A;  2V0G A;  5AGI A;  2BTE A;  1JZS A;  3PZ0 A;  5AGR A;  1OBH A;  4ARI A;  5AGS A;  1ILE A;  5AGH A;  3O0A A;  1IVS A;  5AGJ A;  2AJG A;  1WKA A;  4AS1 A;  4ARC A;  1QU2 A;  3PZ5 A;  3ZGZ A;  1WNY A;  4K48 A;  1UDZ A;  3ZJU A; 
#chains in the Genus database with same CATH topology
 1QU3 A;  4AQ7 A;  2AJH A;  4K47 A;  4CQN A;  1WK9 A;  2AJI A;  2WFE A;  2BYT A;  5AGT A;  1OBC A;  1WNZ A;  1WK8 A;  1WZ2 A;  2V0C A;  1UE0 A;  1JZQ A;  2WFG A;  1H3N A;  3ZJV A;  1FFY A;  3PZ6 A;  2WFD A;  1GAX A;  1WKB A;  3ZJT A;  2V0G A;  5AGI A;  2BTE A;  1JZS A;  3PZ0 A;  5AGR A;  1OBH A;  4ARI A;  5AGS A;  1ILE A;  5AGH A;  3O0A A;  1IVS A;  5AGJ A;  2AJG A;  1WKA A;  4AS1 A;  4ARC A;  1QU2 A;  3PZ5 A;  3ZGZ A;  1WNY A;  4K48 A;  1UDZ A;  3ZJU A; 
#chains in the Genus database with same CATH homology
 1QU3 A;  4AQ7 A;  2AJH A;  4K47 A;  4CQN A;  1WK9 A;  2AJI A;  2WFE A;  2BYT A;  5AGT A;  1OBC A;  1WNZ A;  1WK8 A;  1WZ2 A;  2V0C A;  1UE0 A;  1JZQ A;  2WFG A;  1H3N A;  3ZJV A;  1FFY A;  3PZ6 A;  2WFD A;  1GAX A;  1WKB A;  3ZJT A;  2V0G A;  5AGI A;  2BTE A;  1JZS A;  3PZ0 A;  5AGR A;  1OBH A;  4ARI A;  5AGS A;  1ILE A;  5AGH A;  3O0A A;  1IVS A;  5AGJ A;  2AJG A;  1WKA A;  4AS1 A;  4ARC A;  1QU2 A;  3PZ5 A;  3ZGZ A;  1WNY A;  4K48 A;  1UDZ A;  3ZJU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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