1X6AA

Solution structures of the second lim domain of human lim-kinase 2 (limk2)
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
81
structure length
81
Chain Sequence
GSSGSSGKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2)
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords LIM domain kinase 2
total genus 6
structure length 81
sequence length 81
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2005-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 1x6aA01
2D8YA 4KFZA 3MMKA 1V6GA 2DLOA 1U5SB 2EGQA 2YPAC 2CO8A 4HI9B 3F6QB 2LZUA 2EHEA 2MIUA 2CUPA 2IYBE 2O13A 2DARA 1IBIA 2CU8A 2L6ZC 2KBXB 2L4ZA 2XQNT 3IXEB 2O10A 1A7IA 1X61A 2MBVA 2DJ7A 2CUQA 1CXXA 2CORA 1J2OA 4HI8B 1X62A 1WYHA 2CURA 2JTNA 1IMLA 1RUTX 1X3HA 2XJZA 2D8ZA 2XJYA 2L6YB 1M3VA 1NYPA 1WIGA 2D8XA 1B8TA 2DFYC 1CTLA 1X68A 1G47A 2LXDA 1X6AA 1X4LA 1QLIA 1X64A 4JCJA 1X63A
chains in the Genus database with same CATH superfamily
5A1LA 1V6GA 4UF0A 2YPAC 5FP3A 3NINA 3AVRA 3NILA 2CUPA 5FXVA 2L4ZA 2O10A 2CUQA 1CXXA 4HI8B 2D8ZA 3ZPOA 1G47A 1B8TA 3ZLIA 1X68A 2LXDA 1X4LA 4JCJA 1X63A 3AVSA 5LKUA 3F6QB 2EHEA 2MIUA 2L6ZC 2XQNT 4UF0B 5FXZA 3NISA 4BHWA 2L6YB 1M3VA 1NYPA 1CTLA 1X6AA 5LKTA 5FY7A 2DLOA 2EGQA 5FXXA 2LZUA 4EYUA 2IYBE 2DARA 1IBIA 2CU8A 4ASKA 2DJ7A 5LKZA 1J2OA 1X62A 1WYHA 1RUTX 2XJYA 5FY0A 1WIGA 3NIKA 2DFYC 4EZHA 1QLIA 5FY1A 2D8YA 4KFZA 3MMKA 4EZ4A 1U5SB 2CO8A 4HI9B 3NIHA 2O13A 5LKXA 2KBXB 3NIMA 3IXEB 1A7IA 1X61A 2MBVA 2CORA 2CURA 2JTNA 1IMLA 1X3HA 2XJZA 2D8XA 3NIJA 2XUEA 5FYMA 1X64A 5FXWA
chains in the Genus database with same CATH topology
5A1LA 1V6GA 4UF0A 2YPAC 5FP3A 3NINA 3AVRA 3NILA 2CUPA 5FXVA 2L4ZA 2O10A 2CUQA 1CXXA 4HI8B 2D8ZA 3ZPOA 1G47A 1B8TA 3ZLIA 1X68A 2LXDA 1X4LA 4JCJA 1X63A 3AVSA 5LKUA 3F6QB 2EHEA 2MIUA 2L6ZC 2XQNT 4UF0B 5FXZA 3NISA 4BHWA 2L6YB 1M3VA 1NYPA 1CTLA 1X6AA 5LKTA 5FY7A 2DLOA 2EGQA 5FXXA 2LZUA 4EYUA 2IYBE 2DARA 1IBIA 2CU8A 4ASKA 2DJ7A 5LKZA 1J2OA 1X62A 1WYHA 1RUTX 2XJYA 5FY0A 1WIGA 3NIKA 2DFYC 4EZHA 1QLIA 5FY1A 2D8YA 4KFZA 3MMKA 4EZ4A 1U5SB 2CO8A 4HI9B 3NIHA 2O13A 5LKXA 2KBXB 3NIMA 3IXEB 1A7IA 1X61A 2MBVA 2CORA 2CURA 2JTNA 1IMLA 1X3HA 2XJZA 2D8XA 3NIJA 2XUEA 5FYMA 1X64A 5FXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D8Y A;  4KFZ A;  3MMK A;  1V6G A;  2DLO A;  1U5S B;  2EGQ A;  2YPA C;  2CO8 A;  4HI9 B;  3F6Q B;  2LZU A;  2EHE A;  2MIU A;  2CUP A;  2IYB E;  2O13 A;  2DAR