1WL6A

Mg-substituted form of e. coli aminopeptidase p
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
sequence length
440
structure length
440
Chain Sequence
SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional implications of metal ion selection in aminopeptidase p, a metalloprotease with a dinuclear metal center
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Xaa-Pro aminopeptidase
total genus 156
structure length 440
sequence length 440
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2004-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF05195 AMP_N Aminopeptidase P, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1wl6A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1wl6A02
2MATA 2BWXA 1M35A 3PKDA 2BWYA 3L24A 2P98A 4HXXA 5E5BA 2DFIA 1N51A 2GU4A 2V3YA 2BB7A 1XNZA 5CLSA 1BN5A 4Z7MA 4FKCA 1W2MA 4U6EA 1B6AA 1WKMA 2EVCA 2Q96A 1YJ3A 4FLIA 2BHBA 2B3LA 2GTXA 3QOCA 1JAWA 2GU5A 3CB5A 2GG8A 3PKEA 4ZWPA 2NQ6A 4KM3A 2OAZA 3BIPA 4U75A 5CNXA 1XGSA 2BWTA 1KQ0A 1WL6A 4ZWUA 2Q93A 1C24A 4U6CA 4U71A 4IKSA 2GG3A 4PNCA 1QXWA 4FLLA 3IG4A 4FLJA 4B28A 3PKBA 2V3XA 4FO8A 2GG9A 3CTZA 2IW2A 3PKCA 5FCFA 4S2TP 2EA4A 3IU8A 3TB5A 4RZZA 2V6CA 2Q92A 3MR1A 2ZSGA 2EA2A 2G6PA 3PN9A 4JUQA 4RZYA 1B59A 3RORA 3IU9A 2GZ5A 2BHDA 2BN7A 5D6EA 1BOAA 4RGZ1 3FMQA 4U69A 2BHCA 3IU7A 1WY2A 1QXYA 4U70A 3CB6A 1W7VA 1MATA 2EVMA 1R5HA 5JI6A 4IKTA 2GGCA 4OOKA 2Q8KA 2P9AA 1PV9A 3OOOA 4U6WA 2GU7A 5CE6A 1A16A 1WBQA 1KP0A 4S00A 4FLKA 4FUKA 4EGEA 4FO7A 4ZNGA 1XGNA 1C21A 2BWSA 2BWVA 3OVKA 1R58A 2OKNA 5E2CA 2V3ZA 2Q95A 2HOWA 4IDYA 1WN1A 4IECA 4PV4A 4A6VA 1C27A 3Q6DA 3FM3A 4IU6A 3PEBA 2ADUA 2GG2A 2P99A 5JFRA 5JHUA 3BITA 2BHAA 4IPAA 2GA2A 1YW7A 2GG7A 5FCHA 1C22A 3MATA 2NQ7A 4A6WA 3D27A 2GU6A 4U73A 2GGBA 2BH3A 4IKUA 3IL0A 2BWWA 3S6BA 4U6ZA 4U1BA 4IKRA 2GG5A 3RVAA 1O0XA 5CIKA 1R5GA 3TAVA 4R60A 2B3KA 2GG0A 4MATA 1QXZA 1XGOA 4S2RP 1WLRA 1WL9A 4S01A 2BWUA 2B3HA 3PKAA 1XGMA 3MX6A 1YW8A 2EVOA 1YVMA 4U6JA 5CDLA 1C23A 4U76A 5D6FA 3L7GA 1QZYA 3I7MA 1CHMA 3O5VA 3FMRA 4IF7A 1KQ9A 3BIQA 5CDEA 5CDVA 1Y1NA 2Q94A 4QR8A 1YW9A 4ZWOA
chains in the Genus database with same CATH superfamily
