1WXNA

Solution structure of apetx2, a specific peptide inhibitor of asic3 proton-gated channels
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
42
structure length
42
Chain Sequence
GTACSCGNSKGIYWFYRPSCPTDRGYTGSCRYFLGTCCTPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Toxin APETx2
publication title Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
pubmed doi rcsb
total genus 6
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2005-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wxnA00
2MUBA 3D4UB 1AHLA 1BDSA 1B8WA 2MN3A 2BDSA 1SH1A 1ZLIB 1ZUFA 2JTOA 2RNGA 1SHIA 1H5OA 3LMSB 2SH1A 1ATXA 2K2XA 1ZLHB 1WXNA 1WQKA 4GV5A 1D6BA 1ZUEA 1Z99A 2H9XA 1APFA
chains in the Genus database with same CATH superfamily
2MUBA 3D4UB 1GL9B 2QSHA 2QSFA 1AHLA 1BDSA 1GKUB 1ZHHB 2MN3A 1B8WA 2BDSA 1SH1A 3MCXA 2QSGA 1ZLIB 1ZUFA 1EL6A 2HJEA 2JTOA 2RNGA 1SHIA 2XXLA 1H5OA 3LMSB 3KEZA 2B9KA 2DLAA 2SH1A 1ATXA 2K2XA 1ZLHB 1WXNA 1WQKA 4YIRA 4GV5A 1D6BA 2IKDA 3MYVA 1ZUEA 2IKEA 3C38A 3IF4A 2JR3A 2HJ9C 1Z99A 3C30A 2H9XA 1APFA
chains in the Genus database with same CATH topology
2MUBA 3D4UB 2QSHA 2QSFA 1AHLA 1BDSA 1B8WA 1ZHHB 2MN3A 2BDSA 1SH1A 3MCXA 2QSGA 1ZLIB 1ZUFA 2HJEA 2JTOA 2RNGA 1SHIA 2XXLA 1H5OA 3LMSB 3KEZA 2B9KA 2DLAA 2SH1A 1ATXA 2K2XA 1ZLHB 1WXNA 1WQKA 4YIRA 4GV5A 1D6BA 2IKDA 3MYVA 1ZUEA 2IKEA 3C38A 2JR3A 2HJ9C 1Z99A 3C30A 2H9XA 1APFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MUB A;  3D4U B;  1AHL A;  1BDS A;  1B8W A;  2MN3 A;  2BDS A;  1SH1 A;  1ZLI B;  1ZUF A;  2JTO A;  2RNG A;  1SHI A;  1H5O A;  3LMS B;  2SH1 A;  1ATX A;  2K2X A;  1ZLH B;  1WXN A;  1WQK A;  4GV5 A;  1D6B A;  1ZUE A;  1Z99 A;  2H9X A;  1APF A; 
#chains in the Genus database with same CATH topology
 2MUB A;  3D4U B;  1GL9 B;  2QSH A;  2QSF A;  1AHL A;  1BDS A;  1GKU B;  1ZHH B;  2MN3 A;  1B8W A;  2BDS A;  1SH1 A;  3MCX A;  2QSG A;  1ZLI B;  1ZUF A;  1EL6 A;  2HJE A;  2JTO A;  2RNG A;  1SHI A;  2XXL A;  1H5O A;  3LMS B;  3KEZ A;  2B9K A;  2DLA A;  2SH1 A;  1ATX A;  2K2X A;  1ZLH B;  1WXN A;  1WQK A;  4YIR A;  4GV5 A;  1D6B A;  2IKD A;  3MYV A;  1ZUE A;  2IKE A;  3C38 A;  3IF4 A;  2JR3 A;  2HJ9 C;  1Z99 A;  3C30 A;  2H9X A;  1APF A; 
#chains in the Genus database with same CATH homology
 2MUB A;  3D4U B;  2QSH A;  2QSF A;  1AHL A;  1BDS A;  1B8W A;  1ZHH B;  2MN3 A;  2BDS A;  1SH1 A;  3MCX A;  2QSG A;  1ZLI B;  1ZUF A;  2HJE A;  2JTO A;  2RNG A;  1SHI A;  2XXL A;  1H5O A;  3LMS B;  3KEZ A;  2B9K A;  2DLA A;  2SH1 A;  1ATX A;  2K2X A;  1ZLH B;  1WXN A;  1WQK A;  4YIR A;  4GV5 A;  1D6B A;  2IKD A;  3MYV A;  1ZUE A;  2IKE A;  3C38 A;  2JR3 A;  2HJ9 C;  1Z99 A;  3C30 A;  2H9X A;  1APF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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