1WQKA

Solution structure of apetx1, a specific peptide inhibitor of human ether-a-go-go-related gene potassium channels from the venom of the sea anemone anthopleura elegantissima: a new fold for an herg toxin
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
42
structure length
42
Chain Sequence
GTTCYCGKTIGIYWFGTKTCPSNRGYTGSCGYFLGICCYPVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin
pubmed doi rcsb
molecule tags Toxin
molecule keywords Toxin APETx1
total genus 4
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2004-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wqkA00
2K2XA 1SHIA 2MUBA 1APFA 2SH1A 1D6BA 1SH1A 1H5OA 1WXNA 1BDSA 2MN3A 3LMSB 2H9XA 1B8WA 1Z99A 1ZUFA 2BDSA 1AHLA 2JTOA 1ATXA 4GV5A 1ZLHB 1ZUEA 1WQKA 3D4UB 2RNGA 1ZLIB
chains in the Genus database with same CATH superfamily
2IKDA 2K2XA 3IF4A 1SHIA 4YIRA 2MUBA 1APFA 3C38A 2SH1A 1D6BA 1SH1A 2HJ9C 1H5OA 1WXNA 1BDSA 2MN3A 3LMSB 2H9XA 2QSFA 3MCXA 1B8WA 3C30A 1Z99A 2IKEA 1ZUFA 2BDSA 3MYVA 1AHLA 2JTOA 2JR3A 2QSGA 1GKUB 1EL6A 1ATXA 2XXLA 1GL9B 2HJEA 1ZHHB 4GV5A 3KEZA 2DLAA 1ZLHB 1ZUEA 2RNGA 1WQKA 3D4UB 2B9KA 1ZLIB 2QSHA
chains in the Genus database with same CATH topology
2IKDA 2K2XA 1SHIA 4YIRA 2MUBA 1APFA 3C38A 2SH1A 1D6BA 1SH1A 2HJ9C 1H5OA 1WXNA 1BDSA 2MN3A 3LMSB 2H9XA 2QSFA 3MCXA 1B8WA 3C30A 1Z99A 2IKEA 1ZUFA 2BDSA 3MYVA 1AHLA 2JTOA 2JR3A 2QSGA 1ATXA 2XXLA 2HJEA 1ZHHB 4GV5A 3KEZA 2DLAA 1ZLHB 1ZUEA 2RNGA 1WQKA 3D4UB 2B9KA 1ZLIB 2QSHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K2X A;  1SHI A;  2MUB A;  1APF A;  2SH1 A;  1D6B A;  1SH1 A;  1H5O A;  1WXN A;  1BDS A;  2MN3 A;  3LMS B;  2H9X A;  1B8W A;  1Z99 A;  1ZUF A;  2BDS A;  1AHL A;  2JTO A;  1ATX A;  4GV5 A;  1ZLH B;  1ZUE A;  1WQK A;  3D4U B;  2RNG A;  1ZLI B; 
#chains in the Genus database with same CATH topology
 2IKD A;  2K2X A;  3IF4 A;  1SHI A;  4YIR A;  2MUB A;  1APF A;  3C38 A;  2SH1 A;  1D6B A;  1SH1 A;  2HJ9 C;  1H5O A;  1WXN A;  1BDS A;  2MN3 A;  3LMS B;  2H9X A;  2QSF A;  3MCX A;  1B8W A;  3C30 A;  1Z99 A;  2IKE A;  1ZUF A;  2BDS A;  3MYV A;  1AHL A;  2JTO A;  2JR3 A;  2QSG A;  1GKU B;  1EL6 A;  1ATX A;  2XXL A;  1GL9 B;  2HJE A;  1ZHH B;  4GV5 A;  3KEZ A;  2DLA A;  1ZLH B;  1ZUE A;  2RNG A;  1WQK A;  3D4U B;  2B9K A;  1ZLI B;  2QSH A; 
#chains in the Genus database with same CATH homology
 2IKD A;  2K2X A;  1SHI A;  4YIR A;  2MUB A;  1APF A;  3C38 A;  2SH1 A;  1D6B A;  1SH1 A;  2HJ9 C;  1H5O A;  1WXN A;  1BDS A;  2MN3 A;  3LMS B;  2H9X A;  2QSF A;  3MCX A;  1B8W A;  3C30 A;  1Z99 A;  2IKE A;  1ZUF A;  2BDS A;  3MYV A;  1AHL A;  2JTO A;  2JR3 A;  2QSG A;  1ATX A;  2XXL A;  2HJE A;  1ZHH B;  4GV5 A;  3KEZ A;  2DLA A;  1ZLH B;  1ZUE A;  2RNG A;  1WQK A;  3D4U B;  2B9K A;  1ZLI B;  2QSH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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