2MATA 2BWXA 1M35A 3PKDA 2BWYA 3L24A 2P98A 4HXXA 5E5BA 2DFIA 1N51A 2GU4A 2V3YA 2BB7A 1XNZA 5CLSA 1BN5A 4Z7MA 4FKCA 1W2MA 4U6EA 1B6AA 1WKMA 2EVCA 2Q96A 1YJ3A 4FLIA 2BHBA 2B3LA 2GTXA 3QOCA 1JAWA 2GU5A 3CB5A 2GG8A 3PKEA 4ZWPA 2NQ6A 4KM3A 2OAZA 3BIPA 4U75A 5CNXA 1XGSA 2BWTA 1KQ0A 1WL6A 4ZWUA 2Q93A 1C24A 4U6CA 4U71A 4IKSA 2GG3A 4PNCA 1QXWA 4FLLA 3IG4A 4FLJA 4B28A 3PKBA 2V3XA 4FO8A 2GG9A 3CTZA 2IW2A 3PKCA 5FCFA 4S2TP 2EA4A 3IU8A 3TB5A 4RZZA 2V6CA 2Q92A 3MR1A 2ZSGA 2EA2A 2G6PA 3PN9A 4JUQA 4RZYA 1B59A 3RORA 3IU9A 2GZ5A 2BHDA 2BN7A 5D6EA 1BOAA 4RGZ1 3FMQA 4U69A 2BHCA 3IU7A 1WY2A 1QXYA 4U70A 3CB6A 1W7VA 1MATA 2EVMA 1R5HA 5JI6A 4IKTA 2GGCA 4OOKA 2Q8KA 2P9AA 1PV9A 3OOOA 4U6WA 2GU7A 5CE6A 1A16A 1WBQA 1KP0A 4S00A 4FLKA 4FUKA 4EGEA 4FO7A 4ZNGA 1XGNA 1C21A 2BWSA 2BWVA 3OVKA 1R58A 2OKNA 5E2CA 2V3ZA 2Q95A 2HOWA 4IDYA 1WN1A 4IECA 4PV4A 4A6VA 1C27A 3Q6DA 3FM3A 4IU6A 3PEBA 2ADUA 2GG2A 2P99A 5JFRA 5JHUA 3BITA 2BHAA 4IPAA 2GA2A 1YW7A 2GG7A 5FCHA 1C22A 3MATA 2NQ7A 4A6WA 3D27A 2GU6A 4U73A 2GGBA 2BH3A 4IKUA 3IL0A 2BWWA 3S6BA 4U6ZA 4U1BA 4IKRA 2GG5A 3RVAA 1O0XA 5CIKA 1R5GA 3TAVA 4R60A 2B3KA 2GG0A 4MATA 1QXZA 1XGOA 4S2RP 1WLRA 1WL9A 4S01A 2BWUA 2B3HA 3PKAA 1XGMA 3MX6A 1YW8A 2EVOA 1YVMA 4U6JA 5CDLA 1C23A 4U76A 5D6FA 3L7GA 1QZYA 3I7MA 1CHMA 3O5VA 3FMRA 4IF7A 1KQ9A 3BIQA 5CDEA 5CDVA 1Y1NA 2Q94A 4QR8A 1YW9A 4ZWOA
chains in the Genus database with same CATH topology
2MATA 2BWXA 1M35A 3PKDA 2BWYA 3L24A 2P98A 4HXXA 5E5BA 2DFIA 1N51A 2GU4A 2V3YA 2BB7A 1XNZA 5CLSA 1BN5A 4Z7MA 4FKCA 1W2MA 4U6EA 1B6AA 1WKMA 2EVCA 2Q96A 1YJ3A 4FLIA 2BHBA 2B3LA 2GTXA 3QOCA 1JAWA 2GU5A 3CB5A 2GG8A 3PKEA 4ZWPA 2NQ6A 4KM3A 2OAZA 3BIPA 4U75A 5CNXA 1XGSA 2BWTA 1KQ0A 1WL6A 4ZWUA 2Q93A 1C24A 4U6CA 4U71A 4IKSA 2GG3A 4PNCA 1QXWA 4FLLA 3IG4A 4FLJA 4B28A 3PKBA 2V3XA 4FO8A 2GG9A 3CTZA 2IW2A 3PKCA 5FCFA 4S2TP 2EA4A 3IU8A 3TB5A 4RZZA 2V6CA 2Q92A 3MR1A 2ZSGA 2EA2A 2G6PA 3PN9A 4JUQA 4RZYA 1B59A 3RORA 3IU9A 2GZ5A 2BHDA 2BN7A 5D6EA 1BOAA 4RGZ1 3FMQA 4U69A 2BHCA 3IU7A 1WY2A 1QXYA 4U70A 3CB6A 1W7VA 1MATA 2EVMA 1R5HA 5JI6A 4IKTA 2GGCA 4OOKA 2Q8KA 2P9AA 1PV9A 3OOOA 4U6WA 2GU7A 5CE6A 1A16A 1WBQA 1KP0A 4S00A 4FLKA 4FUKA 4EGEA 4FO7A 4ZNGA 1XGNA 1C21A 2BWSA 2BWVA 3OVKA 1R58A 2OKNA 5E2CA 2V3ZA 2Q95A 2HOWA 4IDYA 1WN1A 4IECA 4PV4A 4A6VA 1C27A 3Q6DA 3FM3A 4IU6A 3PEBA 2ADUA 2GG2A 2P99A 5JFRA 5JHUA 3BITA 2BHAA 