1XBOA

Ptp1b complexed with isoxazole carboxylic acid
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
298
structure length
298
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 103
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1xboA00
2CNHA 1OHDA 4R0SA 2C7SA 1YGRA 3I36A 4HJPA 2AHSA 3QCGA 2NTAA 1D5RA 1XRIA 5K23A 3EMUA 3MMJA 3S3FA 1MKPA 1QZ0A 3AWGA 5IBSA 1NWEA 2I6MA 2NV5A 1PH0A 1ZC0A 4OHEA 4WTYA 3RGOA 1YZ4A 1T48A 1G1FA 2NT7A 3LJ8A 4RHGA 4J51A 2PT0A 3MOWA 1ECVA 1G1HA 2DXPA 1NZ7A 1LYVA 3BRHA 4OHIA 1U24A 3O3LA 1OEMX 2F6TA 1NL9A 3CM3A 3OLRA 5EHPA 1G4WR 3ZMQA 1L8KA 2M3VA 4R30A 5BX1A 2E0TA 2Q47A 4NNDA 4GS0A 1WAXA 1R6HA 2CMBA 4OHDA 5M43A 3N0AA 2BZLA 2I1YA 2B07A 1NO6A 1Q6TA 5KA1A 1I9TA 4JNBA 2J17A 1BZJA 1GWZA 1OHCA 2PBNA 2OUDA 4WU3A 2F70A 2B4OA 2AZRA 1WRMA 1T4JA 3D1OA 1GFYA 2VEVA 2FJMA 4GE2A 2YDUA 2WGPA 2B4SA 4NX8A 4BPCA 1PTVA 2PA5A 2QCJA 3ZMPA 3QCNA 3D9CA 2F6WA 3QCKA 4BJOA 5KA0A 1XXPA 4GE6A 2R0BA 1WCHA 1Q6SA 2VEYA 3BLTA 3QCIA 1YTWA 2QBQA 4WU2A 5GTJA 2VEXA 3AWEA 1U26A 4PYHA 2NT2A 2CNFA 3F81A 2VEUA 4S0GA 1OETA 4TVVA 1L8GA 2BIJA 1Q6NA 1PTYA 4JMJA 3QCCA 2I6IA 4GE5A 1FPZA 4MBBA 4QAHA 2G6ZA 2F46A 4D3PA 3D1HA 2HVLA 3BM8A 2IMGA 4H34A 4ICZA 4IKCA 2I6OA 3EU0A 5AWXA 2HCMA 2H4VA 5IBMA 2H04A 4H1OA 3CWEA 2HNQA 5K9WA 2PQ5A 2F6ZA 1I57A 1P15A 3S4OA 3O4UA 3S3EA 5KA7A 5BZZA 2F6FA 5KA3A 4WOHA 3H2XA 1M3GA 4RH5A 2J16B 1G7FA 3D44A 4QAPA 2GJTA 3ZM0A 2H03A 2GP0A 1EENA 2F6VA 2FJNA 3ZM3A 3V0DA 1PA1A 4JBCA 5BUGA 1SUGA 2PI7A 4QBEA 2H02A 2ZMMA 3S4EA 4GRZA 4YAAA 2MBCA 5KAAA 4DGXA 1U25A 2HY3A 5MMZB 4ZRTA 2CFVA 1Q6MA 2CM2A 1OEUA 2BGDA 2C46A 3RZ2A 4GFVA 2F6YA 1Q6JA 3QCLA 4Y2EA 1ZZWA 3B7OA 2I5XA 4HRFA 1T49A 3BLUA 4QBWA 1PTTA 3EZZA 1EEOA 3F9BA 1YFOA 1NNYA 1AAXA 2CM8A 2OOQA 2HB1A 4RKKA 2QBSA 2CM7A 2VEWA 1PYNA 1ZCLA 5HDEA 1V3AA 5EHRA 1G7GA 2HNPA 2Y96A 3GXHA 5KA9A 3QKQA 2I4HA 2I6PA 4NYHA 3QCMA 5K22A 3F99A 3GXGA 2ZN7A 2CMAA 4QUMA 2FH7A 1X24A 4JMKA 3A5JA 5KA2A 1PXHA 1A5YA 2I4GA 5I6VA 2QDPA 2NLKA 3U96A 2QDMA 2G59A 2Q05A 2CMCA 3V0FA 1OEOX 3F41A 2BV5A 4D3QA 2QBPA 4HJQA 1I9SA 2CM3A 1C88A 3V0GA 3S3KA 2I42A 4OHLA 4ZI4A 2I6JA 3ZM1A 1VHRA 2J16A 2Y2FA 1YWFA 5LXQB 1G4US 1YN9A 4KYRA 1BZCA 4KYQA 1RXDA 2CJZA 1FPRA 2I3RA 2CNGA 3V0HA 4RI4A 1J4XA 1C84A 2QCTA 2F71A 2ESBA 3ZM2A 1BZHA 1LQFA 4PVGA 4GRYA 1G1GA 2CNEA 4Z6BA 1Q6PA 3O5XA 2P6XA 1OEVA 4OHHA 3AWFA 2GWOA 4GFUA 4ERCA 2B4PA 2B49A 2I3UA 2RF6A 5K25A 1QXKA 5K24A 3NMEA 3QCDA 1OHEA 3MOZA 1PTUA 5BZXA 2PSZA 2QDCA 3QCEA 1YTSA 3QCFA 3OMHA 3D42A 5K9VA 2HC1A 3I7ZA 1XM2A 4Y14A 3D1QA 3RO1A 3V0IA 4DGPA 3EAXA 3M4UA 1JF7A 2P4DA 4GWFA 2H4GA 3QKPA 4I8NA 1C83A 3V0JA 3EB1A 1FQ1A 1PA9A 3A5KA 5KA4A 3S3HA 1C87A 2A8BA 3O4TA 2CNIA 2HC2A 2A3KA 2I4EA 4B04A 1YPTA 2QBRA 4YR8B 4KI9A 4NWFA 1LARA 3RGQA 1OESA 2QEPA 1ZCKA 2I75A 1Q1MA 2HXPA 3QCBA 2B4UA 4D3RA 2NZ6A 1JLNA 1XXVA 3SR9A 1NWLA 2SHPA 5KADA 1ONYA 3V0EA 1KAVA 2H4KA 4R0TA 1XBOA 4RH9A 1YTNA 2OC3A 1YGUA 2OZ5A 5KABA 1KAKA 1C85A 2JJDA 5KA8A 3O4SA 4RDDA 3ZV2A 5J8RA 4RI5A 1RPMA 3QCJA 4AZ1A 3I80A 2BGEA 3SMEA 4NWGA 5KACA 3F9AA 1C86A 3QCHA 3PS5A 1ONZA 2B3OA 4QUNA 4ZN5A
