1WQ1G

Ras-rasgap complex
Total Genus 112
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
320
structure length
320
Chain Sequence
MPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHEKLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQSCELSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRTDLSRDLAALHEICVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Complex (gtp-binding/gtpase activation)
molecule keywords H-RAS
publication title The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
pubmed doi rcsb
source organism Homo sapiens
total genus 112
structure length 320
sequence length 320
ec nomenclature
pdb deposition date 1997-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00616 RasGAP GTPase-activator protein for Ras-like GTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.506.10 Mainly Alpha Orthogonal Bundle GTPase Activation - p120GAP; domain 1 GTPase Activation - p120gap; domain 1 1wq1G01
1.10.506.10 Mainly Alpha Orthogonal Bundle GTPase Activation - p120GAP; domain 1 GTPase Activation - p120gap; domain 1 1wq1G02
3BXJA 3HM6X 1WQ1G 3IG3A 5E6PA 1NF1A 3FAYA 3RYTA 3SU8X 4M8MA 4M8NA 1WERA
chains in the Genus database with same CATH superfamily
3BXJA 3HM6X 1WQ1G 3IG3A 5E6PA 1NF1A 3FAYA 3RYTA 3SU8X 4M8MA 4M8NA 1WERA
chains in the Genus database with same CATH topology
3BXJA 3HM6X 1WQ1G 3IG3A 5E6PA 1NF1A 3FAYA 3RYTA 3SU8X 4M8MA 4M8NA 1WERA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BXJ A;  3HM6 X;  1WQ1 G;  3IG3 A;  5E6P A;  1NF1 A;  3FAY A;  3RYT A;  3SU8 X;  4M8M A;  4M8N A;  1WER A; 
#chains in the Genus database with same CATH topology
 3BXJ A;  3HM6 X;  1WQ1 G;  3IG3 A;  5E6P A;  1NF1 A;  3FAY A;  3RYT A;  3SU8 X;  4M8M A;  4M8N A;  1WER A; 
#chains in the Genus database with same CATH homology
 3BXJ A;  3HM6 X;  1WQ1 G;  3IG3 A;  5E6P A;  1NF1 A;  3FAY A;  3RYT A;  3SU8 X;  4M8M A;  4M8N A;  1WER A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...