1WR7A

Solution structure of the third ww domain of nedd4-2
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
41
structure length
41
Chain Sequence
GSPGIQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Ligase
molecule keywords Nedd4-2
publication title Solution structures of the WW domains of Nedd4-2
rcsb
source organism Mus musculus
total genus 4
structure length 41
sequence length 41
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1wr7A01
2E45A 2JV4A 2M3OW 3OOBA 2YSIA 2YSBA 2ZAJA 2ZR5A 3KABA 2F21A 3KADA 3WH0A 3KAIA 2DMVA 5CQ2A 2XP4A 2XP8A 3KAGA 3L4HA 2MDIA 4QIBA 2RE3A 2M8JA 2KXQA 2M8IA 1JMQA 3LE4A 2JMFA 1K9QA 2XP6A 2BA1A 2JX8A 3KCEA 2YSGA 2ZQUA 2L4JA 3ODKA 1PINA 1EG3A 4U86A 1WMVA 3TCZA 1YW5A 2ZQSA 2ITKA 1O6WA 2XPBA 1EG4A 3M7NA 3M85A 2YSHA 1TK7A 4U85A 2DJYA 2LAJA 2ZQVA 2YSFA 2XP5A 2EZ5W 5AHTA 2ZR4A 2XP7A 1F8AB 2JXWA 2XPAA 2ZR6A 3TDBA 3KAHA 4REXA 3CNGA 2DWVA 2XP3A 2XP9A 4E5RA 3TC5A 2DK7A 1ZCNA 3KAFA 2ZQTA 4U84A 1I5HW 1NMVA 1K9RA 2DK1A 3NTPA 1WR7A 2Q5AA
chains in the Genus database with same CATH superfamily
2E45A 5E65A 2JV4A 2M3OW 3OOBA 2YSIA 2YSBA 2ZAJA 2ZR5A 3KABA 2F21A 3KADA 4GLXA 3WH0A 3KAIA 2DMVA 5CQ2A 4A0UA 3FSCA 2XP4A 2XP8A 3KAGA 3L4HA 2MDIA 4QIBA 1TR8A 2RE3A 2M8JA 2QRVA 2KXQA 2M8IA 3MQHA 1JMQA 3LE4A 2JMFA 1K9QA 2XP6A 2BA1A 2JX8A 3PQHA 3KCEA 3MCBB 2YSGA 2ZQUA 2L4JA 3ODKA 1PINA 1EG3A 2WADA 4U86A 4A0TA 1WMVA 3TCZA 1RP5A 1YW5A 2ZQSA 3MQGA 2ITKA 1O6WA 5U47A 2XPBA 1EG4A 3M7NA 3M85A 2YSHA 1TK7A 5E62A 4U85A 5E66A 2DJYA 2LAJA 2ZQVA 2YSFA 2XP5A 2EZ5W 5AHTA 2ZR4A 2XP7A 1F8AB 3LKXA 2YAJB 2JXWA 5E5WA 2XPAA 2ZR6A 3TDBA 3KAHA 3MCBA 4REXA 3CNGA 2Y8NB 2DWVA 2WAEA 2XP3A 2XP9A 1FLCA 3FSBA 4E5RA 3TC5A 2OWOA 2DK7A 1ZCNA 5E64A 3KAFA 3LKXB 2ZQTA 4U84A 3FS8A 1I5HW 1NMVA 1K9RA 2DK1A 3NTPA 1WR7A 2Q5AA
chains in the Genus database with same CATH topology
2E45A 5E65A 2JV4A 2M3OW 3OOBA 2YSIA 2YSBA 2ZAJA 2ZR5A 3KABA 2F21A 3KADA 4GLXA 3WH0A 3KAIA 2DMVA 5CQ2A 4A0UA 3FSCA 2XP4A 2XP8A 3KAGA 3L4HA 2MDIA 4QIBA 1TR8A 2RE3A 2M8JA 2QRVA 2KXQA 2M8IA 3MQHA 1JMQA 3LE4A 2JMFA 1K9QA 2XP6A 2BA1A 2JX8A 3PQHA 3KCEA 3MCBB 2YSGA 2ZQUA 2L4JA 3ODKA 1PINA 1EG3A 2WADA 4U86A 4A0TA 1WMVA 3TCZA 1RP5A 1YW5A 2ZQSA 3MQGA 2ITKA 1O6WA 5U47A 2XPBA 1EG4A 3M7NA 3M85A 2YSHA 1TK7A 5E62A 4U85A 5E66A 2DJYA 2LAJA 2ZQVA 2YSFA 2XP5A 2EZ5W 5AHTA 2ZR4A 2XP7A 1F8AB 3LKXA 2YAJB 2JXWA 5E5WA 2XPAA 2ZR6A 3TDBA 3KAHA 3MCBA 4REXA 3CNGA 2Y8NB 2DWVA 2WAEA 2XP3A 2XP9A 1FLCA 3FSBA 4E5RA 3TC5A 2OWOA 2DK7A 1ZCNA 5E64A 3KAFA 3LKXB 2ZQTA 4U84A 3FS8A 1I5HW 1NMVA 1K9RA 2DK1A 3NTPA 1WR7A 2Q5AA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2E45 A;  2JV4 A;  2M3O W;  3OOB A;  2YSI A;  2YSB A;  2ZAJ A;  2ZR5 A;  3KAB A;  2F21 A;  3KAD A;  3WH0 A;  3KAI A;  2DMV A;  5CQ2 A;  2XP4 A;  2XP8 A;  3KAG A;  3L4H A;  2MDI A;  4QIB A;  2RE3 A;  2M8J A;  2KXQ A;  2M8I A;  1JMQ A;  3LE4 A;  2JMF A;  1K9Q A;  2XP6 A;  