1X0AA

Crystal structure of type ii malate/lactate dehydrogenase from thermus thermophilus hb8
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
344
structure length
344
Chain Sequence
MRWRADFLSAWAEALLRKAGADEPSAKAVAWALVEADLRGVGSHGLLRLPVYVRRLEAGLVNPSPTLPLEERGPVALLDGEHGFGPRVALKAVEAAQSLARRHGLGAVGVRRSTHFGMAGLYAEKLAREGFVAWVTTNAEPDVVPFGGREKALGTNPLAFAAPAPQGILVADLATSESAMGKVFLAREKGERIPPSWGVDREGSPTDDPHRVYALRPLGGPKGYALALLVEVLSGVLTGAGVAHGIGRMYDEWDRPQDVGHFLLALDPGRFVGKEAFLERMGALWQALKATPPAPGHEEVFLPGELEARRRERALAEGMALPERVVAELKALGERYGVPWRDDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8
rcsb
source organism Thermus thermophilus
molecule tags Oxidoreductase
molecule keywords malate/L-lactate dehydrogenase family protein
total genus 115
structure length 344
sequence length 344
ec nomenclature ec 1.1.1.27: L-lactate dehydrogenase.
pdb deposition date 2005-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1x0aA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1x0aA02
1VBIA 3I0PA 1WTJA 4FJUA 4H8AA 3UOEA 1XRHA 2G8YA 2X06A 2CWHA 1V9NA 1Z2IA 1NXUA 1S20A 1X0AA 2CWFA 4FJSA
chains in the Genus database with same CATH superfamily
2FPHX 4JI1H 5A2QW 1NXUA 2LRRA 1DTJA 3KDKA 4LFBH 1WHRA 5K36G 2CPMA 4FJUA 2FMRA 3QD7X 4LF5H 1HNZH 4KHPH 3NCVA 4JYAH 4G08A 2CTEA 2P2RA 4NXMH 1N32H 1N33H 4NZTM 5DT9A 4DV6H 4JVYA 4DR3H 2UXDH 4LFCH 2O4CA 4B3SH 5JEAG 4JI8H 1MSZA 2OPVA 5BR8H 1F0XA 3OETA 4X65H 4X66H 4B3TH 4IFDG 1HR0H 4GKJH 4AQYH 4QMFB 5LL6b 4LF9H 2ANNA 3AEVB 4JI6H 2QNDA 1ODHA 1N34H 1HNWH 2LTMA 2CPQA 3J81W 2DGRA 1IBKH 2HHHH 2JVZA 4PDBA 4OO1G 4JI2H 4LIJA 2M8WA 2Y3MA 2JE6I 2PQUA 4DR5H 1TUAA 1VIGA 4JI7H 1HNXH 1X4MA 4FJSA 1J5EH 1S20A 4OD6A 4GKKH 1XMOH 3T1HH 1X9ZA 4DV4H 4B8CD 2ANRA 2UUBH 4DR6H 5IT9W 3OTOH 4BA2I 2CTKA 3FAUA 4YHHH 4LF8H 2CTJA 4JVHA 2FFMA 2JEBI 3RF2A 2HH2A 2YQRA 4AIMA 3J80W 3GKUA 4DUZH 4DR1H 2AXYA 3OSSD 1FKAH 2UXCH 1Z2IA 4JI5H 4WANA 4BA1I 2ZQEA 1KHMA 1AN7A 4JI4H 2LTLA 4LF6H 4LF4H 1WTJA 1ZTGA 3T1YH 2UU9H 2JEAI 2D9IA 1XNRH 1I94H 2JZXA 1J4WA 2VQFH 2HH3A 1XMQH 4NXNH 4LFAH 1J5KA 4DUYH 1I6UA 1DT4A 4B3MH 1ZZKA 2CTMA 1N36H 3JAMW 4YY3H 4DV5H 3VKEA 1XNQH 1VIHA 5FLXW 4E9JA 1VBIA 1IBMH 2E5LH 4OX9H 3J7AK 2PT7G 4B3RH 2CTFA 2A1SA 1ZZIA 1PQXA 2E3UA 2K1HA 1IBLH 3EZJA 1SEIA 3L7ZC 1WVNA 2PY9A 4NZRM 5LMUH 1K1GA 4DR4H 2BA0A 5LMNH 4K0KH 2NN6G 2CWHA 2CWFA 3GABA 3I0PA 3SB1A 4WALA 4DV1H 2MJHA 1WE8A 4DR7H 1ZZJA 4JI0H 4LF7H 1XRHA 4DV2H 4EC5A 3GR5A 2X06A 1X0AA 2ZM6H 4DV3H 4DV0H 2UUCH 4JI3H 5C0XG 4DR2H 3KDGA 2JA9A 3V69A 2UUAH 4AM3A 4X62H 4OCHA 2OPUA 4NBQA 4H8AA 3UOEA 4X64H 2CTLA 1FJGH 1V9NA 1X4NA 2BL5A 2LF0A 2VQEH 2UXBH 3U1KA 4JV5H 5IWAH 2Z0SA 2M6QA 4DV7H 2G8YA 2VKCA 1UG8A 2F4VH 1EC6A 1S03G 4B8TA 1V8CA
chains in the Genus database with same CATH topology
