1X0AA

Crystal structure of type ii malate/lactate dehydrogenase from thermus thermophilus hb8
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
344
structure length
344
Chain Sequence
b'MRWRADFLSAWAEALLRKAGADEPSAKAVAWALVEADLRGVGSHGLLRLPVYVRRLEAGLVNPSPTLPLEERGPVALLDGEHGFGPRVALKAVEAAQSLARRHGLGAVGVRRSTHFGMAGLYAEKLAREGFVAWVTTNAEPDVVPFGGREKALGTNPLAFAAPAPQGILVADLATSESAMGKVFLAREKGERIPPSWGVDREGSPTDDPHRVYALRPLGGPKGYALALLVEVLSGVLTGAGVAHGIGRMYDEWDRPQDVGHFLLALDPGRFVGKEAFLERMGALWQALKATPPAPGHEEVFLPGELEARRRERALAEGMALPERVVAELKALGERYGVPWRDDA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords malate/L-lactate dehydrogenase family protein
molecule tags Oxidoreductase
source organism Thermus thermophilus
publication title Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8
rcsb
total genus 115
structure length 344
sequence length 344
ec nomenclature ec 1.1.1.27: L-lactate dehydrogenase.
pdb deposition date 2005-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1x0aA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1x0aA02
4FJUA 1Z2IA 1V9NA 1XRHA 2CWHA 1WTJA 1S20A 2G8YA 1X0AA 2CWFA 2X06A 4FJSA 3I0PA 1NXUA 3UOEA 1VBIA 4H8AA
chains in the Genus database with same CATH superfamily
2VQEH 3U1KA 2AXYA 1XRHA 3J81W 2FFMA 4LF9H 3AEVB 4DR5H 2UUCH 4DV0H 2P2RA 1V9NA 4OO1G 2FPHX 1N34H 4B3RH 2YQRA 1DT4A 3UOEA 2LTMA 3J7AK 1WE8A 2M8WA 4DV5H 1S20A 4LF5H 4JI0H 1N32H 1XNRH 4X65H 1J4WA 2E5LH 1SEIA 2PY9A 1AN7A 3JAMW 2JZXA 2CTJA 4X62H 4X66H 1HNXH 2F4VH 1HNWH 2E3UA 4JV5H 1VIGA 4JI3H 4LF6H 1MSZA 5FLXW 1N36H 1X4NA 4OX9H 2CTFA 1PQXA 4JI5H 4LF8H 4DR4H 2ZQEA 4X64H 2K1HA 3GR5A 1ZZIA 1IBMH 4NZRM 2HH2A 1K1GA 1NXUA 3GABA 2CTLA 3RF2A 2QNDA 1F0XA 2UXBH 2PT7G 4NBQA 2UXCH 4KHPH 1XNQH 1WTJA 2M6QA 4DV1H 4GKJH 2CWFA 4JI6H 4AIMA 4B3SH 5A2QW 2VQFH 4FJUA 3FAUA 2JA9A 4NXMH 2CTKA 2CPMA 2BA0A 5IWAH 4B3TH 4JI1H 4FJSA 2Y3MA 5LMUH 2UXDH 3EZJA 2LTLA 4LFAH 4OD6A 3T1HH 4JVHA 1WHRA 2NN6G 2CWHA 2UU9H 2HH3A 4JYAH 3QD7X 1IBKH 1J5KA 4YY3H 2X06A 4DUYH 1TUAA 1X4MA 2PQUA 3KDGA 4B3MH 1S03G 1DTJA 4LF7H 5BR8H 1ZZKA 4WALA 2UUBH 2HHHH 4DUZH 1VBIA 4H8AA 1IBLH 2OPVA 2CPQA 2Z0SA 2MJHA 4DR6H 2BL5A 2FMRA 1FJGH 1X9ZA 1X0AA 2LRRA 4JI4H 4DR2H 4B8CD 3NCVA 2ANNA 4DV3H 4DV2H 4BA2I 4EC5A 5LMNH 4DV6H 4JI7H 2UUAH 4LFBH 4PDBA 3T1YH 1WVNA 2ANRA 1I6UA 4QMFB 5JEAG 4JI8H 1UG8A 3OTOH 1J5EH 2CTMA 3I0PA 4DR1H 1V8CA 1KHMA 4GKKH 4K0KH 1FKAH 2G8YA 1ZZJA 1ODHA 4DV7H 1ZTGA 1EC6A 1XMQH 4YHHH 4AM3A 4LFCH 4DV4H 4BA1I 4AQYH 4JI2H 1HNZH 2JEBI 4WANA 2D9IA 1HR0H 4NXNH 3OSSD 5LL6b 4IFDG 3KDKA 1Z2IA 2VKCA 2DGRA 3SB1A 3V69A 2OPUA 3J80W 4B8TA 1VIHA 2LF0A 3GKUA 4E9JA 3VKEA 1I94H 2JEAI 4NZTM 4DR7H 1N33H 2A1SA 2ZM6H 4JVYA 3OETA 2JE6I 2CTEA 5C0XG 4LF4H 5IT9W 3L7ZC 4DR3H 2O4CA 4OCHA 5K36G 4G08A 2JVZA 4LIJA 1XMOH 5DT9A
chains in the Genus database with same CATH topology