4IPAA 2GA2A 1YW7A 2GG7A 5FCHA 1C22A 3MATA 2NQ7A 4A6WA 3D27A 2GU6A 4U73A 2GGBA 2BH3A 4IKUA 3IL0A 2BWWA 3S6BA 4U6ZA 4U1BA 4IKRA 2GG5A 3RVAA 1O0XA 5CIKA 1R5GA 3TAVA 4R60A 2B3KA 2GG0A 4MATA 1QXZA 1XGOA 4S2RP 1WLRA 1WL9A 4S01A 2BWUA 2B3HA 3PKAA 1XGMA 3MX6A 1YW8A 2EVOA 1YVMA 4U6JA 5CDLA 1C23A 4U76A 5D6FA 3L7GA 1QZYA 3I7MA 1CHMA 3O5VA 3FMRA 4IF7A 1KQ9A 3BIQA 5CDEA 5CDVA 1Y1NA 2Q94A 4QR8A 1YW9A 4ZWOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MAT A;  2BWX A;  1M35 A;  3PKD A;  2BWY A;  3L24 A;  2P98 A;  4HXX A;  5E5B A;  2DFI A;  1N51 A;  2GU4 A;  2V3Y A;  2BB7 A;  1XNZ A;  5CLS A;  1BN5 A;  4Z7M A;  4FKC A;  1W2M A;  4U6E A;  1B6A A;  1WKM A;  2EVC A;  2Q96 A;  1YJ3 A;  4FLI A;  2BHB A;  2B3L A;  2GTX A;  3QOC A;  1JAW A;  2GU5 A;  3CB5 A;  2GG8 A;  3PKE A;  4ZWP A;  2NQ6 A;  4KM3 A;  2OAZ A;  3BIP A;  4U75 A;  5CNX A;  1XGS A;  2BWT A;  1KQ0 A;  1WL6 A;  4ZWU A;  2Q93 A;  1C24 A;  4U6C A;  4U71 A;  4IKS A;  2GG3 A;  4PNC A;  1QXW A;  4FLL A;  3IG4 A;  4FLJ A;  4B28 A;  3PKB A;  2V3X A;  4FO8 A;  2GG9 A;  3CTZ A;  2IW2 A;  3PKC A;  5FCF A;  4S2T P;  2EA4 A;  3IU8 A;  3TB5 A;  4RZZ A;  2V6C A;  2Q92 A;  3MR1 A;  2ZSG A;  2EA2 A;  2G6P A;  3PN9 A;  4JUQ A;  4RZY A;  1B59 A;  3ROR A;  3IU9 A;  2GZ5 A;  2BHD A;  2BN7 A;  5D6E A;  1BOA A;  4RGZ 1;  3FMQ A;  4U69 A;  2BHC A;  3IU7 A;  1WY2 A;  1QXY A;  4U70 A;  3CB6 A;  1W7V A;  1MAT A;  2EVM A;  1R5H A;  5JI6 A;  4IKT A;  2GGC A;  4OOK A;  2Q8K A;  2P9A A;  1PV9 A;  3OOO A;  4U6W A;  2GU7 A;  5CE6 A;  1A16 A;  1WBQ A;  1KP0 A;  4S00 A;  4FLK A;  4FUK A;  4EGE A;  4FO7 A;  4ZNG A;  1XGN A;  1C21 A;  2BWS A;  2BWV A;  3OVK A;  1R58 A;  2OKN A;  5E2C A;  2V3Z A;  2Q95 A;  2HOW A;  4IDY A;  1WN1 A;  4IEC A;  4PV4 A;  4A6V A;  1C27 A;  3Q6D A;  3FM3 A;  4IU6 A;  3PEB A;  2ADU A;  2GG2 A;  2P99 A;  5JFR A;  5JHU A;  3BIT A;  2BHA A;  4IPA A;  2GA2 A;  1YW7 A;  2GG7 A;  5FCH A;  1C22 A;  3MAT A;  2NQ7 A;  4A6W A;  3D27 A;  2GU6 A;  4U73 A;  2GGB A;  2BH3 A;  4IKU A;  3IL0 A;  2BWW A;  3S6B A;  4U6Z A;  4U1B A;  4IKR A;  2GG5 A;  3RVA A;  1O0X A;  5CIK A;  1R5G A;  3TAV A;  4R60 A;  2B3K A;  2GG0 A;  4MAT A;  1QXZ A;  1XGO A;  4S2R P;  1WLR A;  1WL9 A;  4S01 A;  2BWU A;  2B3H A;  3PKA A;  1XGM A;  3MX6 A;  1YW8 A;  2EVO A;  1YVM A;  4U6J A;  5CDL A;  1C23 A;  4U76 A;  5D6F A;  3L7G A;  1QZY A;  3I7M A;  1CHM A;  3O5V A;  3FMR A;  4IF7 A;  1KQ9 A;  3BIQ A;  5CDE A;  5CDV A;  1Y1N A;  2Q94 A;  4QR8 A;  1YW9 A;  4ZWO A; 