1VBIA 3I0PA 1WTJA 4FJUA 4H8AA 3UOEA 1XRHA 2G8YA 2X06A 2CWHA 1V9NA 1Z2IA 1NXUA 1S20A 1X0AA 2CWFA 4FJSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VBI A;  3I0P A;  1WTJ A;  4FJU A;  4H8A A;  3UOE A;  1XRH A;  2G8Y A;  2X06 A;  2CWH A;  1V9N A;  1Z2I A;  1NXU A;  1S20 A;  1X0A A;  2CWF A;  4FJS A; 
#chains in the Genus database with same CATH topology
 2FPH X;  4JI1 H;  5A2Q W;  1NXU A;  2LRR A;  1DTJ A;  3KDK A;  4LFB H;  1WHR A;  5K36 G;  2CPM A;  4FJU A;  2FMR A;  3QD7 X;  4LF5 H;  1HNZ H;  4KHP H;  3NCV A;  4JYA H;  4G08 A;  2CTE A;  2P2R A;  4NXM H;  1N32 H;  1N33 H;  4NZT M;  5DT9 A;  4DV6 H;  4JVY A;  4DR3 H;  2UXD H;  4LFC H;  2O4C A;  4B3S H;  5JEA G;  4JI8 H;  1MSZ A;  2OPV A;  5BR8 H;  1F0X A;  3OET A;  4X65 H;  4X66 H;  4B3T H;  4IFD G;  1HR0 H;  4GKJ H;  4AQY H;  4QMF B;  5LL6 b;  4LF9 H;  2ANN A;  3AEV B;  4JI6 H;  2QND A;  1ODH A;  1N34 H;  1HNW H;  2LTM A;  2CPQ A;  3J81 W;  2DGR A;  1IBK H;  2HHH H;  2JVZ A;  4PDB A;  4OO1 G;  4JI2 H;  4LIJ A;  2M8W A;  2Y3M A;  2JE6 I;  2PQU A;  4DR5 H;  1TUA A;  1VIG A;  4JI7 H;  1HNX H;  1X4M A;  4FJS A;  1J5E H;  1S20 A;  4OD6 A;  4GKK H;  1XMO H;  3T1H H;  1X9Z A;  4DV4 H;  4B8C D;  2ANR A;  2UUB H;  4DR6 H;  5IT9 W;  3OTO H;  4BA2 I;  2CTK A;  3FAU A;  4YHH H;  4LF8 H;  2CTJ A;  4JVH A;  2FFM A;  2JEB I;  3RF2 A;  2HH2 A;  2YQR A;  4AIM A;  3J80 W;  3GKU A;  4DUZ H;  4DR1 H;  2AXY A;  3OSS D;  1FKA H;  2UXC H;  1Z2I A;  4JI5 H;  4WAN A;  4BA1 I;  2ZQE A;  1KHM A;  1AN7 A;  4JI4 H;  2LTL A;  4LF6 H;  4LF4 H;  1WTJ A;  1ZTG A;  3T1Y H;  2UU9 H;  2JEA I;  2D9I A;  1XNR H;  1I94 H;  2JZX A;  1J4W A;  2VQF H;  2HH3 A;  1XMQ H;  4NXN H;  4LFA H;  1J5K A;  4DUY H;  1I6U A;  1DT4 A;  4B3M H;  1ZZK A;  2CTM A;  1N36 H;  3JAM W;  4YY3 H;  4DV5 H;  3VKE A;  1XNQ H;  1VIH A;  5FLX W;  4E9J A;  1VBI A;  1IBM H;  2E5L H;  4OX9 H;  3J7A K;  2PT7 G;  4B3R H;  2CTF A;  2A1S A;  1ZZI A;  1PQX A;  2E3U A;  2K1H A;  1IBL H;  3EZJ A;  1SEI A;  3L7Z C;  1WVN A;  2PY9 A;  4NZR M;  5LMU H;  1K1G A;  4DR4 H;  2BA0 A;  5LMN H;  4K0K H;  2NN6 G;  2CWH A;  2CWF A;  3GAB A;  3I0P A;  3SB1 A;  4WAL A;  4DV1 H;  2MJH A;  1WE8 A;  4DR7 H;  1ZZJ A;  4JI0 H;  4LF7 H;  1XRH A;  4DV2 H;  4EC5 A;  3GR5 A;  2X06 A;  1X0A A;  2ZM6 H;  4DV3 H;  4DV0 H;  2UUC H;  4JI3 H;  5C0X G;  4DR2 H;  3KDG A;  2JA9 A;  3V69 A;  2UUA H;  4AM3 A;  4X62 H;  4OCH A;  2OPU A;  4NBQ A;  4H8A A;  3UOE A;  4X64 H;  2CTL A;  1FJG H;  1V9N A;  1X4N A;  2BL5 A;  2LF0 A;  2VQE H;  2UXB H;  3U1K A;  4JV5 H;  5IWA H;  2Z0S A;  2M6Q A;  4DV7 H;  2G8Y A;  2VKC A;  1UG8 A;  2F4V H;  1EC6 A;  1S03 G;  4B8T A;  1V8C A; 
#chains in the Genus database with same CATH homology
 1VBI A;  3I0P A;  1WTJ A;  4FJU A;  4H8A A;  3UOE A;  1XRH A;  2G8Y A;  2X06 A;  2CWH A;  1V9N A;  1Z2I A;  1NXU A;  1S20 A;  1X0A A;  2CWF A;  4FJS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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