2BA1 A;  2JX8 A;  3KCE A;  2YSG A;  2ZQU A;  2L4J A;  3ODK A;  1PIN A;  1EG3 A;  4U86 A;  1WMV A;  3TCZ A;  1YW5 A;  2ZQS A;  2ITK A;  1O6W A;  2XPB A;  1EG4 A;  3M7N A;  3M85 A;  2YSH A;  1TK7 A;  4U85 A;  2DJY A;  2LAJ A;  2ZQV A;  2YSF A;  2XP5 A;  2EZ5 W;  5AHT A;  2ZR4 A;  2XP7 A;  1F8A B;  2JXW A;  2XPA A;  2ZR6 A;  3TDB A;  3KAH A;  4REX A;  3CNG A;  2DWV A;  2XP3 A;  2XP9 A;  4E5R A;  3TC5 A;  2DK7 A;  1ZCN A;  3KAF A;  2ZQT A;  4U84 A;  1I5H W;  1NMV A;  1K9R A;  2DK1 A;  3NTP A;  1WR7 A;  2Q5A A; 
#chains in the Genus database with same CATH topology
 2E45 A;  5E65 A;  2JV4 A;  2M3O W;  3OOB A;  2YSI A;  2YSB A;  2ZAJ A;  2ZR5 A;  3KAB A;  2F21 A;  3KAD A;  4GLX A;  3WH0 A;  3KAI A;  2DMV A;  5CQ2 A;  4A0U A;  3FSC A;  2XP4 A;  2XP8 A;  3KAG A;  3L4H A;  2MDI A;  4QIB A;  1TR8 A;  2RE3 A;  2M8J A;  2QRV A;  2KXQ A;  2M8I A;  3MQH A;  1JMQ A;  3LE4 A;  2JMF A;  1K9Q A;  2XP6 A;  2BA1 A;  2JX8 A;  3PQH A;  3KCE A;  3MCB B;  2YSG A;  2ZQU A;  2L4J A;  3ODK A;  1PIN A;  1EG3 A;  2WAD A;  4U86 A;  4A0T A;  1WMV A;  3TCZ A;  1RP5 A;  1YW5 A;  2ZQS A;  3MQG A;  2ITK A;  1O6W A;  5U47 A;  2XPB A;  1EG4 A;  3M7N A;  3M85 A;  2YSH A;  1TK7 A;  5E62 A;  4U85 A;  5E66 A;  2DJY A;  2LAJ A;  2ZQV A;  2YSF A;  2XP5 A;  2EZ5 W;  5AHT A;  2ZR4 A;  2XP7 A;  1F8A B;  3LKX A;  2YAJ B;  2JXW A;  5E5W A;  2XPA A;  2ZR6 A;  3TDB A;  3KAH A;  3MCB A;  4REX A;  3CNG A;  2Y8N B;  2DWV A;  2WAE A;  2XP3 A;  2XP9 A;  1FLC A;  3FSB A;  4E5R A;  3TC5 A;  2OWO A;  2DK7 A;  1ZCN A;  5E64 A;  3KAF A;  3LKX B;  2ZQT A;  4U84 A;  3FS8 A;  1I5H W;  1NMV A;  1K9R A;  2DK1 A;  3NTP A;  1WR7 A;  2Q5A A; 
#chains in the Genus database with same CATH homology
 2E45 A;  5E65 A;  2JV4 A;  2M3O W;  3OOB A;  2YSI A;  2YSB A;  2ZAJ A;  2ZR5 A;  3KAB A;  2F21 A;  3KAD A;  4GLX A;  3WH0 A;  3KAI A;  2DMV A;  5CQ2 A;  4A0U A;  3FSC A;  2XP4 A;  2XP8 A;  3KAG A;  3L4H A;  2MDI A;  4QIB A;  1TR8 A;  2RE3 A;  2M8J A;  2QRV A;  2KXQ A;  2M8I A;  3MQH A;  1JMQ A;  3LE4 A;  2JMF A;  1K9Q A;  2XP6 A;  2BA1 A;  2JX8 A;  3PQH A;  3KCE A;  3MCB B;  2YSG A;  2ZQU A;  2L4J A;  3ODK A;  1PIN A;  1EG3 A;  2WAD A;  4U86 A;  4A0T A;  1WMV A;  3TCZ A;  1RP5 A;  1YW5 A;  2ZQS A;  3MQG A;  2ITK A;  1O6W A;  5U47 A;  2XPB A;  1EG4 A;  3M7N A;  3M85 A;  2YSH A;  1TK7 A;  5E62 A;  4U85 A;  5E66 A;  2DJY A;  2LAJ A;  2ZQV A;  2YSF A;  2XP5 A;  2EZ5 W;  5AHT A;  2ZR4 A;  2XP7 A;  1F8A B;  3LKX A;  2YAJ B;  2JXW A;  5E5W A;  2XPA A;  2ZR6 A;  3TDB A;  3KAH A;  3MCB A;  4REX A;  3CNG A;  2Y8N B;  2DWV A;  2WAE A;  2XP3 A;  2XP9 A;  1FLC A;  3FSB A;  4E5R A;  3TC5 A;  2OWO A;  2DK7 A;  1ZCN A;  5E64 A;  3KAF A;  3LKX B;  2ZQT A;  4U84 A;  3FS8 A;  1I5H W;  1NMV A;  1K9R A;  2DK1 A;  3NTP A;  1WR7 A;  2Q5A A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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