1WR7A

Solution structure of the third ww domain of nedd4-2
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
41
structure length
41
Chain Sequence
GSPGIQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the WW domains of Nedd4-2
rcsb
molecule tags Ligase
source organism Mus musculus
molecule keywords Nedd4-2
total genus 4
structure length 41
sequence length 41
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1wr7A01
1ZCNA 3NTPA 2YSBA 2XP3A 1I5HW 2XP9A 2ZR6A 2E45A 2DMVA 2ITKA 2ZAJA 2JV4A 2LAJA 1K9RA 2DWVA 2JX8A 3L4HA 2JMFA 2M8JA 2XP8A 3TCZA 2MDIA 4QIBA 2KXQA 2ZQUA 5AHTA 3KABA 2XP6A 2XP5A 1F8AB 1YW5A 2M3OW 3KADA 2XP7A 3TDBA 1K9QA 3KAFA 2EZ5W 1WR7A 1EG3A 3ODKA 2YSGA 2XPBA 1NMVA 3KAIA 4U84A 4E5RA 1EG4A 2YSHA 5CQ2A 3M85A 2XPAA 2M8IA 2DJYA 2Q5AA 3TC5A 3OOBA 3CNGA 2ZR5A 3KAHA 2YSFA 2BA1A 3LE4A 3KCEA 4U86A 4REXA 2YSIA 1PINA 1WMVA 1JMQA 2ZQVA 3WH0A 3M7NA 2DK1A 2F21A 2RE3A 2ZR4A 4U85A 3KAGA 2ZQSA 2JXWA 1O6WA 2XP4A 2ZQTA 1TK7A 2L4JA 2DK7A
chains in the Genus database with same CATH superfamily
5E5WA 1ZCNA 3NTPA 2QRVA 2YSBA 2XP3A 1I5HW 2XP9A 2ZR6A 2E45A 2DMVA 2WAEA 2ITKA 2ZAJA 2Y8NB 2JV4A 2LAJA 5U47A 1K9RA 4A0TA 2DWVA 2JX8A 3L4HA 3PQHA 2JMFA 2M8JA 4A0UA 2XP8A 3TCZA 2MDIA 4QIBA 2WADA 2KXQA 2ZQUA 5AHTA 3KABA 5E66A 2XP6A 2XP5A 1RP5A 1F8AB 3KADA 1YW5A 2M3OW 5E62A 2XP7A 3TDBA 1K9QA 3KAFA 2EZ5W 1WR7A 1EG3A 3ODKA 2YSGA 2XPBA 1NMVA 4GLXA 3KAIA 4U84A 4E5RA 3MQGA 1EG4A 2YSHA 3FS8A 5CQ2A 3M85A 2XPAA 2M8IA 1FLCA 2YAJB 2DJYA 2Q5AA 3TC5A 3OOBA 3CNGA 2ZR5A 3LKXA 3KAHA 2YSFA 5E65A 2BA1A 3LE4A 3KCEA 1TR8A 4U86A 4REXA 3MCBA 2YSIA 1PINA 3LKXB 2OWOA 3FSBA 1WMVA 1JMQA 3MCBB 2ZQVA 3WH0A 5E64A 3M7NA 2DK1A 2F21A 2RE3A 2ZR4A 4U85A 3KAGA 2ZQSA 3FSCA 2JXWA 1O6WA 2XP4A 2ZQTA 3MQHA 1TK7A 2L4JA 2DK7A
chains in the Genus database with same CATH topology
5E5WA 1ZCNA 3NTPA 2QRVA 2YSBA 2XP3A 1I5HW 2XP9A 2ZR6A 2E45A 2DMVA 2WAEA 2ITKA 2ZAJA 2Y8NB 2JV4A 2LAJA 5U47A 1K9RA 4A0TA 2DWVA 2JX8A 3L4HA 3PQHA 2JMFA 2M8JA 4A0UA 2XP8A 3TCZA 2MDIA 4QIBA 2WADA 2KXQA 2ZQUA 5AHTA 3KABA 5E66A 2XP6A 2XP5A 1RP5A 1F8AB 3KADA 1YW5A 2M3OW 5E62A 2XP7A 3TDBA 1K9QA 3KAFA 2EZ5W 1WR7A 1EG3A 3ODKA 2YSGA 2XPBA 1NMVA 4GLXA 3KAIA 4U84A 4E5RA 3MQGA 1EG4A 2YSHA 3FS8A 5CQ2A 3M85A 2XPAA 2M8IA 1FLCA 2YAJB 2DJYA 2Q5AA 3TC5A 3OOBA 3CNGA 2ZR5A 3LKXA 3KAHA 2YSFA 5E65A 2BA1A 3LE4A 3KCEA 1TR8A 4U86A 4REXA 3MCBA 2YSIA 1PINA 3LKXB 2OWOA 3FSBA 1WMVA 1JMQA 3MCBB 2ZQVA 3WH0A 5E64A 3M7NA 2DK1A 2F21A 2RE3A 2ZR4A 4U85A 3KAGA 2ZQSA 3FSCA 2JXWA 1O6WA 2XP4A 2ZQTA 3MQHA 1TK7A 2L4JA 2DK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZCN A;  3NTP A;  2YSB A;  2XP3 A;  1I5H W;  2XP9 A;  2ZR6 A;  2E45 A;  2DMV A;  2ITK A;  2ZAJ A;  2JV4 A;  2LAJ A;  1K9R A;  2DWV A;  2JX8 A;  3L4H A;  2JMF A;  2M8J A;  2XP8 A;  3TCZ A;  2MDI A;  4QIB A;  2KXQ A;  2ZQU A;  5AHT A;  3KAB A;  2XP6 A;  2XP5 A;  1F8A B;  1YW5 A;  2M3O