chains in the Genus database with same CATH superfamily
2CNHA 1OHDA 4R0SA 2C7SA 1YGRA 3I36A 1O5ZA 4HJPA 2AHSA 3QCGA 2NTAA 1D5RA 1XRIA 1EEHA 5K23A 3EMUA 3MMJA 3S3FA 1MKPA 1QZ0A 3AWGA 5IBSA 1NWEA 2I6MA 1E0DA 2NV5A 2Y67A 1PH0A 1ZC0A 4OHEA 2AM1A 4WTYA 3RGOA 1YZ4A 1T48A 1G1FA 2NT7A 3LJ8A 4RHGA 4J51A 2PT0A 3MOWA 1ECVA 1G1HA 2DXPA 1NZ7A 1LYVA 4C12A 4CVKA 3BRHA 4OHIA 1E8CA 1U24A 3O3LA 4QF5A 1OEMX 2F6TA 1NL9A 3CM3A 3OLRA 5EHPA 1G4WR 3ZMQA 1L8KA 2M3VA 4R30A 5BX1A 2E0TA 2Q47A 4NNDA 2JFFA 4GS0A 1WAXA 1R6HA 2CMBA 4OHDA 5M43A 3N0AA 2BZLA 2I1YA 2B07A 1NO6A 1Q6TA 5KA1A 1I9TA 4JNBA 2J17A 1BZJA 1GWZA 1OHCA 2PBNA 2OUDA 3QCZA 2GC5A 2F70A 4WU3A 2B4OA 2AZRA 1WRMA 1T4JA 3D1OA 1GFYA 2VEVA 2FJMA 4GE2A 1GQYA 2YDUA 2WGPA 2B4SA 4NX8A 4BPCA 1PTVA 2PA5A 2QCJA 3ZMPA 3QCNA 2VORA 3D9CA 2F6WA 3QCKA 4BJOA 5KA0A 1XXPA 4GE6A 2R0BA 1WCHA 1Q6SA 2VEYA 3BLTA 3QCIA 1P31A 1YTWA 2QBQA 4WU2A 5GTJA 2VEXA 3AWEA 1U26A 4CVLA 4PYHA 2NT2A 2CNFA 3F81A 2JFGA 2VEUA 4S0GA 1OETA 4TVVA 1L8GA 2BIJA 1Q6NA 3UAGA 1PTYA 4JMJA 3QCCA 2I6IA 4GE5A 1FPZA 4MBBA 4QAHA 2G6ZA 2F46A 4D3PA 3D1HA 2HVLA 3BM8A 1JBWA 2IMGA 4H34A 4ICZA 4IKCA 4ZIYA 2I6OA 3EU0A 5AWXA 2HCMA 2H4VA 5IBMA 2H04A 4H1OA 3CWEA 2HNQA 5K9WA 2PQ5A 2F6ZA 1I57A 1P15A 3S4OA 3O4UA 3S3EA 5KA7A 5BZZA 2F6FA 5KA3A 4WOHA 3H2XA 1M3GA 4RH5A 2J16B 3ZL8A 1G7FA 2VOSA 3D44A 4QAPA 2GJTA 2Y1OA 3ZM0A 2H03A 2GP0A 2AM2A 1EENA 2F6VA 2FJNA 3ZM3A 3V0DA 1PA1A 3HN7A 4JBCA 5BUGA 1SUGA 2PI7A 4QBEA 2H02A 2ZMMA 3S4EA 4GRZA 4YAAA 2MBCA 5KAAA 4DGXA 1U25A 2HY3A 1GQQA 5MMZB 4ZRTA 2CFVA 1Q6MA 2CM2A 3MVNA 1OEUA 2BGDA 4BUBA 2C46A 3RZ2A 4GFVA 2F6YA 1Q6JA 3QCLA 4Y2EA 1ZZWA 3B7OA 2I5XA 4HRFA 1T49A 3BLUA 4QBWA 1PTTA 3EZZA 1EEOA 3F9BA 1YFOA 1NNYA 1AAXA 2Y66A 2CM8A 2OOQA 1W7KA 2HB1A 4RKKA 2QBSA 2CM7A 2VEWA 1PYNA 1ZCLA 5HDEA 1V3AA 2GCBA 5EHRA 1G7GA 2HNPA 2WTZA 1UAGA 2Y96A 3GXHA 5A5EA 5KA9A 3QKQA 2I4HA 2I6PA 2Y68A 4NYHA 3QCMA 3N2AA 5K22A 3F99A 3GXGA 2ZN7A 2CMAA 4QUMA 2F00A 2FH7A 1X24A 4JMKA 3A5JA 5KA2A 1PXHA 1A5YA 2I4GA 5I6VA 2QDPA 2NLKA 3U96A 2QDMA 2G59A 2Q05A 2UAGA 2CMCA 3V0FA 3NRSA 1OEOX 3F41A 2BV5A 4D3QA 2QBPA 4HJQA 1I9SA 2CM3A 1C88A 2WJPA 3V0GA 3S3KA 2I42A 4OHLA 1JBVA 4ZI4A 2I6JA 1J6UA 3ZM1A 1VHRA 2J16A 2Y2FA 4C13A 1YWFA 5LXQB 1G4US 2JFHA 1YN9A 4KYRA 1BZCA 4KYQA 2GC6A 1RXDA 2CJZA 1FPRA 2I3RA 2CNGA 3V0HA 4RI4A 1J4XA 3ZM5A 1C84A 2QCTA 2F71A 1GG4A 2ESBA 4QDIA 2XJAA 3ZM2A 1BZHA 1LQFA 4PVGA 4GRYA 1G1GA 2CNEA 4Z6BA 1Q6PA 3LK7A 3O5XA 2P6XA 2GCAA 1OEVA 4OHHA 3AWFA 2GWOA 4GFUA 4ERCA 2B4PA 2B49A 2I3UA 2RF6A 2XPCA 5K25A 1QXKA 5K24A 3NMEA 3QCDA 4UAGA 1OHEA 1P3DA 3MOZA 1PTUA 5BZXA 2PSZA 2QDCA 3QCEA 2X5OA 1YTSA 3QCFA 