4FJUA 1Z2IA 1V9NA 1XRHA 2CWHA 1WTJA 1S20A 2G8YA 1X0AA 2CWFA 2X06A 4FJSA 3I0PA 1NXUA 3UOEA 1VBIA 4H8AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FJU A;  1Z2I A;  1V9N A;  1XRH A;  2CWH A;  1WTJ A;  1S20 A;  2G8Y A;  1X0A A;  2CWF A;  2X06 A;  4FJS A;  3I0P A;  1NXU A;  3UOE A;  1VBI A;  4H8A A; 
#chains in the Genus database with same CATH topology
 2VQE H;  3U1K A;  2AXY A;  1XRH A;  3J81 W;  2FFM A;  4LF9 H;  3AEV B;  4DR5 H;  2UUC H;  4DV0 H;  2P2R A;  1V9N A;  4OO1 G;  2FPH X;  1N34 H;  4B3R H;  2YQR A;  1DT4 A;  3UOE A;  2LTM A;  3J7A K;  1WE8 A;  2M8W A;  4DV5 H;  1S20 A;  4LF5 H;  4JI0 H;  1N32 H;  1XNR H;  4X65 H;  1J4W A;  2E5L H;  1SEI A;  2PY9 A;  1AN7 A;  3JAM W;  2JZX A;  2CTJ A;  4X62 H;  4X66 H;  1HNX H;  2F4V H;  1HNW H;  2E3U A;  4JV5 H;  1VIG A;  4JI3 H;  4LF6 H;  1MSZ A;  5FLX W;  1N36 H;  1X4N A;  4OX9 H;  2CTF A;  1PQX A;  4JI5 H;  4LF8 H;  4DR4 H;  2ZQE A;  4X64 H;  2K1H A;  3GR5 A;  1ZZI A;  1IBM H;  4NZR M;  2HH2 A;  1K1G A;  1NXU A;  3GAB A;  2CTL A;  3RF2 A;  2QND A;  1F0X A;  2UXB H;  2PT7 G;  4NBQ A;  2UXC H;  4KHP H;  1XNQ H;  1WTJ A;  2M6Q A;  4DV1 H;  4GKJ H;  2CWF A;  4JI6 H;  4AIM A;  4B3S H;  5A2Q W;  2VQF H;  4FJU A;  3FAU A;  2JA9 A;  4NXM H;  2CTK A;  2CPM A;  2BA0 A;  5IWA H;  4B3T H;  4JI1 H;  4FJS A;  2Y3M A;  5LMU H;  2UXD H;  3EZJ A;  2LTL A;  4LFA H;  4OD6 A;  3T1H H;  4JVH A;  1WHR A;  2NN6 G;  2CWH A;  2UU9 H;  2HH3 A;  4JYA H;  3QD7 X;  1IBK H;  1J5K A;  4YY3 H;  2X06 A;  4DUY H;  1TUA A;  1X4M A;  2PQU A;  3KDG A;  4B3M H;  1S03 G;  1DTJ A;  4LF7 H;  5BR8 H;  1ZZK A;  4WAL A;  2UUB H;  2HHH H;  4DUZ H;  1VBI A;  4H8A A;  1IBL H;  2OPV A;  2CPQ A;  2Z0S A;  2MJH A;  4DR6 H;  2BL5 A;  2FMR A;  1FJG H;  1X9Z A;  1X0A A;  2LRR A;  4JI4 H;  4DR2 H;  4B8C D;  3NCV A;  2ANN A;  4DV3 H;  4DV2 H;  4BA2 I;  4EC5 A;  5LMN H;  4DV6 H;  4JI7 H;  2UUA H;  4LFB H;  4PDB A;  3T1Y H;  1WVN A;  2ANR A;  1I6U A;  4QMF B;  5JEA G;  4JI8 H;  1UG8 A;  3OTO H;  1J5E H;  2CTM A;  3I0P A;  4DR1 H;  1V8C A;  1KHM A;  4GKK H;  4K0K H;  1FKA H;  2G8Y A;  1ZZJ A;  1ODH A;  4DV7 H;  1ZTG A;  1EC6 A;  1XMQ H;  4YHH H;  4AM3 A;  4LFC H;  4DV4 H;  4BA1 I;  4AQY H;  4JI2 H;  1HNZ H;  2JEB I;  4WAN A;  2D9I A;  1HR0 H;  4NXN H;  3OSS D;  5LL6 b;  4IFD G;  3KDK A;  1Z2I A;  2VKC A;  2DGR A;  3SB1 A;  3V69 A;  2OPU A;  3J80 W;  4B8T A;  1VIH A;  2LF0 A;  3GKU A;  4E9J A;  3VKE A;  1I94 H;  2JEA I;  4NZT M;  4DR7 H;  1N33 H;  2A1S A;  2ZM6 H;  4JVY A;  3OET A;  2JE6 I;  2CTE A;  5C0X G;  4LF4 H;  5IT9 W;  3L7Z C;  4DR3 H;  2O4C A;  4OCH A;  5K36 G;  4G08 A;  2JVZ A;  4LIJ A;  1XMO H;  5DT9 A; 
#chains in the Genus database with same CATH homology
 4FJU A;  1Z2I A;  1V9N A;  1XRH A;  2CWH A;  1WTJ A;  1S20 A;  2G8Y A;  1X0A A;  2CWF A;  2X06 A;  4FJS A;  3I0P A;  1NXU A;  3UOE A;  1VBI A;  4H8A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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