1WQKA

Solution structure of apetx1, a specific peptide inhibitor of human ether-a-go-go-related gene potassium channels from the venom of the sea anemone anthopleura elegantissima: a new fold for an herg toxin
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
42
structure length
42
Chain Sequence
GTTCYCGKTIGIYWFGTKTCPSNRGYTGSCGYFLGICCYPVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Toxin APETx1
publication title Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin
pubmed doi rcsb
total genus 4
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2004-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wqkA00
3D4UB 2JTOA 1ATXA 1ZLIB 1WXNA 2SH1A 1D6BA 1SH1A 1AHLA 1ZUEA 1H5OA 2MUBA 1WQKA 1ZLHB 1BDSA 2K2XA 1APFA 1Z99A 3LMSB 1SHIA 1ZUFA 4GV5A 2MN3A 2BDSA 2H9XA 2RNGA 1B8WA
chains in the Genus database with same CATH superfamily
3C30A 1EL6A 2JTOA 2B9KA 3D4UB 1ZLIB 3MYVA 1WXNA 2QSHA 1ATXA 2SH1A 3MCXA 1D6BA 1GL9B 2IKDA 2DLAA 3KEZA 2IKEA 2QSFA 1SH1A 3C38A 3IF4A 1AHLA 4YIRA 1ZUEA 2JR3A 1H5OA 2QSGA 2HJ9C 2MUBA 1WQKA 2HJEA 1ZLHB 1BDSA 2K2XA 1APFA 1GKUB 1Z99A 2XXLA 3LMSB 1SHIA 1ZUFA 4GV5A 2MN3A 1ZHHB 2BDSA 2H9XA 2RNGA 1B8WA
chains in the Genus database with same CATH topology
3C30A 3D4UB 2JTOA 2B9KA 3MYVA 1ZLIB 2QSHA 1WXNA 1ATXA 2SH1A 3MCXA 1D6BA 2IKDA 2DLAA 3KEZA 2IKEA 2QSFA 1SH1A 3C38A 1AHLA 4YIRA 1ZUEA 2JR3A 1H5OA 2QSGA 2HJ9C 2MUBA 1WQKA 2HJEA 1ZLHB 1BDSA 2K2XA 1APFA 1Z99A 2XXLA 3LMSB 1SHIA 1ZUFA 4GV5A 2MN3A 1ZHHB 2BDSA 2H9XA 2RNGA 1B8WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D4U B;  2JTO A;  1ATX A;  1ZLI B;  1WXN A;  2SH1 A;  1D6B A;  1SH1 A;  1AHL A;  1ZUE A;  1H5O A;  2MUB A;  1WQK A;  1ZLH B;  1BDS A;  2K2X A;  1APF A;  1Z99 A;  3LMS B;  1SHI A;  1ZUF A;  4GV5 A;  2MN3 A;  2BDS A;  2H9X A;  2RNG A;  1B8W A; 
#chains in the Genus database with same CATH topology
 3C30 A;  1EL6 A;  2JTO A;  2B9K A;  3D4U B;  1ZLI B;  3MYV A;  1WXN A;  2QSH A;  1ATX A;  2SH1 A;  3MCX A;  1D6B A;  1GL9 B;  2IKD A;  2DLA A;  3KEZ A;  2IKE A;  2QSF A;  1SH1 A;  3C38 A;  3IF4 A;  1AHL A;  4YIR A;  1ZUE A;  2JR3 A;  1H5O A;  2QSG A;  2HJ9 C;  2MUB A;  1WQK A;  2HJE A;  1ZLH B;  1BDS A;  2K2X A;  1APF A;  1GKU B;  1Z99 A;  2XXL A;  3LMS B;  1SHI A;  1ZUF A;  4GV5 A;  2MN3 A;  1ZHH B;  2BDS A;  2H9X A;  2RNG A;  1B8W A; 
#chains in the Genus database with same CATH homology
 3C30 A;  3D4U B;  2JTO A;  2B9K A;  3MYV A;  1ZLI B;  2QSH A;  1WXN A;  1ATX A;  2SH1 A;  3MCX A;  1D6B A;  2IKD A;  2DLA A;  3KEZ A;  2IKE A;  2QSF A;  1SH1 A;  3C38 A;  1AHL A;  4YIR A;  1ZUE A;  2JR3 A;  1H5O A;  2QSG A;  2HJ9 C;  2MUB A;  1WQK A;  2HJE A;  1ZLH B;  1BDS A;  2K2X A;  1APF A;  1Z99 A;  2XXL A;  3LMS B;  1SHI A;  1ZUF A;  4GV5 A;  2MN3 A;  1ZHH B;  2BDS A;  2H9X A;  2RNG A;  1B8W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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