3OMHA 3D42A 5K9VA 2HC1A 3I7ZA 1XM2A 4Y14A 3D1QA 3RO1A 3V0IA 4DGPA 1W78A 3EAXA 3M4UA 1JF7A 2P4DA 4GWFA 2H4GA 2UUPA 3QKPA 4I8NA 1C83A 3V0JA 3EB1A 1FQ1A 1PA9A 3A5KA 5KA4A 2VTEA 3S3HA 1C87A 2A8BA 3O4TA 2CNIA 2HC2A 2A3KA 2I4EA 4B04A 1YPTA 2QBRA 4CVMA 4YR8B 2VTDA 4KI9A 4NWFA 1LARA 3RGQA 1OESA 1FGSA 2QEPA 1ZCKA 2I75A 1Q1MA 2HXPA 3QCBA 2B4UA 4D3RA 2NZ6A 1JLNA 1XXVA 3SR9A 1NWLA 2SHPA 4BUCA 5KADA 1ONYA 3V0EA 1KAVA 2H4KA 4R0TA 1XBOA 4RH9A 1YTNA 2OC3A 1YGUA 2OZ5A 5KABA 1KAKA 4HV4A 1C85A 2JJDA 5KA8A 3O4SA 4RDDA 3ZV2A 5J8RA 4RI5A 1RPMA 3QCJA 3PYZA 4AZ1A 3I80A 2BGEA 3SMEA 4NWGA 5KACA 3F9AA 1C86A 3QCHA 5A5FA 3PS5A 1ONZA 3ZM6A 2B3OA 4QUNA 4ZN5A 2UUOA
chains in the Genus database with same CATH topology
2CNHA 1OHDA 4R0SA 2C7SA 1YGRA 3I36A 4HJPA 2AHSA 3QCGA 2NTAA 1D5RA 1XRIA 5K23A 3EMUA 3MMJA 3S3FA 1MKPA 1QZ0A 3AWGA 5IBSA 1NWEA 2I6MA 2NV5A 1PH0A 1ZC0A 4OHEA 4WTYA 3RGOA 1YZ4A 1T48A 1G1FA 2NT7A 3LJ8A 4RHGA 4J51A 2PT0A 3MOWA 1ECVA 1G1HA 2DXPA 1NZ7A 1LYVA 3BRHA 4OHIA 1U24A 3O3LA 1OEMX 2F6TA 1NL9A 3CM3A 3OLRA 5EHPA 1G4WR 3ZMQA 1L8KA 2M3VA 4R30A 5BX1A 2E0TA 2Q47A 4NNDA 4GS0A 1WAXA 1R6HA 2CMBA 4OHDA 5M43A 3N0AA 2BZLA 2I1YA 2B07A 1NO6A 1Q6TA 5KA1A 1I9TA 4JNBA 2J17A 1BZJA 1GWZA 1OHCA 2PBNA 2OUDA 4WU3A 2F70A 2B4OA 2AZRA 1WRMA 1T4JA 3D1OA 1GFYA 2VEVA 2FJMA 4GE2A 2YDUA 2WGPA 2B4SA 4NX8A 4BPCA 1PTVA 2PA5A 2QCJA 3ZMPA 3QCNA 3D9CA 2F6WA 3QCKA 4BJOA 5KA0A 1XXPA 4GE6A 2R0BA 1WCHA 1Q6SA 2VEYA 3BLTA 3QCIA 1YTWA 2QBQA 4WU2A 5GTJA 2VEXA 3AWEA 1U26A 4PYHA 2NT2A 2CNFA 3F81A 2VEUA 4S0GA 1OETA 4TVVA 1L8GA 2BIJA 1Q6NA 1PTYA 4JMJA 3QCCA 2I6IA 4GE5A 1FPZA 4MBBA 4QAHA 2G6ZA 2F46A 4D3PA 3D1HA 2HVLA 3BM8A 2IMGA 4H34A 4ICZA 4IKCA 2I6OA 3EU0A 5AWXA 2HCMA 2H4VA 5IBMA 2H04A 4H1OA 3CWEA 2HNQA 5K9WA 2PQ5A 2F6ZA 1I57A 1P15A 3S4OA 3O4UA 3S3EA 5KA7A 5BZZA 2F6FA 5KA3A 4WOHA 3H2XA 1M3GA 4RH5A 2J16B 1G7FA 3D44A 4QAPA 2GJTA 3ZM0A 2H03A 2GP0A 1EENA 2F6VA 2FJNA 3ZM3A 3V0DA 1PA1A 4JBCA 5BUGA 1SUGA 2PI7A 4QBEA 2H02A 2ZMMA 3S4EA 4GRZA 4YAAA 2MBCA 5KAAA 4DGXA 1U25A 2HY3A 5MMZB 4ZRTA 2CFVA 1Q6MA 2CM2A 1OEUA 2BGDA 2C46A 3RZ2A 4GFVA 2F6YA 1Q6JA 3QCLA 4Y2EA 1ZZWA 3B7OA 2I5XA 4HRFA 1T49A 3BLUA 4QBWA 1PTTA 3EZZA 1EEOA 3F9BA 1YFOA 1NNYA 1AAXA 2CM8A 2OOQA 2HB1A 4RKKA 2QBSA 2CM7A 2VEWA 1PYNA 1ZCLA 5HDEA 1V3AA 5EHRA 1G7GA 2HNPA 2Y96A 3GXHA 5KA9A 3QKQA 2I4HA 2I6PA 4NYHA 3QCMA 5K22A 3F99A 3GXGA 2ZN7A 2CMAA 4QUMA 2FH7A 1X24A 4JMKA 3A5JA 5KA2A 1PXHA 1A5YA 2I4GA 5I6VA 2QDPA 2NLKA 3U96A 2QDMA 2G59A 2Q05A 2CMCA 3V0FA 1OEOX 3F41A 2BV5A 4D3QA 2QBPA 4HJQA 1I9SA 2CM3A 1C88A 3V0GA 3S3KA 2I42A 4OHLA 4ZI4A 2I6JA 3ZM1A 1VHRA 2J16A 2Y2FA 1YWFA 5LXQB 1G4US 1YN9A 4KYRA 1BZCA 4KYQA 1RXDA 2CJZA 1FPRA 2I3RA 2CNGA 3V0HA 4RI4A 1J4XA 1C84A 2QCTA 2F71A 2ESBA 3ZM2A 1BZHA 1LQFA 4PVGA 4GRYA 1G1GA 2CNEA 4Z6BA 1Q6PA 3O5XA 2P6XA 1OEVA 4OHHA 3AWFA 2GWOA 4GFUA 4ERCA 2B4PA 2B49A 2I3UA 2RF6A 