#chains in the Genus database with same CATH topology
 2MAT A;  2BWX A;  1M35 A;  3PKD A;  2BWY A;  3L24 A;  2P98 A;  4HXX A;  5E5B A;  2DFI A;  1N51 A;  2GU4 A;  2V3Y A;  2BB7 A;  1XNZ A;  5CLS A;  1BN5 A;  4Z7M A;  4FKC A;  1W2M A;  4U6E A;  1B6A A;  1WKM A;  2EVC A;  2Q96 A;  1YJ3 A;  4FLI A;  2BHB A;  2B3L A;  2GTX A;  3QOC A;  1JAW A;  2GU5 A;  3CB5 A;  2GG8 A;  3PKE A;  4ZWP A;  2NQ6 A;  4KM3 A;  2OAZ A;  3BIP A;  4U75 A;  5CNX A;  1XGS A;  2BWT A;  1KQ0 A;  1WL6 A;  4ZWU A;  2Q93 A;  1C24 A;  4U6C A;  4U71 A;  4IKS A;  2GG3 A;  4PNC A;  1QXW A;  4FLL A;  3IG4 A;  4FLJ A;  4B28 A;  3PKB A;  2V3X A;  4FO8 A;  2GG9 A;  3CTZ A;  2IW2 A;  3PKC A;  5FCF A;  4S2T P;  2EA4 A;  3IU8 A;  3TB5 A;  4RZZ A;  2V6C A;  2Q92 A;  3MR1 A;  2ZSG A;  2EA2 A;  2G6P A;  3PN9 A;  4JUQ A;  4RZY A;  1B59 A;  3ROR A;  3IU9 A;  2GZ5 A;  2BHD A;  2BN7 A;  5D6E A;  1BOA A;  4RGZ 1;  3FMQ A;  4U69 A;  2BHC A;  3IU7 A;  1WY2 A;  1QXY A;  4U70 A;  3CB6 A;  1W7V A;  1MAT A;  2EVM A;  1R5H A;  5JI6 A;  4IKT A;  2GGC A;  4OOK A;  2Q8K A;  2P9A A;  1PV9 A;  3OOO A;  4U6W A;  2GU7 A;  5CE6 A;  1A16 A;  1WBQ A;  1KP0 A;  4S00 A;  4FLK A;  4FUK A;  4EGE A;  4FO7 A;  4ZNG A;  1XGN A;  1C21 A;  2BWS A;  2BWV A;  3OVK A;  1R58 A;  2OKN A;  5E2C A;  2V3Z A;  2Q95 A;  2HOW A;  4IDY A;  1WN1 A;  4IEC A;  4PV4 A;  4A6V A;  1C27 A;  3Q6D A;  3FM3 A;  4IU6 A;  3PEB A;  2ADU A;  2GG2 A;  2P99 A;  5JFR A;  5JHU A;  3BIT A;  2BHA A;  4IPA A;  2GA2 A;  1YW7 A;  2GG7 A;  5FCH A;  1C22 A;  3MAT A;  2NQ7 A;  4A6W A;  3D27 A;  2GU6 A;  4U73 A;  2GGB A;  2BH3 A;  4IKU A;  3IL0 A;  2BWW A;  3S6B A;  4U6Z A;  4U1B A;  4IKR A;  2GG5 A;  3RVA A;  1O0X A;  5CIK A;  1R5G A;  3TAV A;  4R60 A;  2B3K A;  2GG0 A;  4MAT A;  1QXZ A;  1XGO A;  4S2R P;  1WLR A;  1WL9 A;  4S01 A;  2BWU A;  2B3H A;  3PKA A;  1XGM A;  3MX6 A;  1YW8 A;  2EVO A;  1YVM A;  4U6J A;  5CDL A;  1C23 A;  4U76 A;  5D6F A;  3L7G A;  1QZY A;  3I7M A;  1CHM A;  3O5V A;  3FMR A;  4IF7 A;  1KQ9 A;  3BIQ A;  5CDE A;  5CDV A;  1Y1N A;  2Q94 A;  4QR8 A;  1YW9 A;  4ZWO A; 