A;  1IBI A;  2CU8 A;  2L6Z C;  2KBX B;  2L4Z A;  2XQN T;  3IXE B;  2O10 A;  1A7I A;  1X61 A;  2MBV A;  2DJ7 A;  2CUQ A;  1CXX A;  2COR A;  1J2O A;  4HI8 B;  1X62 A;  1WYH A;  2CUR A;  2JTN A;  1IML A;  1RUT X;  1X3H A;  2XJZ A;  2D8Z A;  2XJY A;  2L6Y B;  1M3V A;  1NYP A;  1WIG A;  2D8X A;  1B8T A;  2DFY C;  1CTL A;  1X68 A;  1G47 A;  2LXD A;  1X6A A;  1X4L A;  1QLI A;  1X64 A;  4JCJ A;  1X63 A; 
#chains in the Genus database with same CATH topology
 5A1L A;  1V6G A;  4UF0 A;  2YPA C;  5FP3 A;  3NIN A;  3AVR A;  3NIL A;  2CUP A;  5FXV A;  2L4Z A;  2O10 A;  2CUQ A;  1CXX A;  4HI8 B;  2D8Z A;  3ZPO A;  1G47 A;  1B8T A;  3ZLI A;  1X68 A;  2LXD A;  1X4L A;  4JCJ A;  1X63 A;  3AVS A;  5LKU A;  3F6Q B;  2EHE A;  2MIU A;  2L6Z C;  2XQN T;  4UF0 B;  5FXZ A;  3NIS A;  4BHW A;  2L6Y B;  1M3V A;  1NYP A;  1CTL A;  1X6A A;  5LKT A;  5FY7 A;  2DLO A;  2EGQ A;  5FXX A;  2LZU A;  4EYU A;  2IYB E;  2DAR A;  1IBI A;  2CU8 A;  4ASK A;  2DJ7 A;  5LKZ A;  1J2O A;  1X62 A;  1WYH A;  1RUT X;  2XJY A;  5FY0 A;  1WIG A;  3NIK A;  2DFY C;  4EZH A;  1QLI A;  5FY1 A;  2D8Y A;  4KFZ A;  3MMK A;  4EZ4 A;  1U5S B;  2CO8 A;  4HI9 B;  3NIH A;  2O13 A;  5LKX A;  2KBX B;  3NIM A;  3IXE B;  1A7I A;  1X61 A;  2MBV A;  2COR A;  2CUR A;  2JTN A;  1IML A;  1X3H A;  2XJZ A;  2D8X A;  3NIJ A;  2XUE A;  5FYM A;  1X64 A;  5FXW A; 
#chains in the Genus database with same CATH homology
 5A1L A;  1V6G A;  4UF0 A;  2YPA C;  5FP3 A;  3NIN A;  3AVR A;  3NIL A;  2CUP A;  5FXV A;  2L4Z A;  2O10 A;  2CUQ A;  1CXX A;  4HI8 B;  2D8Z A;  3ZPO A;  1G47 A;  1B8T A;  3ZLI A;  1X68 A;  2LXD A;  1X4L A;  4JCJ A;  1X63 A;  3AVS A;  5LKU A;  3F6Q B;  2EHE A;  2MIU A;  2L6Z C;  2XQN T;  4UF0 B;  5FXZ A;  3NIS A;  4BHW A;  2L6Y B;  1M3V A;  1NYP A;  1CTL A;  1X6A A;  5LKT A;  5FY7 A;  2DLO A;  2EGQ A;  5FXX A;  2LZU A;  4EYU A;  2IYB E;  2DAR A;  1IBI A;  2CU8 A;  4ASK A;  2DJ7 A;  5LKZ A;  1J2O A;  1X62 A;  1WYH A;  1RUT X;  2XJY A;  5FY0 A;  1WIG A;  3NIK A;  2DFY C;  4EZH A;  1QLI A;  5FY1 A;  2D8Y A;  4KFZ A;  3MMK A;  4EZ4 A;  1U5S B;  2CO8 A;  4HI9 B;  3NIH A;  2O13 A;  5LKX A;  2KBX B;  3NIM A;  3IXE B;  1A7I A;  1X61 A;  2MBV A;  2COR A;  2CUR A;  2JTN A;  1IML A;  1X3H A;  2XJZ A;  2D8X A;  3NIJ A;  2XUE A;  5FYM A;  1X64 A;  5FXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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