5K25A 1QXKA 5K24A 3NMEA 3QCDA 1OHEA 3MOZA 1PTUA 5BZXA 2PSZA 2QDCA 3QCEA 1YTSA 3QCFA 3OMHA 3D42A 5K9VA 2HC1A 3I7ZA 1XM2A 4Y14A 3D1QA 3RO1A 3V0IA 4DGPA 3EAXA 3M4UA 1JF7A 2P4DA 4GWFA 2H4GA 3QKPA 4I8NA 1C83A 3V0JA 3EB1A 1FQ1A 1PA9A 3A5KA 5KA4A 3S3HA 1C87A 2A8BA 3O4TA 2CNIA 2HC2A 2A3KA 2I4EA 4B04A 1YPTA 2QBRA 4YR8B 4KI9A 4NWFA 1LARA 3RGQA 1OESA 2QEPA 1ZCKA 2I75A 1Q1MA 2HXPA 3QCBA 2B4UA 4D3RA 2NZ6A 1JLNA 1XXVA 3SR9A 1NWLA 2SHPA 5KADA 1ONYA 3V0EA 1KAVA 2H4KA 4R0TA 1XBOA 4RH9A 1YTNA 2OC3A 1YGUA 2OZ5A 5KABA 1KAKA 1C85A 2JJDA 5KA8A 3O4SA 4RDDA 3ZV2A 5J8RA 4RI5A 1RPMA 3QCJA 4AZ1A 3I80A 2BGEA 3SMEA 4NWGA 5KACA 3F9AA 1C86A 3QCHA 3PS5A 1ONZA 2B3OA 4QUNA 4ZN5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CNH A;  1OHD A;  4R0S A;  2C7S A;  1YGR A;  3I36 A;  4HJP A;  2AHS A;  3QCG A;  2NTA A;  1D5R A;  1XRI A;  5K23 A;  3EMU A;  3MMJ A;  3S3F A;  1MKP A;  1QZ0 A;  3AWG A;  5IBS A;  1NWE A;  2I6M A;  2NV5 A;  1PH0 A;  1ZC0 A;  4OHE A;  4WTY A;  3RGO A;  1YZ4 A;  1T48 A;  1G1F A;  2NT7 A;  3LJ8 A;  4RHG A;  4J51 A;  2PT0 A;  3MOW A;  1ECV A;  1G1H A;  2DXP A;  1NZ7 A;  1LYV A;  3BRH A;  4OHI A;  1U24 A;  3O3L A;  1OEM X;  2F6T A;  1NL9 A;  3CM3 A;  3OLR A;  5EHP A;  1G4W R;  3ZMQ A;  1L8K A;  2M3V A;  4R30 A;  5BX1 A;  2E0T A;  2Q47 A;  4NND A;  4GS0 A;  1WAX A;  1R6H A;  2CMB A;  4OHD A;  5M43 A;  3N0A A;  2BZL A;  2I1Y A;  2B07 A;  1NO6 A;  1Q6T A;  5KA1 A;  1I9T A;  4JNB A;  2J17 A;  1BZJ A;  1GWZ A;  1OHC A;  2PBN A;  2OUD A;  4WU3 A;  2F70 A;  2B4O A;  2AZR A;  1WRM A;  1T4J A;  3D1O A;  1GFY A;  2VEV A;  2FJM A;  4GE2 A;  2YDU A;  2WGP A;  2B4S A;  4NX8 A;  4BPC A;  1PTV A;  2PA5 A;  2QCJ A;  3ZMP A;  3QCN A;  3D9C A;  2F6W A;  3QCK A;  4BJO A;  5KA0 A;  1XXP A;  4GE6 A;  2R0B A;  1WCH A;  1Q6S A;  2VEY A;  3BLT A;  3QCI A;  1YTW A;  2QBQ A;  4WU2 A;  5GTJ A;  2VEX A;  3AWE A;  1U26 A;  4PYH A;  2NT2 A;  2CNF A;  3F81 A;  2VEU A;  4S0G A;  1OET A;  4TVV A;  1L8G A;  2BIJ A;  1Q6N A;  1PTY A;  4JMJ A;  3QCC A;  2I6I A;  4GE5 A;  1FPZ A;  4MBB A;  4QAH A;  2G6Z A;  2F46 A;  4D3P A;  3D1H A;  2HVL A;  3BM8 A;  2IMG A;  4H34 A;  4ICZ A;  4IKC A;  2I6O A;  3EU0 A;  5AWX A;  2HCM A;  2H4V A;  5IBM A;  2H04 A;  4H1O A;  3CWE A;  2HNQ A;  5K9W A;  2PQ5 A;  2F6Z A;  1I57 A;  1P15 A;  3S4O A;  3O4U A;  3S3E A;  5KA7 A;  5BZZ A;  2F6F A;  5KA3 A;  4WOH A;  3H2X A;  1M3G A;  4RH5 A;  2J16 B;  1G7F A;  3D44 A;  4QAP A;  2GJT A;  3ZM0 A;  2H03 A;  2GP0 A;  1EEN A;  2F6V A;  2FJN A;  3ZM3 A;  3V0D A;  1PA1 A;  4JBC A;  5BUG A;  1SUG A;  2PI7 A;  4QBE A;  2H02 A;  2ZMM A;  3S4E A;  4GRZ A;  4YAA A;  2MBC A;  5KAA A;  4DGX A;  1U25 A;  2HY3 A;  5MMZ B;  4ZRT A;  2CFV A;  1Q6M A;  2CM2 A;  1OEU A;  2BGD A;  2C46 A;  3RZ2 A;  4GFV A;  2F6Y A;  1Q6J A;  3QCL A;  4Y2E A;  1ZZW A;  3B7O A;  2I5X A;  