1X0AA

Crystal structure of type ii malate/lactate dehydrogenase from thermus thermophilus hb8
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
344
structure length
344
Chain Sequence
b'MRWRADFLSAWAEALLRKAGADEPSAKAVAWALVEADLRGVGSHGLLRLPVYVRRLEAGLVNPSPTLPLEERGPVALLDGEHGFGPRVALKAVEAAQSLARRHGLGAVGVRRSTHFGMAGLYAEKLAREGFVAWVTTNAEPDVVPFGGREKALGTNPLAFAAPAPQGILVADLATSESAMGKVFLAREKGERIPPSWGVDREGSPTDDPHRVYALRPLGGPKGYALALLVEVLSGVLTGAGVAHGIGRMYDEWDRPQDVGHFLLALDPGRFVGKEAFLERMGALWQALKATPPAPGHEEVFLPGELEARRRERALAEGMALPERVVAELKALGERYGVPWRDDA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords malate/L-lactate dehydrogenase family protein
publication title Crystal Structure of type II malate/lactate dehydrogenase from thermus thermophilus HB8
rcsb
source organism Thermus thermophilus
molecule tags Oxidoreductase
total genus 115
structure length 344
sequence length 344
ec nomenclature ec 1.1.1.27: L-lactate dehydrogenase.
pdb deposition date 2005-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1x0aA01
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1x0aA02
4H8AA 1Z2IA 2G8YA 3I0PA 1WTJA 1X0AA 4FJUA 1NXUA 1XRHA 1V9NA 3UOEA 4FJSA 1S20A 2CWHA 1VBIA 2X06A 2CWFA
chains in the Genus database with same CATH superfamily
3GR5A 3J81W 3J80W 5A2QW 1UG8A 4NXMH 2M6QA 2O4CA 5JEAG 4DV3H 1IBKH 3OTOH 4B3SH 4B3TH 2JEAI 1S20A 3OETA 4IFDG 2JA9A 4DV6H 1KHMA 4B8CD 4NBQA 4X65H 3J7AK 4NZTM 1N33H 4DR2H 4AIMA 2X06A 4DV5H 4DV7H 2JVZA 3EZJA 1J4WA 1ZZKA 2LTLA 2UUCH 3QD7X 1ODHA 1EC6A 1WE8A 2UXBH 1XMQH 1I94H 4WANA 4JI3H 2NN6G 2ZM6H 3T1HH 1J5EH 4JI7H 4JI6H 4LF4H 2MJHA 3I0PA 1FJGH 4B3MH 4JI0H 3AEVB 1XRHA 2UXCH 1V9NA 2Y3MA 4OCHA 2VKCA 2A1SA 3U1KA 1DTJA 2F4VH 4DR5H 4LF6H 2DGRA 2CTMA 4JI2H 2BL5A 2VQFH 1SEIA 2FFMA 4BA1I 3JAMW 3OSSD 4DV0H 2HHHH 2ANNA 5LMNH 4WALA 1HR0H 2M8WA 1DT4A 2JEBI 1WHRA 1V8CA 3VKEA 4LFCH 1HNWH 4JV5H 4H8AA 4JI8H 4LF9H 1X0AA 2HH2A 4X64H 1VIGA 4DR6H 3UOEA 2LTMA 4DUYH 4LF8H 4JYAH 4LFBH 2PQUA 1X4NA 5IWAH 1J5KA 5LMUH 1IBLH 4OX9H 3FAUA 4JVYA 2CTLA 4FJUA 4AM3A 4B3RH 4BA2I 1MSZA 1IBMH 3T1YH 1S03G 3KDGA 4NXNH 4GKKH 4DR4H 1WVNA 3GABA 4LFAH 3KDKA 1HNZH 2AXYA 2LRRA 2BA0A 2D9IA 5DT9A 3V69A 1XNQH 4JVHA 4X66H 4LF7H 2UXDH 4FJSA 4QMFB 4JI4H 4OD6A 1WTJA 1NXUA 2OPVA 2CTKA 2ANRA 1VBIA 3SB1A 1XNRH 2K1HA 2FMRA 1X9ZA 5K36G 2CTFA 4LIJA 1K1GA 4DV2H 1N34H 4DR1H 4B8TA 2OPUA 4X62H 2LF0A 2JZXA 5C0XG 1XMOH 1F0XA 4DR3H 2PT7G 4JI1H 1Z2IA 1VIHA 3RF2A 4DV1H 4DR7H 4NZRM 2UUBH 2P2RA 1HNXH 4AQYH 2HH3A 2UU9H 4LF5H 5BR8H 4K0KH 2YQRA 4YY3H 4KHPH 2JE6I 5FLXW 2CPQA 1ZTGA 1N32H 2CPMA 1N36H 1PQXA 3GKUA 2Z0SA 2VQEH 2G8YA 4E9JA 1X4MA 4JI5H 1I6UA 1ZZJA 4YHHH 2ZQEA 2QNDA 4DUZH 4GKJH 3NCVA 2CWHA 2CWFA 2E3UA 3L7ZC 4EC5A 4DV4H 2CTEA 2E5LH 5LL6b 2PY9A 1ZZIA 4OO1G 1TUAA 2CTJA 1FKAH 2UUAH 4PDBA 5IT9W 4G08A 1AN7A 2FPHX
chains in the Genus database with same CATH topology
