1WXNA

Solution structure of apetx2, a specific peptide inhibitor of asic3 proton-gated channels
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
42
structure length
42
Chain Sequence
GTACSCGNSKGIYWFYRPSCPTDRGYTGSCRYFLGTCCTPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
pubmed doi rcsb
molecule tags Toxin
molecule keywords Toxin APETx2
total genus 6
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2005-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wxnA00
2BDSA 1D6BA 1WXNA 2RNGA 3LMSB 1WQKA 1ATXA 4GV5A 1BDSA 1SH1A 2K2XA 1AHLA 1APFA 1ZUEA 3D4UB 2SH1A 2H9XA 2JTOA 1ZUFA 1ZLIB 2MN3A 1H5OA 1ZLHB 1Z99A 1SHIA 1B8WA 2MUBA
chains in the Genus database with same CATH superfamily
1ZHHB 2BDSA 2IKDA 1D6BA 1WXNA 2RNGA 1GL9B 2HJ9C 2QSHA 3LMSB 1WQKA 2QSFA 4GV5A 1ATXA 2JR3A 1BDSA 1GKUB 1SH1A 2DLAA 2IKEA 4YIRA 2HJEA 2QSGA 2K2XA 1AHLA 2XXLA 1APFA 1ZUEA 3D4UB 2SH1A 2H9XA 2JTOA 1ZUFA 3MYVA 1ZLIB 2MN3A 3KEZA 1H5OA 2B9KA 1EL6A 3C38A 1ZLHB 1Z99A 3MCXA 1SHIA 3C30A 1B8WA 2MUBA 3IF4A
chains in the Genus database with same CATH topology
1ZHHB 2BDSA 2IKDA 1D6BA 1WXNA 2RNGA 2HJ9C 2QSHA 3LMSB 1WQKA 2QSFA 4GV5A 1ATXA 2JR3A 1BDSA 1SH1A 2DLAA 2IKEA 4YIRA 2HJEA 2QSGA 2K2XA 1AHLA 2XXLA 1APFA 1ZUEA 3D4UB 2SH1A 2H9XA 2JTOA 1ZUFA 3MYVA 1ZLIB 2MN3A 3KEZA 1H5OA 2B9KA 3C38A 1ZLHB 1Z99A 3MCXA 1SHIA 3C30A 1B8WA 2MUBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BDS A;  1D6B A;  1WXN A;  2RNG A;  3LMS B;  1WQK A;  1ATX A;  4GV5 A;  1BDS A;  1SH1 A;  2K2X A;  1AHL A;  1APF A;  1ZUE A;  3D4U B;  2SH1 A;  2H9X A;  2JTO A;  1ZUF A;  1ZLI B;  2MN3 A;  1H5O A;  1ZLH B;  1Z99 A;  1SHI A;  1B8W A;  2MUB A; 
#chains in the Genus database with same CATH topology
 1ZHH B;  2BDS A;  2IKD A;  1D6B A;  1WXN A;  2RNG A;  1GL9 B;  2HJ9 C;  2QSH A;  3LMS B;  1WQK A;  2QSF A;  4GV5 A;  1ATX A;  2JR3 A;  1BDS A;  1GKU B;  1SH1 A;  2DLA A;  2IKE A;  4YIR A;  2HJE A;  2QSG A;  2K2X A;  1AHL A;  2XXL A;  1APF A;  1ZUE A;  3D4U B;  2SH1 A;  2H9X A;  2JTO A;  1ZUF A;  3MYV A;  1ZLI B;  2MN3 A;  3KEZ A;  1H5O A;  2B9K A;  1EL6 A;  3C38 A;  1ZLH B;  1Z99 A;  3MCX A;  1SHI A;  3C30 A;  1B8W A;  2MUB A;  3IF4 A; 
#chains in the Genus database with same CATH homology
 1ZHH B;  2BDS A;  2IKD A;  1D6B A;  1WXN A;  2RNG A;  2HJ9 C;  2QSH A;  3LMS B;  1WQK A;  2QSF A;  4GV5 A;  1ATX A;  2JR3 A;  1BDS A;  1SH1 A;  2DLA A;  2IKE A;  4YIR A;  2HJE A;  2QSG A;  2K2X A;  1AHL A;  2XXL A;  1APF A;  1ZUE A;  3D4U B;  2SH1 A;  2H9X A;  2JTO A;  1ZUF A;  3MYV A;  1ZLI B;  2MN3 A;  3KEZ A;  1H5O A;  2B9K A;  3C38 A;  1ZLH B;  1Z99 A;  3MCX A;  1SHI A;  3C30 A;  1B8W A;  2MUB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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