4HRF A;  1T49 A;  3BLU A;  4QBW A;  1PTT A;  3EZZ A;  1EEO A;  3F9B A;  1YFO A;  1NNY A;  1AAX A;  2CM8 A;  2OOQ A;  2HB1 A;  4RKK A;  2QBS A;  2CM7 A;  2VEW A;  1PYN A;  1ZCL A;  5HDE A;  1V3A A;  5EHR A;  1G7G A;  2HNP A;  2Y96 A;  3GXH A;  5KA9 A;  3QKQ A;  2I4H A;  2I6P A;  4NYH A;  3QCM A;  5K22 A;  3F99 A;  3GXG A;  2ZN7 A;  2CMA A;  4QUM A;  2FH7 A;  1X24 A;  4JMK A;  3A5J A;  5KA2 A;  1PXH A;  1A5Y A;  2I4G A;  5I6V A;  2QDP A;  2NLK A;  3U96 A;  2QDM A;  2G59 A;  2Q05 A;  2CMC A;  3V0F A;  1OEO X;  3F41 A;  2BV5 A;  4D3Q A;  2QBP A;  4HJQ A;  1I9S A;  2CM3 A;  1C88 A;  3V0G A;  3S3K A;  2I42 A;  4OHL A;  4ZI4 A;  2I6J A;  3ZM1 A;  1VHR A;  2J16 A;  2Y2F A;  1YWF A;  5LXQ B;  1G4U S;  1YN9 A;  4KYR A;  1BZC A;  4KYQ A;  1RXD A;  2CJZ A;  1FPR A;  2I3R A;  2CNG A;  3V0H A;  4RI4 A;  1J4X A;  1C84 A;  2QCT A;  2F71 A;  2ESB A;  3ZM2 A;  1BZH A;  1LQF A;  4PVG A;  4GRY A;  1G1G A;  2CNE A;  4Z6B A;  1Q6P A;  3O5X A;  2P6X A;  1OEV A;  4OHH A;  3AWF A;  2GWO A;  4GFU A;  4ERC A;  2B4P A;  2B49 A;  2I3U A;  2RF6 A;  5K25 A;  1QXK A;  5K24 A;  3NME A;  3QCD A;  1OHE A;  3MOZ A;  1PTU A;  5BZX A;  2PSZ A;  2QDC A;  3QCE A;  1YTS A;  3QCF A;  3OMH A;  3D42 A;  5K9V A;  2HC1 A;  3I7Z A;  1XM2 A;  4Y14 A;  3D1Q A;  3RO1 A;  3V0I A;  4DGP A;  3EAX A;  3M4U A;  1JF7 A;  2P4D A;  4GWF A;  2H4G A;  3QKP A;  4I8N A;  1C83 A;  3V0J A;  3EB1 A;  1FQ1 A;  1PA9 A;  3A5K A;  5KA4 A;  3S3H A;  1C87 A;  2A8B A;  3O4T A;  2CNI A;  2HC2 A;  2A3K A;  2I4E A;  4B04 A;  1YPT A;  2QBR A;  4YR8 B;  4KI9 A;  4NWF A;  1LAR A;  3RGQ A;  1OES A;  2QEP A;  1ZCK A;  2I75 A;  1Q1M A;  2HXP A;  3QCB A;  2B4U A;  4D3R A;  2NZ6 A;  1JLN A;  1XXV A;  3SR9 A;  1NWL A;  2SHP A;  5KAD A;  1ONY A;  3V0E A;  1KAV A;  2H4K A;  4R0T A;  1XBO A;  4RH9 A;  1YTN A;  2OC3 A;  1YGU A;  2OZ5 A;  5KAB A;  1KAK A;  1C85 A;  2JJD A;  5KA8 A;  3O4S A;  4RDD A;  3ZV2 A;  5J8R A;  4RI5 A;  1RPM A;  3QCJ A;  4AZ1 A;  3I80 A;  2BGE A;  3SME A;  4NWG A;  5KAC A;  3F9A A;  1C86 A;  3QCH A;  3PS5 A;  1ONZ A;  2B3O A;  4QUN A;  4ZN5 A; 
#chains in the Genus database with same CATH topology
 2CNH A;  1OHD A;  4R0S A;  2C7S A;  1YGR A;  3I36 A;  1O5Z A;  4HJP A;  2AHS A;  3QCG A;  2NTA A;  1D5R A;  1XRI A;  1EEH A;  5K23 A;  3EMU A;  3MMJ A;  3S3F A;  1MKP A;  1QZ0 A;  3AWG A;  5IBS A;  1NWE A;  2I6M A;  1E0D A;  2NV5 A;  2Y67 A;  1PH0 A;  1ZC0 A;  4OHE A;  2AM1 A;  4WTY A;  3RGO A;  1YZ4 A;  1T48 A;  1G1F A;  2NT7 A;  3LJ8 A;  4RHG A;  4J51 A;  2PT0 A;  3MOW A;  1ECV A;  1G1H A;  2DXP A;  1NZ7 A;  1LYV A;  4C12 A;  4CVK A;  3BRH A;  4OHI A;  1E8C A;  1U24 A;  3O3L A;  4QF5 A;  1OEM X;  2F6T A;  1NL9 A;  3CM3 A;  3OLR A;  5EHP A;  1G4W R;  3ZMQ A;  1L8K A;  2M3V A;  4R30 A;  5BX1 A;  2E0T A;  2Q47 A;  4NND A;  2JFF A;  4GS0 A;  1WAX