W;  3KAD A;  2XP7 A;  3TDB A;  1K9Q A;  3KAF A;  2EZ5 W;  1WR7 A;  1EG3 A;  3ODK A;  2YSG A;  2XPB A;  1NMV A;  3KAI A;  4U84 A;  4E5R A;  1EG4 A;  2YSH A;  5CQ2 A;  3M85 A;  2XPA A;  2M8I A;  2DJY A;  2Q5A A;  3TC5 A;  3OOB A;  3CNG A;  2ZR5 A;  3KAH A;  2YSF A;  2BA1 A;  3LE4 A;  3KCE A;  4U86 A;  4REX A;  2YSI A;  1PIN A;  1WMV A;  1JMQ A;  2ZQV A;  3WH0 A;  3M7N A;  2DK1 A;  2F21 A;  2RE3 A;  2ZR4 A;  4U85 A;  3KAG A;  2ZQS A;  2JXW A;  1O6W A;  2XP4 A;  2ZQT A;  1TK7 A;  2L4J A;  2DK7 A; 
#chains in the Genus database with same CATH topology
 5E5W A;  1ZCN A;  3NTP A;  2QRV A;  2YSB A;  2XP3 A;  1I5H W;  2XP9 A;  2ZR6 A;  2E45 A;  2DMV A;  2WAE A;  2ITK A;  2ZAJ A;  2Y8N B;  2JV4 A;  2LAJ A;  5U47 A;  1K9R A;  4A0T A;  2DWV A;  2JX8 A;  3L4H A;  3PQH A;  2JMF A;  2M8J A;  4A0U A;  2XP8 A;  3TCZ A;  2MDI A;  4QIB A;  2WAD A;  2KXQ A;  2ZQU A;  5AHT A;  3KAB A;  5E66 A;  2XP6 A;  2XP5 A;  1RP5 A;  1F8A B;  3KAD A;  1YW5 A;  2M3O W;  5E62 A;  2XP7 A;  3TDB A;  1K9Q A;  3KAF A;  2EZ5 W;  1WR7 A;  1EG3 A;  3ODK A;  2YSG A;  2XPB A;  1NMV A;  4GLX A;  3KAI A;  4U84 A;  4E5R A;  3MQG A;  1EG4 A;  2YSH A;  3FS8 A;  5CQ2 A;  3M85 A;  2XPA A;  2M8I A;  1FLC A;  2YAJ B;  2DJY A;  2Q5A A;  3TC5 A;  3OOB A;  3CNG A;  2ZR5 A;  3LKX A;  3KAH A;  2YSF A;  5E65 A;  2BA1 A;  3LE4 A;  3KCE A;  1TR8 A;  4U86 A;  4REX A;  3MCB A;  2YSI A;  1PIN A;  3LKX B;  2OWO A;  3FSB A;  1WMV A;  1JMQ A;  3MCB B;  2ZQV A;  3WH0 A;  5E64 A;  3M7N A;  2DK1 A;  2F21 A;  2RE3 A;  2ZR4 A;  4U85 A;  3KAG A;  2ZQS A;  3FSC A;  2JXW A;  1O6W A;  2XP4 A;  2ZQT A;  3MQH A;  1TK7 A;  2L4J A;  2DK7 A; 
#chains in the Genus database with same CATH homology
 5E5W A;  1ZCN A;  3NTP A;  2QRV A;  2YSB A;  2XP3 A;  1I5H W;  2XP9 A;  2ZR6 A;  2E45 A;  2DMV A;  2WAE A;  2ITK A;  2ZAJ A;  2Y8N B;  2JV4 A;  2LAJ A;  5U47 A;  1K9R A;  4A0T A;  2DWV A;  2JX8 A;  3L4H A;  3PQH A;  2JMF A;  2M8J A;  4A0U A;  2XP8 A;  3TCZ A;  2MDI A;  4QIB A;  2WAD A;  2KXQ A;  2ZQU A;  5AHT A;  3KAB A;  5E66 A;  2XP6 A;  2XP5 A;  1RP5 A;  1F8A B;  3KAD A;  1YW5 A;  2M3O W;  5E62 A;  2XP7 A;  3TDB A;  1K9Q A;  3KAF A;  2EZ5 W;  1WR7 A;  1EG3 A;  3ODK A;  2YSG A;  2XPB A;  1NMV A;  4GLX A;  3KAI A;  4U84 A;  4E5R A;  3MQG A;  1EG4 A;  2YSH A;  3FS8 A;  5CQ2 A;  3M85 A;  2XPA A;  2M8I A;  1FLC A;  2YAJ B;  2DJY A;  2Q5A A;  3TC5 A;  3OOB A;  3CNG A;  2ZR5 A;  3LKX A;  3KAH A;  2YSF A;  5E65 A;  2BA1 A;  3LE4 A;  3KCE A;  1TR8 A;  4U86 A;  4REX A;  3MCB A;  2YSI A;  1PIN A;  3LKX B;  2OWO A;  3FSB A;  1WMV A;  1JMQ A;  3MCB B;  2ZQV A;  3WH0 A;  5E64 A;  3M7N A;  2DK1 A;  2F21 A;  2RE3 A;  2ZR4 A;  4U85 A;  3KAG A;  2ZQS A;  3FSC A;  2JXW A;  1O6W A;  2XP4 A;  2ZQT A;  3MQH A;  1TK7 A;  2L4J A;  2DK7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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