#chains in the Genus database with same CATH homology
 2MAT A;  2BWX A;  1M35 A;  3PKD A;  2BWY A;  3L24 A;  2P98 A;  4HXX A;  5E5B A;  2DFI A;  1N51 A;  2GU4 A;  2V3Y A;  2BB7 A;  1XNZ A;  5CLS A;  1BN5 A;  4Z7M A;  4FKC A;  1W2M A;  4U6E A;  1B6A A;  1WKM A;  2EVC A;  2Q96 A;  1YJ3 A;  4FLI A;  2BHB A;  2B3L A;  2GTX A;  3QOC A;  1JAW A;  2GU5 A;  3CB5 A;  2GG8 A;  3PKE A;  4ZWP A;  2NQ6 A;  4KM3 A;  2OAZ A;  3BIP A;  4U75 A;  5CNX A;  1XGS A;  2BWT A;  1KQ0 A;  1WL6 A;  4ZWU A;  2Q93 A;  1C24 A;  4U6C A;  4U71 A;  4IKS A;  2GG3 A;  4PNC A;  1QXW A;  4FLL A;  3IG4 A;  4FLJ A;  4B28 A;  3PKB A;  2V3X A;  4FO8 A;  2GG9 A;  3CTZ A;  2IW2 A;  3PKC A;  5FCF A;  4S2T P;  2EA4 A;  3IU8 A;  3TB5 A;  4RZZ A;  2V6C A;  2Q92 A;  3MR1 A;  2ZSG A;  2EA2 A;  2G6P A;  3PN9 A;  4JUQ A;  4RZY A;  1B59 A;  3ROR A;  3IU9 A;  2GZ5 A;  2BHD A;  2BN7 A;  5D6E A;  1BOA A;  4RGZ 1;  3FMQ A;  4U69 A;  2BHC A;  3IU7 A;  1WY2 A;  1QXY A;  4U70 A;  3CB6 A;  1W7V A;  1MAT A;  2EVM A;  1R5H A;  5JI6 A;  4IKT A;  2GGC A;  4OOK A;  2Q8K A;  2P9A A;  1PV9 A;  3OOO A;  4U6W A;  2GU7 A;  5CE6 A;  1A16 A;  1WBQ A;  1KP0 A;  4S00 A;  4FLK A;  4FUK A;  4EGE A;  4FO7 A;  4ZNG A;  1XGN A;  1C21 A;  2BWS A;  2BWV A;  3OVK A;  1R58 A;  2OKN A;  5E2C A;  2V3Z A;  2Q95 A;  2HOW A;  4IDY A;  1WN1 A;  4IEC A;  4PV4 A;  4A6V A;  1C27 A;  3Q6D A;  3FM3 A;  4IU6 A;  3PEB A;  2ADU A;  2GG2 A;  2P99 A;  5JFR A;  5JHU A;  3BIT A;  2BHA A;  4IPA A;  2GA2 A;  1YW7 A;  2GG7 A;  5FCH A;  1C22 A;  3MAT A;  2NQ7 A;  4A6W A;  3D27 A;  2GU6 A;  4U73 A;  2GGB A;  2BH3 A;  4IKU A;  3IL0 A;  2BWW A;  3S6B A;  4U6Z A;  4U1B A;  4IKR A;  2GG5 A;  3RVA A;  1O0X A;  5CIK A;  1R5G A;  3TAV A;  4R60 A;  2B3K A;  2GG0 A;  4MAT A;  1QXZ A;  1XGO A;  4S2R P;  1WLR A;  1WL9 A;  4S01 A;  2BWU A;  2B3H A;  3PKA A;  1XGM A;  3MX6 A;  1YW8 A;  2EVO A;  1YVM A;  4U6J A;  5CDL A;  1C23 A;  4U76 A;  5D6F A;  3L7G A;  1QZY A;  3I7M A;  1CHM A;  3O5V A;  3FMR A;  4IF7 A;  1KQ9 A;  3BIQ A;  5CDE A;  5CDV A;  1Y1N A;  2Q94 A;  4QR8 A;  1YW9 A;  4ZWO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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