A;  1R6H A;  2CMB A;  4OHD A;  5M43 A;  3N0A A;  2BZL A;  2I1Y A;  2B07 A;  1NO6 A;  1Q6T A;  5KA1 A;  1I9T A;  4JNB A;  2J17 A;  1BZJ A;  1GWZ A;  1OHC A;  2PBN A;  2OUD A;  3QCZ A;  2GC5 A;  2F70 A;  4WU3 A;  2B4O A;  2AZR A;  1WRM A;  1T4J A;  3D1O A;  1GFY A;  2VEV A;  2FJM A;  4GE2 A;  1GQY A;  2YDU A;  2WGP A;  2B4S A;  4NX8 A;  4BPC A;  1PTV A;  2PA5 A;  2QCJ A;  3ZMP A;  3QCN A;  2VOR A;  3D9C A;  2F6W A;  3QCK A;  4BJO A;  5KA0 A;  1XXP A;  4GE6 A;  2R0B A;  1WCH A;  1Q6S A;  2VEY A;  3BLT A;  3QCI A;  1P31 A;  1YTW A;  2QBQ A;  4WU2 A;  5GTJ A;  2VEX A;  3AWE A;  1U26 A;  4CVL A;  4PYH A;  2NT2 A;  2CNF A;  3F81 A;  2JFG A;  2VEU A;  4S0G A;  1OET A;  4TVV A;  1L8G A;  2BIJ A;  1Q6N A;  3UAG A;  1PTY A;  4JMJ A;  3QCC A;  2I6I A;  4GE5 A;  1FPZ A;  4MBB A;  4QAH A;  2G6Z A;  2F46 A;  4D3P A;  3D1H A;  2HVL A;  3BM8 A;  1JBW A;  2IMG A;  4H34 A;  4ICZ A;  4IKC A;  4ZIY A;  2I6O A;  3EU0 A;  5AWX A;  2HCM A;  2H4V A;  5IBM A;  2H04 A;  4H1O A;  3CWE A;  2HNQ A;  5K9W A;  2PQ5 A;  2F6Z A;  1I57 A;  1P15 A;  3S4O A;  3O4U A;  3S3E A;  5KA7 A;  5BZZ A;  2F6F A;  5KA3 A;  4WOH A;  3H2X A;  1M3G A;  4RH5 A;  2J16 B;  3ZL8 A;  1G7F A;  2VOS A;  3D44 A;  4QAP A;  2GJT A;  2Y1O A;  3ZM0 A;  2H03 A;  2GP0 A;  2AM2 A;  1EEN A;  2F6V A;  2FJN A;  3ZM3 A;  3V0D A;  1PA1 A;  3HN7 A;  4JBC A;  5BUG A;  1SUG A;  2PI7 A;  4QBE A;  2H02 A;  2ZMM A;  3S4E A;  4GRZ A;  4YAA A;  2MBC A;  5KAA A;  4DGX A;  1U25 A;  2HY3 A;  1GQQ A;  5MMZ B;  4ZRT A;  2CFV A;  1Q6M A;  2CM2 A;  3MVN A;  1OEU A;  2BGD A;  4BUB A;  2C46 A;  3RZ2 A;  4GFV A;  2F6Y A;  1Q6J A;  3QCL A;  4Y2E A;  1ZZW A;  3B7O A;  2I5X A;  4HRF A;  1T49 A;  3BLU A;  4QBW A;  1PTT A;  3EZZ A;  1EEO A;  3F9B A;  1YFO A;  1NNY A;  1AAX A;  2Y66 A;  2CM8 A;  2OOQ A;  1W7K A;  2HB1 A;  4RKK A;  2QBS A;  2CM7 A;  2VEW A;  1PYN A;  1ZCL A;  5HDE A;  1V3A A;  2GCB A;  5EHR A;  1G7G A;  2HNP A;  2WTZ A;  1UAG A;  2Y96 A;  3GXH A;  5A5E A;  5KA9 A;  3QKQ A;  2I4H A;  2I6P A;  2Y68 A;  4NYH A;  3QCM A;  3N2A A;  5K22 A;  3F99 A;  3GXG A;  2ZN7 A;  2CMA A;  4QUM A;  2F00 A;  2FH7 A;  1X24 A;  4JMK A;  3A5J A;  5KA2 A;  1PXH A;  1A5Y A;  2I4G A;  5I6V A;  2QDP A;  2NLK A;  3U96 A;  2QDM A;  2G59 A;  2Q05 A;  2UAG A;  2CMC A;  3V0F A;  3NRS A;  1OEO X;  3F41 A;  2BV5 A;  4D3Q A;  2QBP A;  4HJQ A;  1I9S A;  2CM3 A;  1C88 A;  2WJP A;  3V0G A;  3S3K A;  2I42 A;  4OHL A;  1JBV A;  4ZI4 A;  2I6J A;  1J6U A;  3ZM1 A;  1VHR A;  2J16 A;  2Y2F A;  4C13 A;  1YWF A;  5LXQ B;  1G4U S;  2JFH A;  1YN9 A;  4KYR A;  1BZC A;  4KYQ A;  2GC6 A;  1RXD A;  2CJZ A;  1FPR A;  2I3R A;  2CNG A;  3V0H A;  4RI4 A;  1J4X A;  3ZM5 A;  1C84 A;  2QCT A;  2F71 A;  1GG4 A;  2ESB A;  4QDI A;  2XJA A;  3ZM2 A;  1BZH A;  1LQF A;  4PVG A;  4GRY A;  1G1G A;  2CNE A;  4Z6B A;  