4H8AA 1Z2IA 2G8YA 3I0PA 1WTJA 1X0AA 4FJUA 1NXUA 1XRHA 1V9NA 3UOEA 4FJSA 1S20A 2CWHA 1VBIA 2X06A 2CWFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H8A A;  1Z2I A;  2G8Y A;  3I0P A;  1WTJ A;  1X0A A;  4FJU A;  1NXU A;  1XRH A;  1V9N A;  3UOE A;  4FJS A;  1S20 A;  2CWH A;  1VBI A;  2X06 A;  2CWF A; 
#chains in the Genus database with same CATH topology
 3GR5 A;  3J81 W;  3J80 W;  5A2Q W;  1UG8 A;  4NXM H;  2M6Q A;  2O4C A;  5JEA G;  4DV3 H;  1IBK H;  3OTO H;  4B3S H;  4B3T H;  2JEA I;  1S20 A;  3OET A;  4IFD G;  2JA9 A;  4DV6 H;  1KHM A;  4B8C D;  4NBQ A;  4X65 H;  3J7A K;  4NZT M;  1N33 H;  4DR2 H;  4AIM A;  2X06 A;  4DV5 H;  4DV7 H;  2JVZ A;  3EZJ A;  1J4W A;  1ZZK A;  2LTL A;  2UUC H;  3QD7 X;  1ODH A;  1EC6 A;  1WE8 A;  2UXB H;  1XMQ H;  1I94 H;  4WAN A;  4JI3 H;  2NN6 G;  2ZM6 H;  3T1H H;  1J5E H;  4JI7 H;  4JI6 H;  4LF4 H;  2MJH A;  3I0P A;  1FJG H;  4B3M H;  4JI0 H;  3AEV B;  1XRH A;  2UXC H;  1V9N A;  2Y3M A;  4OCH A;  2VKC A;  2A1S A;  3U1K A;  1DTJ A;  2F4V H;  4DR5 H;  4LF6 H;  2DGR A;  2CTM A;  4JI2 H;  2BL5 A;  2VQF H;  1SEI A;  2FFM A;  4BA1 I;  3JAM W;  3OSS D;  4DV0 H;  2HHH H;  2ANN A;  5LMN H;  4WAL A;  1HR0 H;  2M8W A;  1DT4 A;  2JEB I;  1WHR A;  1V8C A;  3VKE A;  4LFC H;  1HNW H;  4JV5 H;  4H8A A;  4JI8 H;  4LF9 H;  1X0A A;  2HH2 A;  4X64 H;  1VIG A;  4DR6 H;  3UOE A;  2LTM A;  4DUY H;  4LF8 H;  4JYA H;  4LFB H;  2PQU A;  1X4N A;  5IWA H;  1J5K A;  5LMU H;  1IBL H;  4OX9 H;  3FAU A;  4JVY A;  2CTL A;  4FJU A;  4AM3 A;  4B3R H;  4BA2 I;  1MSZ A;  1IBM H;  3T1Y H;  1S03 G;  3KDG A;  4NXN H;  4GKK H;  4DR4 H;  1WVN A;  3GAB A;  4LFA H;  3KDK A;  1HNZ H;  2AXY A;  2LRR A;  2BA0 A;  2D9I A;  5DT9 A;  3V69 A;  1XNQ H;  4JVH A;  4X66 H;  4LF7 H;  2UXD H;  4FJS A;  4QMF B;  4JI4 H;  4OD6 A;  1WTJ A;  1NXU A;  2OPV A;  2CTK A;  2ANR A;  1VBI A;  3SB1 A;  1XNR H;  2K1H A;  2FMR A;  1X9Z A;  5K36 G;  2CTF A;  4LIJ A;  1K1G A;  4DV2 H;  1N34 H;  4DR1 H;  4B8T A;  2OPU A;  4X62 H;  2LF0 A;  2JZX A;  5C0X G;  1XMO H;  1F0X A;  4DR3 H;  2PT7 G;  4JI1 H;  1Z2I A;  1VIH A;  3RF2 A;  4DV1 H;  4DR7 H;  4NZR M;  2UUB H;  2P2R A;  1HNX H;  4AQY H;  2HH3 A;  2UU9 H;  4LF5 H;  5BR8 H;  4K0K H;  2YQR A;  4YY3 H;  4KHP H;  2JE6 I;  5FLX W;  2CPQ A;  1ZTG A;  1N32 H;  2CPM A;  1N36 H;  1PQX A;  3GKU A;  2Z0S A;  2VQE H;  2G8Y A;  4E9J A;  1X4M A;  4JI5 H;  1I6U A;  1ZZJ A;  4YHH H;  2ZQE A;  2QND A;  4DUZ H;  4GKJ H;  3NCV A;  2CWH A;  2CWF A;  2E3U A;  3L7Z C;  4EC5 A;  4DV4 H;  2CTE A;  2E5L H;  5LL6 b;  2PY9 A;  1ZZI A;  4OO1 G;  1TUA A;  2CTJ A;  1FKA H;  2UUA H;  4PDB A;  5IT9 W;  4G08 A;  1AN7 A;  2FPH X; 
#chains in the Genus database with same CATH homology
 4H8A A;  1Z2I A;  2G8Y A;  3I0P A;  1WTJ A;  1X0A A;  4FJU A;  1NXU A;  1XRH A;  1V9N A;  3UOE A;  4FJS A;  1S20 A;  2CWH A;  1VBI A;  2X06 A;  2CWF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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