1Q6P A;  3LK7 A;  3O5X A;  2P6X A;  2GCA A;  1OEV A;  4OHH A;  3AWF A;  2GWO A;  4GFU A;  4ERC A;  2B4P A;  2B49 A;  2I3U A;  2RF6 A;  2XPC A;  5K25 A;  1QXK A;  5K24 A;  3NME A;  3QCD A;  4UAG A;  1OHE A;  1P3D A;  3MOZ A;  1PTU A;  5BZX A;  2PSZ A;  2QDC A;  3QCE A;  2X5O A;  1YTS A;  3QCF A;  3OMH A;  3D42 A;  5K9V A;  2HC1 A;  3I7Z A;  1XM2 A;  4Y14 A;  3D1Q A;  3RO1 A;  3V0I A;  4DGP A;  1W78 A;  3EAX A;  3M4U A;  1JF7 A;  2P4D A;  4GWF A;  2H4G A;  2UUP A;  3QKP A;  4I8N A;  1C83 A;  3V0J A;  3EB1 A;  1FQ1 A;  1PA9 A;  3A5K A;  5KA4 A;  2VTE A;  3S3H A;  1C87 A;  2A8B A;  3O4T A;  2CNI A;  2HC2 A;  2A3K A;  2I4E A;  4B04 A;  1YPT A;  2QBR A;  4CVM A;  4YR8 B;  2VTD A;  4KI9 A;  4NWF A;  1LAR A;  3RGQ A;  1OES A;  1FGS A;  2QEP A;  1ZCK A;  2I75 A;  1Q1M A;  2HXP A;  3QCB A;  2B4U A;  4D3R A;  2NZ6 A;  1JLN A;  1XXV A;  3SR9 A;  1NWL A;  2SHP A;  4BUC A;  5KAD A;  1ONY A;  3V0E A;  1KAV A;  2H4K A;  4R0T A;  1XBO A;  4RH9 A;  1YTN A;  2OC3 A;  1YGU A;  2OZ5 A;  5KAB A;  1KAK A;  4HV4 A;  1C85 A;  2JJD A;  5KA8 A;  3O4S A;  4RDD A;  3ZV2 A;  5J8R A;  4RI5 A;  1RPM A;  3QCJ A;  3PYZ A;  4AZ1 A;  3I80 A;  2BGE A;  3SME A;  4NWG A;  5KAC A;  3F9A A;  1C86 A;  3QCH A;  5A5F A;  3PS5 A;  1ONZ A;  3ZM6 A;  2B3O A;  4QUN A;  4ZN5 A;  2UUO A; 
#chains in the Genus database with same CATH homology
 2CNH A;  1OHD A;  4R0S A;  2C7S A;  1YGR A;  3I36 A;  4HJP A;  2AHS A;  3QCG A;  2NTA A;  1D5R A;  1XRI A;  5K23 A;  3EMU A;  3MMJ A;  3S3F A;  1MKP A;  1QZ0 A;  3AWG A;  5IBS A;  1NWE A;  2I6M A;  2NV5 A;  1PH0 A;  1ZC0 A;  4OHE A;  4WTY A;  3RGO A;  1YZ4 A;  1T48 A;  1G1F A;  2NT7 A;  3LJ8 A;  4RHG A;  4J51 A;  2PT0 A;  3MOW A;  1ECV A;  1G1H A;  2DXP A;  1NZ7 A;  1LYV A;  3BRH A;  4OHI A;  1U24 A;  3O3L A;  1OEM X;  2F6T A;  1NL9 A;  3CM3 A;  3OLR A;  5EHP A;  1G4W R;  3ZMQ A;  1L8K A;  2M3V A;  4R30 A;  5BX1 A;  2E0T A;  2Q47 A;  4NND A;  4GS0 A;  1WAX A;  1R6H A;  2CMB A;  4OHD A;  5M43 A;  3N0A A;  2BZL A;  2I1Y A;  2B07 A;  1NO6 A;  1Q6T A;  5KA1 A;  1I9T A;  4JNB A;  2J17 A;  1BZJ A;  1GWZ A;  1OHC A;  2PBN A;  2OUD A;  4WU3 A;  2F70 A;  2B4O A;  2AZR A;  1WRM A;  1T4J A;  3D1O A;  1GFY A;  2VEV A;  2FJM A;  4GE2 A;  2YDU A;  2WGP A;  2B4S A;  4NX8 A;  4BPC A;  1PTV A;  2PA5 A;  2QCJ A;  3ZMP A;  3QCN A;  3D9C A;  2F6W A;  3QCK A;  4BJO A;  5KA0 A;  1XXP A;  4GE6 A;  2R0B A;  1WCH A;  1Q6S A;  2VEY A;  3BLT A;  3QCI A;  1YTW A;  2QBQ A;  4WU2 A;  5GTJ A;  2VEX A;  3AWE A;  1U26 A;  4PYH A;  2NT2 A;  2CNF A;  3F81 A;  2VEU A;  4S0G A;  1OET A;  4TVV A;  1L8G A;  2BIJ A;  1Q6N A;  1PTY A;  4JMJ A;  3QCC A;  2I6I A;  4GE5 A;  1FPZ A;  4MBB A;  4QAH A;  2G6Z A;  2F46 A;  4D3P A;  3D1H A;  2HVL A;  3BM8 A;  2IMG A;  4H34 A;  4ICZ A;  4IKC A;  2I6O A;  3EU0 A;  5AWX A;  2HCM A;  2H4V A;  5IBM A;  2H04 A;  4H1O A;  3CWE A;  2HNQ A;  5K9W A;  2PQ5 A;  2F6Z A;  1I57 A;  1P15 A;  3S4O A;  3O4U A;  3S3E A;  5KA7 A;  5BZZ A;  2F6F A;  5KA3 A;  4WOH A;  3H2X A;  1M3G A;  4RH5 A;  2J16 B;  1G7F A;  3D44 A;  4QAP A;  2GJT A;  3ZM0 A;  2H03 A;  2GP0 A;  1EEN A;  2F6V A;  2FJN A;  3ZM3 A;  3V0D A;  1PA1 A;  4JBC A;  5BUG A;  1SUG A;  2PI7 A;  4QBE A;  2H02 A;  2ZMM A;  3S4E A;  4GRZ A;  4YAA A;  2MBC A;  5KAA A;  4DGX A;  1U25 A;  2HY3 A;  5MMZ B;  4ZRT A;  2CFV A;  1Q6M A;  2CM2 A;  1OEU A;  2BGD A;  2C46 A;  3RZ2 A;  4GFV A;  2F6Y A;  1Q6J A;  3QCL A;  4Y2E A;  1ZZW A;  3B7O A;  2I5X A;  4HRF A;  1T49 A;  3BLU A;  4QBW A;  1PTT A;  3EZZ A;  1EEO A;  3F9B A;  1YFO A;  1NNY A;  1AAX A;  2CM8 A;  2OOQ A;  2HB1 A;  4RKK A;  2QBS A;  2CM7 A;  2VEW A;  1PYN A;  1ZCL A;  5HDE A;  1V3A A;  5EHR A;  1G7G A;  2HNP A;  2Y96 A;  3GXH A;  5KA9 A;  3QKQ A;  2I4H A;  2I6P A;  4NYH A;  3QCM A;  5K22 A;  3F99 A;  3GXG A;  2ZN7 A;  2CMA A;  4QUM A;  2FH7 A;  1X24 A;  4JMK A;  3A5J A;  5KA2 A;  1PXH A;  1A5Y A;  2I4G A;  5I6V A;  2QDP A;  2NLK A;  3U96 A;  2QDM A;  2G59 A;  2Q05 A;  2CMC A;  3V0F A;  1OEO X;  3F41 A;  2BV5 A;  4D3Q A;  2QBP A;  4HJQ A;  1I9S A;  2CM3 A;  1C88 A;  3V0G A;  3S3K A;  2I42 A;  4OHL A;  4ZI4 A;  2I6J A;  3ZM1 A;  1VHR A;  2J16 A;  2Y2F A;  1YWF A;  5LXQ B;  1G4U S;  1YN9 A;  4KYR A;  1BZC A;  4KYQ A;  1RXD A;  2CJZ A;  1FPR A;  2I3R A;  2CNG A;  3V0H A;  4RI4 A;  1J4X A;  1C84 A;  2QCT A;  2F71 A;  2ESB A;  3ZM2 A;  1BZH A;  1LQF A;  4PVG A;  4GRY A;  1G1G A;  2CNE A;  4Z6B A;  1Q6P A;  3O5X A;  2P6X A;  1OEV A;  4OHH A;  3AWF A;  2GWO A;  4GFU A;  4ERC A;  2B4P A;  2B49 A;  2I3U A;  2RF6 A;  5K25 A;  1QXK A;  5K24 A;  3NME A;  3QCD A;  1OHE A;  3MOZ A;  1PTU A;  5BZX A;  2PSZ A;  2QDC A;  3QCE A;  1YTS A;  3QCF A;  3OMH A;  3D42 A;  5K9V A;  2HC1 A;  3I7Z A;  1XM2 A;  4Y14 A;  3D1Q A;  3RO1 A;  3V0I A;  4DGP A;  3EAX A;  3M4U A;  1JF7 A;  2P4D A;  4GWF A;  2H4G A;  3QKP A;  4I8N A;  1C83 A;  3V0J A;  3EB1 A;  1FQ1 A;  1PA9 A;  3A5K A;  5KA4 A;  3S3H A;  1C87 A;  2A8B A;  3O4T A;  2CNI A;  2HC2 A;  2A3K A;  2I4E A;  4B04 A;  1YPT A;  2QBR A;  4YR8 B;  4KI9 A;  4NWF A;  1LAR A;  3RGQ A;  1OES A;  2QEP A;  1ZCK A;  2I75 A;  1Q1M A;  2HXP A;  3QCB A;  2B4U A;  4D3R A;  2NZ6 A;  1JLN A;  1XXV A;  3SR9 A;  1NWL A;  2SHP A;  5KAD A;  1ONY A;  3V0E A;  1KAV A;  2H4K A;  4R0T A;  1XBO A;  4RH9 A;  1YTN A;  2OC3 A;  1YGU A;  2OZ5 A;  5KAB A;  1KAK A;  1C85 A;  2JJD A;  5KA8 A;  3O4S A;  4RDD A;  3ZV2 A;  5J8R A;  4RI5 A;  1RPM A;  3QCJ A;  4AZ1 A;  3I80 A;  2BGE A;  3SME A;  4NWG A;  5KAC A;  3F9A A;  1C86 A;  3QCH A;  3PS5 A;  1ONZ A;  2B3O A;  4QUN A;  4ZN5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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